BLAST table : A4092_00200

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function
export
accessionDBtoolalignmentEvalueScoreIdent.linkproductgeneorganismec
1
Q7WZ77_9ACTO
(Q7WZ77)
[query] 1 - 393 (393)
[subject] 1 - 393 (393)
0.0 791   100% Putative OxyA monooxygenase dbv14 Nonomuraea sp. ATCC 39727
2
Q6ZZI8_ACTTI
(Q6ZZI8)
Jump to Teicp2_00270
[query] 3 - 393 (393)
[subject] 1 - 391 (391)
0.0 644   78% OxyA protein
P450 monooxygenase
tcp18 Actinoplanes teichomyceticus
3
E9L1H8_9ZZZZ
(E9L1H8)
[query] 3 - 393 (393)
[subject] 1 - 391 (391)
1e-176 621   76% Putative uncharacterized protein CA37-34 uncultured organism CA37
4
B7T1D4_9BACT
(B7T1D4)
[query] 3 - 393 (393)
[subject] 1 - 391 (391)
1e-175 619   76% Teg9 teg9 uncultured soil bacterium
5
E9L1S3_9ZZZZ
(E9L1S3)
[query] 3 - 393 (393)
[subject] 1 - 391 (391)
1e-171 604   75% Putative uncharacterized protein CA915-31 uncultured organism CA915
6
B7T1C3_9BACT
(B7T1C3)
[query] 15 - 393 (393)
[subject] 3 - 381 (381)
1e-169 599   75% Veg10 veg10 uncultured soil bacterium
7
O87673_9PSEU
(O87673)
Jump to Balhi_00110
[query] 3 - 393 (393)
[subject] 1 - 391 (391)
1e-168 595   73% P450 monooxygenase oxyA Amycolatopsis balhimycina
8
E9L1L3_9ZZZZ
(E9L1L3)
[query] 31 - 393 (393)
[subject] 1 - 363 (363)
1e-167 593   77% Putative uncharacterized protein CA878-14 uncultured organism CA878
9
C5A3_AMYOR
(Q8RN05)
[query] 3 - 393 (393)
[subject] 1 - 391 (391)
1e-167 593   72% Cytochrome P450 165A3
Vancomycin biosynthesis protein OxyA
CYP165A3
oxyA
Amycolatopsis orientalis
Nocardia orientalis
1.14.-.-
10
Q8KLL7_STRTO
(Q8KLL7)
Jump to A4793_00090
[query] 3 - 393 (393)
[subject] 1 - 391 (391)
1e-166 588   71% StaF Streptomyces toyocaensis
11
F8STX6_AMYOR
(F8STX6)
[query] 3 - 393 (393)
[subject] 1 - 391 (391)
1e-166 587   70% p450 monooxygenase vcm5 Amycolatopsis orientalis
Nocardia orientalis
12
O52822_AMYOR
(O52822)
Jump to Chlor_00070
[query] 3 - 393 (393)
[subject] 1 - 391 (391)
1e-164 583   71% PCZA363.6 Amycolatopsis orientalis
Nocardia orientalis
13
Q6ZZI7_ACTTI
(Q6ZZI7)
Jump to Teicp2_00280
[query] 16 - 393 (393)
[subject] 7 - 384 (384)
3e-98 363   48% Oxy protein
P450 monooxygenase
tcp19 Actinoplanes teichomyceticus
14
B7T1D5_9BACT
(B7T1D5)
[query] 16 - 393 (393)
[subject] 7 - 385 (385)
1e-97 361   47% Teg10 teg10 uncultured soil bacterium
15
E9L1L4_9ZZZZ
(E9L1L4)
[query] 16 - 393 (393)
[subject] 7 - 385 (385)
2e-96 357   47% Putative uncharacterized protein CA878-15 uncultured organism CA878
16
E9L1H9_9ZZZZ
(E9L1H9)
[query] 16 - 393 (393)
[subject] 7 - 384 (384)
5e-96 355   47% Putative uncharacterized protein CA37-35 uncultured organism CA37
17
E9L1S4_9ZZZZ
(E9L1S4)
[query] 16 - 393 (393)
[subject] 7 - 384 (384)
9e-95 352   45% Putative uncharacterized protein CA915-32 uncultured organism CA915
18
Q8KLL8_STRTO
(Q8KLL8)
Jump to A4793_00080
[query] 16 - 393 (393)
[subject] 7 - 384 (384)
6e-94 349   45% StaG Streptomyces toyocaensis
19
Q93N82_STRLA
(Q93N82)
[query] 18 - 393 (393)
[subject] 12 - 397 (397)
2e-90 337   47% P450-related oxidase Streptomyces lavendulae
20
Q7WZ78_9ACTO
(Q7WZ78)
Jump to A4092_00190
[query] 16 - 393 (393)
[subject] 7 - 384 (384)
1e-86 325   45% Putative monooxygenase dbv13 Nonomuraea sp. ATCC 39727
