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Cluster List

Last update : 2013-01-16
[ALL] A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Compound nameorganismactivity
Cluster information CDS ListAclacinomycin AStreptomyces galilaeus ATCC 31615Antitumor; Toxic
Cluster information CDS ListActinorhodinStreptomyces coelicolor A3(2) (=NBRC 15146)Antibacterial
Cluster information CDS ListAlnumycinStreptomyces sp. CM020Antitumor; Gyrase inhibitory; Topoisomerase inhibitory
Cluster information CDS ListAlpha-lipomycinStreptomyces aureofaciens Tü117Antibacterial
Cluster information CDS ListAmphotericin BStreptomyces nodosus ATCC 14899 (=NBRC 12895)Antifungal
Cluster information CDS ListAranciamycinStreptomyces echinatus Tü303Antibacterial; Collagenase inhibitor
Cluster information CDS ListAscomycinStreptomyces hygroscopicus subsp. ascomyceticus ATCC 14891 (=NBRC 13981)Immunosuppressive; Antifungal
Cluster information CDS ListAureothinStreptomyces thioluteus HKI-227 (=NBRC 13341)Antitumor; Antifungal; Insecticidal
Cluster information CDS ListAvermectinStreptomyces avermitilis ATCC 31267 (=NBRC 14893)Anthelmintic
Cluster information CDS ListBenastatinStreptomyces sp. A2991200Antibacterial; Apoptosis inducer; Immunomodulative; glutathione-S-transferase(GST) inhibitor
Cluster information CDS ListBorrelidinStreptomyces parvulus Tü4055Angiogenesis Inhibition; Antibacterial; Antiviral; Antiproliferative
Cluster information CDS ListChalcomycinStreptomyces bikiniensis NRRL 2737Antibacterial
Cluster information CDS ListChartreusinStreptomyces chartreusis HKI-249Antibacterial; Antitumor
Cluster information CDS ListChlorothricinStreptomyces antibioticus DSM 40725Antibacterial
Cluster information CDS ListChromomycinStreptomyces griseus ATCC 13273 (=NBRC 3746)Antibacterial; Antitumor; Antiviral
Cluster information CDS ListConcanamycin AStreptomyces neyagawaensis ATCC 27749 (=NBRC 13477)Antifungal; Antiprotozoal; Antitumor; Antiviral
Cluster information CDS ListCosmomycinStreptomyces olindensis DAUFPE 5622Antitumor
Cluster information CDS ListCryptophycin 1Nostoc sp. ATCC 53789Toxic
Cluster information CDS ListDaunorubicinStreptomyces sp. C5Antitumor
Cluster information CDS ListDoxorubicinStreptomyces peucetius subsp. caesius ATCC 29050 (=NBRC 100596)Antitumor
Cluster information CDS ListElloramycinStreptomyces olivaceus Tü2353Antibacterial; Antitumor
Cluster information CDS ListEnterocinStreptomyces maritimusAntibacterial
Cluster information CDS ListEpothiloneSorangium cellulosum So ce90Antitumor
Cluster information CDS ListFR-008Streptomyces sp. FR-008Antifungal
Cluster information CDS ListFredericamycinStreptomyces griseus ATCC 49344Antibacterial; Antifungal; Antitumor
Cluster information CDS ListFrenolicinStreptomyces roseofulvus AK24158 (=NBRC 15816)Antibacterial; Antiprotozoal
Cluster information CDS ListGilvocarcinStreptomyces griseoflavus Gö 3592Antibacterial; Antitumor; Antiviral
Cluster information CDS ListGranaticinStreptomyces violaceoruber Tü22Antibacterial
Cluster information CDS ListGriseorhodin AStreptomyces sp. JP95Antibacterial; human telomerase inhibitor
Cluster information CDS ListGriseusinStreptomyces griseus K-63Antibacterial
Cluster information CDS ListHalstoctacosanolideStreptomyces halstedii HC34Antibacterial
Cluster information CDS ListHedamycinStreptomyces griseoruber ATCC 15422Antitumor
Cluster information CDS ListHerbimycin AStreptomyces hygroscopicus AM 3672Antitumor
Cluster information CDS ListIndanomycinStreptomyces antibioticus NRRL 8167Antibacterial; Antiprotozoal; Insecticidal; Ionophore
Cluster information CDS ListJadomycin BStreptomyces venezuelae ISP5230 (=NBRC 13096)Antibacterial
Cluster information CDS ListKirromycinStreptomyces collinus Tü365Antibacterial
Cluster information CDS ListLandomycinStreptomyces cyanogenus S136Antitumor
Cluster information CDS ListLasalocidStreptomyces lasaliensis ATCC 31180Antibacterial; Ionophore
Cluster information CDS ListMedermycinStreptomyces sp. AM-7161Antibacterial; Antitumor
