BLAST table : A4793_00320

DBUniProtKB
check
function
export
accessionDBtoolalignmentEvalueScoreIdent.linkproductgeneorganismec
1
O33806_STRTO
(O33806)
[query] 1 - 346 (346)
[subject] 1 - 346 (346)
0.0 703   100% D-alanine--D-alanine ligase
D-Ala-D-Ala ligase
D-alanylalanine synthetase
DdlM
ddl
Streptomyces toyocaensis 6.3.2.4
2
VANL_STRCO
(Q9XAK7)
[query] 1 - 346 (346)
[subject] 1 - 346 (346)
1e-162 577   79% Putative D-alanine--D-lactate ligase
Vancomycin resistance-like protein
SCO3595
SC66T3.06
Streptomyces coelicolor 6.3.2.-
3
D6EPN3_STRLI
(D6EPN3)
[query] 1 - 346 (346)
[subject] 1 - 346 (346)
1e-162 576   79% D-alanine--D-alanine ligase 1
D-Ala-D-Ala ligase 1
D-alanylalanine synthetase 1
ddl1
SSPG_04065
Streptomyces lividans TK24 6.3.2.4
4
D6TBG9_9CHLR
(D6TBG9)
[query] 1 - 344 (346)
[subject] 1 - 344 (348)
1e-161 571   79% D-alanine--D-alanine ligase 1
D-Ala-D-Ala ligase 1
D-alanylalanine synthetase 1
ddl1
Krac_9315
Ktedonobacter racemifer DSM 44963 6.3.2.4
5
A8L665_FRASN
(A8L665)
[query] 1 - 345 (346)
[subject] 1 - 345 (348)
1e-159 566   78% D-alanine--D-alanine ligase 3
D-Ala-D-Ala ligase 3
D-alanylalanine synthetase 3
ddl3
Franean1_7137
Frankia sp. (strain EAN1pec) 6.3.2.4
6
E9L1P5_9ZZZZ
(E9L1P5)
[query] 1 - 346 (346)
[subject] 1 - 346 (346)
1e-155 553   78% Putative uncharacterized protein CA915-3 uncultured organism CA915
7
E9L1K1_9ZZZZ
(E9L1K1)
[query] 1 - 341 (346)
[subject] 1 - 340 (345)
1e-155 551   77% Putative uncharacterized protein CA878-2 uncultured organism CA878
8
B5I695_9ACTO
(B5I695)
[query] 1 - 346 (346)
[subject] 1 - 346 (346)
1e-153 544   77% D-alanine--D-alanine ligase 2
D-Ala-D-Ala ligase 2
D-alanylalanine synthetase 2
ddl2
SSEG_10121
Streptomyces sviceus ATCC 29083 6.3.2.4
9
Q70B05_ACTTI
(Q70B05)
Jump to Teicp2_00120
[query] 1 - 345 (346)
[subject] 1 - 345 (345)
1e-152 543   77% D-alanine--D-alanine ligase 2
D-Ala-D-Ala ligase 2
D-alanylalanine synthetase 2
tcp3
ddl2
Actinoplanes teichomyceticus 6.3.2.4
10
D2PMX5_KRIFD
(D2PMX5)
[query] 4 - 346 (346)
[subject] 1 - 342 (342)
1e-151 540   78% D-alanine--D-alanine ligase 2
D-Ala-D-Ala ligase 2
D-alanylalanine synthetase 2
ddl2
Kfla_3620
Kribbella flavida (strain DSM 17836 / JCM 10339 / NBRC 14399) 6.3.2.4
11
Q6ZZK2_ACTTI
(Q6ZZK2)
Jump to Teicp_00060
[query] 1 - 345 (346)
[subject] 1 - 345 (345)
1e-151 539   76% D-alanine--D-alanine ligase 1
D-Ala-D-Ala ligase 1
D-alanylalanine synthetase 1
ddl1 Actinoplanes teichomyceticus 6.3.2.4
12
E9L1E9_9ZZZZ
(E9L1E9)
[query] 1 - 346 (346)
[subject] 1 - 345 (345)
1e-151 538   77% Putative uncharacterized protein CA37-5 uncultured organism CA37
13
B8FPP6_DESHD
(B8FPP6)
[query] 1 - 341 (346)
[subject] 1 - 341 (341)
1e-149 531   75% D-alanine--D-alanine ligase 1
D-Ala-D-Ala ligase 1
D-alanylalanine synthetase 1
ddl1
Dhaf_1664
Desulfitobacterium hafniense (strain DCB-2 / DSM 10664) 6.3.2.4
14
C7QDM7_CATAD
(C7QDM7)
[query] 1 - 346 (346)
[subject] 1 - 346 (346)
1e-148 530   72% D-alanine--D-alanine ligase 1
D-Ala-D-Ala ligase 1
D-alanylalanine synthetase 1
ddl1
Caci_5793
Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897) 6.3.2.4
15
D3EYW8_CONWI
(D3EYW8)
[query] 1 - 346 (346)
[subject] 1 - 346 (346)
1e-148 529   74% D-alanine--D-alanine ligase 1
D-Ala-D-Ala ligase 1
D-alanylalanine synthetase 1
ddl1
Cwoe_1414
Conexibacter woesei (strain DSM 14684 / JCM 11494 / NBRC 100937 / ID131577) 6.3.2.4
16
Q24R63_DESHY
(Q24R63)
[query] 1 - 344 (346)
