BLAST table : Amph_00060

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accessionDBtoolalignmentEvalueScoreIdent.linkproductgeneorganismec
1
Q93NX7_9ACTO
(Q93NX7)
[query] 1 - 2034 (2034)
[subject] 1 - 2034 (2034)
0.0 3979   100% AmphK amphK Streptomyces nodosus
2
Q9L4X1_9ACTO
(Q9L4X1)
Jump to Nysta_00070
[query] 1 - 2030 (2034)
[subject] 1 - 2062 (2066)
0.0 2848   75% NysK nysK Streptomyces noursei
3
D2CKL7_PSEAH
(D2CKL7)
[query] 1 - 2030 (2034)
[subject] 1 - 2023 (2031)
0.0 2598   72% CppK cppK Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
4
D9WB10_9ACTO
(D9WB10)
[query] 31 - 2032 (2034)
[subject] 22 - 2007 (2010)
0.0 2098   59% Modular polyketide synthase SSOG_00516 Streptomyces himastatinicus ATCC 53653
5
F1CLA7_9ACTO
(F1CLA7)
[query] 1 - 2029 (2034)
[subject] 1 - 2018 (2021)
0.0 1920   55% ScnS4 scnS4 Streptomyces chattanoogensis
6
Q6W5P8_9ACTO
(Q6W5P8)
Jump to FR008_00180
[query] 1 - 2025 (2034)
[subject] 1 - 2030 (2049)
0.0 1887   55% FscF fscF Streptomyces sp. FR-008
7
Q9EWA3_9ACTO
(Q9EWA3)
Jump to Pimar_00050
[query] 2 - 2029 (2034)
[subject] 6 - 2021 (2024)
0.0 1851   54% PimS4 protein pimS4 Streptomyces natalensis
8
E0KQM4_STRVO
(E0KQM4)
[query] 4 - 2030 (2034)
[subject] 3 - 2083 (2087)
0.0 1677   51% 6-deoxyerythronolide-B synthase StrviDRAFT_4951 Streptomyces violaceusniger Tu 4113 2.3.1.94
9
Q76KZ3_STRHA
(Q76KZ3)
Jump to Vicen_00070
[query] 34 - 2028 (2034)
[subject] 1759 - 3806 (3808)
(3 hsp)
0.0 1664   50% Polyketide synthase modules 7-8 vinP4 Streptomyces halstedii
10
D7C2B8_STRBB
(D7C2B8)
[query] 34 - 1738 (2034)
[subject] 3639 - 5360 (7498)
(7 hsp)
0.0 1658   56% Type I modular polyketide synthase pks3-2
SBI_00651
Streptomyces bingchenggensis (strain BCW-1)
11
Q93NW6_9ACTO
(Q93NW6)
Jump to Amph_00170
[query] 5 - 1738 (2034)
[subject] 6 - 1740 (10917)
(7 hsp)
0.0 1649   55% AmphC amphC Streptomyces nodosus
12
Q93NX8_9ACTO
(Q93NX8)
Jump to Amph_00050
[query] 6 - 1738 (2034)
[subject] 11 - 1777 (5644)
(4 hsp)
0.0 1643   54% AmphJ amphJ Streptomyces nodosus
13
F1CLA8_9ACTO
(F1CLA8)
[query] 17 - 1747 (2034)
[subject] 21 - 1735 (1813)
0.0 1637   56% ScnS3 scnS3 Streptomyces chattanoogensis
14
D9WB05_9ACTO
(D9WB05)
[query] 1 - 1751 (2034)
[subject] 1 - 1758 (2718)
(2 hsp)
0.0 1626   54% Modular polyketide synthase SSOG_00511 Streptomyces himastatinicus ATCC 53653
15
Q9EWA2_9ACTO
(Q9EWA2)
Jump to Pimar_00060
[query] 7 - 1747 (2034)
[subject] 8 - 1734 (1808)
0.0 1623   55% PimS3 protein pimS3 Streptomyces natalensis
16
Q52V49_9ACTO
(Q52V49)
[query] 34 - 2026 (2034)
[subject] 1798 - 3868 (3872)
(2 hsp)
0.0 1623   49% Polyketide synthase type I Streptomyces aizunensis
17
E0L075_STRVO
(E0L075)
[query] 1 - 1740 (2034)
[subject] 1 - 1782 (5786)
(5 hsp)
0.0 1623   53% Beta-ketoacyl synthase StrviDRAFT_8303 Streptomyces violaceusniger Tu 4113
18
E0L044_STRVO
(E0L044)
[query] 34 - 1735 (2034)
[subject] 3613 - 5343 (7224)
(5 hsp)
0.0 1622   54% Beta-ketoacyl synthase StrviDRAFT_8272 Streptomyces violaceusniger Tu 4113
19
Q9L4W3_9ACTO
(Q9L4W3)
Jump to Nysta_00150
