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遺伝子 : Betaine aldehyde dehydrogenase (BETB)

遺伝子情報

ID NRULE_0177
遺伝子ID BETB
作成日 2013/03/27
タンパク質名
Protein name
Full
Betaine aldehyde dehydrogenase
Short
BADH
EC
EC 1.2.1.8
遺伝子名 betB
遺伝子条件 TIGRFAMs; TIGR01804; hit=1
OR
BLASTP; P71016; hit=1; score=1370; pid=52
参照
Gene Ontology
GO
GO:0008802, F:betaine-aldehyde dehydrogenase activity, IDA:EcoCyc
GO:0019285, P:glycine betaine biosynthetic process from choline, IDA:EcoCyc
GO:0006970, P:response to osmotic stress, IEP:EcoCyc
Phylogenomic databases
eggNOG
COG1012, -
HOGENOM
HOG000271505, -
KO
K00130, -
Enzyme and pathway databases
BioCyc
MetaCyc:BADH-MONOMER, -
UniPathway
UPA00529, UER00386
Family and domain databases
HAMAP
MF_00804, BADH, 1, -
InterPro
IPR016160, Ald_DH_CS
IPR015590, Aldehyde_DH_dom
IPR011264, Betaine_Ald_DH
Pfam
PF00171, Aldedh, 1
TIGRFAMs
TIGR01804, BADH, 1
PROSITE
PS00070, ALDEHYDE_DEHYDR_CYS, 1
PS00687, ALDEHYDE_DEHYDR_GLU, 1
配列の特徴
P17445 Escherichia coli (strain K12).
NP_BIND229 - 234NAD (By similarity).
ACT_SITE252By similarity.
ACT_SITE286By similarity.
注釈
Catalytic activity
Betaine aldehyde + NAD(+) + H(2)O = betaine + NADH
Pathway
Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine from betaine aldehyde: step 1/1
Subunit structure
Homotetramer
Sequence similarities
Belongs to the aldehyde dehydrogenase family
参考文献
P17445 Escherichia coli (strain K12).
3512525
Choline-glycine betaine pathway confers a high level of osmotic tolerance in Escherichia coli. (J Bacteriol. 1986)
P71016 Bacillus subtilis (strain 168).
8752328
Synthesis of the osmoprotectant glycine betaine in Bacillus subtilis: characterization of the gbsAB genes. (J Bacteriol. 1996)



関与する機能

機能名
Betaine biosynthesis (from choline)