[subject] 1 - 344 (353)
1e-147 527   74% D-alanine--D-alanine ligase 2
D-Ala-D-Ala ligase 2
D-alanylalanine synthetase 2
ddl2
DSY3690
Desulfitobacterium hafniense (strain Y51) 6.3.2.4
17
D9VBI2_9ACTO
(D9VBI2)
[query] 1 - 346 (346)
[subject] 1 - 345 (345)
1e-147 525   73% D-alanine--D-alanine ligase 2
D-Ala-D-Ala ligase 2
D-alanylalanine synthetase 2
ddl2
SSMG_01115
Streptomyces sp. AA4 6.3.2.4
18
Q9S611_AMYOR
(Q9S611)
[query] 1 - 343 (346)
[subject] 1 - 343 (348)
1e-146 521   73% D-alanine--D-alanine ligase
D-Ala-D-Ala ligase
D-alanylalanine synthetase
ddlN
ddl
vanA
Amycolatopsis orientalis
Nocardia orientalis
6.3.2.4
19
D8HIR0_AMYMU
(D8HIR0)
[query] 1 - 346 (346)
[subject] 1 - 342 (342)
1e-144 517   74% D-alanine--D-alanine ligase 2
D-Ala-D-Ala ligase 2
D-alanylalanine synthetase 2
ddlA
ddl2
AMED_8289
Amycolatopsis mediterranei (strain U-32) 6.3.2.4
20
E9UYS7_9ACTO
(E9UYS7)
[query] 1 - 341 (346)
[subject] 1 - 345 (350)
1e-142 508   71% D-alanine--D-alanine ligase
D-Ala-D-Ala ligase
D-alanylalanine synthetase
ddl
NBCG_03948
Nocardioidaceae bacterium Broad-1 6.3.2.4
21
Q6IWG3_9PSEU
(Q6IWG3)
[query] 1 - 341 (346)
[subject] 1 - 342 (347)
1e-141 506   73% D-alanine--D-alanine ligase 2
D-Ala-D-Ala ligase 2
D-alanylalanine synthetase 2
ddlN
ddl2
Amycolatopsis coloradensis 6.3.2.4
22
Q20FL7_9PSEU
(Q20FL7)
[query] 1 - 341 (346)
[subject] 1 - 342 (347)
1e-141 504   73% D-alanine--D-alanine ligase 1
D-Ala-D-Ala ligase 1
D-alanylalanine synthetase 1
ddlN
ddl1
Amycolatopsis coloradensis 6.3.2.4
23
D3PUW5_STANL
(D3PUW5)
[query] 1 - 346 (346)
[subject] 1 - 346 (346)
1e-138 495   68% D-alanine/D-alanine ligase Snas_5356 Stackebrandtia nassauensis (strain DSM 44728 / NRRL B-16338 / NBRC 102104 / LLR-40K-21) 6.3.2.4
24
O52073_PAEPP
(O52073)
[query] 1 - 343 (346)
[subject] 1 - 343 (343)
1e-136 489   64% D-alanine--D-alanine ligase
D-Ala-D-Ala ligase
D-alanylalanine synthetase
vanE
ddl
Paenibacillus popilliae
Bacillus popilliae
6.3.2.4
25
D5US97_TSUPD
(D5US97)
[query] 1 - 343 (346)
[subject] 1 - 342 (344)
1e-133 479   68% D-alanine--D-alanine ligase 1
D-Ala-D-Ala ligase 1
D-alanylalanine synthetase 1
ddl1
Tpau_0523
Tsukamurella paurometabola (strain ATCC 8368 / DSM 20162 / JCM 10117 / NBRC 16120 / NCTC 13040)
Corynebacterium paurometabolum
6.3.2.4
26
Q9EZQ9_ENTFC
(Q9EZQ9)
[query] 1 - 341 (346)
[subject] 1 - 341 (343)
1e-131 471   64% D-alanine--D-alanine ligase 19
D-Ala-D-Ala ligase 19
D-alanylalanine synthetase 19
vanD4
ddl19
vanD
Enterococcus faecium
Streptococcus faecium
6.3.2.4
27
Q6DRQ2_9BACL
(Q6DRQ2)
[query] 1 - 343 (346)
[subject] 1 - 343 (343)
1e-131 471   63% D-alanine--D-alanine ligase
D-Ala-D-Ala ligase
D-alanylalanine synthetase
vanA
ddl
Paenibacillus apiarius 6.3.2.4
28
C4NZP6_ENTFC
(C4NZP6)
[query] 1 - 341 (346)
[subject] 1 - 340 (342)
1e-130 468   65% D-alanine--D-alanine ligase 4
D-Ala-D-Ala ligase 4
D-alanylalanine synthetase 4
vanB
ddl4
Enterococcus faecium
Streptococcus faecium
6.3.2.4
29
Q60FX7_9ENTE
(Q60FX7)
[query] 1 - 341 (346)
[subject] 1 - 341 (343)
1e-130 468   64% D-alanine--D-alanine ligase 3
D-Ala-D-Ala ligase 3
D-alanylalanine synthetase 3
VanD
ddl3
vanD
Enterococcus raffinosus 6.3.2.4
30
Q6DT39_PANTH
(Q6DT39)
[query] 1 - 343 (346)
[subject] 1 - 343 (343)
1e-129 467   62% D-alanine--D-alanine ligase 2
D-Ala-D-Ala ligase 2
D-alanylalanine synthetase 2
vanA
ddl2
Paenibacillus thiaminolyticus
Bacillus thiaminolyticus
6.3.2.4
31
Q7BWD7_STAAU
(Q7BWD7)