[query] 6 - 1738 (2034)
[subject] 7 - 1735 (11096)
(7 hsp)
0.0 1618   56% NysC nysC Streptomyces noursei
20
Q9EWA1_9ACTO
(Q9EWA1)
Jump to Pimar_00070
[query] 1 - 1738 (2034)
[subject] 1 - 1770 (9507)
(11 hsp)
0.0 1605   54% PimS2 protein pimS2 Streptomyces natalensis
21
D2CKM4_PSEAH
(D2CKM4)
[query] 4 - 1738 (2034)
[subject] 5 - 1744 (10876)
(7 hsp)
0.0 1605   55% CppC cppC Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
22
F1CLA9_9ACTO
(F1CLA9)
[query] 1 - 1772 (2034)
[subject] 1 - 1799 (9498)
(11 hsp)
0.0 1598   54% ScnS2 scnS2 Streptomyces chattanoogensis
23
Q9ALM2_9PSEU
(Q9ALM2)
Jump to Spino_00210
[query] 36 - 2029 (2034)
[subject] 3559 - 5580 (5588)
(3 hsp)
0.0 1594   49% Polyketide synthase extender modules 8-10 spnE Saccharopolyspora spinosa
24
Q93HJ1_STRAW
(Q93HJ1)
Jump to Oligo_00120
[query] 34 - 2026 (2034)
[subject] 1565 - 3608 (3613)
(3 hsp)
0.0 1588   48% Modular polyketide synthase olmA7
SAV2895
SAV_2895
Streptomyces avermitilis
25
D9WQ64_9ACTO
(D9WQ64)
[query] 34 - 1764 (2034)
[subject] 1004 - 2770 (3874)
(4 hsp)
0.0 1577   52% Modular polyketide synthase SSOG_05738 Streptomyces himastatinicus ATCC 53653
26
E0L074_STRVO
(E0L074)
[query] 3 - 1737 (2034)
[subject] 2 - 1809 (2461)
(2 hsp)
0.0 1576   51% Mycocerosate synthase., 6-deoxyerythronolide-B synthase StrviDRAFT_8302 Streptomyces violaceusniger Tu 4113 2.3.1.111

2.3.1.94
27
E0KBI1_STRVO
(E0KBI1)
[query] 34 - 1738 (2034)
[subject] 1597 - 3370 (3456)
(3 hsp)
0.0 1576   52% Acyl transferase StrviDRAFT_0196 Streptomyces violaceusniger Tu 4113
28
D9WQ83_9ACTO
(D9WQ83)
[query] 1 - 1745 (2034)
[subject] 10 - 1793 (3002)
(2 hsp)
0.0 1575   52% Modular polyketide synthase SSOG_05757 Streptomyces himastatinicus ATCC 53653
29
Q6W5P6_9ACTO
(Q6W5P6)
Jump to FR008_00200
[query] 1 - 1740 (2034)
[subject] 6 - 1767 (9550)
(11 hsp)
0.0 1571   55% FscD fscD Streptomyces sp. FR-008
30
D9WB22_9ACTO
(D9WB22)
[query] 1 - 1738 (2034)
[subject] 1 - 1749 (2425)
(2 hsp)
0.0 1570   52% Modular polyketide synthase SSOG_00528 Streptomyces himastatinicus ATCC 53653
31
E0KFI7_STRVO
(E0KFI7)
[query] 34 - 1738 (2034)
[subject] 3306 - 5094 (8538)
(7 hsp)
0.0 1568   52% Beta-ketoacyl synthase StrviDRAFT_1370 Streptomyces violaceusniger Tu 4113
32
F1CLC1_9ACTO
(F1CLC1)
[query] 34 - 1738 (2034)
[subject] 3331 - 5012 (6831)
(5 hsp)
0.0 1563   54% ScnS1 scnS1 Streptomyces chattanoogensis
33
D9WQ85_9ACTO
(D9WQ85)
[query] 36 - 2027 (2034)
[subject] 1864 - 3913 (3914)
(3 hsp)
0.0 1563   48% Modular polyketide synthase SSOG_05759 Streptomyces himastatinicus ATCC 53653
34
A8J706_9ACTO
(A8J706)
[query] 34 - 2029 (2034)
[subject] 3096 - 5160 (5166)
(5 hsp)
0.0 1563   49% Modular polyketide synthase nemA4 Streptomyces cyaneogriseus subsp. noncyanogenus
35
C3VLW8_9ACTO
(C3VLW8)
[query] 4 - 2029 (2034)
[subject] 5 - 1985 (1986)
0.0 1560   48% Polyketide synthase type I becG Streptomyces sp. DSM 21069
36
C6WNV0_ACTMD
(C6WNV0)
[query] 34 - 2029 (2034)
[subject] 3414 - 5400 (5400)
(3 hsp)
0.0 1558   49% Short-chain dehydrogenase/reductase SDR Amir_2684 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