該当CDS

データダウンロード
学名 NBRC番号 CDS タンパク質名
Acaricomes phytoseiuli107788C501_09370betaine-aldehyde dehydrogenase
Acetobacter aceti14818AaceN1_010100013167betaine aldehyde dehydrogenase
Acinetobacter radioresistens102413ACRAD_02_02360betaine aldehyde dehydrogenase
Acinetobacter sp.100985ACT4_021_00430betaine aldehyde dehydrogenase
Actinopolyspora iraqiensis103187ACTIR_193_00030betaine aldehyde dehydrogenase
ACTIR_664_00140betaine-aldehyde dehydrogenase
Amycolatopsis azurea14573C791_2879Betaine aldehyde dehydrogenase
Amycolatopsis mediterranei13415RAM_13295betaine-aldehyde dehydrogenase
RAM_38835betaine-aldehyde dehydrogenase
Arthrobacter globiformis12137ARGLB_073_00030betaine aldehyde dehydrogenase
Austwickia chelonae105200AUCHE_21_00520putative betaine aldehyde dehydrogenase
Azorhizobium caulinodans14845AZC_1184betaine aldehyde dehydrogenase
Bacillus amyloliquefaciens15535BAMF_2872glycine betaine aldehyde dehydrogenase, NAD+-dependent
Bacillus atrophaeus13721BATRMS_20_00090betaine aldehyde dehydrogenase
Bacillus licheniformis12200BL02564glycine betaine aldehyde dehydrogenase
Bacillus licheniformis12195BLi03270betaine aldehyde dehydrogenase GbsA
Bacillus mojavensis15718GYU_03_00080betaine aldehyde dehydrogenase
Bacillus pumilus12092BAT_0011betaine aldehyde dehydrogenase
Bacillus subtilis3134BSU6633_11410betaine aldehyde dehydrogenase
Bacillus subtilis subsp. subtilis13719BSU31060glycine betaine aldehyde dehydrogenase, NAD+-dependent
Bacillus vallismortis101236BvalD_010100011485betaine aldehyde dehydrogenase
Brevibacterium linens12170BlinB_010200007910putative glycine betaine aldehyde dehydrogenase
Enterobacter aerogenes13534EAE_13520betaine aldehyde dehydrogenase
Enterobacter cloacae subsp. cloacae13535ECL_03122betaine aldehyde dehydrogenase
Enterobacter hormaechei105718HMPREF9086_1259betaine-aldehyde dehydrogenase
Escherichia coli3972EcolC_3311betaine aldehyde dehydrogenase
Escherichia coli13500WFL_01895betaine aldehyde dehydrogenase
Escherichia coli12713Y75_0303betaine aldehyde dehydrogenase, NAD-dependent
Geodermatophilus obscurus13315Gobs_1708Betaine-aldehyde dehydrogenase
Gordonia alkanivorans16433GOALK_050_01170betaine aldehyde dehydrogenase
Gordonia namibiensis108229GONAM_07_01260betaine aldehyde dehydrogenase
Gordonia terrae100016GOTRE_053_00450betaine aldehyde dehydrogenase
Halobacillus halophilus102448HBHAL_1448glycine betaine aldehyde dehydrogenase
Halomonas elongata15536HELO_1860betaine aldehyde dehydrogenase BetB
Kineosphaera limosa100340KILIM_084_00240putative betaine aldehyde dehydrogenase
Klebsiella pneumoniae14438KPR_3974
Klebsiella pneumoniae subsp. rhinoscleromatis105682HMPREF0484_1572betaine-aldehyde dehydrogenase
Kocuria rhizophila103217KRH_18110putative betaine aldehyde dehydrogenase
Labrenzia aggregata16684SIAM614_05115Aldehyde dehydrogenase
Marinomonas mediterranea103028Marme_0468Betaine aldehyde dehydrogenase
Microlunatus phosphovorus101784MLP_20690betaine aldehyde dehydrogenase
Nitriliruptor alkaliphilusNitalDRAFT_0556betaine-aldehyde dehydrogenase
Nocardiopsis dassonvillei14626Ndas_5405Aldehyde Dehydrogenase
Ochrobactrum anthropi15819Oant_2710betaine aldehyde dehydrogenase
Ochrobactrum intermedium15820OINT_1000606betaine aldehyde dehydrogenase
Phaeobacter gallaeciensis16654PGA1_c21670betaine aldehyde dehydrogenase BetB
Propionibacterium acidipropionici12425PACID_07740Betaine aldehyde dehydrogenase
Proteus mirabilis105697HMPREF0693_1035betaine-aldehyde dehydrogenase
Providencia alcalifaciens105687PROVALCAL_00576betaine-aldehyde dehydrogenase
Pseudomonas putida100650PP_5063betaine aldehyde dehydrogenase
Pseudomonas stutzeri14165PSTAB_1639betaine aldehyde dehydrogenase
Rahnella aquatilis105701Rahaq2_1448glycine betaine aldehyde dehydrogenase
Rhizobium etli15573RHE_CH01137betaine aldehyde dehydrogenase (BADH) protein
Rhizobium sp.101917NGR_c07000betaine aldehyde dehydrogenase
Rhizobium tropici15247RTCIAT899_CH04950betaine aldehyde dehydrogenase
Rhodobacter capsulatus16581RCAP_rcc00897betaine-aldehyde dehydrogenase
Rhodobacter sphaeroides12203RSP_2183Betaine aldehyde dehydrogenase
Rhodococcus opacus108011ROP_15570betaine aldehyde dehydrogenase
Roseobacter denitrificans15277RD1_2023betaine aldehyde dehydrogenase
Roseobacter litoralis15278RLO149_c011680betaine aldehyde dehydrogenase BetB
Saccharomonospora azurea14651SacazDRAFT_01026NAD-dependent aldehyde dehydrogenase
SacazDRAFT_01918NAD-dependent aldehyde dehydrogenase
Saccharomonospora cyanea14841SaccyDRAFT_3126NAD-dependent aldehyde dehydrogenase
SaccyDRAFT_4219NAD-dependent aldehyde dehydrogenase
Saccharomonospora glauca14831SacglDRAFT_02635NAD-dependent aldehyde dehydrogenase
SacglDRAFT_03540NAD-dependent aldehyde dehydrogenase
Saccharomonospora viridis12207Svir_23260aldehyde dehydrogenase (acceptor)
Svir_31700aldehyde dehydrogenase (acceptor)
Saccharopolyspora erythraea13426SACE_4203glycine betaine aldehyde dehydrogenase
SACE_5371glycine betaine aldehyde dehydrogenase
Saccharopolyspora spinosa15153SspiN1_010100019536betaine-aldehyde dehydrogenase
Salinispora arenicola105043Q5S_1081_00030betaine aldehyde dehydrogenase
Salinispora tropica105044Strop_1640aldehyde dehydrogenase
Serratia odorifera102598HMPREF0758_4631betaine-aldehyde dehydrogenase
Stackebrandtia nassauensis102104Snas_2393Betaine-aldehyde dehydrogenase
Staphylococcus epidermidis12993SE_2166glycine betaine aldehyde dehydrogenase gbsA
Staphylococcus saprophyticus subsp. saprophyticus102446SSP0195glycine betaine aldehyde dehydrogenase
Starkeya novella14993Snov_3030putative transcriptional regulator, TetR family
Streptomyces avermitilis14893SAV1622putative glycine betaine aldehyde dehydrogenase
SAV3434putative betaine aldehyde dehydrogenase
SAV6948putative betaine aldehyde dehydrogenase
Streptomyces cattleya14057SCAT_3718glycine betaine aldehyde dehydrogenase, NAD+-dependent
Streptomyces clavuligerus13307SCLAV_5680putative glycine betaine aldehyde dehydrogenase
Streptomyces ghanaensis15414SSFG_02796betaine aldehyde dehydrogenase
Streptomyces mobaraensis13819H340_15411putative betaine aldehyde dehydrogenase
Streptomyces sviceus13980SSEG_03367betaine aldehyde dehydrogenase
SSEG_05613betaine aldehyde dehydrogenase
Streptomyces venezuelae13096SVEN_0127Betaine aldehyde dehydrogenase
Tetragenococcus halophilus12172TEH_04590betaine aldehyde dehydrogenase
Vibrio alginolyticus15630N646_4061betaine aldehyde dehydrogenase