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Data Download
FunctionIDDescription
Acid resistance (by GABA antiporter)NFUNC_0071The gad system helps to maintain a near-neutral intracellular pH when cells are exposed to extremely acidic conditions. Imports glutamate inside the cell while simultaneously exporting to the periplasm the GABA produced by GadA and GadB.
Alanine racemizationNFUNC_0063Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.
Alginate degradationNFUNC_0062Depolymerizes alginate by cleaving the beta-1,4 glycosidic bond.
n-alkane hydroxylationNFUNC_0008Alkane 1-monooxygenase (NRULE_0024) catalyzes the hydroxylation of n-alkanes and fatty acids in the presence of a NADH-rubredoxin reductase (NRULE_0040) and rubredoxin (NRULE_0039).
D-allose biosynthesisNFUNC_0077D-allose biosynthesis from D-psicose by L-rhamnose isomerase. D-allose, a kind of rare sugar, exhibits many pharmaceutical activities.
Aminoglycoside resistance (by aminoglycoside N-acetyltransferase)NFUNC_0041Resistance to aminoglycoside antibiotics by acetylation of aminoglycoside catalyzed by aminoglycoside N-acetyltransferase.
Aminoglycoside resistance (by aminoglycoside O-nucleotidyltransferase)NFUNC_0042Resistance to aminoglycoside antibiotics by adenylation of aminoglycoside catalyzed by aminoglycoside O-nucleotidyltransferase.
Aminoglycoside resistance (by aminoglycoside O-phosphotransferase)NFUNC_0043Resistance to aminoglycoside antibiotics by phosphorylation of aminoglycoside catalyzed by aminoglycoside O-phosphotransferase.
Ampicillin resistanceNFUNC_0046Class A beta-lactamase TEM (P62593) is used as a marker in many commonly used cloning vectors, such as pBR322 and the pUC series.
Aniline degradation (conversion into catechol)NFUNC_0075Aniline is converted into catechol via gamma-glutamylanilide. Catechol degradated via beta-ketoadipate pathway.
Anthranilate biosynthesisNFUNC_0038Biosynthesis of Anthranilate from chorismate. Participates in the biosynthesis of L-tryptophan (Trp).
Anthranilate degradation (via hydroxylation)NFUNC_0018Degradation of anthranilate via hydroxylation pathway. This aerobic pathway converts anthranilate to catechol in a single step.
Arginine degradationNFUNC_0074Degradation of L-arginine into L-ornithine by arginase.
Aromatic azo compounds degradationNFUNC_0073Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines.
Aromatic hydrocarbon degradation (via hydroxylation by dioxygenase)NFUNC_0016The initial step of the aerobic degradation system of aromatic compounds is hydroxylation by dioxygenase (to cis-dihydrodiol compounds)The second step is reduction by cis-dihydrodiol dehydrogenase (to extradiol).
Arsenical resistanceNFUNC_0004One of the arsenic detoxification system involved in arsenical resistance. Reduction of arsenate [As(V)] to arsenite [As(III)] by arsenate reductases, and extrusion of arsenite by pumps.
Artificial lacto-N-biose biosynthesisNFUNC_0026Nishimoto and Kitaoka reported that a one-pot enzymatic reaction to produce lacto-N-biose I (LNB) utilizing four enzymes, SP (NRULE_0109), GalT (NRULE_0110), GalE (NRULE_0111) and LNBP (NRULE_0112).
Bacitracin resistanceNFUNC_0022Resistance to bacitracin by dephosphorylation of undecaprenyl diphosphate (UPP).
Benzoate degradation (via hydroxylation by dioxygenase)NFUNC_0017The initial step of the aerobic benzoate degradation system is hydroxylation by benzoate 1,2-dioxygenase (to 2-hydro-1,2-dihydroxybenzoate). The second step is reduction by 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase (to catechol).
Beta-lactam antibiotic resistanceNFUNC_0033Resistance to beta-lactam antibiotics by beta-lactamase that hydrolyzes the beta-lactam amide bond.
Betaine biosynthesis (from choline)NFUNC_0049Betaine biosynthesis pathway using choline as starting material. Betaine accumulates as a compatible solute in several halotolerant microorganisms.
Betaine biosynthesis (from glycine)NFUNC_0050Betaine biosynthesis pathway using glycine as starting material. Betaine accumulates as a compatible solute in several halotolerant microorganisms.
Bioplastic degradationNFUNC_0015Degradation of bioplastics by microbial poly(3-hydroxyalkanoate) depolymerase or D-(-)-3-hydroxybutyrate oligomer hydrolase.
Bioplastic synthesisNFUNC_0001Biosynthesis of polyhydroxyalkanoates (PHAs). PHAs are carbon and energy storage polyesters that accumulate as intracellular granules in many bacteria and archaea, in response to environmental conditions.
Biotin biosynthesisNFUNC_0051Biosynthesis of biotin, a B-group vitamin. Biotin has essential metabolic functions as the CO2-carrying prosthetic group of selected carboxylases, decarboxylases and transcarboxylases. De novo biosynthesis pathway involved the conversion of pimeloyl-CoA (i.e 6-carboxyhexanoyl-CoA) to biotin.
Bleomycin resistanceNFUNC_0021Resistance to bleomycin by bleomycin-binding protein.
Catechol degradation (beta-ketoadipate pathway)NFUNC_0013Ortho cleavage of catechol (1,2-dihydroxybenzene) leads to beta-ketoadipate (3-oxoadipate), which is subsequently converted to succinyl-coenzyme A (CoA) and acetyl-CoA.
Cephalosporin resistanceNFUNC_0048Resistance to cephalosporin by beta-lactamase class C that hydrolyzes the beta-lactam amide bond.
Chloramphenicol resistanceNFUNC_0025Resistance to chloramphenicol by addition of an acetyl group to antibiotics.
Chlorocatechol degradation (beta-ketoadipate pathway)NFUNC_0104Degradation pathway of chlorocatechol compounds. Ortho cleavage of chlorocatechol leads to beta-ketoadipate (3-oxoadipate), which is subsequently converted to succinyl-coenzyme A (CoA) and acetyl-CoA.
Cyclodextrin biosynthesisNFUNC_0076Cyclizes part of a (1->4)-alpha-D-glucan chain by formation of a (1->4)-alpha-D-glucosidic bond.
Dibenzothiophene degradation (via desulfurization)NFUNC_0029One of dibenzothiophene (DBT) biodegradation pathway is oxidative desulfurization (also called 4S pathway).DBT monooxygenase (NRULE_0105) converts DBT to DBT-sulfone (DBT-5-oxide or DBT-5,5-dioxide).DBT-5,5-dioxide monooxygenase (NRULE_0103) converts DBT-5,5-dioxide to 2-hydroxybiphenyl-2-sulfinate (2-HBPS). These monooxygenases require FAD as cofactor, accompanied by a flavin reductase (NRULE_0101).2-HBPS is converted to 2-hydroxybiphenyl and sulfinate by desulfinase (NRULE_0104) at the last step.
1,3-dichloropropene degradationNFUNC_0012Degradation 1,3-dichloropropene into acetaldehyde via 3-chloroacrylic acid.
