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CDS Information : STMDT12_C00010

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Salmonella enterica serovar Typhimurium T000240 Chromosome

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Overview 
Genome

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Organism Salmonella enterica serovar Typhimurium T000240
Replicon Chromosome
Start / Stop / Direction 337 / 2,799 / +
Location 337..2799
Type CDS
Length 2,463 bp (820 aa)

close this sectionAnnotation

Product bifunctional aspartate kinase I/homoserine dehydrogenase I
Gene name thrA
Functional category Metabolism
- [E] Amino acid transport and metabolism
EC number 2.7.2.4
Note COG0527 Aspartokinases
KEGG pathway
Sequence feature
References Family/Domain:CDD-137283

close this sectionComputational search results

BLASTP
Database:UniProtKB:2010_04
1E=0Q8ZS19_SALTYAspartokinase IAlignment
2E=0D0ZIQ1_SALT1Bifunctional aspartokinase I/homeserine dehydrogenase IAlignment
3E=0A9MXH0_SALPBPutative uncharacterized proteinAlignment
4E=0C9X5D6_SALTDAspartokinase I/homoserine dehydrogenase IAlignment
5E=0B5Q2N5_SALVIAspartokinase/homoserine dehydrogenase IAlignment
HAMAP No significant hit
InterPro
Database:interpro:26.0
IPR001048 Aspartate/glutamate/uridylate kinase (Domain)
 [2-284]  5.1e-44 PF00696
PF00696   AA_kinase
 [1-295]  6e-28 SSF53633
SSF53633   Carbamate kinase-like
 [3-297]  1.3e-14 G3DSA:3.40.1160.10
G3DSA:3.40.1160.10   no description
IPR001341 Aspartate kinase region (Domain)
 [3-11]  PS00324
PS00324   ASPARTOKINASE
 [1-461]  3.7e-235 TIGR00657
TIGR00657   asp_kinases: aspartate kinase
IPR001342 Homoserine dehydrogenase (Domain)
 [660-682]  PS01042
PS01042   HOMOSER_DHGENASE
 [614-811]  1.7e-50 PF00742
PF00742   Homoserine_dh
IPR002912 Amino acid-binding ACT (Domain)
 [324-377]  1.8e-07 PF01842 [401-447]  1.9e-07 PF01842
PF01842   ACT
IPR005106 Homoserine dehydrogenase, NAD-binding (Domain)
 [472-605]  9.9e-30 PF03447
PF03447   NAD_binding_3
IPR011147 Bifunctional aspartokinase/homoserine dehydrogenase I (Family)
 [1-818]  PIRSF000727
PIRSF000727   Bifunctional aspartokinase/homoserine dehydrogenase I
IPR016040 NAD(P)-binding domain (Domain)
 [462-647]  1e-60 G3DSA:3.40.50.720
G3DSA:3.40.50.720   no description
 [462-636]  3.3e-43 SSF51735
SSF51735   NAD(P)-binding Rossmann-fold domains
IPR018042 Aspartate kinase, conserved site (Conserved_site)
 [3-11]  PS00324
PS00324   ASPARTOKINASE
IPR019811 Homoserine dehydrogenase, conserved site (Conserved_site)
 [660-682]  PS01042
PS01042   HOMOSER_DHGENASE
SignalP No significant hit
TMHMM No significant hit
SOSUI No significant hit

close this sectionCalculated information (Amino acid sequence)

size of protein 820 amino acids
molecular mass 88,694.85 Da
pI 6.03
aa composition
AlaValLeuIlePheTrpProMetGlySer
11.3
(93aa)		8.2
(67aa)		11
(90aa)		5.9
(48aa)		3.7
(30aa)		0.5
(4aa)		3.7
(30aa)		2.8
(23aa)		7.9
(65aa)		6.5
(53aa)
ThrCysAsnGlnTyrLysHisArgAspGlu
4
(33aa)		1.5
(12aa)		4.6
(38aa)		4
(33aa)		2.2
(18aa)		3.9
(32aa)		1.8
(15aa)		5.6
(46aa)		5.6
(46aa)		5.4
(44aa)

open this sectionSequence