[query] 1 - 343 (346)
[subject] 1 - 343 (343)
1e-129 466   64% D-alanine--D-alanine ligase
D-Ala-D-Ala ligase
D-alanylalanine synthetase
vanA
ddl
VRA0040
Staphylococcus aureus 6.3.2.4
32
Q7B608_ENTFC
(Q7B608)
[query] 1 - 343 (346)
[subject] 1 - 343 (343)
1e-129 466   64% D-alanine--D-alanine ligase 14
D-Ala-D-Ala ligase 14
D-alanylalanine synthetase 14
vanA
ddl14
Enterococcus faecium
Streptococcus faecium
6.3.2.4
33
Q0WYK7_ENTFA
(Q0WYK7)
[query] 1 - 343 (346)
[subject] 1 - 343 (343)
1e-129 466   64% D-alanine--D-alanine ligase 5
D-Ala-D-Ala ligase 5
D-alanylalanine synthetase 5
vanA
ddl5
Enterococcus faecalis
Streptococcus faecalis
6.3.2.4
34
D4RFM1_ENTFC
(D4RFM1)
[query] 1 - 343 (346)
[subject] 1 - 343 (343)
1e-129 466   64% D-alanine--D-alanine ligase 1
D-Ala-D-Ala ligase 1
D-alanylalanine synthetase 1
ddl1
EfmE1679_0618
Enterococcus faecium E1679 6.3.2.4
35
D4QQA6_ENTFC
(D4QQA6)
[query] 1 - 343 (346)
[subject] 1 - 343 (343)
1e-129 466   64% D-alanine--D-alanine ligase 1
D-Ala-D-Ala ligase 1
D-alanylalanine synthetase 1
ddl1
EfmE1071_0107
Enterococcus faecium E1071 6.3.2.4
36
C9C611_ENTFC
(C9C611)
[query] 1 - 343 (346)
[subject] 1 - 343 (343)
1e-129 466   64% D-alanine--D-alanine ligase 2
D-Ala-D-Ala ligase 2
D-alanylalanine synthetase 2
ddl2
EFTG_02041
Enterococcus faecium 1,231,410 6.3.2.4
37
C7VPN8_ENTFA
(C7VPN8)
[query] 1 - 343 (346)
[subject] 1 - 343 (343)
1e-129 466   64% D-alanine--D-alanine ligase 2
D-Ala-D-Ala ligase 2
D-alanylalanine synthetase 2
ddl2
EFHG_05029
Enterococcus faecalis HIP11704 6.3.2.4
38
VANA_ENTFC
(P25051)
[query] 1 - 343 (346)
[subject] 1 - 343 (343)
1e-129 466   64% Vancomycin/teicoplanin A-type resistance protein VanA
D-alanine--D-lactate ligase
VanA ligase
vanA Enterococcus faecium
Streptococcus faecium
6.1.2.1
39
C3VIB4_ENTFC
(C3VIB4)
[query] 1 - 343 (346)
[subject] 1 - 343 (343)
1e-129 466   64% D-alanine--D-alanine ligase 2
D-Ala-D-Ala ligase 2
D-alanylalanine synthetase 2
vanA
ddl2
Enterococcus faecium
Streptococcus faecium
6.3.2.4
40
E3USG8_ENTFC
(E3USG8)
[query] 1 - 343 (346)
[subject] 17 - 359 (359)
1e-129 466   64% D-alanine--D-alanine ligase 6
D-Ala-D-Ala ligase 6
D-alanylalanine synthetase 6
ddl6
pLG1-0095
Enterococcus faecium
Streptococcus faecium
6.3.2.4
41
Q5MPR1_9CLOT
(Q5MPR1)
[query] 1 - 341 (346)
[subject] 1 - 340 (342)
1e-129 465   65% D-alanine--D-alanine ligase
D-Ala-D-Ala ligase
D-alanylalanine synthetase
vanB
ddl
Clostridium sp. MLG480 6.3.2.4
42
Q5BP13_PANTH
(Q5BP13)
[query] 1 - 343 (346)
[subject] 1 - 343 (343)
1e-129 465   62% D-alanine--D-alanine ligase 1
D-Ala-D-Ala ligase 1
D-alanylalanine synthetase 1
vanA
ddl1
Paenibacillus thiaminolyticus
Bacillus thiaminolyticus
6.3.2.4
43
Q5MPR3_9CLOT
(Q5MPR3)
[query] 1 - 341 (346)
[subject] 1 - 340 (342)
1e-129 464   65% D-alanine--D-alanine ligase
D-Ala-D-Ala ligase
D-alanylalanine synthetase
vanB
ddl
Clostridium sp. MLG856-1 6.3.2.4
44
Q5MPQ8_9CLOT
(Q5MPQ8)
[query] 1 - 341 (346)
[subject] 1 - 340 (342)
1e-129 464   65% D-alanine--D-alanine ligase
D-Ala-D-Ala ligase
D-alanylalanine synthetase
vanB
ddl
Clostridium sp. MLG392 6.3.2.4
45
Q5MPQ7_9CLOT
(Q5MPQ7)
[query] 1 - 341 (346)
[subject] 1 - 340 (342)
1e-129 464   65% D-alanine--D-alanine ligase
D-Ala-D-Ala ligase
D-alanylalanine synthetase
vanB
ddl
Clostridium sp. MLG661 6.3.2.4
46
Q58F99_ENTFC
(Q58F99)
[query] 1 - 341 (346)
[subject] 1 - 340 (342)
1e-129 464   65% D-alanine--D-alanine ligase 10
