CDS Information : APE_2023
open/close allGenomic map
| Cell envelope and cellular processes |
| Cell wall |
| Transformation/competence |
| Transport/binding proteins and lipoproteins |
| Sensors (signal transduction) |
| Membrane bioenergetics (electron transport chain and ATP synthase) |
| Mobility and chemotaxis |
| Protein secretion |
| Cell division |
| Sporulation |
| Germination |
| Intermediary metabolism |
| Metabolism of carbohydrates and related molecules |
| Specific pathways |
| Main glycolytic pathways |
| TCA cycle |
| Metabolism of amino acids and related molecules |
| Metabolism of nucleotides and nucleic acids |
| Metabolism of lipids |
| Metabolism of coenzymes and prosthetic groups |
| Metabolism of phosphate |
| Metabolism of sulfur |
| Information pathways |
| DNA replication |
| DNA restriction/modification and repair |
| DNA recombination |
| DNA packaging and segregation |
| RNA synthesis |
| Initiation |
| Regulation |
| Elongation |
| Termination |
| RNA modification |
| Protein synthesis |
| Ribosomal proteins |
| Aminoacyl-tRNA synthetases |
| Initiation |
| Elongation |
| Termination |
| Protein modification |
| Protein folding |
| Other functions |
| Adaptation to atypical conditions |
| Detoxification |
| Antibiotic production |
| Phage-related functions |
| Transposon and IS |
| Miscellaneous |
| Similar to unknown proteins |
| From B. subtilis |
| From other organisms |
| No similarity |
Location
| Organism |
Aeropyrum pernix K1T (= NBRC 100138T) |
| Replicon |
chromosome |
| Start / Stop / Direction |
1,277,044 / 1,275,809 / - |
| Location |
complement(1275809..1277044) |
| Type |
CDS |
| Length |
1,236 bp (411 aa) |
Annotation
| Product |
cysteine desulfurase |
| Gene name |
csd |
| Functional category |
Information pathways
- Protein folding |
| EC number |
2.8.1.7 |
| Note |
|
| KEGG pathway |
|
| Sequence feature |
|
| References |
Uniprot:P77444 Pubmed:10329673,10829016 |
Proteome
Related links to external database
Computational search results
BLASTP
Database:UniProtKB:2010_04
|
|
| HAMAP |
No significant hit |
InterPro
Database:interpro:25.0
|
| IPR000192 Aminotransferase, class V/Cysteine desulfurase (Domain) |  ![[21-399] 9.30000000000011e-127 PF00266](/dogan/img/H.gif "[21-399] 9.30000000000011e-127 PF00266")
| PF00266 Aminotran_5 | | IPR000192 Aminotransferase, class V (Family) |
| PF00266 Aminotran_5 | ![[212-231] PS00595](/dogan/img/P.gif "[212-231] PS00595")
| PS00595 AA_TRANSFER_CLASS_5 | | IPR000192 Aminotransferase, class V/Cysteine desulfurase (Region) |
| PF00266 Aminotran_5 | | IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (Domain) | ![[34-295] 3.19999899046355e-80 G3DSA:3.40.640.10](/dogan/img/X2.gif "[34-295] 3.19999899046355e-80 G3DSA:3.40.640.10")
