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CDS Information : PH0011.1

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close this sectionGenomic map

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Pyrococcus horikoshii OT3T (= NBRC 100139T) chromosome

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Overview 
Genome

close this sectionLocation

Organism Pyrococcus horikoshii OT3T (= NBRC 100139T)
Replicon chromosome
Start / Stop / Direction 9,318 / 8,476 / -
Location complement(8476..9318)
Type CDS
Length 843 bp (280 aa)

close this sectionAnnotation

Product nicotinate-nucleotide pyrophosphorylase [carboxylating]
Gene name nadC
Functional category Metabolism
- Metabolism of Cofactors and Vitamins
EC number 2.4.2.19
Note
KEGG pathway
Sequence feature
References Uniprot:P30011 Pubmed:8561507
Uniprot:P30012 Pubmed:8419294,9016724

close this sectionComparative genome

Table
Display BBH1e-1001e-501e-101e-3
Pyrococcus abyssi GE5Pyrococcus furiosus DSM 3638Thermococcus kodakaraensis KOD1
[14] PAB2347 1e-124(437)
nicotinate-nucleotide pyrophosphorylase (EC:2.4.2.19)(nadC)
[2031] PF1978 1e-120(424)
nicotinate-nucleotide pyrophosphorylase (EC:2.4.2.19)
[218] TK0218 3e-118(416)
nicotinate-nucleotide pyrophosphorylase (EC:2.4.2.19)

close this sectionRelated links to external database

UniProtO57769 : N-term changed (+9)
INSDBAA29079.1 (DDBJ GenBank EMBL) : N-term changed (+9)
RefSeqNP_142034.1 : N-term changed (+9)
GI14589973 : N-term changed (+9)
GeneID1443913 : N-term changed (+9)
UniParcUPI00000667A3 : N-term changed (+9)

close this sectionComputational search results

BLASTP
Database:UniProtKB:12.5
1E=1e-149O57769_PYRHO283aa long hypothetical nicotinate-nucleotide pyrophosphorylaseAlignment
2E=1e-129Q9V2R4_PYRABNadC nicotinate-nucleotide pyrophosphorylaseAlignment
3E=1e-125Q8TZL2_PYRFUNicotinate-nucleotide pyrophosphorylase
Quinolinate phosphoribosyltransferase (Decarboxylating)		Alignment
4E=1e-122Q5JFR0_PYRKONicotinate-nucleotide pyrophosphorylaseAlignment
5E=3e-86A3CTQ4_METMJNicotinate-nucleotide pyrophosphorylaseAlignment
HAMAP No significant hit
InterPro
Database:interpro:16.0
IPR002638 Quinolinate phosphoribosyl transferase (Domain)
 [15-102]  1.2e-47 PF02749
PF02749   QRPTase_N
 [104-274]  1.4e-48 SSF51690
SSF51690   Quinolinic acid phosphoribosyltransferase (Nicotinate-nucleotide pyrophosphorylase, NadC), C-terminal domain
 [104-272]  3.4e-97 PF01729
PF01729   QRPTase_C
IPR002638 Quinolinate phosphoribosyl transferase (Family)
 [104-272]  3.4e-97 PF01729
PF01729   QRPTase_C
 [15-102]  1.2e-47 PF02749
PF02749   QRPTase_N
 [104-274]  1.4e-48 SSF51690
SSF51690   Quinolinic acid phosphoribosyltransferase (Nicotinate-nucleotide pyrophosphorylase, NadC), C-terminal domain
 [112-273]  1e-76 PD003988
PD003988   O57769_PYRHO_O57769;
IPR004393 Nicotinate-nucleotide pyrophosphorylase (Family)
 [6-273]  1.4e-163 TIGR00078
TIGR00078   nadC: nicotinate-nucleotide pyrophosphoryla
IPR013785 Aldolase-type TIM barrel (Domain)
 [107-273]  8.5e-48 G3DSA:3.20.20.70
G3DSA:3.20.20.70   no description
SignalP No significant hit
TMHMM No significant hit
SOSUI No significant hit

close this sectionCalculated information (Amino acid sequence)

size of protein 280 amino acids
molecular mass 31,038.15 Da
pI 5.84
aa composition
AlaValLeuIlePheTrpProMetGlySer
8.2
(23aa)		12.5
(35aa)		9.3
(26aa)		8.9
(25aa)		2.1
(6aa)		0
(0aa)		3.2
(9aa)		2.1
(6aa)		6.8
(19aa)		4.6
(13aa)
ThrCysAsnGlnTyrLysHisArgAspGlu
2.5
(7aa)		0
(0aa)		3.6
(10aa)		0.7
(2aa)		2.5
(7aa)		8.9
(25aa)		1.4
(4aa)		6.1
(17aa)		5.4
(15aa)		11.1
(31aa)

open this sectionSequence