Dihydroxy aromatic compounds degradation (via meta-cleavage pathway)NFUNC_0011Degradation of dihydroxy aromatic compounds via meta-cleavage pathway.
Ectoine biosynthesisNFUNC_0056Ectoine accumulates as a compatible solute in several halophilic bacteria.
Equol biosynthesisNFUNC_0081Biosynthesis of phytoestrogen equol from daidzein which belongs to the isoflavones.
Extracellular electron transfer systemNFUNC_0098One of the extracellular electron transfer system of some dissimilatory metal-reducing bacteria (such as Shewanella).They can use an extracellular metal ion as terminal electron acceptors for anaerobic respiration.In metal-reduction of them, required this system which consists of inner membrane-bound, periplasmic and outer membrane multiheme c-type cytochromes, and outer membrane beta-barrel protein.
Folate biosynthesisNFUNC_0044Biosynthesis of folic acid (vitamin B9).
Fosfomycin resistanceNFUNC_0023Resistance to fosfomycin by modification of antibiotics.
Freeze resistance (by antifreeze protein)NFUNC_0019Addition of antifreeze proteins lead to prevention of cellular damage at sub-zero temperatures by lowering the freezing point and inhibition of ice growth.
GABA biosynthesisNFUNC_0066Converts glutamate to gamma-aminobutyrate (GABA), consuming one intracellular proton in the reaction.
Gentamicin resistanceNFUNC_0053Resistance to gentamicin by adenylating the 2'-hydroxyl group of antibiotics.
O-Glycan degradationNFUNC_0084Endo-alpha-N-acetylgalactosaminidase (NRULE_0257) catalyzes the liberation of galactosyl beta1,3-N-acetyl-D-galactosamine (Galbeta1,3GalNAc) alpha-linked to serine or threonine residues from mucin-type glycoproteins.
Haloalkane degradation (conversion into hydroxyacid)NFUNC_0010Degradation haloalkane into hydroxyacid via haloalcanoic acid.
Histamine biosynthesisNFUNC_0078Biosynthesis of histamine by the decarboxylation of histidine.
Human milk oligosaccharides metabolismNFUNC_0083The galacto-N-biose/lact-N-biose I metabolic pathway in the infant gastrointestinal tract.
Hyaluronan biosynthesisNFUNC_0064Catalyzes the alternate addition of N-acetylglucosamine and glucuronic acid from their respective UDP-sugar precursors to form the hyaluronic acid polymer.
Hyaluronan degradationNFUNC_0069Depolymerizes hyaluronan by cleaving the beta-1,4 glycosidic linkage between N-acetyl-beta-D-glucosamine and D-glucuronic acid residues.
Hydroxyectoine biosynthesisNFUNC_0057Hydroxyectoine accumulates as a compatible solute in several halophilic bacteria.
4-hydroxyphenylacetate degradationNFUNC_0068Degrading 4-hydroxyphenylacetate by first converting it into 3,4-dihydroxyphenylacetate (homoprotocatechuate), which is then degraded into TCA cycle intermediates via an inducible meta-cleavage pathway.
Hygromycin resistanceNFUNC_0055Resistance to hygromycin by phosphorylation of antibiotics.
Ice nucleationNFUNC_0024Ice nucleation proteins promote the nucleation of ice at relatively high temperature (above -5 degree Celsius).
Kanamycin resistanceNFUNC_0052Aminoglycoside 3'-phosphotransferase encoded by Tn903 (P00551) is used as a selective marker in some cloning vectors, such as pHSG298 and pHSG299.
Macrolide antibiotic resistanceNFUNC_0045Resistance to macrolide antibiotics by modification of 23S rRNA, active efflux or hydrolyzing of antibiotics.
Malolactic fermentationNFUNC_0070Malolactic fermentation (MLF) is one of the wine manufacturing processes. MLF consists in the conversion of the L-malate into the L-lactate and CO2 by malolactic enzyme. It is beneficial in that it reduces the acidity of wine, improves its taste and aromas and contributes to its microbiological stability.
Mercury resistanceNFUNC_0005Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase.
Metal-binding proteinNFUNC_0105A part of bacterial metal-binding proteins (such as metal-responsive transcriptional regulator, metallothionein, molbindin) are involved in metal homeostasis and resistance of cell.
MetallothioneinNFUNC_0006May play a role in essential metal ion homeostasis (especially zinc homeostasis) and resistance to certain non-essential metal ions. Metallothioneins have a high content of cysteine residues that bind various heavy metals.
Methicillin resistanceNFUNC_0035Resistance to methicillin by beta-lactam-inducible penicillin-binding protein.
Milk clottingNFUNC_0072Microbial milk-clotting protease are used as calf rennet substitutes in the cheese industry. It agglutinates milk by cleavage of kappa-casein.
Molybdate transport (ABC transporter)NFUNC_0097Molybdate is transported in bacteria by a ATP-binding cassette transporter (ABC transporter). In some organisms, molybdate transport genes are regulated by a molybdate-dependent transcriptional regulator ModE (NRULE_0323).
Mycosamine biosynthesisNFUNC_0095Biosynthesis of mycosamine (3,6-dideoxy-3-aminomannose) or perosamine (4,6-dideoxy-4-aminomannose) in Actinobacteria. These sugars might be glycosylated to aglycones by glycosyltransferase (NRULE_0341), forming secondary metabolites such as polyene antibiotics.
Naphthalene degradation (via hydroxylation by dioxygenase)NFUNC_0067Naphthalene is catabolized through cis-dihydrodiol naphthalene, salicylaldehyde, and salicylate. The latter is converted into either catechol (by 1-hydroxylase), which is then degraded by either the meta or the ortho cleavage pathways to TCA cycle intermediates, or to gentisate (by 5-hydroxylase), which is degraded by a different pathway to TCA cycle intermediates.
Nitrile hydrataseNFUNC_0002Nitrile hydratase is used for industrial production of acrylamide.
NitrogenaseNFUNC_0094A nitrogenase consists of a dinitrogenase which catalyzes the key enzymatic reactions and a nitrogenase reductase. A nitrogenase converts the substrate (N2) to the product (NH3).
(R)-pantothenate biosynthesisNFUNC_0030Biosynthesis of (R)-pantothenate, also called vitamin B5 or D-pantothenic acid. (R)-pantothenate results from the condensation of beta-alanine and D-pantoate.
Penicillin resistanceNFUNC_0047Resistance to penicillin by beta-lactamase A or D that hydrolyzes the beta-lactam amide bond.
Phenol degradationNFUNC_0028The initial step of the aerobic degradation system of phenol derivatives is hydroxylation by monooxygenases (to catechol derivatives).
Phytic acid hydrolysisNFUNC_0085Hydrolyze phytic acid.
Polymyxin resistanceNFUNC_0036Resistance to polymyxin by attaching 4-amino-4-deoxy-L-arabinose (L-Ara4N) to lipid A.
Polyurethane degradationNFUNC_0080Degradation of polyurethane. Polyurethanase A (NRULE_0250) play a more major role in polyurethane degradation than Polyurethanase B (NRULE_0251) based on cell density and growth rates.
Protocatechuate degradation (beta-ketoadipate pathway)NFUNC_0014Ortho cleavage of protocatechuate (3,4-dihydroxybenzoate) leads to beta-ketoadipate (3-oxoadipate), which is subsequently converted to succinyl-coenzyme A (CoA) and acetyl-CoA.