21
B7T1D6_9BACT
(B7T1D6)
[query] 18 - 393 (393)
[subject] 13 - 398 (398)
3e-77 293   44% Teg11 teg11 uncultured soil bacterium
22
Q70AY8_ACTTI
(Q70AY8)
Jump to Teicp2_00290
[query] 18 - 393 (393)
[subject] 13 - 398 (398)
1e-76 291   44% OxyB protein tcp20 Actinoplanes teichomyceticus
23
Q8KLL9_STRTO
(Q8KLL9)
Jump to A4793_00070
[query] 18 - 393 (393)
[subject] 13 - 398 (398)
4e-75 286   43% StaH Streptomyces toyocaensis
24
O52823_AMYOR
(O52823)
Jump to Chlor_00080
[query] 12 - 393 (393)
[subject] 14 - 406 (406)
8e-74 282   41% PCZA363.7 Amycolatopsis orientalis
Nocardia orientalis
25
O87674_9PSEU
(O87674)
Jump to Balhi_00120
[query] 12 - 393 (393)
[subject] 6 - 398 (398)
8e-74 282   41% P450 monooxygenase oxyB Amycolatopsis balhimycina
26
Q7WZ79_9ACTO
(Q7WZ79)
Jump to A4092_00180
[query] 18 - 393 (393)
[subject] 13 - 398 (398)
3e-72 277   41% Putative OxyB monooxigenase dbv12 Nonomuraea sp. ATCC 39727
27
E9L1I0_9ZZZZ
(E9L1I0)
[query] 18 - 393 (393)
[subject] 13 - 398 (398)
3e-71 273   42% Putative uncharacterized protein CA37-36 uncultured organism CA37
28
C5B3_AMYOR
(Q8RN04)
[query] 12 - 393 (393)
[subject] 6 - 398 (398)
1e-70 271   41% Cytochrome P450 165B3
Vancomycin biosynthesis protein OxyB
CYP165B3
oxyB
Amycolatopsis orientalis
Nocardia orientalis
1.14.-.-
29
F8STX7_AMYOR
(F8STX7)
[query] 12 - 393 (393)
[subject] 15 - 407 (407)
2e-70 271   40% p450 monooxygenase vcm6 Amycolatopsis orientalis
Nocardia orientalis
30
Q6ZZI6_ACTTI
(Q6ZZI6)
Jump to Teicp_00220
[query] 59 - 393 (393)
[subject] 1 - 348 (348)
9e-70 268   45% P450 monooxygenase Actinoplanes teichomyceticus
31
B7T1C4_9BACT
(B7T1C4)
[query] 52 - 393 (393)
[subject] 1 - 355 (355)
3e-68 263   41% Veg11 veg11 uncultured soil bacterium
32
Q93N81_STRLA
(Q93N81)
[query] 18 - 379 (393)
[subject] 28 - 407 (423)
1e-67 261   40% P450-related oxidase Streptomyces lavendulae
33
E9L1L5_9ZZZZ
(E9L1L5)
[query] 52 - 393 (393)
[subject] 1 - 355 (355)
4e-67 260   43% Putative uncharacterized protein CA878-16 uncultured organism CA878
34
D9WAB6_9ACTO
(D9WAB6)
[query] 18 - 371 (393)
[subject] 139 - 496 (521)
2e-66 258   41% Cytochrome P450 165C4 (Vancomycin biosynthesis protein oxyC) SSOG_04626 Streptomyces himastatinicus ATCC 53653
35
F8STX8_AMYOR
(F8STX8)
[query] 12 - 378 (393)
[subject] 15 - 390 (406)
1e-64 251   38% p450 monooxygenase vcm7 Amycolatopsis orientalis
Nocardia orientalis
36
C7MUK5_SACVD
(C7MUK5)
[query] 18 - 377 (393)
[subject] 24 - 386 (405)
1e-64 251   40% Cytochrome P450 Svir_26970 Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101)
37
E0L281_STRVO
(E0L281)
[query] 18 - 377 (393)
[subject] 43 - 406 (425)
3e-64 250   40% Cytochrome P450 StrviDRAFT_9009 Streptomyces violaceusniger Tu 4113
38
F8JNB7_STRCT
(F8JNB7)
[query] 18 - 379 (393)
[subject] 25 - 389 (406)
5e-64 249   40% Cytochrome P450 SCAT_p0808 Streptomyces cattleya NRRL 8057
39
C5C4_AMYOR
(Q8RN03)
[query] 12 - 378 (393)
[subject] 15 - 390 (406)
4e-63 246   38% Cytochrome P450 165C4
Vancomycin biosynthesis protein OxyC
CYP165C4
oxyC
Amycolatopsis orientalis
Nocardia orientalis
1.14.-.-
40
E9L1S5_9ZZZZ
(E9L1S5)
[query] 18 - 393 (393)
[subject] 13 - 398 (398)
6e-63 246   39% Putative uncharacterized protein CA915-33 uncultured organism CA915