37
Q9L4X2_9ACTO
(Q9L4X2)
Jump to Nysta_00060
[query] 36 - 1746 (2034)
[subject] 3636 - 5358 (5435)
(5 hsp)
0.0 1558   56% NysJ nysJ Streptomyces noursei
38
D7BRD4_STRBB
(D7BRD4)
[query] 34 - 1758 (2034)
[subject] 2816 - 4590 (9950)
(7 hsp)
0.0 1556   53% Short-chain dehydrogenase/reductase SDR SBI_01976 Streptomyces bingchenggensis (strain BCW-1)
39
E0KFI9_STRVO
(E0KFI9)
[query] 34 - 1738 (2034)
[subject] 3232 - 5010 (8238)
(10 hsp)
0.0 1555   53% Beta-ketoacyl synthase StrviDRAFT_1372 Streptomyces violaceusniger Tu 4113
40
Q9X993_9ACTO
(Q9X993)
Jump to Pimar_00170
[query] 34 - 1738 (2034)
[subject] 3299 - 4978 (6797)
(5 hsp)
0.0 1549   54% PimS1 protein
Polyketide synthase
pimS1 Streptomyces natalensis
41
D7C2C3_STRBB
(D7C2C3)
[query] 1 - 1738 (2034)
[subject] 1 - 1849 (4868)
(5 hsp)
0.0 1548   51% Modular polyketide synthase pks3-4
SBI_00656
Streptomyces bingchenggensis (strain BCW-1)
42
D9WQL0_9ACTO
(D9WQL0)
[query] 4 - 2029 (2034)
[subject] 55 - 2033 (2034)
0.0 1547   48% Modular polyketide synthase SSOG_07857 Streptomyces himastatinicus ATCC 53653
43
C3VLZ6_9ACTO
(C3VLZ6)
[query] 4 - 2029 (2034)
[subject] 5 - 1991 (1992)
0.0 1546   47% Polyketide synthase type I mlaG Streptomyces sp. MP39-85
44
B4VB11_9ACTO
(B4VB11)
[query] 34 - 1746 (2034)
[subject] 2085 - 3849 (3928)
(3 hsp)
0.0 1545   54% Polyketide synthase type I SSAG_04921 Streptomyces sp. Mg1
45
D2CKL6_PSEAH
(D2CKL6)
[query] 42 - 1746 (2034)
[subject] 3648 - 5348 (5425)
(5 hsp)
0.0 1545   56% CppJ cppJ Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
46
Q52V50_9ACTO
(Q52V50)
[query] 1 - 1763 (2034)
[subject] 6 - 1836 (7510)
(5 hsp)
0.0 1543   52% Polyketide synthase type I Streptomyces aizunensis
47
Q6JHN6_9PSEU
(Q6JHN6)
[query] 1 - 1764 (2034)
[subject] 30 - 1770 (7488)
(5 hsp)
0.0 1542   52% ObsC Saccharopolyspora spinosa
48
Q52V46_9ACTO
(Q52V46)
[query] 2 - 1738 (2034)
[subject] 3181 - 4975 (8147)
(10 hsp)
0.0 1539   52% Polyketide synthase type I Streptomyces aizunensis
49
B4VDY6_9ACTO
(B4VDY6)
[query] 28 - 1738 (2034)
[subject] 13 - 1749 (4894)
(3 hsp)
0.0 1538   53% Polyketide synthase type I SSAG_05828 Streptomyces sp. Mg1
50
Q93NX9_9ACTO
(Q93NX9)
Jump to Amph_00040
[query] 1 - 1738 (2034)
[subject] 1 - 1752 (9510)
(11 hsp)
0.0 1534   53% AmphI amphI Streptomyces nodosus
accessionDBtoolalignmentEvalueScoreIdent.linkinformationpubmed
1
Q93NX7_9ACTO
(Q93NX7)
[query] 1 - 2034 (2034)
[subject] 1 - 2034 (2034)
0.0 3979   100%
Product
AmphK
Gene
amphK
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
[pubmed all]
2
Q9L4X1_9ACTO
(Q9L4X1)
Jump to Nysta_00070
[query] 1 - 2030 (2034)
[subject] 1 - 2062 (2066)
0.0 2848   75%
Product
NysK
Gene
nysK
Organism
Streptomyces noursei
1uniprot[Pubmed] 10873841 [Medline] 20334850
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000]
3
D2CKL7_PSEAH
(D2CKL7)
[query] 1 - 2030 (2034)
[subject] 1 - 2023 (2031)
0.0 2598   72%
Product
CppK
Gene
cppK
Organism
Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
1uniprot[Pubmed] 19697072
Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009]
5
F1CLA7_9ACTO
(F1CLA7)
[query] 1 - 2029 (2034)
[subject] 1 - 2018 (2021)
0.0 1920   55%
Product
ScnS4
Gene
scnS4
Organism
Streptomyces chattanoogensis
1uniprot[Pubmed] 21330439
The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011]
6
Q6W5P8_9ACTO
(Q6W5P8)
Jump to FR008_00180
[query] 1 - 2025 (2034)
[subject] 1 - 2030 (2049)
0.0 1887   55%
Product
FscF
Gene
fscF
Organism
Streptomyces sp. FR-008
1uniprot[Pubmed] 14652074
Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003]
7
Q9EWA3_9ACTO
(Q9EWA3)
Jump to Pimar_00050
[query] 2 - 2029 (2034)
[subject] 6 - 2021 (2024)
0.0 1851   54%
Product
PimS4 protein
Gene
pimS4
Organism
Streptomyces natalensis
1uniprot[Pubmed] 11094342 [Medline] 20547809
A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000]
9
Q76KZ3_STRHA
(Q76KZ3)
Jump to Vicen_00070
[query] 34 - 2028 (2034)
[subject] 1759 - 3806 (3808)
(3 hsp)
0.0 1664   50%
Product
Polyketide synthase modules 7-8
Gene
vinP4
Organism
Streptomyces halstedii
1uniprot[Pubmed] 15112997
Cloning, sequencing, and functional analysis of the biosynthetic gene cluster of macrolactam antibiotic vicenistatin in Streptomyces halstedii.(Chem. Biol.) [2004]
10
D7C2B8_STRBB
(D7C2B8)
[query] 34 - 1738 (2034)
[subject] 3639 - 5360 (7498)
(7 hsp)
0.0 1658   56%
Product
Type I modular polyketide synthase
Gene
pks3-2
SBI_00651
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
11
Q93NW6_9ACTO
(Q93NW6)
Jump to Amph_00170
[query] 5 - 1738 (2034)
[subject] 6 - 1740 (10917)
(7 hsp)
0.0 1649   55%
Product
AmphC
Gene
amphC
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
[pubmed all]
12
Q93NX8_9ACTO
(Q93NX8)
Jump to Amph_00050
[query] 6 - 1738 (2034)
[subject] 11 - 1777 (5644)
(4 hsp)
0.0 1643   54%
Product
AmphJ
Gene
amphJ
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
[pubmed all]
13
F1CLA8_9ACTO
(F1CLA8)
[query] 17 - 1747 (2034)
[subject] 21 - 1735 (1813)
0.0 1637   56%
Product
ScnS3
Gene
scnS3
Organism
Streptomyces chattanoogensis
1uniprot[Pubmed] 21330439
The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011]
15
Q9EWA2_9ACTO
(Q9EWA2)
Jump to Pimar_00060
[query] 7 - 1747 (2034)
[subject] 8 - 1734 (1808)
0.0 1623   55%
Product
PimS3 protein
Gene
pimS3
Organism
Streptomyces natalensis
1uniprot[Pubmed] 11094342 [Medline] 20547809
A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000]
16
Q52V49_9ACTO
(Q52V49)
[query] 34 - 2026 (2034)
[subject] 1798 - 3868 (3872)
(2 hsp)
0.0 1623   49%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
19
Q9L4W3_9ACTO
(Q9L4W3)
Jump to Nysta_00150
[query] 6 - 1738 (2034)
[subject] 7 - 1735 (11096)
(7 hsp)
0.0 1618   56%
Product
NysC
Gene
nysC
Organism
Streptomyces noursei
1uniprot[Pubmed] 10873841 [Medline] 20334850
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000]
20
Q9EWA1_9ACTO
(Q9EWA1)
Jump to Pimar_00070
[query] 1 - 1738 (2034)
[subject] 1 - 1770 (9507)
(11 hsp)
0.0 1605   54%
Product
PimS2 protein
Gene
pimS2
Organism
Streptomyces natalensis
1uniprot[Pubmed] 11094342 [Medline] 20547809
