BLAST table : Actino_00170

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accessionDBtoolalignmentEvalueScoreIdent.linkproductgeneorganismec
1
D6EWA8_STRLI
(D6EWA8)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
1e-145 518   100% Ketoacyl reductase SSPG_02603 Streptomyces lividans TK24
2
ACT3_STRCO
(P16544)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
1e-145 518   100% Putative ketoacyl reductase actIII
SCO5086
SCBAC28G1.12c
Streptomyces coelicolor 1.3.1.-
3
D3U1V1_9BACT
(D3U1V1)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
1e-102 376   73% Keto reductase uncultured soil bacterium V167
4
Q9FCM4_STRAT
(Q9FCM4)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
1e-101 371   70% Putative keto reductase Streptomyces antibioticus
5
Q54280_SACHI
(Q54280)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
1e-100 369   71% Polyketide reductase Saccharopolyspora hirsuta
6
B5G888_9ACTO
(B5G888)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
2e-99 366   67% Monensin polyketide synthase ketoacyl reductase SSBG_00496 Streptomyces sp. SPB74
7
Q7WT12_9ACTO
(Q7WT12)
Jump to Medem_00300
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
3e-99 365   69% Keto reductase (KR) med-ORF6 Streptomyces sp. AM-7161
8
E3J3Q6_FRASU
(E3J3Q6)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
6e-98 361   69% Short-chain dehydrogenase/reductase SDR FraEuI1c_1326 Frankia sp. (strain EuI1c)
9
DHK1_STRVN
(P16542)
Jump to Grana_00250
[query] 8 - 261 (261)
[subject] 19 - 272 (272)
1e-97 360   75% Granaticin polyketide synthase putative ketoacyl reductase 1
ORF5
gra-orf5 Streptomyces violaceoruber 1.3.1.-
10
E3T4A9_9ACTO
(E3T4A9)
[query] 8 - 261 (261)
[subject] 19 - 272 (272)
1e-96 357   73% Polyketide ketoreductase gra-orf5 Streptomyces vietnamensis
11
D3D3B6_9ACTO
(D3D3B6)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
3e-95 352   68% Short-chain dehydrogenase/reductase SDR FrEUN1fDRAFT_4286 Frankia sp. EUN1f
12
D9UBR2_STRPR
(D9UBR2)
[query] 3 - 261 (261)
[subject] 11 - 269 (269)
5e-95 351   69% Putative ketoreductase cpp22 Streptomyces pristinaespiralis 1.1.1.100
13
B5HIU4_STRPR
(B5HIU4)
[query] 3 - 261 (261)
[subject] 11 - 269 (269)
5e-95 351   69% Polyketide ketoreductase SSDG_05081 Streptomyces pristinaespiralis ATCC 25486
14
Q9L553_9ACTO
(Q9L553)
Jump to Acla_00050
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
6e-94 348   64% AknA aknA Streptomyces galilaeus
15
Q8VWB5_9ACTO
(Q8VWB5)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
7e-94 348   65% AknA aknA Streptomyces galilaeus
16
Q9AMJ0_STRAT
(Q9AMJ0)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
4e-93 345   66% Putative ketoreductase SimA6
Sim5
simA6
sim5
Streptomyces antibioticus
17
C7PWR3_CATAD
(C7PWR3)
[query] 6 - 261 (261)
[subject] 3 - 258 (258)
1e-92 343   70% Short-chain dehydrogenase/reductase SDR Caci_6493 Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
18
Q935Z6_9ACTO
(Q935Z6)
[query] 3 - 261 (261)
[subject] 6 - 264 (264)
2e-92 343   67% RdmJ rdmJ Streptomyces purpurascens
19
Q54190_9ACTO
(Q54190)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
2e-92 342   64% Ketoacyl reductase aknIII Streptomyces galilaeus 1.3.1.-
20
D7RFJ8_AMYOR
(D7RFJ8)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
1e-91 340   65% Putative ketoreductase bexD Amycolatopsis orientalis subsp. vinearia
21
E8RWS2_MICSL
(E8RWS2)
[query] 3 - 261 (261)
[subject] 2 - 259 (259)
7e-91 338   64% Short-chain dehydrogenase/reductase SDR ML5_4411 Micromonospora sp. (strain L5)
22
D9T2A7_MICAI
(D9T2A7)
[query] 3 - 261 (261)
[subject] 2 - 259 (259)
8e-91 337   64% Short-chain dehydrogenase/reductase SDR Micau_4010 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
23
E8W958_STRFA