41
O87675_9PSEU
(O87675)
Jump to Balhi_00130
[query] 12 - 378 (393)
[subject] 15 - 390 (406)
4e-62 243   38% P450 monooxygenase oxyC Amycolatopsis balhimycina
42
B7T1C5_9BACT
(B7T1C5)
[query] 12 - 378 (393)
[subject] 38 - 413 (429)
5e-62 243   39% Veg12 veg12 uncultured soil bacterium
43
F8JNA7_STRCT
(F8JNA7)
[query] 9 - 379 (393)
[subject] 15 - 389 (408)
1e-61 241   40% Cytochrome P450 105C1 CYP105C
SCAT_p0798
Streptomyces cattleya NRRL 8057 1.14.-.-
44
E9L1S6_9ZZZZ
(E9L1S6)
[query] 18 - 379 (393)
[subject] 21 - 395 (410)
3e-61 240   35% Putative uncharacterized protein CA915-34 uncultured organism CA915
45
Q6ZZI4_ACTTI
(Q6ZZI4)
Jump to Teicp_00240
[query] 22 - 379 (393)
[subject] 29 - 399 (414)
6e-61 239   37% P450 monooxygenase Actinoplanes teichomyceticus
46
E9L1L7_9ZZZZ
(E9L1L7)
[query] 18 - 379 (393)
[subject] 21 - 395 (410)
6e-61 239   37% Putative uncharacterized protein CA878-18 uncultured organism CA878
47
Q70AY6_ACTTI
(Q70AY6)
Jump to Teicp2_00310
[query] 22 - 379 (393)
[subject] 7 - 377 (392)
6e-61 239   37% OxyC protein tcp22 Actinoplanes teichomyceticus
48
D8I721_AMYMU
(D8I721)
[query] 18 - 377 (393)
[subject] 15 - 377 (396)
1e-60 238   39% Cytochrome P450 AMED_3426 Amycolatopsis mediterranei (strain U-32)
49
Q0RLG3_FRAAA
(Q0RLG3)
[query] 18 - 381 (393)
[subject] 3 - 376 (390)
2e-60 238   39% Cytochrome P450 FAS1 FRAAL2997 Frankia alni (strain ACN14a) 1.14.99.-
50
D9VBX5_9ACTO
(D9VBX5)
[query] 10 - 377 (393)
[subject] 4 - 373 (393)
2e-60 237   39% Cytochrome P450 hydroxylase SSMG_03363 Streptomyces sp. AA4
accessionDBtoolalignmentEvalueScoreIdent.linkinformationpubmed
1
Q7WZ77_9ACTO
(Q7WZ77)
[query] 1 - 393 (393)
[subject] 1 - 393 (393)
0.0 791   100%
Product
Putative OxyA monooxygenase
Gene
dbv14
Organism
Nonomuraea sp. ATCC 39727
1uniprot[Pubmed] 12837387 [Medline] 22721464
The gene cluster for the biosynthesis of the glycopeptide antibiotic A40926 by nonomuraea species.(Chem. Biol.) [2003]
2
Q6ZZI8_ACTTI
(Q6ZZI8)
Jump to Teicp2_00270
[query] 3 - 393 (393)
[subject] 1 - 391 (391)
0.0 644   78%
Product
OxyA protein
P450 monooxygenase
Gene
tcp18
Organism
Actinoplanes teichomyceticus
1uniprot[Pubmed] 15113000
Biosynthetic gene cluster of the glycopeptide antibiotic teicoplanin: characterization of two glycosyltransferases and the key acyltransferase.(Chem. Biol.) [2004]
2uniprot[Pubmed] 14702401
Organization of the teicoplanin gene cluster in Actinoplanes teichomyceticus.(Microbiology) [2004]
[pubmed all]
3
E9L1H8_9ZZZZ
(E9L1H8)
[query] 3 - 393 (393)
[subject] 1 - 391 (391)
1e-176 621   76%
Product
Putative uncharacterized protein
Gene
CA37-34
Organism
uncultured organism CA37
1uniprot[Pubmed] 20945895
Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010]
4
B7T1D4_9BACT
(B7T1D4)
[query] 3 - 393 (393)
[subject] 1 - 391 (391)
1e-175 619   76%
Product
Teg9
Gene
teg9
Organism
uncultured soil bacterium
1uniprot[Pubmed] 18987322
Cloning and characterization of new glycopeptide gene clusters found in an environmental DNA megalibrary.(Proc. Natl. Acad. Sci. U.S.A.) [2008]
5
E9L1S3_9ZZZZ
(E9L1S3)
[query] 3 - 393 (393)
[subject] 1 - 391 (391)
1e-171 604   75%
Product
Putative uncharacterized protein
Gene
CA915-31
Organism
uncultured organism CA915