D-Ala-D-Ala ligase 10
D-alanylalanine synthetase 10
vanB
ddl10
Enterococcus faecium
Streptococcus faecium
6.3.2.4
47
B6ZHJ4_ENTFA
(B6ZHJ4)
[query] 1 - 341 (346)
[subject] 1 - 340 (342)
1e-129 464   65% D-alanine--D-alanine ligase 4
D-Ala-D-Ala ligase 4
D-alanylalanine synthetase 4
vanB2
ddl4
Enterococcus faecalis
Streptococcus faecalis
6.3.2.4
48
E4JIF3_ENTFC
(E4JIF3)
[query] 1 - 343 (346)
[subject] 1 - 343 (343)
1e-129 464   63% D-alanine--D-alanine ligase 2
D-Ala-D-Ala ligase 2
D-alanylalanine synthetase 2
ddl2
HMPREF9524_01955
Enterococcus faecium TX0133a01 6.3.2.4
49
E4ISK3_ENTFC
(E4ISK3)
[query] 1 - 343 (346)
[subject] 1 - 343 (343)
1e-129 464   63% D-alanine--D-alanine ligase 2
D-Ala-D-Ala ligase 2
D-alanylalanine synthetase 2
ddl2
HMPREF9522_01953
Enterococcus faecium TX0082 6.3.2.4
50
E4IL20_ENTFC
(E4IL20)
[query] 1 - 343 (346)
[subject] 1 - 343 (343)
1e-129 464   63% D-alanine--D-alanine ligase 2
D-Ala-D-Ala ligase 2
D-alanylalanine synthetase 2
ddl2
HMPREF9527_02784
Enterococcus faecium TX0133C 6.3.2.4
accessionDBtoolalignmentEvalueScoreIdent.linkinformationpubmed
1
O33806_STRTO
(O33806)
[query] 1 - 346 (346)
[subject] 1 - 346 (346)
0.0 703   100%
Product
D-alanine--D-alanine ligase
D-Ala-D-Ala ligase
D-alanylalanine synthetase
Gene
DdlM
ddl
Organism
Streptomyces toyocaensis
1uniprot[Pubmed] 9177243 [Medline] 97322398
D-Ala-D-Ala ligases from glycopeptide antibiotic-producing organisms are highly homologous to the enterococcal vancomycin-resistance ligases VanA and VanB.(Proc. Natl. Acad. Sci. U.S.A.) [1997]
2uniprot[Pubmed] 12060705 [Medline] 22080153
Assembling the glycopeptide antibiotic scaffold: the biosynthesis of A47934 from Streptomyces toyocaensis NRRL15009.(Proc. Natl. Acad. Sci. U.S.A.) [2002]
[pubmed all]
2
VANL_STRCO
(Q9XAK7)
[query] 1 - 346 (346)
[subject] 1 - 346 (346)
1e-162 577   79%
Product
Putative D-alanine--D-lactate ligase
Vancomycin resistance-like protein
Gene
SCO3595
SC66T3.06
Organism
Streptomyces coelicolor
1uniprot[Pubmed] 12000953 [Medline] 21996410
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002]
5
A8L665_FRASN
(A8L665)
[query] 1 - 345 (346)
[subject] 1 - 345 (348)
1e-159 566   78%
Product
D-alanine--D-alanine ligase 3
D-Ala-D-Ala ligase 3
D-alanylalanine synthetase 3
Gene
ddl3
Franean1_7137
Organism
Frankia sp. (strain EAN1pec)
1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]
6
E9L1P5_9ZZZZ
(E9L1P5)
[query] 1 - 346 (346)
[subject] 1 - 346 (346)
1e-155 553   78%
Product
Putative uncharacterized protein
Gene
CA915-3
Organism
uncultured organism CA915
1uniprot[Pubmed] 20945895
Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010]
7
E9L1K1_9ZZZZ
(E9L1K1)
[query] 1 - 341 (346)
[subject] 1 - 340 (345)
1e-155 551   77%
Product
Putative uncharacterized protein
Gene
CA878-2
Organism
uncultured organism CA878
1uniprot[Pubmed] 20945895
Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010]
9
Q70B05_ACTTI
(Q70B05)
Jump to Teicp2_00120
[query] 1 - 345 (346)
[subject] 1 - 345 (345)
1e-152 543   77%
Product
D-alanine--D-alanine ligase 2
D-Ala-D-Ala ligase 2
D-alanylalanine synthetase 2
Gene
tcp3
ddl2
Organism
Actinoplanes teichomyceticus
1uniprot[Pubmed] 14702401
Organization of the teicoplanin gene cluster in Actinoplanes teichomyceticus.(Microbiology) [2004]
11
Q6ZZK2_ACTTI
(Q6ZZK2)
Jump to Teicp_00060
[query] 1 - 345 (346)
[subject] 1 - 345 (345)
1e-151 539   76%
Product
D-alanine--D-alanine ligase 1
D-Ala-D-Ala ligase 1