D-Psicose biosynthesisNFUNC_0065D-psicose biosynthesis from D-fructose by D-tagatose 3-epimerase. D-psicose, a kind of rare sugar, exhibits suitable sweetness and dose not contribute to calorie production.
Pyrroloquinoline quinone biosynthesisNFUNC_0020Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide.
Riboflavin biosynthesisNFUNC_0058Biosynthesis of riboflavin (vitamin B2), the universal precursor of flavocoenzymes.
Streptogramin resistanceNFUNC_0027Resistance to streptogramin by acetylation or linearizing the lactone ring of antibiotics.
Streptomycin resistanceNFUNC_0054Resistance to streptomycin by phosphorylation or adenylation of antibiotics.
Sulfonamide resistanceNFUNC_0039Resistance to sulfonamide by mutational changes of the gene for dihydropteroate synthase (DHPS).
Tannin degradationNFUNC_0082Hydrolyzes ester links in hydrolyzable tannin.
Thiocyanate hydrolaseNFUNC_0003Degradation of thiocyanate to carbonyl sulfide and ammonia.
Toluene degradation (conversion into benzoate)NFUNC_0009Degradation toluene into benzoate via benzyl alcohol.
Toluene degradation (conversion into protocatechuate via p-cresol)NFUNC_0007Degradation toluene into protocatechuate via p-cresol.
Trehalose biosynthesis (from D-glucose and ADP-glucose)NFUNC_0032Trehalose biosynthesis pathway using D-glucose and ADP-glucose as starting materials. In some organisms, trehalose has a function in desiccation tolerance.
Trehalose biosynthesis (from maltooligosaccharide)NFUNC_0037Trehalose biosynthesis pathway using maltooligosaccharide as starting material. In some organisms, trehalose has a function in desiccation tolerance.
Trehalose biosynthesis (from maltose)NFUNC_0034Trehalose biosynthesis pathway using maltose as starting material. In some organisms, trehalose has a function in desiccation tolerance.
Trehalose biosynthesis (from NDP-glucose and glucose-6-phosphate)NFUNC_0031Trehalose biosynthesis pathway using NDP-glucose and glucose-6-phosphate as starting materials. In some organisms, trehalose has a function in desiccation tolerance.
Trimethoprim resistanceNFUNC_0040Resistance to trimethoprim by mutational changes of the gene for dihydrofolate reductase.
Tyramine biosynthesisNFUNC_0079Biosynthesis of tyramine by the decarboxylation of tyrosine.
Uptake of osmoprotectantNFUNC_0061Uptake of osmoprotectants, such as glycine betaine, ectoine or proline confer resistance to osmotic stress.
Vancomycin resistance (via D-Ala-D-Lac precursor)NFUNC_0089Resistance to vancomycin is due to the presence of operons that encode enzymes (1) for synthesis of low-affinity precursors, in which the C-terminal D-alanine residue is replaced by D-lactate, thus modifying the vancomyin-binding target; and (2) for elimination of the high-affinity precursors that are normally produced by the host, thus removing the vancomycin-binding target.
Vancomycin resistance (via D-Ala-D-Ser precursor)NFUNC_0090Resistance to vancomycin is due to the presence of operons that encode enzymes (1) for synthesis of low-affinity precursors, in which the C-terminal D-alanine residue is replaced by D-serine, thus modifying the vancomyin-binding target; and (2) for elimination of the high-affinity precursors that are normally produced by the host, thus removing the vancomycin-binding target.
Vitamin B6 biosynthesis (PdxA/PdxJ pathway)NFUNC_0060Biosynthesis of pyridoxine 5'-phosphate, one of the de novo biosynthesis pathway.
Vitamin B6 biosynthesis (PdxS/PdxT pathway)NFUNC_0059Biosynthesis of pyridoxal 5'-phosphate. This pathway corresponds to one of the de novo biosynthesis pathway. The biosynthesis of PLP is performed by a complex reaction: in addition to ammonia transfer PdxS/PdxT catalyzes condensation of two phosphosugars, closure of the pyridine ring, as well as isomerase reactions for its phosphosugar substrates. The complexity of the enzyme correlates well with the strong conservation of the PdxS sequence. Contrary to the alternative PLP biosynthesis pathway (glutamate pathway), this pathway does not require PLP as cofactor in its own synthesis.
Data Download
Rule nameIDProtein nameECGene nameRelated Function
2HMSDNRULE_00602-hydroxymuconic semialdehyde dehydrogenaseEC 1.2.1.-NFUNC_0011
4ODNRULE_00624-oxalocrotonate decarboxylaseEC 4.1.1.77NFUNC_0011
4OTNRULE_00614-oxalocrotonate tautomeraseEC 5.3.2.-NFUNC_0011
AAC3NRULE_0149Aminoglycoside N(3')-acetyltransferaseEC 2.3.1.81aacCNFUNC_0052; NFUNC_0053; NFUNC_0041
AAC6NRULE_0150Aminoglycoside N(6')-acetyltransferaseEC 2.3.1.82aacANFUNC_0052; NFUNC_0041
ACDHNRULE_0065Acetaldehyde dehydrogenaseEC 1.2.1.10NFUNC_0011
AFPNRULE_0089Ice-structuring proteinNFUNC_0019
ALGLNRULE_0226Alginate lyaseEC 4.2.2.3algLNFUNC_0062
ALKBNRULE_0024Alkane 1-monooxygenaseEC 1.14.15.3alkBNFUNC_0008