1uniprot[Pubmed] 20945895
Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010]
6
B7T1C3_9BACT
(B7T1C3)
[query] 15 - 393 (393)
[subject] 3 - 381 (381)
1e-169 599   75%
Product
Veg10
Gene
veg10
Organism
uncultured soil bacterium
1uniprot[Pubmed] 18987322
Cloning and characterization of new glycopeptide gene clusters found in an environmental DNA megalibrary.(Proc. Natl. Acad. Sci. U.S.A.) [2008]
7
O87673_9PSEU
(O87673)
Jump to Balhi_00110
[query] 3 - 393 (393)
[subject] 1 - 391 (391)
1e-168 595   73%
Product
P450 monooxygenase
Gene
oxyA
Organism
Amycolatopsis balhimycina
1uniprot[Pubmed] 10390204 [Medline] 99318579
Identification and analysis of the balhimycin biosynthetic gene cluster and its use for manipulating glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908.(Antimicrob. Agents Chemother.) [1999]
2uniprot[Pubmed] 11932455 [Medline] 21930292
Nonribosomal biosynthesis of vancomycin-type antibiotics: a heptapeptide backbone and eight peptide synthetase modules.(Microbiology) [2002]
3uniprot[Pubmed] 11495926 [Medline] 21486455
A polyketide synthase in glycopeptide biosynthesis: the biosynthesis of the non-proteinogenic amino acid (S)-3,5-dihydroxyphenylglycine.(J. Biol. Chem.) [2001]
4uniprot[Pubmed] 12404385
The biosynthesis of vancomycin-type glycopeptide antibiotics - the order of cyclization steps.(Angew. Chem. Int. Ed. Engl.) [2001]
5uniprot[Pubmed] 11880037 [Medline] 21869276
Glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908: function of a halogenase and a haloperoxidase/perhydrolase.(Chem. Biol.) [2002]
6uniprot
Precursor-directed biosynthesis for the generation of novel glycopetides.(Ernst Schering Res. Found. Workshop) [2005]
[pubmed all]
8
E9L1L3_9ZZZZ
(E9L1L3)
[query] 31 - 393 (393)
[subject] 1 - 363 (363)
1e-167 593   77%
Product
Putative uncharacterized protein
Gene
CA878-14
Organism
uncultured organism CA878
1uniprot[Pubmed] 20945895
Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010]
9
C5A3_AMYOR
(Q8RN05)
[query] 3 - 393 (393)
[subject] 1 - 391 (391)
1e-167 593   72%
Product
Cytochrome P450 165A3
Vancomycin biosynthesis protein OxyA
Gene
CYP165A3
oxyA
Organism
Amycolatopsis orientalis
Nocardia orientalis
1uniprot[Pubmed] 12207020 [Medline] 22344604
Crystal structure of OxyB, a cytochrome P450 implicated in an oxidative phenol coupling reaction during vancomycin biosynthesis.(J. Biol. Chem.) [2002]
10
Q8KLL7_STRTO
(Q8KLL7)
Jump to A4793_00090
[query] 3 - 393 (393)
[subject] 1 - 391 (391)
1e-166 588   71%
Product
StaF
Gene
 
Organism
Streptomyces toyocaensis
1uniprot[Pubmed] 9177243 [Medline] 97322398
D-Ala-D-Ala ligases from glycopeptide antibiotic-producing organisms are highly homologous to the enterococcal vancomycin-resistance ligases VanA and VanB.(Proc. Natl. Acad. Sci. U.S.A.) [1997]
2uniprot[Pubmed] 12060705 [Medline] 22080153
Assembling the glycopeptide antibiotic scaffold: the biosynthesis of A47934 from Streptomyces toyocaensis NRRL15009.(Proc. Natl. Acad. Sci. U.S.A.) [2002]
[pubmed all]
12
O52822_AMYOR
(O52822)
Jump to Chlor_00070
[query] 3 - 393 (393)
[subject] 1 - 391 (391)
1e-164 583   71%
Product
PCZA363.6
Gene
 
Organism
Amycolatopsis orientalis
Nocardia orientalis
1uniprot[Pubmed] 9545426 [Medline] 98212597