(E8W958)
[query] 5 - 261 (261)
[subject] 11 - 267 (267)
1e-90 337   65% Short-chain dehydrogenase/reductase SDR Sfla_5324 Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD)
24
D6MSV3_9ACTO
(D6MSV3)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
3e-90 336   62% SsfU ssfU Streptomyces sp. SF2575
25
C7QAF5_CATAD
(C7QAF5)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
4e-90 335   63% Short-chain dehydrogenase/reductase SDR Caci_3549 Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
26
Q2J5J1_FRASC
(Q2J5J1)
[query] 1 - 261 (261)
[subject] 15 - 275 (275)
2e-89 333   65% Short-chain dehydrogenase/reductase SDR Francci3_4103 Frankia sp. (strain CcI3)
27
Q53484_STRMY
(Q53484)
[query] 1 - 261 (261)
[subject] 1 - 260 (260)
3e-89 332   66% Polyketide ketoreductase MPKR Streptomyces mycarofaciens
28
B5HT05_9ACTO
(B5HT05)
[query] 4 - 261 (261)
[subject] 5 - 262 (262)
6e-89 331   64% 3-oxoacyl-[acyl-carrier-protein] reductase SSEG_02722 Streptomyces sviceus ATCC 29083
29
A1C175_9ACTO
(A1C175)
Jump to Aran_00070
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
1e-88 330   62% Ketoreductase Streptomyces echinatus
30
A4X6Z5_SALTO
(A4X6Z5)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
2e-88 330   64% Short-chain dehydrogenase/reductase SDR Strop_2194 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
31
Q54176_STRFR
(Q54176)
Jump to Urd_00150
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
7e-88 328   60% Putative ketoreductase UrdD Streptomyces fradiae
Streptomyces roseoflavus
32
Q6ZZV9_STRAT
(Q6ZZV9)
Jump to Ovied_00140
[query] 4 - 261 (261)
[subject] 3 - 260 (260)
2e-87 327   62% Ketoreductase ovmT Streptomyces antibioticus
33
Q54491_STRNO
(Q54491)
Jump to Nogl_00330
[query] 1 - 261 (261)
[subject] 1 - 262 (262)
4e-87 325   61% SnoaD snoaD Streptomyces nogalater
34
Q54812_STRPE
(Q54812)
Jump to Adria_00250
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
7e-87 324   58% Daunorubicin-doxorubicin polyketide synthase dpsE Streptomyces peucetius
35
D7BZR7_STRBB
(D7BZR7)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
1e-86 323   63% Short-chain dehydrogenase/reductase SDR SBI_06852 Streptomyces bingchenggensis (strain BCW-1)
36
B6SEF4_9ACTO
(B6SEF4)
Jump to Alnu_00090
[query] 9 - 261 (261)
[subject] 11 - 263 (263)
1e-86 323   65% AlnP ketoreductase alnP Streptomyces sp. CM020
37
F2RC18_STRVP
(F2RC18)
[query] 4 - 261 (261)
[subject] 7 - 264 (264)
3e-86 322   61% Acetoacetyl-CoA reductase SVEN_5983 Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745) 1.1.1.36
38
Q84CH9_9ACTO
(Q84CH9)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
3e-85 319   61% Putative ketoreductase pd2E Streptomyces sp. WP 4669
39
Q93LY1_9ACTO
(Q93LY1)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
5e-85 318   59% Polyketide ketoreductase PgaD pgaD Streptomyces sp. PGA64
40
Q67G28_9ACTO
(Q67G28)
Jump to Heda_00300
[query] 7 - 261 (261)
[subject] 5 - 259 (259)
6e-85 318   62% Keto reductase Streptomyces griseoruber
41
C4NYK2_9ACTO
(C4NYK2)
[query] 8 - 261 (261)
[subject] 1 - 254 (254)
6e-85 318   61% SaqD saqD Micromonospora sp. Tu 6368
42
Q47QL0_THEFY
(Q47QL0)
[query] 3 - 261 (261)
[subject] 2 - 261 (261)
6e-85 318   61% Ketoacyl reductase Tfu_1221 Thermobifida fusca (strain YX)
43
Q4R0M6_STRCX
(Q4R0M6)
Jump to Chart_00060
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
1e-84 317   62% ChaD protein chaD Streptomyces chartreusis
44
Q83X41_STRRO
(Q83X41)
[query] 8 - 261 (261)
[subject] 7 - 260 (260)
1e-84 317   61% Ketoreductase rocG Streptomyces rochei
Streptomyces parvullus
45
D5MRI8_9ACTO
(D5MRI8)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
3e-84 315   62% Putative ketoreductase hrbO Streptomyces sp. 2238-SVT4
46
D9W5A8_9ACTO