ALRNRULE_0228Alanine racemaseEC 5.1.1.1alrNFUNC_0063
ALYNRULE_0227Alginate lyasealyNFUNC_0062
AMPHDINRULE_0341GDP-mycosamine glycosyltransferaseNFUNC_0095
AMPHDIINRULE_0342GDP-3-keto-6-deoxy-D-mannose C-3 aminotransferaseNFUNC_0095
ANFDNRULE_0344Nitrogenase iron-iron protein alpha chainEC 1.18.6.1anfDNFUNC_0094
ANFGNRULE_0346Nitrogenase iron-iron protein delta chainEC 1.18.6.1anfGNFUNC_0094
ANFKNRULE_0345Nitrogenase iron-iron protein beta chainEC 1.18.6.1anfKNFUNC_0094
ANT2NRULE_01532''-aminoglycoside nucleotidyltransferaseEC 2.7.7.46aadBNFUNC_0052; NFUNC_0053; NFUNC_0042
ANT3NRULE_0154Streptomycin 3''-adenylyltransferaseEC 2.7.7.47aadA, antNFUNC_0054; NFUNC_0042
ANT4NRULE_0152Kanamycin nucleotidyltransferaseEC 2.7.7.-knt, aadDNFUNC_0052; NFUNC_0042
ANT6NRULE_0151Aminoglycoside 6-adenylyltransferaseEC 2.7.7.-aadKNFUNC_0054; NFUNC_0042
ANTANRULE_0044Anthranilate 1,2-dioxygenase large subunitEC 1.14.12.1antANFUNC_0018
ANTBNRULE_0045Anthranilate 1,2-dioxygenase small subunitEC 1.14.12.1antBNFUNC_0018
ANTCNRULE_0081Anthranilate 1,2-dioxygenase electron transfer componentantCNFUNC_0018
APH3NRULE_0156Aminoglycoside 3'-phosphotransferaseEC 2.7.1.-aphA, aphENFUNC_0043; NFUNC_0054; NFUNC_0052
APH6NRULE_0155Streptomycin 6-kinaseEC 2.7.1.72aphD, sph, strNFUNC_0043; NFUNC_0054
APH7NRULE_0157Hygromycin-B 7''-O-kinaseEC 2.7.1.119hygNFUNC_0043; NFUNC_0055
APPANRULE_0259Periplasmic AppA proteinappANFUNC_0085
ARGINRULE_0239ArginaseEC 3.5.3.1rocFNFUNC_0074
ARNANRULE_0132Bifunctional polymyxin resistance protein ArnAarnANFUNC_0036
ARNBNRULE_0133UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferaseEC 2.6.1.87arnBNFUNC_0036
ARNCNRULE_0134Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferaseEC 2.7.8.30arnCNFUNC_0036
ARNDNRULE_0135Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnDEC 3.5.1.n3arnDNFUNC_0036
ARNENRULE_0136Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnEarnENFUNC_0036
ARNFNRULE_0137Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnFarnFNFUNC_0036
ARNTNRULE_0138Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferaseEC 2.4.2.43arnTNFUNC_0036
ARSANRULE_0014Arsenical pump-driving ATPaseEC 3.6.3.16arsANFUNC_0004
ARSB1NRULE_0015Arsenical pump membrane proteinarsBNFUNC_0004
ARSB2NRULE_0016Arsenite resistance protein ArsBarsBNFUNC_0004
ARSC1NRULE_0017Arsenate reductaseEC 1.20.4.1arsCNFUNC_0004
ARSC2NRULE_0018Arsenate reductaseEC 1.20.4.-arsCNFUNC_0004
ARSC3NRULE_0019Arsenate reductaseEC 1.20.4.1arsCNFUNC_0004
ARSDNRULE_0020Arsenical resistance operon trans-acting repressor ArsDarsDNFUNC_0004
ARSHNRULE_0021ArsH proteinarsHNFUNC_0004
ATDA1NRULE_0240Gamma-glutamylanilide synthetaseNFUNC_0075
ATDA2NRULE_0241Putative gamma-glutamylanilide hydrolaseNFUNC_0075
ATDA3NRULE_0357Aniline dioxygenase large subunitNFUNC_0075
ATDA4NRULE_0358Aniline dioxygenase small subunitNFUNC_0075
AZOBNRULE_0238NAD(P)H azoreductaseEC 1.7.-.-NFUNC_0073
AZORNRULE_0236FMN-dependent NADH-azoreductaseEC 1.7.-.-azoRNFUNC_0073
AZRNRULE_0237NADPH azoreductaseEC 1.7.1.6NFUNC_0073
BADHNRULE_0042Aryl-alcohol dehydrogenaseEC 1.1.1.90NFUNC_0009
BCCTNRULE_0220BCCT family transporterNFUNC_0061
BENANRULE_0046Benzoate 1,2-dioxygenase alpha subunitEC 1.14.12.10benANFUNC_0017
BENBNRULE_0047Benzoate 1,2-dioxygenase beta subunitEC 1.14.12.10benBNFUNC_0017
BENCNRULE_0055Benzoate 1,2-dioxygenase electron transfer componentbenCNFUNC_0017
BENDNRULE_00821,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenaseEC 1.3.1.25benDNFUNC_0017
BETANRULE_0175Choline dehydrogenaseEC 1.1.99.1betANFUNC_0049
BETBNRULE_0177Betaine aldehyde dehydrogenaseEC 1.2.1.8betBNFUNC_0049
BIOANRULE_0183Adenosylmethionine-8-amino-7-oxononanoate aminotransferaseEC 2.6.1.62bioANFUNC_0051
BIOBNRULE_0185Biotin synthaseEC 2.8.1.6bioBNFUNC_0051
BIODNRULE_0184ATP-dependent dethiobiotin synthetase BioDEC 6.3.3.3bioDNFUNC_0051
BIOFNRULE_01828-amino-7-oxononanoate synthaseEC 2.3.1.47bioFNFUNC_0051
BLAANRULE_0122Beta-lactamase class AEC 3.5.2.6blaNFUNC_0047; NFUNC_0033; NFUNC_0046; NFUNC_0048
BLABNRULE_0123Metallo-beta-lactamaseEC 3.5.2.6NFUNC_0047; NFUNC_0033; NFUNC_0046; NFUNC_0048
BLACNRULE_0124Beta-lactamase class CEC 3.5.2.6ampCNFUNC_0033; NFUNC_0048
BLADNRULE_0125Beta-lactamase class DEC 3.5.2.6bla, oxaNFUNC_0047; NFUNC_0033; NFUNC_0046
BLENRULE_0096Bleomycin resistance proteinbleNFUNC_0021
BZDH1NRULE_0043Benzaldehyde dehydrogenaseEC 1.2.1.28NFUNC_0009
BZDH2NRULE_0381NAD(P)-dependent benzaldehyde dehydrogenaseEC 1.2.1.-NFUNC_0009
CAADNRULE_00763-chloroacrylic acid dehalogenaseNFUNC_0012
CAADANRULE_00773-chloroacrylic acid dehalogenase alpha subunitNFUNC_0012
CAADBNRULE_00783-chloroacrylic acid dehalogenase beta subunitNFUNC_0012
CAT1NRULE_0107Chloramphenicol acetyltransferaseEC 2.3.1.28catNFUNC_0025