Sequencing and analysis of genes involved in the biosynthesis of a vancomycin group antibiotic.(Chem. Biol.) [1998]
13
Q6ZZI7_ACTTI
(Q6ZZI7)
Jump to Teicp2_00280
[query] 16 - 393 (393)
[subject] 7 - 384 (384)
3e-98 363   48%
Product
Oxy protein
P450 monooxygenase
Gene
tcp19
Organism
Actinoplanes teichomyceticus
1uniprot[Pubmed] 15113000
Biosynthetic gene cluster of the glycopeptide antibiotic teicoplanin: characterization of two glycosyltransferases and the key acyltransferase.(Chem. Biol.) [2004]
2uniprot[Pubmed] 20974107
Structural characterization of CYP165D3, a cytochrome P450 involved in phenolic coupling in teicoplanin biosynthesis.(Arch. Biochem. Biophys.) [2011]
3uniprot[Pubmed] 14702401
Organization of the teicoplanin gene cluster in Actinoplanes teichomyceticus.(Microbiology) [2004]
[pubmed all]
14
B7T1D5_9BACT
(B7T1D5)
[query] 16 - 393 (393)
[subject] 7 - 385 (385)
1e-97 361   47%
Product
Teg10
Gene
teg10
Organism
uncultured soil bacterium
1uniprot[Pubmed] 18987322
Cloning and characterization of new glycopeptide gene clusters found in an environmental DNA megalibrary.(Proc. Natl. Acad. Sci. U.S.A.) [2008]
15
E9L1L4_9ZZZZ
(E9L1L4)
[query] 16 - 393 (393)
[subject] 7 - 385 (385)
2e-96 357   47%
Product
Putative uncharacterized protein
Gene
CA878-15
Organism
uncultured organism CA878
1uniprot[Pubmed] 20945895
Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010]
16
E9L1H9_9ZZZZ
(E9L1H9)
[query] 16 - 393 (393)
[subject] 7 - 384 (384)
5e-96 355   47%
Product
Putative uncharacterized protein
Gene
CA37-35
Organism
uncultured organism CA37
1uniprot[Pubmed] 20945895
Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010]
17
E9L1S4_9ZZZZ
(E9L1S4)
[query] 16 - 393 (393)
[subject] 7 - 384 (384)
9e-95 352   45%
Product
Putative uncharacterized protein
Gene
CA915-32
Organism
uncultured organism CA915
1uniprot[Pubmed] 20945895
Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010]
18
Q8KLL8_STRTO
(Q8KLL8)
Jump to A4793_00080
[query] 16 - 393 (393)
[subject] 7 - 384 (384)
6e-94 349   45%
Product
StaG
Gene
 
Organism
Streptomyces toyocaensis
1uniprot[Pubmed] 9177243 [Medline] 97322398
D-Ala-D-Ala ligases from glycopeptide antibiotic-producing organisms are highly homologous to the enterococcal vancomycin-resistance ligases VanA and VanB.(Proc. Natl. Acad. Sci. U.S.A.) [1997]
2uniprot[Pubmed] 12060705 [Medline] 22080153
Assembling the glycopeptide antibiotic scaffold: the biosynthesis of A47934 from Streptomyces toyocaensis NRRL15009.(Proc. Natl. Acad. Sci. U.S.A.) [2002]
[pubmed all]
19
Q93N82_STRLA
(Q93N82)
[query] 18 - 393 (393)
[subject] 12 - 397 (397)
2e-90 337   47%
Product
P450-related oxidase
Gene
 
Organism
Streptomyces lavendulae
1uniprot[Pubmed] 11447274 [Medline] 21353013
Molecular cloning and sequence analysis of the complestatin biosynthetic gene cluster.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
20
Q7WZ78_9ACTO
(Q7WZ78)
Jump to A4092_00190
[query] 16 - 393 (393)
[subject] 7 - 384 (384)
1e-86 325   45%
Product
Putative monooxygenase
Gene
dbv13
Organism
Nonomuraea sp. ATCC 39727
1uniprot[Pubmed] 12837387 [Medline] 22721464
The gene cluster for the biosynthesis of the glycopeptide antibiotic A40926 by nonomuraea species.(Chem. Biol.) [2003]
