| ID |
NRULE_0270 |
| 遺伝子ID |
VANXY |
| 作成日 |
2014/06/26 |
| タンパク質名 |
Protein name
- Full
- D-alanyl-D-alanine dipeptidase/D-alanyl-D-alanine carboxypeptidase
- Short
- D-Ala-D-Ala dipeptidase/D-Ala-D-Ala carboxypeptidase
D,D-dipeptidase/D,D-carboxypeptidase |
| 遺伝子名 |
vanXY |
| 遺伝子条件 |
BLASTP; Q9JN36; hit=1; score=480; pid=45 |
| 参照 |
Gene Ontology
- GO
- GO:0004180, F:carboxypeptidase activity, IEA:UniProtKB-KW
- GO:0046872, F:metal ion binding, IEA:UniProtKB-KW
Enzyme and pathway databases
- BioCyc
- MetaCyc:MONOMER-15477, -
Family and domain databases
- InterPro
- IPR009045, Hedgehog_sig/DD-Pept_Zn-bd_dom
- IPR003709, Pept_M15B/M15C
- Pfam
- PF02557, VanY, 1
|
| 配列の特徴 |
Q9JN36 Enterococcus gallinarum.
| METAL | 95 | Copper; via tele nitrogen. |
| METAL | 95 | Zinc; via tele nitrogen. |
| METAL | 102 | Copper. |
| METAL | 102 | Zinc. |
| METAL | 156 | Copper; via pros nitrogen. |
| METAL | 156 | Zinc; via pros nitrogen. |
| BINDING | 8 | Chloride 1. |
| BINDING | 22 | Chloride 1; via amide nitrogen. |
| BINDING | 22 | Chloride 2; via amide nitrogen. |
| BINDING | 63 | Chloride 4. |
| BINDING | 63 | Sulfate 2. |
| BINDING | 67 | Chloride 3. |
| BINDING | 67 | Chloride 6. |
| BINDING | 69 | Chloride 7. |
| BINDING | 69 | Sulfate 2. |
| BINDING | 88 | Chloride 3; via amide nitrogen. |
| BINDING | 88 | Chloride 6; via amide nitrogen. |
| BINDING | 152 | Sulfate 1; via amide nitrogen. |
|
| 注釈 |
該当データなし |
| 参考文献 |
- Q9JN36 Enterococcus gallinarum.
- 10564477
- Gene vanXYC encodes D,D -dipeptidase (VanX) and D,D-carboxypeptidase (VanY) activities in vancomycin-resistant Enterococcus gallinarum BM4174. (Mol Microbiol. 1999)
- 10817725
- vanC cluster of vancomycin-resistant Enterococcus gallinarum BM4174. (Antimicrob Agents Chemother. 2000)
- 12047383
- Purification and characterization of VanXY(C), a D,D-dipeptidase/D,D-carboxypeptidase in vancomycin-resistant Enterococcus gallinarum BM4174. (Eur J Biochem. 2002)
- 24711382
- Structural basis for the evolution of vancomycin resistance D,D-peptidases. (Proc Natl Acad Sci U S A. 2014)
|