CAT4NRULE_0108Chloramphenicol acetyltransferaseEC 2.3.1.28catNFUNC_0025
CATANRULE_0052Catechol 1,2-dioxygenaseEC 1.13.11.1catANFUNC_0013
CATB1NRULE_0386Muconate cycloisomeraseEC 5.5.1.1catBNFUNC_0013
CATB2NRULE_0053(Chloro)muconate cycloisomeraseEC 5.5.1.-catBNFUNC_0013; NFUNC_0104
CATCNRULE_0054Muconolactone isomeraseEC 5.3.3.4catCNFUNC_0013
CDDHNRULE_0056Cis-dihydrodiol dehydrogenaseEC 1.3.1.-NFUNC_0067; NFUNC_0016
CGTNRULE_0243Cyclomaltodextrin glucanotransferaseEC 2.4.1.19cgtNFUNC_0076
CHOXNRULE_0178Choline oxidaseEC 1.1.3.17NFUNC_0049
CLCANRULE_0382Chlorocatechol 1,2-dioxygenaseEC 1.13.11.-clcANFUNC_0104
CLCBNRULE_0387Chloromuconate cycloisomeraseEC 5.5.1.7clcBNFUNC_0104
CLCDNRULE_0383Dienelactone hydrolaseEC 3.1.1.45clcDNFUNC_0104
CLCENRULE_0384Maleylacetate reductaseEC 1.3.1.32clcENFUNC_0104
CLCFNRULE_0385Chloromuconolactone dehalogenaseclcFNFUNC_0104
COBWNRULE_0007CobW/P47K family proteinNFUNC_0002
CUERNRULE_0328Copper-responsive transcriptional regulator CueRcueRNFUNC_0105
CYP153NRULE_0041Cytochrome P450 CYP153NFUNC_0008
DEHNRULE_0075Haloacetate dehalogenaseEC 3.8.1.3NFUNC_0010
DFR2NRULE_0148Dihydrofolate reductase type 2EC 1.5.1.3NFUNC_0044; NFUNC_0040
DHAANRULE_0050Haloalkane dehalogenaseEC 3.8.1.5NFUNC_0010; NFUNC_0012
DHDRNRULE_0253Dihydrodaidzein reductaseNFUNC_0081
DHPSNRULE_0144Dihydropteroate synthaseEC 2.5.1.15folPNFUNC_0044
DSZANRULE_0103Dibenzothiophene-5,5-dioxide monooxygenaseEC 1.14.13.-dszANFUNC_0029
DSZBNRULE_01042'-hydroxybiphenyl-2-sulfinate desulfinaseEC 3.13.1.3dszBNFUNC_0029
DSZCNRULE_0105Dibenzothiophene monooxygenaseEC 1.14.13.-dszCNFUNC_0029
DTENRULE_0230D-tagatose 3-epimeraseEC 5.3.1.-NFUNC_0065
DZNRNRULE_0252Daidzein reductaseNFUNC_0081
ECTANRULE_0187L-2,4-diaminobutyric acid acetyltransferaseEC 2.3.1.178ectANFUNC_0057; NFUNC_0056
ECTBNRULE_0186Diaminobutyrate--2-oxoglutarate transaminaseEC 2.6.1.76ectBNFUNC_0057; NFUNC_0056
ECTCNRULE_0188L-ectoine synthaseEC 4.2.1.108ectCNFUNC_0057; NFUNC_0056
ECTDNRULE_0189Ectoine hydroxylaseEC 1.17.-.-ectDNFUNC_0057
EDIONRULE_0058extradiol dioxygenaseEC 1.13.11.-NFUNC_0067; NFUNC_0011
EHUANRULE_0219Ectoine ABC transporter ATP-binding proteinehuANFUNC_0061
EHUBNRULE_0216Ectoine ABC transporter substrate-binding proteinehuBNFUNC_0061
EHUCNRULE_0217Ectoine ABC transporter permease proteinehuCNFUNC_0061
EHUDNRULE_0218Ectoine ABC transporter permease proteinehuDNFUNC_0061
ENGBFNRULE_0257Endo-alpha-N-acetylgalactosaminidaseEC 3.2.1.97engBFNFUNC_0084
EPDNRULE_0208D-erythrose-4-phosphate dehydrogenaseEC 1.2.1.72epdNFUNC_0060
ERENRULE_0168Erythromycin esteraseEC 3.1.1.-ereNFUNC_0045
ERMNRULE_0164rRNA adenine N-6-methyltransferaseEC 2.1.1.184ermNFUNC_0045
FADR1NRULE_0101NADH-dependent flavin reductaseEC 1.5.1.-NFUNC_0029; NFUNC_0068; NFUNC_0028
FDR1NRULE_0032Oxygenase electron transfer componentNFUNC_0017; NFUNC_0075; NFUNC_0008; NFUNC_0007; NFUNC_0018; NFUNC_0067; NFUNC_0016; NFUNC_0028
FDR2NRULE_0057Ferredoxin reductaseEC 1.18.1.3NFUNC_0017; NFUNC_0075; NFUNC_0018; NFUNC_0067; NFUNC_0016; NFUNC_0028
FDX1NRULE_0034Putative Rieske-type ferredoxinNFUNC_0017; NFUNC_0075; NFUNC_0008; NFUNC_0007; NFUNC_0018; NFUNC_0067; NFUNC_0016; NFUNC_0028
FOLANRULE_0147Dihydrofolate reductaseEC 1.5.1.3folANFUNC_0044
FOLBNRULE_0158Dihydroneopterin aldolaseEC 4.1.2.25folBNFUNC_0044
FOLCNRULE_0160Bifunctional protein FolCfolCNFUNC_0044
FOLKNRULE_01592-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinaseEC 2.7.6.3folKNFUNC_0044
FOLMNRULE_0146Dihydrofolate reductase FolMEC 1.5.1.3folMNFUNC_0044
FOSANRULE_0098Glutathione transferase FosAEC 2.5.1.18fosANFUNC_0023
FOSBNRULE_0099Metallothiol transferase FosBEC 2.5.1.-fosBNFUNC_0023
FOSXNRULE_0100Fosfomycin resistance protein FosXfosXNFUNC_0023
GADNRULE_0231Glutamate decarboxylaseEC 4.1.1.15NFUNC_0066; NFUNC_0071
GADCNRULE_0234Glutamate/gamma-aminobutyrate antiportergadCNFUNC_0071
GALENRULE_0111UDP-glucose 4-epimeraseEC 5.1.3.2galENFUNC_0083; NFUNC_0026
GALTNRULE_0110Galactose-1-phosphate uridylyltransferaseEC 2.7.7.12galTNFUNC_0083; NFUNC_0026
GBSBNRULE_0176Alcohol dehydrogenaseEC 1.1.1.1gbsBNFUNC_0049
GLATNRULE_0142Glutamine amidotransferaseNFUNC_0044; NFUNC_0038
GLGXNRULE_0139Glycogen debranching enzymeEC 3.2.1.-glgXNFUNC_0037
GMDNRULE_0343GDP-mannose 4,6-dehydrataseEC 4.2.1.47gmdNFUNC_0095
GSDMTNRULE_0181Glycine/sarcosine/dimethylglycine N-methyltransferaseEC 2.1.1.156
EC 2.1.1.157
NFUNC_0050
GSMTNRULE_0179Glycine/sarcosine N-methyltransferaseEC 2.1.1.156NFUNC_0050
HADNRULE_0051(S)-2-haloacid dehalogenaseEC 3.8.1.2NFUNC_0010
HASNRULE_0229Hyaluronan synthaseEC 2.4.1.212hasANFUNC_0064
HDCNRULE_0245Histidine decarboxylaseEC 4.1.1.22hdcNFUNC_0078
HDCANRULE_0244Histidine decarboxylase proenzymeEC 4.1.1.22hdcA, hdcNFUNC_0078
HDCBNRULE_0247HdcB proteinhdcBNFUNC_0078