21
B7T1D6_9BACT
(B7T1D6)
[query] 18 - 393 (393)
[subject] 13 - 398 (398)
3e-77 293   44%
Product
Teg11
Gene
teg11
Organism
uncultured soil bacterium
1uniprot[Pubmed] 18987322
Cloning and characterization of new glycopeptide gene clusters found in an environmental DNA megalibrary.(Proc. Natl. Acad. Sci. U.S.A.) [2008]
22
Q70AY8_ACTTI
(Q70AY8)
Jump to Teicp2_00290
[query] 18 - 393 (393)
[subject] 13 - 398 (398)
1e-76 291   44%
Product
OxyB protein
Gene
tcp20
Organism
Actinoplanes teichomyceticus
1uniprot[Pubmed] 14702401
Organization of the teicoplanin gene cluster in Actinoplanes teichomyceticus.(Microbiology) [2004]
23
Q8KLL9_STRTO
(Q8KLL9)
Jump to A4793_00070
[query] 18 - 393 (393)
[subject] 13 - 398 (398)
4e-75 286   43%
Product
StaH
Gene
 
Organism
Streptomyces toyocaensis
1uniprot[Pubmed] 9177243 [Medline] 97322398
D-Ala-D-Ala ligases from glycopeptide antibiotic-producing organisms are highly homologous to the enterococcal vancomycin-resistance ligases VanA and VanB.(Proc. Natl. Acad. Sci. U.S.A.) [1997]
2uniprot[Pubmed] 12060705 [Medline] 22080153
Assembling the glycopeptide antibiotic scaffold: the biosynthesis of A47934 from Streptomyces toyocaensis NRRL15009.(Proc. Natl. Acad. Sci. U.S.A.) [2002]
[pubmed all]
24
O52823_AMYOR
(O52823)
Jump to Chlor_00080
[query] 12 - 393 (393)
[subject] 14 - 406 (406)
8e-74 282   41%
Product
PCZA363.7
Gene
 
Organism
Amycolatopsis orientalis
Nocardia orientalis
1uniprot[Pubmed] 9545426 [Medline] 98212597
Sequencing and analysis of genes involved in the biosynthesis of a vancomycin group antibiotic.(Chem. Biol.) [1998]
25
O87674_9PSEU
(O87674)
Jump to Balhi_00120
[query] 12 - 393 (393)
[subject] 6 - 398 (398)
8e-74 282   41%
Product
P450 monooxygenase
Gene
oxyB
Organism
Amycolatopsis balhimycina
1uniprot[Pubmed] 10390204 [Medline] 99318579
Identification and analysis of the balhimycin biosynthetic gene cluster and its use for manipulating glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908.(Antimicrob. Agents Chemother.) [1999]
2uniprot[Pubmed] 11932455 [Medline] 21930292
Nonribosomal biosynthesis of vancomycin-type antibiotics: a heptapeptide backbone and eight peptide synthetase modules.(Microbiology) [2002]
3uniprot[Pubmed] 11495926 [Medline] 21486455
A polyketide synthase in glycopeptide biosynthesis: the biosynthesis of the non-proteinogenic amino acid (S)-3,5-dihydroxyphenylglycine.(J. Biol. Chem.) [2001]
4uniprot[Pubmed] 12404385
The biosynthesis of vancomycin-type glycopeptide antibiotics - the order of cyclization steps.(Angew. Chem. Int. Ed. Engl.) [2001]
5uniprot[Pubmed] 11880037 [Medline] 21869276
Glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908: function of a halogenase and a haloperoxidase/perhydrolase.(Chem. Biol.) [2002]
6uniprot
Precursor-directed biosynthesis for the generation of novel glycopetides.(Ernst Schering Res. Found. Workshop) [2005]
[pubmed all]
26
Q7WZ79_9ACTO
(Q7WZ79)
Jump to A4092_00180
[query] 18 - 393 (393)
[subject] 13 - 398 (398)
3e-72 277   41%
Product
Putative OxyB monooxigenase
Gene
dbv12
Organism
Nonomuraea sp. ATCC 39727
1uniprot[Pubmed] 12837387 [Medline] 22721464
The gene cluster for the biosynthesis of the glycopeptide antibiotic A40926 by nonomuraea species.(Chem. Biol.) [2003]