D-alanylalanine synthetase 1
Gene
ddl1
Organism
Actinoplanes teichomyceticus
1uniprot[Pubmed] 15113000
Biosynthetic gene cluster of the glycopeptide antibiotic teicoplanin: characterization of two glycosyltransferases and the key acyltransferase.(Chem. Biol.) [2004]
12
E9L1E9_9ZZZZ
(E9L1E9)
[query] 1 - 346 (346)
[subject] 1 - 345 (345)
1e-151 538   77%
Product
Putative uncharacterized protein
Gene
CA37-5
Organism
uncultured organism CA37
1uniprot[Pubmed] 20945895
Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010]
14
C7QDM7_CATAD
(C7QDM7)
[query] 1 - 346 (346)
[subject] 1 - 346 (346)
1e-148 530   72%
Product
D-alanine--D-alanine ligase 1
D-Ala-D-Ala ligase 1
D-alanylalanine synthetase 1
Gene
ddl1
Caci_5793
Organism
Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
1uniprot
Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).(Stand. Genomic Sci.) [2009]
16
Q24R63_DESHY
(Q24R63)
[query] 1 - 344 (346)
[subject] 1 - 344 (353)
1e-147 527   74%
Product
D-alanine--D-alanine ligase 2
D-Ala-D-Ala ligase 2
D-alanylalanine synthetase 2
Gene
ddl2
DSY3690
Organism
Desulfitobacterium hafniense (strain Y51)
1uniprot[Pubmed] 16513756
Complete genome sequence of the dehalorespiring bacterium Desulfitobacterium hafniense Y51 and comparison with Dehalococcoides ethenogenes 195.(J. Bacteriol.) [2006]
18
Q9S611_AMYOR
(Q9S611)
[query] 1 - 343 (346)
[subject] 1 - 343 (348)
1e-146 521   73%
Product
D-alanine--D-alanine ligase
D-Ala-D-Ala ligase
D-alanylalanine synthetase
Gene
ddlN
ddl
vanA
Organism
Amycolatopsis orientalis
Nocardia orientalis
1uniprot[Pubmed] 9736537 [Medline] 98409705
Glycopeptide antibiotic resistance genes in glycopeptide-producing organisms.(Antimicrob. Agents Chemother.) [1998]
2uniprot[Pubmed] 9177243 [Medline] 97322398
D-Ala-D-Ala ligases from glycopeptide antibiotic-producing organisms are highly homologous to the enterococcal vancomycin-resistance ligases VanA and VanB.(Proc. Natl. Acad. Sci. U.S.A.) [1997]
[pubmed all]
19
D8HIR0_AMYMU
(D8HIR0)
[query] 1 - 346 (346)
[subject] 1 - 342 (342)
1e-144 517   74%
Product
D-alanine--D-alanine ligase 2
D-Ala-D-Ala ligase 2
D-alanylalanine synthetase 2
Gene
ddlA
ddl2
AMED_8289
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
21
Q6IWG3_9PSEU
(Q6IWG3)
[query] 1 - 341 (346)
[subject] 1 - 342 (347)
1e-141 506   73%
Product
D-alanine--D-alanine ligase 2
D-Ala-D-Ala ligase 2
D-alanylalanine synthetase 2
Gene
ddlN
ddl2
Organism
Amycolatopsis coloradensis
1uniprot[Pubmed] 15200859
Antimicrobial resistance gene delivery in animal feeds.(Emerg. Infect. Dis.) [2004]
22
Q20FL7_9PSEU
(Q20FL7)
[query] 1 - 341 (346)
[subject] 1 - 342 (347)
1e-141 504   73%
Product
D-alanine--D-alanine ligase 1
D-Ala-D-Ala ligase 1
D-alanylalanine synthetase 1
Gene
ddlN
ddl1
Organism
Amycolatopsis coloradensis
1uniprot[Pubmed] 16476725
Heterologous expression of glycopeptide resistance vanHAX gene clusters from soil bacteria in Enterococcus faecalis.(J. Antimicrob. Chemother.) [2006]
23
D3PUW5_STANL
(D3PUW5)
[query] 1 - 346 (346)
[subject] 1 - 346 (346)
1e-138 495   68%
Product
D-alanine/D-alanine ligase
Gene
Snas_5356
Organism
Stackebrandtia nassauensis (strain DSM 44728 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)
1uniprot
Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21T).(Stand. Genomic Sci.) [2009]
24
O52073_PAEPP
(O52073)
[query] 1 - 343 (346)
[subject] 1 - 343 (343)
1e-136 489   64%
Product