(D9W5A8)
[query] 4 - 261 (261)
[subject] 12 - 269 (269)
8e-84 314   60% 3-oxoacyl-[acyl-carrier-protein] reductase SSNG_07338 Streptomyces sp. C
47
Q2HR23_9ACTO
(Q2HR23)
Jump to Sch475_00350
[query] 5 - 261 (261)
[subject] 10 - 266 (266)
8e-84 314   60% Putative ketoreducatse schP5 Streptomyces sp. SCC 2136
48
Q56166_9ACTO
(Q56166)
Jump to Jado_00110
[query] 4 - 261 (261)
[subject] 7 - 264 (264)
9e-84 314   59% Ketoreductase Streptomyces venezuelae
49
Q56H99_STRAU
(Q56H99)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
1e-83 313   59% Aur1G aur1G Streptomyces aureofaciens
50
Q54220_STRGR
(Q54220)
Jump to Griseu_00040
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
2e-83 313   59% Ketoreductase Streptomyces griseus
accessionDBtoolalignmentEvalueScoreIdent.linkinformationpubmed
2
ACT3_STRCO
(P16544)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
1e-145 518   100%
Product
Putative ketoacyl reductase
Gene
actIII
SCO5086
SCBAC28G1.12c
Organism
Streptomyces coelicolor
1uniprot[Pubmed] 2469622 [Medline] 89232723
Nucleotide sequence, transcription and deduced function of a gene involved in polyketide antibiotic synthesis in Streptomyces coelicolor.(Gene) [1988]
2uniprot[Pubmed] 12000953 [Medline] 21996410
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002]
3uniprot[Pubmed] 15544323
Structural analysis of actinorhodin polyketide ketoreductase: cofactor binding and substrate specificity.(Biochemistry) [2004]
4uniprot[Pubmed] 15458634
The crystal structure of the actIII actinorhodin polyketide reductase: proposed mechanism for ACP and polyketide binding.(Structure) [2004]
[pubmed all]
4
Q9FCM4_STRAT
(Q9FCM4)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
1e-101 371   70%
Product
Putative keto reductase
Gene
 
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 11700358 [Medline] 21557167
A polyketide biosynthetic gene cluster from Streptomyces antibioticus includes a LysR-type transcriptional regulator.(Microbiology) [2001]
5
Q54280_SACHI
(Q54280)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
1e-100 369   71%
Product
Polyketide reductase
Gene
 
Organism
Saccharopolyspora hirsuta
1uniprot[Pubmed] 8341260 [Medline] 93341453
Saccharopolyspora hirsuta 367 encodes clustered genes similar to ketoacyl synthase, ketoacyl reductase, acyl carrier protein, and biotin carboxyl carrier protein.(Mol. Gen. Genet.) [1993]
7
Q7WT12_9ACTO
(Q7WT12)
Jump to Medem_00300
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
3e-99 365   69%
Product
Keto reductase (KR)
Gene
med-ORF6
Organism
Streptomyces sp. AM-7161
1uniprot
Cloning, sequencing and heterologous expression of the medermycin biosynthetic gene cluster of Streptomyces sp. AM-7161: towards comparative analysis of the benzoisochromanequione gene clusters.(Microbiology (Mosc.)) [2003]
9
DHK1_STRVN
(P16542)
Jump to Grana_00250
[query] 8 - 261 (261)
[subject] 19 - 272 (272)
1e-97 360   75%
Product
Granaticin polyketide synthase putative ketoacyl reductase 1
ORF5
Gene
gra-orf5
Organism
Streptomyces violaceoruber
1uniprot[Pubmed] 2583128 [Medline] 90060034
Structure and deduced function of the granaticin-producing polyketide synthase gene cluster of Streptomyces violaceoruber Tu22.(EMBO J.) [1989]
2uniprot[Pubmed] 7476861 [Medline] 96027933
Identification of Streptomyces violaceoruber Tu22 genes involved in the biosynthesis of granaticin.(Mol. Gen. Genet.) [1995]
3uniprot[Pubmed] 9831526 [Medline] 99051446
The granaticin biosynthetic gene cluster of Streptomyces violaceoruber Tu22: sequence analysis and expression in a heterologous host.(Chem. Biol.) [1998]
[pubmed all]
12
D9UBR2_STRPR
(D9UBR2)
[query] 3 - 261 (261)
[subject] 11 - 269 (269)
5e-95 351   69%
Product
Putative ketoreductase
Gene