27
E9L1I0_9ZZZZ
(E9L1I0)
[query] 18 - 393 (393)
[subject] 13 - 398 (398)
3e-71 273   42%
Product
Putative uncharacterized protein
Gene
CA37-36
Organism
uncultured organism CA37
1uniprot[Pubmed] 20945895
Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010]
28
C5B3_AMYOR
(Q8RN04)
[query] 12 - 393 (393)
[subject] 6 - 398 (398)
1e-70 271   41%
Product
Cytochrome P450 165B3
Vancomycin biosynthesis protein OxyB
Gene
CYP165B3
oxyB
Organism
Amycolatopsis orientalis
Nocardia orientalis
1uniprot[Pubmed] 12207020 [Medline] 22344604
Crystal structure of OxyB, a cytochrome P450 implicated in an oxidative phenol coupling reaction during vancomycin biosynthesis.(J. Biol. Chem.) [2002]
30
Q6ZZI6_ACTTI
(Q6ZZI6)
Jump to Teicp_00220
[query] 59 - 393 (393)
[subject] 1 - 348 (348)
9e-70 268   45%
Product
P450 monooxygenase
Gene
 
Organism
Actinoplanes teichomyceticus
1uniprot[Pubmed] 15113000
Biosynthetic gene cluster of the glycopeptide antibiotic teicoplanin: characterization of two glycosyltransferases and the key acyltransferase.(Chem. Biol.) [2004]
31
B7T1C4_9BACT
(B7T1C4)
[query] 52 - 393 (393)
[subject] 1 - 355 (355)
3e-68 263   41%
Product
Veg11
Gene
veg11
Organism
uncultured soil bacterium
1uniprot[Pubmed] 18987322
Cloning and characterization of new glycopeptide gene clusters found in an environmental DNA megalibrary.(Proc. Natl. Acad. Sci. U.S.A.) [2008]
32
Q93N81_STRLA
(Q93N81)
[query] 18 - 379 (393)
[subject] 28 - 407 (423)
1e-67 261   40%
Product
P450-related oxidase
Gene
 
Organism
Streptomyces lavendulae
1uniprot[Pubmed] 11447274 [Medline] 21353013
Molecular cloning and sequence analysis of the complestatin biosynthetic gene cluster.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
33
E9L1L5_9ZZZZ
(E9L1L5)
[query] 52 - 393 (393)
[subject] 1 - 355 (355)
4e-67 260   43%
Product
Putative uncharacterized protein
Gene
CA878-16
Organism
uncultured organism CA878
1uniprot[Pubmed] 20945895
Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010]
36
C7MUK5_SACVD
(C7MUK5)
[query] 18 - 377 (393)
[subject] 24 - 386 (405)
1e-64 251   40%
Product
Cytochrome P450
Gene
Svir_26970
Organism
Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101)
1uniprot
Complete genome sequence of Saccharomonospora viridis type strain (P101T).(Stand. Genomic Sci.) [2009]
39
C5C4_AMYOR
(Q8RN03)
[query] 12 - 378 (393)
[subject] 15 - 390 (406)
4e-63 246   38%
Product
Cytochrome P450 165C4
Vancomycin biosynthesis protein OxyC
Gene
CYP165C4
oxyC
Organism
Amycolatopsis orientalis
Nocardia orientalis
1uniprot[Pubmed] 12207020 [Medline] 22344604
Crystal structure of OxyB, a cytochrome P450 implicated in an oxidative phenol coupling reaction during vancomycin biosynthesis.(J. Biol. Chem.) [2002]
2uniprot[Pubmed] 12888556
Crystal structure of OxyC, a cytochrome P450 implicated in an oxidative C-C coupling reaction during vancomycin biosynthesis.(J. Biol. Chem.) [2003]
[pubmed all]
40
E9L1S5_9ZZZZ
(E9L1S5)
[query] 18 - 393 (393)
[subject] 13 - 398 (398)
6e-63 246   39%
Product
Putative uncharacterized protein
Gene
CA915-33
Organism
uncultured organism CA915
1uniprot[Pubmed] 20945895
Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010]
41