D-alanine--D-alanine ligase
D-Ala-D-Ala ligase
D-alanylalanine synthetase
Gene
vanE
ddl
Organism
Paenibacillus popilliae
Bacillus popilliae
1uniprot[Pubmed] 10681342 [Medline] 20145393
The biopesticide Paenibacillus popilliae has a vancomycin resistance gene cluster homologous to the enterococcal VanA vancomycin resistance gene cluster.(Antimicrob. Agents Chemother.) [2000]
2uniprot[Pubmed] 15980329
Putative VanRS-like two-component regulatory system associated with the inducible glycopeptide resistance cluster of Paenibacillus popilliae.(Antimicrob. Agents Chemother.) [2005]
[pubmed all]
26
Q9EZQ9_ENTFC
(Q9EZQ9)
[query] 1 - 341 (346)
[subject] 1 - 341 (343)
1e-131 471   64%
Product
D-alanine--D-alanine ligase 19
D-Ala-D-Ala ligase 19
D-alanylalanine synthetase 19
Gene
vanD4
ddl19
vanD
Organism
Enterococcus faecium
Streptococcus faecium
1uniprot[Pubmed] 11083656 [Medline] 20536225
Characterization of a divergent vanD-type resistance element from the first glycopeptide-resistant strain of Enterococcus faecium isolated in Brazil.(Antimicrob. Agents Chemother.) [2000]
2uniprot[Pubmed] 12499162 [Medline] 22386893
VanD-type vancomycin-resistant Enterococcus faecium 10/96A.(Antimicrob. Agents Chemother.) [2003]
[pubmed all]
27
Q6DRQ2_9BACL
(Q6DRQ2)
[query] 1 - 343 (346)
[subject] 1 - 343 (343)
1e-131 471   63%
Product
D-alanine--D-alanine ligase
D-Ala-D-Ala ligase
D-alanylalanine synthetase
Gene
vanA
ddl
Organism
Paenibacillus apiarius
1uniprot[Pubmed] 15561881
Members of the genera Paenibacillus and Rhodococcus harbor genes homologous to enterococcal glycopeptide resistance genes vanA and vanB.(Antimicrob. Agents Chemother.) [2004]
2uniprot[Pubmed] 16189102
Glycopeptide resistance vanA operons in Paenibacillus strains isolated from soil.(Antimicrob. Agents Chemother.) [2005]
[pubmed all]
28
C4NZP6_ENTFC
(C4NZP6)
[query] 1 - 341 (346)
[subject] 1 - 340 (342)
1e-130 468   65%
Product
D-alanine--D-alanine ligase 4
D-Ala-D-Ala ligase 4
D-alanylalanine synthetase 4
Gene
vanB
ddl4
Organism
Enterococcus faecium
Streptococcus faecium
1uniprot[Pubmed] 19273676
VanB-type Enterococcus faecium clinical isolate successively inducibly resistant to, dependent on, and constitutively resistant to vancomycin.(Antimicrob. Agents Chemother.) [2009]
29
Q60FX7_9ENTE
(Q60FX7)
[query] 1 - 341 (346)
[subject] 1 - 341 (343)
1e-130 468   64%
Product
D-alanine--D-alanine ligase 3
D-Ala-D-Ala ligase 3
D-alanylalanine synthetase 3
Gene
VanD
ddl3
vanD
Organism
Enterococcus raffinosus
1uniprot[Pubmed] 17000737
First VanD-Type vancomycin-resistant Enterococcus raffinosus isolate.(Antimicrob. Agents Chemother.) [2006]
30
Q6DT39_PANTH
(Q6DT39)
[query] 1 - 343 (346)
[subject] 1 - 343 (343)
1e-129 467   62%
Product
D-alanine--D-alanine ligase 2
D-Ala-D-Ala ligase 2
D-alanylalanine synthetase 2
Gene
vanA
ddl2
Organism
Paenibacillus thiaminolyticus
Bacillus thiaminolyticus
1uniprot[Pubmed] 15561881
Members of the genera Paenibacillus and Rhodococcus harbor genes homologous to enterococcal glycopeptide resistance genes vanA and vanB.(Antimicrob. Agents Chemother.) [2004]
2uniprot[Pubmed] 16189102
Glycopeptide resistance vanA operons in Paenibacillus strains isolated from soil.(Antimicrob. Agents Chemother.) [2005]
[pubmed all]
31
Q7BWD7_STAAU
(Q7BWD7)
[query] 1 - 343 (346)
[subject] 1 - 343 (343)
1e-129 466   64%
Product
D-alanine--D-alanine ligase
D-Ala-D-Ala ligase
D-alanylalanine synthetase
Gene
vanA
