| ID |
NRULE_0022 |
| 遺伝子ID |
PHAY |
| 作成日 |
2012/07/23 |
| タンパク質名 |
Protein name
- Full
- D-(-)-3-hydroxybutyrate oligomer hydrolase
- Short
- 3HB-oligomer hydrolase
- EC
- EC 3.1.1.22
|
| 遺伝子名 |
該当データなし |
| 遺伝子条件 |
HAMAP; MF_01906; hit=1 |
| 参照 |
Gene Ontology
- GO
- GO:0047989, F:hydroxybutyrate-dimer hydrolase activity, IEA:HAMAP
- GO:0019605, P:butyrate metabolic process, IEA:HAMAP
Phylogenomic databases
- KO
- K07518, -
Enzyme and pathway databases
- UniPathway
- UPA00863, -
Family and domain databases
- HAMAP
- MF_01906, 3HBOH, 1, -
- InterPro
- IPR016582, OHBut_olig_hydro_put
- IPR029058, AB_hydrolase
- Pfam
- PF10605, 3HBOH, 1
- PIRSF
- PIRSF011409, HObutyrate_olig_hydrol, 1
|
| 配列の特徴 |
Q0K9H3 Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) Ralstonia eutropha).
| ACT_SITE | 320 | Charge relay system. |
|
| 注釈 |
- Function
- Participates in the degradation of poly-3- hydroxybutyrate (PHB). It works downstream of poly(3- hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers.
- Catalytic activity
- (R)-3-((R)-3-hydroxybutanoyloxy)butanoate + H(2)O = 2 (R)-3-hydroxybutanoate
- Pathway
- Lipid metabolism; butanoate metabolism
- Sequence similarities
- Belongs to the D-(-)-3-hydroxybutyrate oligomer hydrolase family
|
| 参考文献 |
- Q0K9H3 Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) Ralstonia eutropha).
- 16233278
- Cloning of an intracellular D(-)-3-hydroxybutyrate-oligomer hydrolase gene from Ralstonia eutropha H16 and identification of the active site serine residue by site-directed mutagenesis. (J Biosci Bioeng. 2002)
- 12775684
- Purification and properties of an intracellular 3-hydroxybutyrate-oligomer hydrolase (PhaZ2) in Ralstonia eutropha H16 and its identification as a novel intracellular poly(3-hydroxybutyrate) depolymerase. (J Bacteriol. 2003)
- O05690 Ralstonia pickettii (Burkholderia pickettii).
- 8981982
- Purification of an extracellular D-(-)-3-hydroxybutyrate oligomer hydrolase from Pseudomonas sp. strain A1 and cloning and sequencing of its gene. (J Bacteriol. 1997)
|
