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CDS Information : ANT_12620

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close this sectionGenomic map

Display Clone

Anaerolinea thermophila UNI-1T (= NBRC 100420T) chromosome

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Overview 
Genome
Proteome 
Clone

close this sectionLocation

Organism Anaerolinea thermophila UNI-1T (= NBRC 100420T)
Replicon chromosome
Start / Stop / Direction 1,422,901 / 1,422,086 / -
Location complement(1422086..1422901)
Type CDS
Length 816 bp (271 aa)

close this sectionAnnotation

Product formamidopyrimidine-DNA glycolase
Synonym: fapy-DNA glycosylase
Synonym: DNA-(apurinic or apyrimidinic site) lyase utM
Synonym: AP lyase utM
Gene name mutM
Functional category Genetic Information Processing
- Replication and Repair
EC number 3.2.2.23
4.2.99.18
Note This ORF product lacks a binding site (arginine residue) required for DNA binding.
KEGG pathway KO:K01248
Sequence feature

2..3 (a.a.)ACT_SITE
65 (a.a.)ACT_SITE
98 (a.a.)BINDING
117 (a.a.)BINDING
261 (a.a.)ACT_SITE
References Uniprot:O50606 Pubmed:10921868
Uniprot:O50606 Pubmed:9461446

close this sectionComputational search results

BLASTP
Database:UniProtKB:2010_04
1E=5e-58D1R960_9CHLADNA glycosylaseAlignment
2E=2e-53FPG_PARUWFormamidopyrimidine-DNA glycosylase
DNA-(apurinic or apyrimidinic site) lyase mutM		Alignment
3E=3e-53A8U9I8_9LACTDNA glycosylaseAlignment
4E=9e-53C9AMU5_ENTFCDNA glycosylaseAlignment
5E=9e-53Q3XZG5_ENTFCDNA glycosylaseAlignment
HAMAP No significant hit
InterPro
Database:interpro:26.0
IPR000191 Formamidopyrimidine-DNA glycolase (Family)
 [1-270]  3.2e-92 TIGR00577
TIGR00577   fpg: formamidopyrimidine-DNA glycosylase
 [135-221]  2.5e-26 PF06831
PF06831   H2TH
 [2-123]  2.7e-27 PF01149
PF01149   Fapy_DNA_glyco
IPR000214 Formamidopyrimidine-DNA glycolase, zinc-binding site (Binding_site)
 [237-271]  14.289 PS51066
PS51066   ZF_FPG_2
IPR000214 Formamidopyrimidine-DNA glycolase, zinc-binding site (Domain)
 [237-271]  14.289 PS51066
PS51066   ZF_FPG_2
IPR010663 Formamidopyrimidine-DNA glycolase, C-terminal (Domain)
 [243-270]  1.1e-10 PF06827
PF06827   zf-FPG_IleRS
IPR010979 Ribosomal protein S13-like, H2TH (Domain)
 [134-225]  1.1e-30 SSF46946
SSF46946   S13-like H2TH domain
IPR012319 DNA glycosylase/AP lyase, catalytic domain (Domain)
 [2-120]  23.637 PS51068
PS51068   FPG_CAT
 [2-123]  2.7e-27 PF01149
PF01149   Fapy_DNA_glyco
 [2-140]  6.1e-34 SSF81624
SSF81624   N-terminal domain of MutM-like DNA repair proteins
 [2-123]  1.7e-32 SM00898
SM00898   no description
IPR015886 Formamidopyrimidine-DNA glycolase, H2TH DNA binding (Domain)
 [135-221]  2.5e-26 PF06831
PF06831   H2TH
IPR015887 Zinc finger, formamidopyrimidine-DNA glycolase, DNA-binding site (Binding_site)
 [246-270]  PS01242
PS01242   ZF_FPG_1
SignalP No significant hit
TMHMM No significant hit
SOSUI No significant hit

close this sectionCalculated information (Amino acid sequence)

size of protein 271 amino acids
molecular mass 30,766.17 Da
pI 8.65
aa composition
AlaValLeuIlePheTrpProMetGlySer
5.2
(14aa)		5.2
(14aa)		11.4
(31aa)		6.6
(18aa)		4.8
(13aa)		1.8
(5aa)		6.3
(17aa)		1.1
(3aa)		7.4
(20aa)		7
(19aa)
ThrCysAsnGlnTyrLysHisArgAspGlu
4.4
(12aa)		1.5
(4aa)		3.3
(9aa)		6.6
(18aa)		1.1
(3aa)		3.3
(9aa)		2.2
(6aa)		9.2
(25aa)		5.2
(14aa)		6.3
(17aa)

open this sectionSequence

close this sectionCovered clones

NBRC No. clone name start stop length(bp)
G21-001-056 AT1FE70L00016A03 1,387,948 1,425,869 37,922

close this sectionDistribution of Our Microbial Genomic DNA clones

We have been distributing copies of the microbial genomic DNA clones constructed during the course of each of the genomic DNA sequencing projects.
You can find more detailed information at http://www.nbrc.nite.go.jp/e/mdna-e.html.