ddl
VRA0040
Organism
Staphylococcus aureus
1uniprot[Pubmed] 14645850
Genetic analysis of a high-level vancomycin-resistant isolate of Staphylococcus aureus.(Science) [2003]
32
Q7B608_ENTFC
(Q7B608)
[query] 1 - 343 (346)
[subject] 1 - 343 (343)
1e-129 466   64%
Product
D-alanine--D-alanine ligase 14
D-Ala-D-Ala ligase 14
D-alanylalanine synthetase 14
Gene
vanA
ddl14
Organism
Enterococcus faecium
Streptococcus faecium
1uniprot[Pubmed] 17116680
Comparative DNA analysis of two vanA plasmids from Enterococcus faecium strains isolated from poultry and a poultry farmer in Norway.(Antimicrob. Agents Chemother.) [2007]
2uniprot[Pubmed] 17951264
Molecular characterization of vancomycin-resistant enterococci in Hangzhou, China.(J. Antimicrob. Chemother.) [2007]
3uniprot[Pubmed] 19846656
Heteroresistance to teicoplanin in Enterococcus faecium harboring the vanA gene.(J. Clin. Microbiol.) [2009]
4uniprot[Pubmed] 18511120
The toxin-antitoxin system w-e-z ensures stable maintenance of vanA plasmids in an antibiotic-free environment.(Plasmid) [2008]
5uniprot
Tn1546 is part of a larger plasmid-encoded genetic unit horizontally disseminated among clonal Enterococcus faecium lineages.(J. Antimicrob. Chemother.) [2010]
[pubmed all]
33
Q0WYK7_ENTFA
(Q0WYK7)
[query] 1 - 343 (346)
[subject] 1 - 343 (343)
1e-129 466   64%
Product
D-alanine--D-alanine ligase 5
D-Ala-D-Ala ligase 5
D-alanylalanine synthetase 5
Gene
vanA
ddl5
Organism
Enterococcus faecalis
Streptococcus faecalis
1uniprot[Pubmed] 17021204
Pheromone-responsive conjugative vancomycin resistance plasmids in Enterococcus faecalis isolates from humans and chicken feces.(Appl. Environ. Microbiol.) [2006]
2uniprot[Pubmed] 20660665
Dissemination of an Enterococcus Inc18-Like vanA plasmid associated with vancomycin-resistant Staphylococcus aureus.(Antimicrob. Agents Chemother.) [2010]
[pubmed all]
34
D4RFM1_ENTFC
(D4RFM1)
[query] 1 - 343 (346)
[subject] 1 - 343 (343)
1e-129 466   64%
Product
D-alanine--D-alanine ligase 1
D-Ala-D-Ala ligase 1
D-alanylalanine synthetase 1
Gene
ddl1
EfmE1679_0618
Organism
Enterococcus faecium E1679
1uniprot[Pubmed] 20398277
Pyrosequencing-based comparative genome analysis of the nosocomial pathogen Enterococcus faecium and identification of a large transferable pathogenicity island.(BMC Genomics) [2010]
35
D4QQA6_ENTFC
(D4QQA6)
[query] 1 - 343 (346)
[subject] 1 - 343 (343)
1e-129 466   64%
Product
D-alanine--D-alanine ligase 1
D-Ala-D-Ala ligase 1
D-alanylalanine synthetase 1
Gene
ddl1
EfmE1071_0107
Organism
Enterococcus faecium E1071
1uniprot[Pubmed] 20398277
Pyrosequencing-based comparative genome analysis of the nosocomial pathogen Enterococcus faecium and identification of a large transferable pathogenicity island.(BMC Genomics) [2010]
38
VANA_ENTFC
(P25051)
[query] 1 - 343 (346)
[subject] 1 - 343 (343)
1e-129 466   64%
Product
Vancomycin/teicoplanin A-type resistance protein VanA
D-alanine--D-lactate ligase
VanA ligase
Gene
vanA
Organism
Enterococcus faecium
Streptococcus faecium
1uniprot[Pubmed] 2266943 [Medline] 91094773
The VANA glycopeptide resistance protein is related to D-alanyl-D-alanine ligase cell wall biosynthesis enzymes.(Mol. Gen. Genet.) [1990]
2uniprot[Pubmed] 8380148 [Medline] 93106944
Characterization of Tn1546, a Tn3-related transposon conferring glycopeptide resistance by synthesis of depsipeptide peptidoglycan precursors in Enterococcus faecium BM4147.(J. Bacteriol.) [1993]
