| ID |
NRULE_0024 |
| 遺伝子ID |
ALKB |
| 作成日 |
2012/08/06 |
| タンパク質名 |
Protein name
- Full
- Alkane 1-monooxygenase
- EC
- EC 1.14.15.3
Synonym
- Full
- Alkane hydroxylase
|
| 遺伝子名 |
alkB |
| 遺伝子条件 |
BLASTP; P12691; hit=1; score=400; pid=31 |
| 参照 |
Gene Ontology
- GO
- GO:0018685, F:alkane 1-monooxygenase activity, IDA:UniProtKB
- GO:0052869, F:arachidonic acid omega-hydroxylase activity, IEA:EC
- GO:0046872, F:metal ion binding, IEA:UniProtKB-KW
- GO:0043448, P:alkane catabolic process, IDA:UniProtKB
- GO:0006629, P:lipid metabolic process, IEA:InterPro
Phylogenomic databases
- eggNOG
- NOG11338, -
- KO
- K00496, -
Enzyme and pathway databases
- UniPathway
- UPA00191, -
Family and domain databases
- InterPro
- IPR005804, Fatty_acid_desaturase-1
- Pfam
- PF00487, FA_desaturase, 1
|
| 配列の特徴 |
P12691 Pseudomonas oleovorans.
| METAL | 138 | Iron 1. |
| METAL | 142 | Iron 1. |
| METAL | 168 | Iron 1. |
| METAL | 172 | Iron 1. |
| METAL | 173 | Iron 2. |
| METAL | 312 | Iron 2. |
| METAL | 315 | Iron 2. |
| METAL | 316 | Iron 2. |
|
| 注釈 |
- Function
- Catalyzes the hydroxylation of n-alkanes and fatty acids in the presence of a NADH-rubredoxin reductase and rubredoxin
- Catalytic activity
- Octane + reduced rubredoxin + O(2) = 1-octanol + oxidized rubredoxin + H(2)O
- Cofactor
- Binds 2 Fe(3+) ions per subunit
- Pathway
- Hydrocarbon metabolism; alkane degradation
- Subcellular location
- Cell inner membrane; Multi-pass membrane protein
- Sequence similarities
- Belongs to the fatty acid desaturase family. AlkB subfamily
|
| 参考文献 |
- P12691 Pseudomonas oleovorans.
- 7532480
- Genetics of alkane oxidation by Pseudomonas oleovorans. (Biodegradation. 1994)
- Q9I0R2 Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228).
- 14574114
- Functional characterization of genes involved in alkane oxidation by Pseudomonas aeruginosa. (Antonie Van Leeuwenhoek. 2003)
- Q93DN3 Rhodococcus sp. (strain Q15).
- 12450813
- Gene cloning and characterization of multiple alkane hydroxylase systems in Rhodococcus strains Q15 and NRRL B-16531. (Appl Environ Microbiol. 2002)
|
