| ID |
NRULE_0188 |
| 遺伝子ID |
ECTC |
| 作成日 |
2013/04/09 |
| タンパク質名 |
Protein name
- Full
- L-ectoine synthase
- EC
- EC 4.2.1.108
Synonym
- Full
- N-acetyldiaminobutyrate dehydratase
|
| 遺伝子名 |
ectC |
| 遺伝子条件 |
HAMAP; MF_01255; hit=1 |
| 参照 |
Gene Ontology
- GO
- GO:0033990, F:ectoine synthase activity, IEA:EC
- GO:0019491, P:ectoine biosynthetic process, IEA:HAMAP
Phylogenomic databases
- HOGENOM
- HOG000078059, -
- KO
- K06720, -
Enzyme and pathway databases
- UniPathway
- UPA00067, UER00123
Family and domain databases
- HAMAP
- MF_01255, Ectoine_synth, 1, -
- InterPro
- IPR010462, Ectoine_synth
- Pfam
- PF06339, Ectoine_synth, 1
|
| 配列の特徴 |
該当データなし |
| 注釈 |
- Function
- Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant. Does not act on N-acetylated amino acids like N-alpha-acetyl-L-asparagine,N-alpha-acetyl-L-ornithine, N- alpha-acetyl-L-lysine and N-epsilon-acetyl-L-lysine
- Catalytic activity
- N(4)-acetyl-L-2,4-diaminobutanoate = L-ectoine + H(2)O
- Pathway
- Amine and polyamine biosynthesis; ectoine biosynthesis; L-ectoine from L-aspartate 4-semialdehyde: step 3/3
- Sequence similarities
- Belongs to the ectoine synthase family
|
| 参考文献 |
- O52251 Halomonas elongata (strain ATCC 33173 / DSM 2581 / NBRC 15536 / NCIMB 2198 / 1H9).
- 9864317
- Characterization of biosynthetic enzymes for ectoine as a compatible solute in a moderately halophilic eubacterium, Halomonas elongata. (J Bacteriol. 1999)
|
