CDS Information : STMDT12_C18000
open/close allGenomic map
| Information storage and processing |
| [J] Translation, ribosomal structure and biogenesis |
| [A] RNA processing and modification |
| [K] Transcription |
| [L] Replication, recombination and repair |
| Cellular processes and signaling |
| [D] Cell cycle control, cell division, chromosome partitioning |
| [V] Defense mechanisms |
| [T] Signal transduction mechanisms |
| [M] Cell wall/membrane/envelope biogenesis |
| [N] Cell motility |
| [U] Intracellular trafficking, secretion, and vesicular transport |
| [O] Posttranslational modification, protein turnover, chaperones |
| Metabolism |
| [C] Energy production and conversion |
| [G] Carbohydrate transport and metabolism |
| [E] Amino acid transport and metabolism |
| [F] Nucleotide transport and metabolism |
| [H] Coenzyme transport and metabolism |
| [I] Lipid transport and metabolism |
| [P] Inorganic ion transport and metabolism |
| [Q] Secondary metabolites biosynthesis, transport and catabolism |
| Poorly characterized |
| [R] General function prediction only |
| [S] Function unknown |
| Unannotated |
Location
| Organism |
Salmonella enterica serovar Typhimurium T000240 |
| Replicon |
Chromosome |
| Start / Stop / Direction |
1,873,986 / 1,874,837 / + |
| Location |
1873986..1874837 |
| Type |
CDS |
| Length |
852 bp (283 aa) |
Annotation
| Product |
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase |
| Gene name |
ipk |
| Functional category |
Metabolism
- [I] Lipid transport and metabolism |
| EC number |
2.7.1.148 |
| Note |
COG1947 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase |
| KEGG pathway |
|
| Sequence feature |
|
| References |
Family/Domain:CDD-134232 |
Computational search results
BLASTP
Database:UniProtKB:2010_04
|
| 1 | E=1e-164 | D0ZJ51_SALT1 | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | Alignment |
|---|
| 2 | E=1e-164 | C9X5V7_SALTD | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | Alignment |
|---|
| 3 | E=1e-164 | ISPE_SALTY | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase | Alignment |
|---|
| 4 | E=1e-164 | ISPE_SALTI | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase | Alignment |
|---|
| 5 | E=1e-163 | ISPE_SALPC | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase | Alignment |
|---|
|
| HAMAP |
No significant hit |
InterPro
Database:interpro:26.0
|
| IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase (Family) |  ![[1-283] 1.8e-170 TIGR00154](/dogan/img/T.gif "[1-283] 1.8e-170 TIGR00154")
| TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D | ![[1-281] 2.4e-125 PIRSF010376](/dogan/img/S.gif "[1-281] 2.4e-125 PIRSF010376")
| PIRSF010376 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase | ![[3-275] 32.144 MF_00061](/dogan/img/G.gif "[3-275] 32.144 MF_00061")
| MF_00061 ISPE_MF_00061 | | IPR006204 GHMP kinase (Domain) | ![[91-148] 8.3e-10 PF00288](/dogan/img/H.gif "[91-148] 8.3e-10 PF00288")
| PF00288 GHMP_kinases_N | | IPR013750 GHMP kinase, C-terminal (Domain) |
| PF08544 GHMP_kinases_C | | IPR014721 Ribosomal protein S5 domain 2-type fold (Domain) | ![[3-165] 1.2e-48 G3DSA:3.30.230.10](/dogan/img/X2.gif "[3-165] 1.2e-48 G3DSA:3.30.230.10")
| G3DSA:3.30.230.10 no description | | IPR020568 Ribosomal protein S5 domain 2-type fold (Domain) | ![[1-163] 1.1e-52 SSF54211](/dogan/img/B.gif "[1-163] 1.1e-52 SSF54211")
| SSF54211 Ribosomal protein S5 domain 2-like |
|
| SignalP |
No significant hit |
| TMHMM |
No significant hit |
| SOSUI |
No significant hit |
Calculated information (Amino acid sequence)
| size of protein |
283 amino acids |
| molecular mass |
30,883.41 Da |
| pI |
5.81 |
| aa composition |
| Ala | Val | Leu | Ile | Phe | Trp | Pro | Met | Gly | Ser |
|---|
9.2
(26aa) | 7.1
(20aa) | 13.4
(38aa) | 4.2
(12aa) | 3.9
(11aa) | 1.8
(5aa) | 6.7
(19aa) | 1.4
(4aa) | 8.5
(24aa) | 5.3
(15aa) |
| Thr | Cys | Asn | Gln | Tyr | Lys | His | Arg | Asp | Glu |
|---|
5.7
(16aa) | 1.8
(5aa) | 3.9
(11aa) | 2.5
(7aa) | 1.8
(5aa) | 3.2
(9aa) | 3.2
(9aa) | 5.3
(15aa) | 4.6
(13aa) | 6.7
(19aa) |
|
Sequence
>STMDT12_C18000 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
ATGATGACCCATTGGCCTTCTCCGGCAAAATTAAATCTGTTTTTATATATCACCGGACAG
CGAGCAGACGGCTACCACACGCTGCAGACGCTGTTTCAGTTTCTGGATTATGGCGACACA
CTCCACATCGAACCGCGTCACGATGGCGAAATCCATTTATTAACGCCGGTTAACGGCGTT
GAAAATGAAGACAATCTGATCGTCCGTGCCGCGCGGCTGTTGATGAAAGTCGCCTCGGAG
AGTGGGCGCCTGCCCGCCGGAAGCGGTGCGGATATCAGCATTGAGAAGCGCCTTCCCATG
GGCGGCGGTCTGGGCGGCGGCTCATCTAACGCCGCGACCGTTCTGGTGGCGCTCAATCAT
CTTTGGCAATGCGGGCTTTCCATTGATGAACTGGCGACGCTCGGCCTGACGCTCGGCGCC
GACGTCCCGGTCTTTGTTCGTGGCCACGCCGCGTTTGCCGAAGGCGTAGGCGAAATATTA
ACGCCGGTGAATCCGCCGGAAAAATGGTATCTGGTCGCGCACCCTGGCGTAAGCATTCCC
ACACCGGTTATCTTTAAAGATCCTCAATTGCCGCGTAATACGCCAAAAAGGTCAATAGAT
ACGTTACTAAAATGTGAATTCAGCAATGATTGCGAGGTTATCGCAAGAAAACGTTTTCGC
GAGGTTGATGCGGCGCTTTCCTGGCTGTTAGAATACGCGCCGTCGCGCCTGACTGGGACA
GGGGCCTGTGTCTTTGCTGAATTCGATACAGAGTCTTGTGCTCGCCAGGTGCTTGAGCAA
GCCCCGGAATGGCTCAATGCTTTTGTGGCGAAGGGTGTCAACCTCTCCCCATTGCATCGA
GAGTTACTCTAA
>STMDT12_C18000 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
MMTHWPSPAKLNLFLYITGQRADGYHTLQTLFQFLDYGDTLHIEPRHDGEIHLLTPVNGV
ENEDNLIVRAARLLMKVASESGRLPAGSGADISIEKRLPMGGGLGGGSSNAATVLVALNH
LWQCGLSIDELATLGLTLGADVPVFVRGHAAFAEGVGEILTPVNPPEKWYLVAHPGVSIP
TPVIFKDPQLPRNTPKRSIDTLLKCEFSNDCEVIARKRFREVDAALSWLLEYAPSRLTGT
GACVFAEFDTESCARQVLEQAPEWLNAFVAKGVNLSPLHRELL