O87675_9PSEU
(O87675)
Jump to Balhi_00130
[query] 12 - 378 (393)
[subject] 15 - 390 (406)
4e-62 243   38%
Product
P450 monooxygenase
Gene
oxyC
Organism
Amycolatopsis balhimycina
1uniprot[Pubmed] 10390204 [Medline] 99318579
Identification and analysis of the balhimycin biosynthetic gene cluster and its use for manipulating glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908.(Antimicrob. Agents Chemother.) [1999]
2uniprot[Pubmed] 11932455 [Medline] 21930292
Nonribosomal biosynthesis of vancomycin-type antibiotics: a heptapeptide backbone and eight peptide synthetase modules.(Microbiology) [2002]
3uniprot[Pubmed] 11495926 [Medline] 21486455
A polyketide synthase in glycopeptide biosynthesis: the biosynthesis of the non-proteinogenic amino acid (S)-3,5-dihydroxyphenylglycine.(J. Biol. Chem.) [2001]
4uniprot[Pubmed] 12404385
The biosynthesis of vancomycin-type glycopeptide antibiotics - the order of cyclization steps.(Angew. Chem. Int. Ed. Engl.) [2001]
5uniprot[Pubmed] 11880037 [Medline] 21869276
Glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908: function of a halogenase and a haloperoxidase/perhydrolase.(Chem. Biol.) [2002]
6uniprot
Precursor-directed biosynthesis for the generation of novel glycopetides.(Ernst Schering Res. Found. Workshop) [2005]
[pubmed all]
42
B7T1C5_9BACT
(B7T1C5)
[query] 12 - 378 (393)
[subject] 38 - 413 (429)
5e-62 243   39%
Product
Veg12
Gene
veg12
Organism
uncultured soil bacterium
1uniprot[Pubmed] 18987322
Cloning and characterization of new glycopeptide gene clusters found in an environmental DNA megalibrary.(Proc. Natl. Acad. Sci. U.S.A.) [2008]
44
E9L1S6_9ZZZZ
(E9L1S6)
[query] 18 - 379 (393)
[subject] 21 - 395 (410)
3e-61 240   35%
Product
Putative uncharacterized protein
Gene
CA915-34
Organism
uncultured organism CA915
1uniprot[Pubmed] 20945895
Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010]
45
Q6ZZI4_ACTTI
(Q6ZZI4)
Jump to Teicp_00240
[query] 22 - 379 (393)
[subject] 29 - 399 (414)
6e-61 239   37%
Product
P450 monooxygenase
Gene
 
Organism
Actinoplanes teichomyceticus
1uniprot[Pubmed] 15113000
Biosynthetic gene cluster of the glycopeptide antibiotic teicoplanin: characterization of two glycosyltransferases and the key acyltransferase.(Chem. Biol.) [2004]
46
E9L1L7_9ZZZZ
(E9L1L7)
[query] 18 - 379 (393)
[subject] 21 - 395 (410)
6e-61 239   37%
Product
Putative uncharacterized protein
Gene
CA878-18
Organism
uncultured organism CA878
1uniprot[Pubmed] 20945895
Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010]
47
Q70AY6_ACTTI
(Q70AY6)
Jump to Teicp2_00310
[query] 22 - 379 (393)
[subject] 7 - 377 (392)
6e-61 239   37%
Product
OxyC protein
Gene
tcp22
Organism
Actinoplanes teichomyceticus
1uniprot[Pubmed] 14702401
Organization of the teicoplanin gene cluster in Actinoplanes teichomyceticus.(Microbiology) [2004]
48
D8I721_AMYMU
(D8I721)
[query] 18 - 377 (393)
[subject] 15 - 377 (396)
1e-60 238   39%
Product
Cytochrome P450
Gene
AMED_3426
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
49
Q0RLG3_FRAAA
(Q0RLG3)
[query] 18 - 381 (393)
[subject] 3 - 376 (390)
2e-60 238   39%
Product
Cytochrome P450 FAS1
Gene
FRAAL2997
Organism
Frankia alni (strain ACN14a)
1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]