3uniprot[Pubmed] 1931965 [Medline] 92031480
Molecular basis for vancomycin resistance in Enterococcus faecium BM4147: biosynthesis of a depsipeptide peptidoglycan precursor by vancomycin resistance proteins VanH and VanA.(Biochemistry) [1991]
4uniprot[Pubmed] 1522072 [Medline] 92394903
The cytoplasmic peptidoglycan precursor of vancomycin-resistant Enterococcus faecalis terminates in lactate.(J. Bacteriol.) [1992]
5uniprot[Pubmed] 10908650
The molecular basis of vancomycin resistance in clinically relevant Enterococci: crystal structure of D-alanyl-D-lactate ligase (VanA).(Proc. Natl. Acad. Sci. U.S.A.) [2000]
[pubmed all]
40
E3USG8_ENTFC
(E3USG8)
[query] 1 - 343 (346)
[subject] 17 - 359 (359)
1e-129 466   64%
Product
D-alanine--D-alanine ligase 6
D-Ala-D-Ala ligase 6
D-alanylalanine synthetase 6
Gene
ddl6
pLG1-0095
Organism
Enterococcus faecium
Streptococcus faecium
1uniprot[Pubmed] 20951641
A multiresistance megaplasmid pLG1 bearing a hylEfm genomic island in hospital Enterococcus faecium isolates.(Int. J. Med. Microbiol.) [2011]
41
Q5MPR1_9CLOT
(Q5MPR1)
[query] 1 - 341 (346)
[subject] 1 - 340 (342)
1e-129 465   65%
Product
D-alanine--D-alanine ligase
D-Ala-D-Ala ligase
D-alanylalanine synthetase
Gene
vanB
ddl
Organism
Clostridium sp. MLG480
1uniprot[Pubmed] 15616278
Comparison of three PCR primer sets for identification of vanB gene carriage in feces and correlation with carriage of vancomycin-resistant enterococci: interference by vanB-containing anaerobic bacilli.(Antimicrob. Agents Chemother.) [2005]
43
Q5MPR3_9CLOT
(Q5MPR3)
[query] 1 - 341 (346)
[subject] 1 - 340 (342)
1e-129 464   65%
Product
D-alanine--D-alanine ligase
D-Ala-D-Ala ligase
D-alanylalanine synthetase
Gene
vanB
ddl
Organism
Clostridium sp. MLG856-1
1uniprot[Pubmed] 15616278
Comparison of three PCR primer sets for identification of vanB gene carriage in feces and correlation with carriage of vancomycin-resistant enterococci: interference by vanB-containing anaerobic bacilli.(Antimicrob. Agents Chemother.) [2005]
44
Q5MPQ8_9CLOT
(Q5MPQ8)
[query] 1 - 341 (346)
[subject] 1 - 340 (342)
1e-129 464   65%
Product
D-alanine--D-alanine ligase
D-Ala-D-Ala ligase
D-alanylalanine synthetase
Gene
vanB
ddl
Organism
Clostridium sp. MLG392
1uniprot[Pubmed] 15616278
Comparison of three PCR primer sets for identification of vanB gene carriage in feces and correlation with carriage of vancomycin-resistant enterococci: interference by vanB-containing anaerobic bacilli.(Antimicrob. Agents Chemother.) [2005]
45
Q5MPQ7_9CLOT
(Q5MPQ7)
[query] 1 - 341 (346)
[subject] 1 - 340 (342)
1e-129 464   65%
Product
D-alanine--D-alanine ligase
D-Ala-D-Ala ligase
D-alanylalanine synthetase
Gene
vanB
ddl
Organism
Clostridium sp. MLG661
1uniprot[Pubmed] 15616278
Comparison of three PCR primer sets for identification of vanB gene carriage in feces and correlation with carriage of vancomycin-resistant enterococci: interference by vanB-containing anaerobic bacilli.(Antimicrob. Agents Chemother.) [2005]
47
B6ZHJ4_ENTFA
(B6ZHJ4)
[query] 1 - 341 (346)
[subject] 1 - 340 (342)
1e-129 464   65%
Product
D-alanine--D-alanine ligase 4
D-Ala-D-Ala ligase 4
D-alanylalanine synthetase 4
Gene
vanB2
ddl4
Organism
Enterococcus faecalis
Streptococcus faecalis
1uniprot[Pubmed] 19029325
Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2201, encoding erythromycin resistance and cytolysin (Hly/Bac).(Antimicrob. Agents Chemother.) [2009]