cpp22
Organism
Streptomyces pristinaespiralis
1uniprot[Pubmed] 21342465
Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis.(Microb Biotechnol) [2011]
14
Q9L553_9ACTO
(Q9L553)
Jump to Acla_00050
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
6e-94 348   64%
Product
AknA
Gene
aknA
Organism
Streptomyces galilaeus
1uniprot[Pubmed] 12137949 [Medline] 22133312
Cloning and characterization of Streptomyces galilaeus aclacinomycins polyketide synthase (PKS) cluster.(Gene) [2002]
15
Q8VWB5_9ACTO
(Q8VWB5)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
7e-94 348   65%
Product
AknA
Gene
aknA
Organism
Streptomyces galilaeus
1uniprot[Pubmed] 12399480 [Medline] 22286521
Expression, purification, and characterization of AknX anthrone oxygenase, which is involved in aklavinone biosynthesis in Streptomyces galilaeus.(J. Bacteriol.) [2002]
16
Q9AMJ0_STRAT
(Q9AMJ0)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
4e-93 345   66%
Product
Putative ketoreductase SimA6
Sim5
Gene
simA6
sim5
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 11959542 [Medline] 21955989
Biosynthetic gene cluster of simocyclinone, a natural multihybrid antibiotic.(Antimicrob. Agents Chemother.) [2002]
2uniprot[Pubmed] 12115055 [Medline] 22109063
Cloning and analysis of the simocyclinone biosynthetic gene cluster of Streptomyces antibioticus Tu 6040.(Arch. Microbiol.) [2002]
[pubmed all]
17
C7PWR3_CATAD
(C7PWR3)
[query] 6 - 261 (261)
[subject] 3 - 258 (258)
1e-92 343   70%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Caci_6493
Organism
Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
1uniprot
Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).(Stand. Genomic Sci.) [2009]
19
Q54190_9ACTO
(Q54190)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
2e-92 342   64%
Product
Ketoacyl reductase
Gene
aknIII
Organism
Streptomyces galilaeus
1uniprot[Pubmed] 8157619 [Medline] 94209255
Nucleotide sequence of the aknA region of the aklavinone biosynthetic gene cluster of Streptomyces galilaeus.(J. Bacteriol.) [1994]
20
D7RFJ8_AMYOR
(D7RFJ8)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
1e-91 340   65%
Product
Putative ketoreductase
Gene
bexD
Organism
Amycolatopsis orientalis subsp. vinearia
1uniprot[Pubmed] 20443562
A biosynthetic pathway for BE-7585A, a 2-thiosugar-containing angucycline-type natural product.(J. Am. Chem. Soc.) [2010]
24
D6MSV3_9ACTO
(D6MSV3)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
3e-90 336   62%
Product
SsfU
Gene
ssfU
Organism
Streptomyces sp. SF2575
1uniprot[Pubmed] 19908837
Biochemical analysis of the biosynthetic pathway of an anticancer tetracycline SF2575.(J. Am. Chem. Soc.) [2009]
25
C7QAF5_CATAD
(C7QAF5)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
4e-90 335   63%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Caci_3549
Organism
Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
1uniprot
Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).(Stand. Genomic Sci.) [2009]
26
Q2J5J1_FRASC
(Q2J5J1)
[query] 1 - 261 (261)
[subject] 15 - 275 (275)
2e-89 333   65%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Francci3_4103
Organism
Frankia sp. (strain CcI3)
1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]
27
Q53484_STRMY
(Q53484)
[query] 1 - 261 (261)
[subject] 1 - 260 (260)
3e-89 332   66%
Product
Polyketide ketoreductase
Gene
MPKR
Organism
Streptomyces mycarofaciens
1uniprot[Pubmed] 7893937 [Medline] 95201158
Characterization of polyketide ketoreductase gene (MPKR) from midecamycin-producing strain (Streptomyces mycarofaciens 1748).(Chin. J. Biotechnol.) [1994]
31
Q54176_STRFR
(Q54176)
Jump to Urd_00150
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
7e-88 328   60%
Product
Putative ketoreductase
Gene