Cluster information CDS ListMegalomicinMicromonospora megalomicea subsp. nigra NRRL 3275 (=NBRC 14744)Antibacterial; Antiparasitic; Antiviral
Cluster information CDS ListMeilingmycinStreptomyces nanchangensis NS3226Anthelmintic
Cluster information CDS ListMeridamycinStreptomyces sp. DSM 4137Neuroprotective; Non-immunosuppressive
Cluster information CDS ListMonensinStreptomyces cinnamonensis ATCC 15413Antibacterial; Ionophore; Antiprotozoal
Cluster information CDS ListMycolactoneMycobacterium ulcerans Agy99Toxic; Immunosuppressive
Cluster information CDS ListMyxalamidStigmatella aurantiaca Sga15Antifungal; Antibacterial
Cluster information CDS ListMyxothiazolStigmatella aurantiaca DW4/3-1Antifungal
Cluster information CDS ListNanchangmycinStreptomyces nanchangensis NS3226Antibacterial; Insecticidal; Ionophore
Cluster information CDS ListNiddamycinStreptomyces caelestis NRRL 2821Antibacterial
Cluster information CDS ListNigericinStreptomyces violaceusniger DSM 4137Antibacterial; Ionophore
Cluster information CDS ListNogalamycinStreptomyces nogalater ATCC 27451 (=NBRC 13445)Antibacterial; Antitumor; Toxic
Cluster information CDS ListNystatinStreptomyces noursei ATCC 11455 (=NBRC 14542)Antifungal
Cluster information CDS ListOligomycinStreptomyces avermitilis ATCC 31267 (=NBRC 14893)Antifungal; Toxic
Cluster information CDS ListOviedomycinStreptomyces antibioticus ATCC 11891Antitumor
Cluster information CDS ListOxazolomycinStreptomyces albus JA3453Antibacterial; Antitumor; Antivirus; Ionophore
Cluster information CDS ListPactamycinStreptomyces pactum ATCC 27456 (=NBRC 13433)Antibacterial; Antiprotozoal; Antitumor; Antiviral; Toxic
Cluster information CDS ListPhoslactomycinStreptomyces sp. HK803Antitumor
Cluster information CDS ListPikromycinStreptomyces venezuelae ATCC 15439Antibacterial
Cluster information CDS ListPimaricinStreptomyces natalensis ATCC 27448 (=NBRC 13367)Antifungal
Cluster information CDS ListPladienolideStreptomyces platensis Mer-11107Antitumor
Cluster information CDS ListPolyketomycinStreptomyces diastatochromogenes Tü6028Antibacterial; Antitumor
Cluster information CDS ListPyoluteorinPseudomonas fluorescens Pf-5Antibacterial; Antifungal
Cluster information CDS ListPyrrolomycinActinosporangium vitaminophilum ATCC 31673 (=NBRC 14294)Antibacterial [A, B, C, D, E]; Antifungal [A, B, D]; Immunopotentiator [B]; Toxic [C, D]
Cluster information CDS ListR1128Streptomyces sp. R1128Estrogen receptor antagonist
Cluster information CDS ListRapamycinStreptomyces hygroscopicus NRRL 5491Immunosuppressive; Antitumor; Neuroprotective; Antiaging
Cluster information CDS ListResistomycinStreptomyces resistomycificus HKI-237Antibacterial; Antiviral
Cluster information CDS ListRifamycinAmycolatopsis mediterranei S699 (=NBRC 14843)Antibacterial
Cluster information CDS ListRimocidinStreptomyces diastaticus 108Antifungal
Cluster information CDS ListRubradirinStreptomyces achromogenes var. rubradiris NRRL3061 (=NBRC 14000)Antibacterial
Cluster information CDS ListSch 47554Streptomyces sp. SCC-2136Antifungal
Cluster information CDS ListSoraphenSorangium cellulosum So ce26Antifungal
Cluster information CDS ListSpinosynSaccharopolyspora spinosa NRRL 18538Insecticidal
Cluster information CDS ListSteffimycinStreptomyces steffisburgensis NRRL 3193 (=NBRC 13446)Antitumor
Cluster information CDS ListStigmatellinStigmatella aurantiaca Sga15Antifungal
Cluster information CDS ListStreptolydiginStreptomyces lydicus NRRL 2433 (=NBRC 13058)Antibacterial
Cluster information CDS ListTautomycetinStreptomyces sp. CK4412Antifungal; Antitumor; Immunosuppressive
Cluster information CDS ListTautomycinStreptomyces spiroverticillatusAntibacterial; Antifungal; Antitumor
Cluster information CDS ListTetronomycinStreptomyces sp. NRRL 11266Antibacterial; Ionophore
Cluster information CDS ListUrdamycinStreptomyces fradiae Tü2717Antibacterial; Antitumor
Cluster information CDS ListVicenistatinStreptomyces halstedii HC34Antitumor
Cluster information CDS ListVirginiamycinStreptomyces virginiae MAFF11-0615Antibacterial