HDCPNRULE_0246Histidine/histamine antiporterhdcP, hdcTNFUNC_0078
HOANRULE_00644-hydroxy-2-oxovalerate aldolaseEC 4.1.3.39NFUNC_0011
HPAB1NRULE_00854-hydroxyphenylacetate 3-monooxygenase oxygenase componentEC 1.14.14.9hpaBNFUNC_0068
HPAB2NRULE_00864-hydroxyphenylacetate 3-monooxygenase oxygenase componentEC 1.14.14.9hpaBNFUNC_0068
HPACNRULE_01024-hydroxyphenylacetate 3-monooxygenase reductase componentEC 1.5.1.36hpaCNFUNC_0068
HPAD1NRULE_0193Homoprotocatechuate 2,3-dioxygenaseEC 1.13.11.15hpaD, hpcBNFUNC_0068
HPAD2NRULE_0194Homoprotocatechuate 2,3-dioxygenaseEC 1.13.11.15hpaD, hpcBNFUNC_0068
HPAENRULE_01955-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenaseEC 1.2.1.60hpaE, hpcCNFUNC_0068
HPAFNRULE_01965-carboxymethyl-2-hydroxymuconate Delta-isomeraseEC 5.3.3.10hpaF, hpcDNFUNC_0068
HPAGNRULE_01975-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase/2-hydroxyhepta-2,4-diene-1,7-dioate Delta-isomeraseEC 4.1.1.68
EC 5.3.3.-
hpaG, hpcENFUNC_0068
HPAHNRULE_01982-oxo-hepta-3-ene-1,7-dioate hydrataseEC 4.2.-.-hpaH, hpcGNFUNC_0068
HPAINRULE_01992,4-dihydroxyhept-2-ene-1,7-dioate aldolaseEC 4.1.2.-hpcH, hpaINFUNC_0068
HPDHNRULE_00632-hydroxypent-2,4-dienoate hydrataseEC 4.2.-.-NFUNC_0011
HPHNRULE_0174Hygromycin-B 4-O-kinaseEC 2.7.1.163hphNFUNC_0043; NFUNC_0055
HYSANRULE_0232Hyaluronate lyaseEC 4.2.2.1NFUNC_0069
INPNRULE_0106Ice nucleation proteinNFUNC_0024
ISCRNRULE_0332Rrf2 family transcriptional regulator IscRiscRNFUNC_0105
LNBPNRULE_01121,3-beta-galactosyl-N-acetylhexosamine phosphorylaseEC 2.4.1.211NFUNC_0083; NFUNC_0026
LRHINRULE_0242L-rhamnose isomeraseNFUNC_0077
MACANRULE_0166Macrolide-specific efflux protein MacAmacANFUNC_0045
MACBNRULE_0167Macrolide export ATP-binding/permease protein MacBEC 3.6.3.-macBNFUNC_0045
MAPANRULE_0126Maltose phosphorylaseEC 2.4.1.8mapANFUNC_0034
MCPNRULE_0235Milk-clotting proteaseNFUNC_0072
MECANRULE_0129Penicillin-binding protein 2'mecANFUNC_0035
MECINRULE_0131Methicillin resistance regulatory protein MecImecINFUNC_0035
MECRNRULE_0130Methicillin resistance MecR1 proteinmecR1, mecRNFUNC_0035
MERANRULE_0008Mercuric reductaseEC 1.16.1.1merANFUNC_0005
METAHNRULE_0059meta-cleavage compound hydrolaseNFUNC_0011
MGTNRULE_0170Macrolide glycosyltransferaseEC 2.4.1.-mgtNFUNC_0045
MLENRULE_0233Malolactic enzymeNFUNC_0070
MMANRULE_0027Multicomponent monooxygenase alpha subunitEC 1.14.13.-NFUNC_0008; NFUNC_0007; NFUNC_0028
MMBNRULE_0028Multicomponent monooxygenase beta subunitEC 1.14.13.-NFUNC_0008; NFUNC_0007; NFUNC_0028
MMENRULE_0033Multicomponent monooxygenase effector proteinNFUNC_0008; NFUNC_0007; NFUNC_0028
MMG1NRULE_0029Multicomponent monooxygenase gamma subunitNFUNC_0008; NFUNC_0007; NFUNC_0028
MMG2NRULE_0030Multicomponent monooxygenase gamma subunitNFUNC_0008; NFUNC_0007
MMG3NRULE_0031Multicomponent monooxygenase gamma subunitNFUNC_0008; NFUNC_0007
MNTRNRULE_0327DtxR family transcriptional regulator MntRmntRNFUNC_0105
MODANRULE_0324Molybdate ABC transporter substrate-binding proteinmodANFUNC_0105; NFUNC_0097
MODBNRULE_0325Molybdate ABC transporter permease proteinmodBNFUNC_0097
MODCNRULE_0326Molybdate ABC transporter ATP-binding proteinEC 3.6.3.29modCNFUNC_0097
MODENRULE_0323Putative molybdate-dependent transcriptional regulatorNFUNC_0105; NFUNC_0097
MOPNRULE_0322Putative molybdenum-binding proteinNFUNC_0105
MPHNRULE_0169Macrolide 2'-phosphotransferasemphNFUNC_0045
MSADNRULE_0079Malonate semialdehyde decarboxylaseNFUNC_0012
MTRANRULE_0335MtrA/DmsE family decaheme c-type cytochromeNFUNC_0098
MTRBNRULE_0336Outer membrane protein MtrB homologNFUNC_0098
MTRCNRULE_0334OmcA/MtrC family decaheme c-type cytochromeNFUNC_0098
MURF2NRULE_0297UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-lactate ligasemurF2NFUNC_0089
NAGGNRULE_0191Salicylate 5-hydroxylase alpha subunitEC 1.14.13.-nagGNFUNC_0067
NAGHNRULE_0192Salicylate 5-hydroxylase beta subunitEC 1.14.13.-nagHNFUNC_0067
NAHDNRULE_01712-hydroxychromene-2-carboxylate isomerasenahDNFUNC_0067
NAHENRULE_0172Trans-O-hydroxybenzylidenepyruvate hydratase-aldolasenahENFUNC_0067
NAHFNRULE_0173Salicylaldehyde dehydrogenaseEC 1.2.1.65nahFNFUNC_0067
NAHGNRULE_0190Salicylate hydroxylaseEC 1.14.13.1nahGNFUNC_0067
NAHKNRULE_0256N-acetylhexosamine 1-kinaseEC 2.7.1.162nahKNFUNC_0083
NAPCNRULE_0333Multiheme c-type cytochromeNFUNC_0098
NHAANRULE_0001Nitrile hydratase subunit alphaEC 4.2.1.84nthANFUNC_0002
NHABNRULE_0002Nitrile hydratase subunit betaEC 4.2.1.84nthBNFUNC_0002
NIFDNRULE_0347Nitrogenase molybdenum-iron protein alpha chainEC 1.18.6.1nifDNFUNC_0094
NIFKNRULE_0348Nitrogenase molybdenum-iron protein beta chainEC 1.18.6.1nifKNFUNC_0094
NIKRNRULE_0331Nickel-responsive transcriptional regulator NikRnikRNFUNC_0105
OPUAANRULE_0215Osmoprotectant ABC transporter ATP-binding proteinNFUNC_0061