UrdD
Organism
Streptomyces fradiae
Streptomyces roseoflavus
1uniprot[Pubmed] 7592377 [Medline] 96042088
Cloning and characterization of a polyketide synthase from Streptomyces fradiae Tue2717 encoding the genes for biosynthesis of the angucycline antibiotic urdamycin A and a gene probably involved in its oxygenation.(J. Bacteriol.) [1995]
33
Q54491_STRNO
(Q54491)
Jump to Nogl_00330
[query] 1 - 261 (261)
[subject] 1 - 262 (262)
4e-87 325   61%
Product
SnoaD
Gene
snoaD
Organism
Streptomyces nogalater
1uniprot[Pubmed] 8668120 [Medline] 96242142
A gene cluster involved in nogalamycin biosynthesis from Streptomyces nogalater: sequence analysis and complementation of early-block mutations in the anthracycline pathway.(Mol. Gen. Genet.) [1996]
2uniprot[Pubmed] 9349712 [Medline] 98007868
Characterization of Streptomyces nogalater genes encoding enzymes involved in glycosylation steps in nogalamycin biosynthesis.(Mol. Gen. Genet.) [1997]
3uniprot[Pubmed] 8760909 [Medline] 96349102
Production of hybrid anthracycline antibiotics by heterologous expression of Streptomyces nogalater nogalamycin biosynthesis genes.(Microbiology) [1996]
[pubmed all]
34
Q54812_STRPE
(Q54812)
Jump to Adria_00250
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
7e-87 324   58%
Product
Daunorubicin-doxorubicin polyketide synthase
Gene
dpsE
Organism
Streptomyces peucetius
1uniprot[Pubmed] 7828855 [Medline] 95129838
Characterization of the Streptomyces peucetius ATCC 29050 genes encoding doxorubicin polyketide synthase.(Gene) [1994]
35
D7BZR7_STRBB
(D7BZR7)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
1e-86 323   63%
Product
Short-chain dehydrogenase/reductase SDR
Gene
SBI_06852
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
36
B6SEF4_9ACTO
(B6SEF4)
Jump to Alnu_00090
[query] 9 - 261 (261)
[subject] 11 - 263 (263)
1e-86 323   65%
Product
AlnP ketoreductase
Gene
alnP
Organism
Streptomyces sp. CM020
1uniprot[Pubmed] 18940666
Characterization of the alnumycin gene cluster reveals unusual gene products for pyran ring formation and dioxan biosynthesis.(Chem. Biol.) [2008]
37
F2RC18_STRVP
(F2RC18)
[query] 4 - 261 (261)
[subject] 7 - 264 (264)
3e-86 322   61%
Product
Acetoacetyl-CoA reductase
Gene
SVEN_5983
Organism
Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
1uniprot[Pubmed] 21463507
Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011]
39
Q93LY1_9ACTO
(Q93LY1)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
5e-85 318   59%
Product
Polyketide ketoreductase PgaD
Gene
pgaD
Organism
Streptomyces sp. PGA64
1uniprot[Pubmed] 12654660 [Medline] 22540650
Engineering anthracycline biosynthesis toward angucyclines.(Antimicrob. Agents Chemother.) [2003]
2uniprot[Pubmed] 15515887
Partial activation of a silent angucycline-type gene cluster from a rubromycin beta producing Streptomyces sp. PGA64.(J. Antibiot.) [2004]
[pubmed all]
40
Q67G28_9ACTO
(Q67G28)
Jump to Heda_00300
[query] 7 - 261 (261)
[subject] 5 - 259 (259)
6e-85 318   62%
Product
Keto reductase
Gene
 
Organism
Streptomyces griseoruber
1uniprot[Pubmed] 15271354
The hedamycin locus implicates a novel aromatic PKS priming mechanism.(Chem. Biol.) [2004]
41
C4NYK2_9ACTO
(C4NYK2)
[query] 8 - 261 (261)
[subject] 1 - 254 (254)
6e-85 318   61%
Product
SaqD
Gene
saqD
Organism
Micromonospora sp. Tu 6368
1uniprot[Pubmed] 17497146
A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007]
2uniprot[Pubmed] 19384899
Cloning and sequencing of the biosynthetic gene cluster for saquayamycin z and galtamycin B and the elucidation of the assembly of their saccharide chains.(Chembiochem) [2009]
[pubmed all]
42
Q47QL0_THEFY
(Q47QL0)
[query] 3 - 261 (261)
[subject] 2 - 261 (261)
6e-85 318   61%
Product
Ketoacyl reductase
Gene
Tfu_1221
