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CDS Information : PH0039.1

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close this sectionGenomic map

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Pyrococcus horikoshii OT3T (= NBRC 100139T) chromosome

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Overview 
Genome

close this sectionLocation

Organism Pyrococcus horikoshii OT3T (= NBRC 100139T)
Replicon chromosome
Start / Stop / Direction 37,461 / 36,523 / -
Location complement(36523..37461)
Type CDS
Length 939 bp (312 aa)

close this sectionAnnotation

Product cytosine-specific DNA methylase
Gene name
Functional category Genetic Information Processing
- DNA Replication and Repair
EC number 2.1.1.37
Note
KEGG pathway
Sequence feature

82 (a.a.)ACT_SITE
References Uniprot:P50192 Pubmed:8759008
Uniprot:P05302 Pubmed:2823226

close this sectionComparative genome

Table
Display BBH1e-1001e-501e-101e-3
Pyrococcus abyssi GE5Pyrococcus furiosus DSM 3638Thermococcus kodakaraensis KOD1
[57] PAB2317 8e-133(465)
modification methylase
[49] PF0049 7e-130(455)
cytosine-specific DNA-methyltransferase

close this sectionRelated links to external database

UniProtO57741 : N-term changed (-222)
INSDBAA29107.1 (DDBJ GenBank EMBL) : N-term changed (-222)
RefSeqNP_142059.1 : N-term changed (-222)
GI14589996 : N-term changed (-222)
GeneID1443939 : N-term changed (-222)
UniParcUPI0000062CDE : N-term changed (-222)

close this sectionComputational search results

BLASTP
Database:UniProtKB:12.5
1E=1e-141Q9V2M5_PYRABCitosine-specific modificatrion methylaseAlignment
2E=1e-138Q8U4N2_PYRFUSite-specific DNA-methyltransferase
Cytosine-specific		Alignment
3E=1e-138O57741_PYRHO238aa long hypothetical modification methylaseAlignment
4E=8e-92Q8TV73_METKASite-specific DNA methylaseAlignment
5E=7e-85A3DN08_STAMFDNA-cytosine methyltransferaseAlignment
HAMAP No significant hit
InterPro
Database:interpro:16.0
IPR001525 C-5 cytosine-specific DNA methylase (Domain)
 [14-312]  1.7e-50 PTHR10629
PTHR10629   MODIFICATION METHYLASE
 [11-27]  2.4e-16 PR00105 [120-134]  2.4e-16 PR00105 [161-174]  2.4e-16 PR00105
PR00105   C5METTRFRASE
 [12-303]  2.5e-31 TIGR00675
TIGR00675   dcm: DNA-cytosine methyltransferase
 [10-171]  4e-40 PF00145 [230-305]  5.5e-17 PF00145
PF00145   DNA_methylase
IPR001525 C-5 cytosine-specific DNA methylase (Family)
 [11-27]  2.4e-16 PR00105 [120-134]  2.4e-16 PR00105 [161-174]  2.4e-16 PR00105
PR00105   C5METTRFRASE
 [10-171]  4e-40 PF00145 [230-305]  5.5e-17 PF00145
PF00145   DNA_methylase
 [12-303]  2.5e-31 TIGR00675
TIGR00675   dcm: DNA-cytosine methyltransferase
 [14-312]  1.7e-50 PTHR10629
PTHR10629   MODIFICATION METHYLASE
SignalP No significant hit
TMHMM No significant hit
SOSUI No significant hit

close this sectionCalculated information (Amino acid sequence)

size of protein 312 amino acids
molecular mass 36,010.59 Da
pI 10.52
aa composition
AlaValLeuIlePheTrpProMetGlySer
6.4
(20aa)		8.3
(26aa)		6.1
(19aa)		8
(25aa)		7.4
(23aa)		1.3
(4aa)		9
(28aa)		1.3
(4aa)		6.7
(21aa)		4.5
(14aa)
ThrCysAsnGlnTyrLysHisArgAspGlu
1.6
(5aa)		0.3
(1aa)		4.8
(15aa)		2.2
(7aa)		2.9
(9aa)		4.8
(15aa)		1
(3aa)		11.5
(36aa)		4.5
(14aa)		7.4
(23aa)

open this sectionSequence