OPUABNRULE_0214Osmoprotectant ABC transporter permease proteinNFUNC_0061
OPUACNRULE_0213Osmoprotectant ABC transporter substrate-binding proteinNFUNC_0061
OPUENRULE_0222Sodium/proline symporterNFUNC_0061
P14KNRULE_0006Nitrile hydratase activator P14KNFUNC_0002
PABBNRULE_0161Para-aminobenzoate synthase component IEC 2.6.1.85pabBNFUNC_0044
PABCNRULE_0162Aminodeoxychorismate lyaseEC 4.1.3.38pabCNFUNC_0044
PANBNRULE_01163-methyl-2-oxobutanoate hydroxymethyltransferaseEC 2.1.2.11panBNFUNC_0030
PANCNRULE_0118Pantothenate synthetaseEC 6.3.2.1panCNFUNC_0030
PANDNRULE_0115Aspartate 1-decarboxylaseEC 4.1.1.11panDNFUNC_0030
PANENRULE_01172-dehydropantoate 2-reductaseEC 1.1.1.169panENFUNC_0030
PCABNRULE_00683-carboxy-cis,cis-muconate cycloisomeraseEC 5.5.1.2pcaBNFUNC_0014
PCACNRULE_00694-carboxymuconolactone decarboxylaseEC 4.1.1.44pcaCNFUNC_0014
PCADNRULE_00703-oxoadipate enol-lactonaseEC 3.1.1.24pcaD, catDNFUNC_0014; NFUNC_0013
PCAFNRULE_0074Beta-ketoadipyl-CoA thiolaseEC 2.3.1.174pcaF, catF, paaJNFUNC_0014; NFUNC_0013; NFUNC_0104
PCAGNRULE_0066Protocatechuate 3,4-dioxygenase alpha subunitEC 1.13.11.3pcaGNFUNC_0014
PCAHNRULE_0067Protocatechuate 3,4-dioxygenase beta subunitEC 1.13.11.3pcaHNFUNC_0014
PCAINRULE_00723-oxoadipate CoA-transferase subunit AEC 2.8.3.6pcaI, catINFUNC_0014; NFUNC_0013; NFUNC_0104
PCAJNRULE_00733-oxoadipate CoA-transferase subunit BEC 2.8.3.6pcaJ, catJNFUNC_0014; NFUNC_0013; NFUNC_0104
PCALNRULE_00713-oxoadipate enol-lactone hydrolase/4-carboxymuconolactone decarboxylaseEC 3.1.1.24
EC 4.1.1.44
pcaLNFUNC_0014; NFUNC_0013
PCHANRULE_0037p-hydroxybenzaldehyde dehydrogenasepchANFUNC_0007
PCHCNRULE_00364-cresol dehydrogenase cytochrome c subunitpchCNFUNC_0007
PCHFNRULE_00354-cresol dehydrogenase flavoprotein subunitEC 1.17.99.1pchFNFUNC_0007
PDXANRULE_02114-hydroxythreonine-4-phosphate dehydrogenaseEC 1.1.1.262pdxANFUNC_0060
PDXBNRULE_0209Erythronate-4-phosphate dehydrogenaseEC 1.1.1.290pdxBNFUNC_0060
PDXJNRULE_0212Pyridoxine 5'-phosphate synthaseEC 2.6.99.2pdxJNFUNC_0060
PDXSNRULE_0206Pyridoxal biosynthesis lyase PdxSEC 4.-.-.-pdxSNFUNC_0059
PDXTNRULE_0207Glutamine amidotransferase subunit PdxTEC 2.6.-.-pdxTNFUNC_0059
PHABNRULE_0011Acetoacetyl-CoA reductaseEC 1.1.1.36NFUNC_0001
PHAC1NRULE_0010Poly(3-hydroxyalkanoate) polymeraseEC 2.3.1.-phaCNFUNC_0001
PHAC2NRULE_0373Poly(3-hydroxyalkanoate) polymerase PhaC subunitEC 2.3.1.-phaCNFUNC_0001
PHAENRULE_0012Poly(3-hydroxyalkanoate) polymerase PhaE subunitEC 2.3.1.-phaENFUNC_0001
PHAFNRULE_0377Phasin PhaFphaFNFUNC_0001
PHAINRULE_0378Phasin PhaIphaINFUNC_0001
PHAP1NRULE_0374PhasinphaPNFUNC_0001
PHAP2NRULE_0375PhasinphaPNFUNC_0001
PHAP3NRULE_0376PhasinphaPNFUNC_0001
PHARNRULE_0013Poly(3-hydroxyalkanoate) polymerase PhaR subunitEC 2.3.1.-phaRNFUNC_0001
PHAYNRULE_0022D-(-)-3-hydroxybutyrate oligomer hydrolaseEC 3.1.1.22NFUNC_0015
PHAZ1NRULE_0023Intracellular poly(3-hydroxyalkanoate) depolymeraseEC 3.1.1.75phaZNFUNC_0015
PHAZ2NRULE_0080Poly(3-hydroxyalkanoate) depolymeraseEC 3.1.1.75phaZNFUNC_0015
PHAZ3NRULE_0088Poly(3-hydroxyalkanoate) depolymeraseEC 3.1.1.-NFUNC_0015
PHEA1NRULE_0083Aromatic ring hydroxylaseEC 1.14.13.-NFUNC_0028
PHEA2NRULE_0084Aromatic ring hydroxylaseEC 1.14.13.-NFUNC_0028
PHYTNRULE_02583-phytaseEC 3.1.3.8phyNFUNC_0085
POBANRULE_0038p-hydroxybenzoate hydroxylaseEC 1.14.13.2pobANFUNC_0007
PQQANRULE_0090Coenzyme PQQ synthesis protein ApqqANFUNC_0020
PQQBNRULE_0091Coenzyme PQQ synthesis protein BpqqBNFUNC_0020
PQQCNRULE_0092Pyrroloquinoline-quinone synthaseEC 1.3.3.11pqqCNFUNC_0020
PQQDNRULE_0093Coenzyme PQQ synthesis protein DpqqDNFUNC_0020
PQQENRULE_0094Coenzyme PQQ synthesis protein EpqqENFUNC_0020
PQQFNRULE_0095Coenzyme PQQ synthesis protein FEC 3.4.24.-pqqFNFUNC_0020
PROPNRULE_0221Osmoprotectant transporterNFUNC_0061
PUEANRULE_0250Polyurethanase ApueANFUNC_0080
PUEBNRULE_0251Polyurethanase BpueBNFUNC_0080
RHDANRULE_0048Ring-hydroxylating dioxygenase alpha subunitEC 1.14.-.-NFUNC_0067; NFUNC_0016
RHDBNRULE_0049Ring-hydroxylating dioxygenase beta subunitEC 1.14.-.-NFUNC_0067; NFUNC_0016
RIBANRULE_0201GTP cyclohydrolase-2EC 3.5.4.25ribANFUNC_0058
RIBBNRULE_02003,4-dihydroxy-2-butanone 4-phosphate synthaseEC 4.1.99.12ribBNFUNC_0058
RIBDNRULE_0202Riboflavin biosynthesis protein RibDribDNFUNC_0058
RIBENRULE_0204Riboflavin synthaseEC 2.5.1.9ribENFUNC_0058
RIBFNRULE_0205Riboflavin biosynthesis protein RibFribFNFUNC_0058
RIBHNRULE_02036,7-dimethyl-8-ribityllumazine synthaseEC 2.5.1.78ribHNFUNC_0058
RLMANRULE_016523S rRNA (guanine-N(1))-methyltransferaseEC 2.1.1.-rlmANFUNC_0045
RUBANRULE_0039RubredoxinrubANFUNC_0008
RUBBNRULE_0040Rubredoxin reductaseEC 1.18.1.1rubBNFUNC_0008
SCNANRULE_0003Thiocyanate hydrolase subunit alphaEC 3.5.5.8scnANFUNC_0003