| G3DSA:3.40.640.10 PyrdxlP-dep_Trfase_major_sub1 | | IPR015424 Pyridoxal phosphate-dependent transferase, major region (Domain) | ![[4-411] 7.3e-104 SSF53383](/dogan/img/B.gif "[4-411] 7.3e-104 SSF53383")
| SSF53383 PyrdxlP-dep_Trfase_major | | IPR020578 Aminotransferase class-V pyridoxal-phosphate binding site (Binding_site) |
| PS00595 AA_TRANSFER_CLASS_5 |
|
| SignalP |
No significant hit |
| TMHMM |
No significant hit |
| SOSUI |
No significant hit |
Calculated information (Amino acid sequence)
| size of protein |
411 amino acids |
| molecular mass |
45,292.78 Da |
| pI |
6.06 |
| aa composition |
| Ala | Val | Leu | Ile | Phe | Trp | Pro | Met | Gly | Ser |
|---|
9.7
(40aa) | 9.7
(40aa) | 10.9
(45aa) | 3.9
(16aa) | 1.9
(8aa) | 1.7
(7aa) | 4.9
(20aa) | 2.9
(12aa) | 9.2
(38aa) | 5.1
(21aa) |
| Thr | Cys | Asn | Gln | Tyr | Lys | His | Arg | Asp | Glu |
|---|
4.9
(20aa) | 0.7
(3aa) | 1.7
(7aa) | 0.7
(3aa) | 2.7
(11aa) | 2.7
(11aa) | 4.1
(17aa) | 8.3
(34aa) | 4.9
(20aa) | 9.2
(38aa) |
|
Sequence
>APE_2023 cysteine desulfurase
ATGCCCAGGTTTAGCTGTTACGAGGTTAGATCCGAGTTTCCTGAGCTTGAGAGGGGTATT
GTCTATCTTGACAATGCTGCCAGCACTTTGAAGCCAAGGCGTGTTGTGGAGGCTATGAGG
GAGTTCTCGTATAGGAGCTATGCCAACGTCCATAGGGGTGTGCATAGGCTTAGCATGGAG
GCTAGTAAGGCCTATGAGGATGCGCACGAGGTTGTCGCCAGGCTGGTCGGGGGGAGTTGG
GACGAGGTCGTGTTCACCCGCAATACTACGGAGGCGATGCAGCTGGCCGCACTTACCCTA
GCCTACAACGGGCTCCTAAGGGGCGGCGAGGTCCTCGTGACCGCGGCTGACCACCACTCC
ACTCTACTACCCTGGGTCAGGGCGGCCAGACTGGGGGGTGGTAGGGCGAGGATACTCCCC
CTCGACGGCCGGGGGGTTCCTAGGTGGGACCTGCTCGAGGACTATATAACCGAGGATACC
AGGGCGGTGGCAGTAGGCCACGTATCCAACGTTACGGGGGTGGTGGCCCCTGTGGAGGAT
ATAGTTAAGGCTGCAAAGAAGGTGGGCGCCCTGGTCGTGCTCGACTCGGCCCAGGGGGTG
CCACACCTGCCAGTAGACTTCAGGAGGATGGGGGTCGATATGGCGGCGTTCAGCGGCCAT
AAGATGCTGGGGCCCACGGGCATTGGTGTCCTGTGGGCCAGGAGGGACCTTCTCGAGGAG
CTCGAGCCACCCCTGGGAGGGGGAGGGACTGTGTCGAGGGTTAGACTGCAGGGGGGCTCT
GTGGAGATAGAGTGGGAGGAGCCGCCGTGGAAGTTCGAGGCAGGAACCCCGCCTATAATA
GAGGCCGTCGGCCTGGCGGAGGCCGCTAACATGCTCATGGAGATTGGTATGGAGCATGTT
GCGAGGCATGAGGACGAGCTGACGAGCCACACGATGAAGCTGCTGGAGCCCCTCTACAGT
GAAGGCCTGATACGCTATGTGGGCCCCGACAAGCCGGGTGAGAGGCACGGTATAGTCTCT
ATAACCACCCACCTGAAAAGCCCCGACGAGCTAGGCCTCCTCCTCGACAGGAGGGGCATA
GCCGTGAGGACAGGCCTACACTGCGCCCACATACTACACGACCATGTGGATGCCAGCATG
GGTAGCGTGTGGGCAAGCTTCTACATATACAACTGCAAGGAGGATGCCGAGAGGCTCGCA
GAAGCACTAGAGGAGATACTCACCACGAGGAGGTAA
>APE_2023 cysteine desulfurase
MPRFSCYEVRSEFPELERGIVYLDNAASTLKPRRVVEAMREFSYRSYANVHRGVHRLSME
ASKAYEDAHEVVARLVGGSWDEVVFTRNTTEAMQLAALTLAYNGLLRGGEVLVTAADHHS
TLLPWVRAARLGGGRARILPLDGRGVPRWDLLEDYITEDTRAVAVGHVSNVTGVVAPVED
IVKAAKKVGALVVLDSAQGVPHLPVDFRRMGVDMAAFSGHKMLGPTGIGVLWARRDLLEE
LEPPLGGGGTVSRVRLQGGSVEIEWEEPPWKFEAGTPPIIEAVGLAEAANMLMEIGMEHV
ARHEDELTSHTMKLLEPLYSEGLIRYVGPDKPGERHGIVSITTHLKSPDELGLLLDRRGI
AVRTGLHCAHILHDHVDASMGSVWASFYIYNCKEDAERLAEALEEILTTRR
