遺伝子 : Multicomponent monooxygenase gamma subunit (MMG1)

遺伝子情報

ID	NRULE_0029
遺伝子ID	MMG1
作成日	2012/08/17
タンパク質名	Protein name Full Multicomponent monooxygenase gamma subunit
遺伝子名	該当データなし
遺伝子条件	PFAM; PF04663; hit=1
参照	Gene Ontology GO GO:0018662, F:phenol 2-monooxygenase activity, IEA:UniProtKB-EC. GO:0019336, P:phenol-containing compound catabolic process, IEA:UniProtKB-UniPathway. Enzyme and pathway databases UniPathway UPA00728, - Family and domain databases InterPro IPR006756, Phenol_hydroxylase Pfam PF04663, Phenol_monoox, 1
配列の特徴	該当データなし
注釈	Catalytic activity Phenol + NADPH + O(2) = catechol + NADP(+) + H(2)O. Cofactor FAD Fe(2+) Pathway Aromatic compound metabolism; phenol degradation. Subunit structure The multicomponent enzyme phenol hydroxylase comprises three components: oxygenase component (alpha, beta, gamma subunits), electron transfer component (ferredoxin and ferredoxin reductase), and regulatory subunit.
参考文献	P19733 Pseudomonas sp. (strain CF600). 2254258 Complete nucleotide sequence and polypeptide analysis of multicomponent phenol hydroxylase from Pseudomonas sp. strain CF600. (J Bacteriol. 1990) Q84AQ1 Pseudomonas stutzeri (Pseudomonas perfectomarina). 15066815 Phenol hydroxylase and toluene/o-xylene monooxygenase from Pseudomonas stutzeri OX1: interplay between two enzymes. (Appl Environ Microbiol. 2004) Q9ANX1 Burkholderia cepacia (Pseudomonas cepacia). 11751810 Directed evolution of toluene ortho-monooxygenase for enhanced 1-naphthol synthesis and chlorinated ethene degradation. (J Bacteriol. 2002)

関与する機能

機能名
Phenol degradation
Toluene degradation (conversion into protocatechuate via p-cresol)
n-alkane hydroxylation

該当CDS

学名	NBRC番号	CDS	タンパク質名
Brevundimonas diminuta	12697	BDIM_06840	phenol hydroxylase P4 protein
Cupriavidus metallidurans	102507	Rmet_1327	toluene ortho-monooxygenase P4 protein (toluene ortho-monooxygenase P4 component) (protein belongs to CMGI-2)
		Rmet_1783	Phenol hydroxylase P4 protein (Phenol 2-monooxygenase P4 component)
Gordonia amarae	15530	GOAMR_20_01440	putative phenol hydroxylase component
Gordonia sihwensis	108236	GSI01S_09_00240	hypothetical protein
Sphingobium japonicum	101211	SJA_C1-12020	toluene ortho-monooxygenase subunit
Thauera linaloolentis	102519	C666_03855	multi-component phenol hydoxylase subunit gamma LapO
		C666_13590	phenol hydroxylase
Thermomonospora curvata	15933	Tcur_0527	phenol hydroxylase subunit P4