close this sectionAbout

Secondary metabolites produced by actinomycetes are important as lead-compounds and/or candidates for drug development. Polyketide synthases (PKSs) and non-ribosomal peptide synthetases (NRPSs) have been attracting much attention for their roles in constructing complex compounds. Secondary metabolite biosynthesis gene clusters are often used in biotechnological applications such as heterologous expression and combinatorial biosynthesis. Many scientific papers are published describing biosynthesis gene clusters every year, but information about a particular gene cluster is often dispersed in many references and is not described in a comprehensive manner.
We constructed a literature-based database about known PKS and NRPS gene clusters. The database consists of biosynthesis cluster information, search menu, retrieve information menu and KS/A domain sequence menu. Our database enables easy access to a comprehensive information related to biosynthesis clusters and browsing standardized up-to-date gene descriptions. Our database will thus serve as a useful reference for the analysis of secondary metabolites. biosynthetic gene clusters.
PubMed 23185043DoBISCUIT: a database of secondary metabolite biosynthetic gene clusters.
Ichikawa, N; Sasagawa, M; Yamamoto, M; Komaki, H; Yoshida, Y; Yamazaki, S and Fujita, N.
Nucleic Acids Research (2013) Database Issue Nucleic Acids Res. 2012 Nov 26.

close this sectionWhat's new

2013-01-16
Release cluster list Release [8]
Benastatin; Chartreusin; Chromomycin; Enterocin; Fredericamycin; Griseorhodin A; Pactamycin; Resistomycin
Update cluster list Update [38]
Aclacinomycin A; Actinorhodin; Alnumycin; Amphotericin B; Aranciamycin; Chalcomycin; Concanamycin A; Cosmomycin; Daunorubicin; Doxorubicin; Elloramycin; FR-008; Frenolicin; Gilvocarcin; Granaticin; Griseusin; Hedamycin; Herbimycin A; Jadomycin B; Landomycin; Medermycin; Megalomicin; Nogalamycin; Nystatin; Oviedomycin; Oxazolomycin; Pikromycin; Pimaricin; Polyketomycin; R1128; Rimocidin; Rubradirin; Sch 47554; Spinosyn; Streptolydigin; Tetronomycin; Urdamycin; Virginiamycin
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