SCNBNRULE_0004Thiocyanate hydrolase subunit betaEC 3.5.5.8scnBNFUNC_0003
SCNCNRULE_0005Thiocyanate hydrolase subunit gammaEC 3.5.5.8scnCNFUNC_0003
SDMTNRULE_0180Dimethylglycine N-methyltransferaseEC 2.1.1.161NFUNC_0050
SERCNRULE_0210Phosphoserine aminotransferaseEC 2.6.1.52serCNFUNC_0060
SMTANRULE_0009MetallothioneinsmtANFUNC_0006; NFUNC_0105
SOXRNRULE_0329Redox-sensitive transcriptional activator SoxRsoxRNFUNC_0105
SPNRULE_0109Sucrose phosphorylaseEC 2.4.1.7NFUNC_0026
SULNRULE_0145Sulfonamide-resistant dihydropteroate synthaseEC 2.5.1.15sulI, sulII, sulANFUNC_0039
TASENRULE_0255TannaseNFUNC_0082
TEAANRULE_0223TRAP transporter substrate-binding protein TeaAteaANFUNC_0061
TEABNRULE_0224TRAP transporter small transmembrane protein TeaBteaBNFUNC_0061
TEACNRULE_0225TRAP transporter large transmembrane protein TeaCteaCNFUNC_0061
THDRNRULE_0254Tetrahydrodaidzein reductaseNFUNC_0081
TPPNRULE_0120Trehalose-6-phosphate phosphataseEC 3.1.3.12otsBNFUNC_0031
TPSNRULE_0119Trehalose-phosphate synthaseEC 2.4.1.-otsANFUNC_0031
TREPNRULE_0127Alpha,alpha-trehalose phosphorylaseEC 2.4.1.64trePNFUNC_0034
TRESNRULE_0128Trehalose synthaseEC 5.4.99.16treSNFUNC_0034
TRETNRULE_0121Trehalose synthaseEC 2.4.1.245treTNFUNC_0032
TREYNRULE_0140Maltooligosyl trehalose synthaseEC 5.4.99.15treYNFUNC_0037
TREZNRULE_0141Malto-oligosyltrehalose trehalohydrolaseEC 3.2.1.141treZNFUNC_0037
TRPENRULE_0143Anthranilate synthase component IEC 4.1.3.27trpENFUNC_0038
TYRDCNRULE_0248Pyridoxal-dependent tyrosine decarboxylasetyrDC, tdcNFUNC_0079
TYRPNRULE_0249Tyrosine permeasetyrPNFUNC_0079
UPPPNRULE_0097Undecaprenyl-diphosphataseEC 3.6.1.27uppP, bacANFUNC_0022
VANANRULE_0265D-alanine--D-lactate ligaseEC 6.1.2.1NFUNC_0089
VANCNRULE_0268D-alanine--D-serine ligaseEC 6.3.2.-NFUNC_0090
VANGNRULE_0271D-alanine--D-serine ligaseEC 6.3.2.-vanGNFUNC_0090
VANHNRULE_0266D-specific alpha-keto acid dehydrogenaseEC 1.1.1.-vanHNFUNC_0089
VANJNRULE_0295Teicoplanin resistance proteinvanJNFUNC_0089
VANKNRULE_0296Glycyltransferase VanKvanKNFUNC_0089
VANRNRULE_0284Two-component system response regulator VanRvanRNFUNC_0089
VANRANRULE_0279Two-component system response regulator VanRvanRNFUNC_0089
VANRBNRULE_0280Two-component system response regulator VanRvanRBNFUNC_0089
VANRCNRULE_0281Putative two-component system response regulator VanRNFUNC_0090
VANRDNRULE_0282Putative two-component system response regulator VanRNFUNC_0089
VANRGNRULE_0283Putative two-component system response regulator VanRvanRGNFUNC_0090
VANSNRULE_0290Two-component system histidine kinase VanSvanSNFUNC_0089
VANSANRULE_0285Two-component system histidine kinase VanSEC 2.7.13.3vanSNFUNC_0089
VANSBNRULE_0286Two-component system histidine kinase VanSEC 2.7.13.3vanSBNFUNC_0089
VANSCNRULE_0287Putative two-component system histidine kinase VanSvanSNFUNC_0090
VANSDNRULE_0288Putative two-component system histidine kinase VanSvanSDNFUNC_0089
VANSMNRULE_0289Putative two-component system histidine kinase VanSvanSNFUNC_0089
VANTNRULE_0269Serine/alanine racemaseEC 5.1.1.-vanTNFUNC_0090
VANTGNRULE_0272Serine/alanine racemaseEC 5.1.1.-vanTGNFUNC_0090
VANUNRULE_0294Putative transcriptional regulatorvanU, vanUGNFUNC_0090
VANWNRULE_0292Putative vancomycin resistance proteinvanWNFUNC_0089
VANWGNRULE_0293Putative vancomycin resistance proteinvanWGNFUNC_0090
VANXNRULE_0267D-alanyl-D-alanine dipeptidaseEC 3.4.13.22vanXNFUNC_0089
VANXYNRULE_0270D-alanyl-D-alanine dipeptidase/D-alanyl-D-alanine carboxypeptidasevanXYNFUNC_0090
VANXYGNRULE_0273D-alanyl-D-alanine dipeptidasevanXYGNFUNC_0090
VANYNRULE_0277D-alanyl-D-alanine carboxypeptidaseEC 3.4.16.4vanYNFUNC_0089
VANYANRULE_0274D-alanyl-D-alanine carboxypeptidaseEC 3.4.16.4vanYNFUNC_0089
VANYBNRULE_0275D-alanyl-D-alanine carboxypeptidaseEC 3.4.16.4vanYBNFUNC_0089
VANYDNRULE_0276D-alanyl-D-alanine carboxypeptidasevanYDNFUNC_0089
VANYNNRULE_0278D-alanyl-D-alanine dipeptidase/D-alanyl-D-alanine carboxypeptidasevanYnNFUNC_0089
VANZNRULE_0291Teicoplanin resistance proteinvanZNFUNC_0089
VATNRULE_0113Streptogramin A acetyltransferaseEC 2.3.1.-vatDNFUNC_0027
VGBNRULE_0114Virginiamycin B lyaseEC 4.2.99.-vgbNFUNC_0027
VNFDNRULE_0349Nitrogenase vanadium-iron protein alpha chainEC 1.18.6.1vnfDNFUNC_0094
VNFGNRULE_0352Nitrogenase vanadium-iron protein delta chainEC 1.18.6.1vnfGNFUNC_0094
VNFHNRULE_0353Nitrogenase reductaseEC 1.18.6.1vnfHNFUNC_0094
VNFKNRULE_0350Nitrogenase vanadium-iron protein alpha/delta chain EC 1.18.6.1vnfDGNFUNC_0094
VNFKNRULE_0351Nitrogenase vanadium-iron protein beta chainEC 1.18.6.1vnfKNFUNC_0094
XYLANRULE_0025Xylene monooxygenase electron transfer componentEC 1.18.1.3xylANFUNC_0009
XYLMNRULE_0026Xylene monooxygenaseEC 1.14.15.-xylMNFUNC_0009
ZNTRNRULE_0330Zinc-responsive transcriptional regulator ZntRzntRNFUNC_0105