Organism
Thermobifida fusca (strain YX)
1uniprot[Pubmed] 17209016
Genome sequence and analysis of the soil cellulolytic actinomycete Thermobifida fusca YX.(J. Bacteriol.) [2007]
43
Q4R0M6_STRCX
(Q4R0M6)
Jump to Chart_00060
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
1e-84 317   62%
Product
ChaD protein
Gene
chaD
Organism
Streptomyces chartreusis
1uniprot[Pubmed] 15911378
Biosynthesis of the antitumor agent chartreusin involves the oxidative rearrangement of an anthracyclic polyketide.(Chem. Biol.) [2005]
44
Q83X41_STRRO
(Q83X41)
[query] 8 - 261 (261)
[subject] 7 - 260 (260)
1e-84 317   61%
Product
Ketoreductase
Gene
rocG
Organism
Streptomyces rochei
Streptomyces parvullus
1uniprot[Pubmed] 12791134 [Medline] 22676866
The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism.(Mol. Microbiol.) [2003]
2uniprot[Pubmed] 10954087 [Medline] 20408175
Cloning and analysis of the replication origin and the telomeres of the large linear plasmid pSLA2-L in Streptomyces rochei.(Mol. Gen. Genet.) [2000]
3uniprot[Pubmed] 10767533 [Medline] 20231737
Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei.(Gene) [2000]
4uniprot[Pubmed] 9836424 [Medline] 99053144
Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs.(Biosci. Biotechnol. Biochem.) [1998]
[pubmed all]
45
D5MRI8_9ACTO
(D5MRI8)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
3e-84 315   62%
Product
Putative ketoreductase
Gene
hrbO
Organism
Streptomyces sp. 2238-SVT4
1uniprot[Pubmed] 20453135
Cloning and characterization of a gene cluster for hatomarubigin biosynthesis in Streptomyces sp. strain 2238-SVT4.(Appl. Environ. Microbiol.) [2010]
47
Q2HR23_9ACTO
(Q2HR23)
Jump to Sch475_00350
[query] 5 - 261 (261)
[subject] 10 - 266 (266)
8e-84 314   60%
Product
Putative ketoreducatse
Gene
schP5
Organism
Streptomyces sp. SCC 2136
1uniprot
Angucyclines Sch 47554 and Sch 47555 from Streptomyces sp. SCC-2136: Cloning, Sequencing, and Characterization.(Mol. Cells) [2006]
2uniprot
Molecular cloning and characterization of biosynthetic genes cluster of Sch 47554 from Streptomyces sp. SCC 2136. [2004]
48
Q56166_9ACTO
(Q56166)
Jump to Jado_00110
[query] 4 - 261 (261)
[subject] 7 - 264 (264)
9e-84 314   59%
Product
Ketoreductase
Gene
 
Organism
Streptomyces venezuelae
1uniprot[Pubmed] 7881555 [Medline] 95187308
Cloning and characterization of polyketide synthase genes for jadomycin B biosynthesis in Streptomyces venezuelae ISP5230.(Microbiology) [1994]
2uniprot
Functional characterization of the jadI gene as a cyclase forming angucyclinones.(J. Am. Chem. Soc.) [1999]
49
Q56H99_STRAU
(Q56H99)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
1e-83 313   59%
Product
Aur1G
Gene
aur1G
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 12384301 [Medline] 22271582
Cloning and characterization of a polyketide synthase gene cluster involved in biosynthesis of a proposed angucycline-like polyketide auricin in Streptomyces aureofaciens CCM 3239.(Gene) [2002]
2uniprot[Pubmed] 16079347
Characterization of a regulatory gene essential for the production of the angucycline-like polyketide antibiotic auricin in Streptomyces aureofaciens CCM 3239.(Microbiology) [2005]
3uniprot[Pubmed] 20466770
The role of the TetR-family transcriptional regulator Aur1R in negative regulation of the auricin gene cluster in Streptomyces aureofaciens CCM 3239.(Microbiology) [2010]
[pubmed all]
50
Q54220_STRGR
(Q54220)
Jump to Griseu_00040
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
2e-83 313   59%
Product
Ketoreductase
Gene
 
Organism
Streptomyces griseus
1uniprot[Pubmed] 8169211 [Medline] 94222841
Cloning, sequencing, and analysis of the griseusin polyketide synthase gene cluster from Streptomyces griseus.(J. Bacteriol.) [1994]