A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000]
21
D2CKM4_PSEAH
(D2CKM4)
[query] 4 - 1738 (2034)
[subject] 5 - 1744 (10876)
(7 hsp)
0.0 1605   55%
Product
CppC
Gene
cppC
Organism
Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
1uniprot[Pubmed] 19697072
Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009]
22
F1CLA9_9ACTO
(F1CLA9)
[query] 1 - 1772 (2034)
[subject] 1 - 1799 (9498)
(11 hsp)
0.0 1598   54%
Product
ScnS2
Gene
scnS2
Organism
Streptomyces chattanoogensis
1uniprot[Pubmed] 21330439
The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011]
23
Q9ALM2_9PSEU
(Q9ALM2)
Jump to Spino_00210
[query] 36 - 2029 (2034)
[subject] 3559 - 5580 (5588)
(3 hsp)
0.0 1594   49%
Product
Polyketide synthase extender modules 8-10
Gene
spnE
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 11358695 [Medline] 21257765
Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001]
24
Q93HJ1_STRAW
(Q93HJ1)
Jump to Oligo_00120
[query] 34 - 2026 (2034)
[subject] 1565 - 3608 (3613)
(3 hsp)
0.0 1588   48%
Product
Modular polyketide synthase
Gene
olmA7
SAV2895
SAV_2895
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
2uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
29
Q6W5P6_9ACTO
(Q6W5P6)
Jump to FR008_00200
[query] 1 - 1740 (2034)
[subject] 6 - 1767 (9550)
(11 hsp)
0.0 1571   55%
Product
FscD
Gene
fscD
Organism
Streptomyces sp. FR-008
1uniprot[Pubmed] 14652074
Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003]
32
F1CLC1_9ACTO
(F1CLC1)
[query] 34 - 1738 (2034)
[subject] 3331 - 5012 (6831)
(5 hsp)
0.0 1563   54%
Product
ScnS1
Gene
scnS1
Organism
Streptomyces chattanoogensis
1uniprot[Pubmed] 21330439
The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011]
35
C3VLW8_9ACTO
(C3VLW8)
[query] 4 - 2029 (2034)
[subject] 5 - 1985 (1986)
0.0 1560   48%
Product
Polyketide synthase type I
Gene
becG
Organism
Streptomyces sp. DSM 21069
1uniprot[Pubmed] 19875084
Biosynthesis of macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit.(Chem. Biol.) [2009]
36
C6WNV0_ACTMD
(C6WNV0)
[query] 34 - 2029 (2034)
[subject] 3414 - 5400 (5400)
(3 hsp)
0.0 1558   49%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Amir_2684
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
37
Q9L4X2_9ACTO
(Q9L4X2)
Jump to Nysta_00060
[query] 36 - 1746 (2034)
[subject] 3636 - 5358 (5435)
(5 hsp)
0.0 1558   56%
Product
NysJ
Gene
nysJ
Organism
Streptomyces noursei
1uniprot[Pubmed] 10873841 [Medline] 20334850
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000]
38
D7BRD4_STRBB
(D7BRD4)
[query] 34 - 1758 (2034)
[subject] 2816 - 4590 (9950)
(7 hsp)
0.0 1556   53%
Product
Short-chain dehydrogenase/reductase SDR
Gene
SBI_01976
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
40
Q9X993_9ACTO
(Q9X993)
Jump to Pimar_00170
[query] 34 - 1738 (2034)
[subject] 3299 - 4978 (6797)
(5 hsp)
0.0 1549   54%
Product
PimS1 protein
Polyketide synthase
Gene
pimS1
Organism
Streptomyces natalensis
1uniprot[Pubmed] 10187796 [Medline] 99214571
The biosynthetic gene cluster for the 26-membered ring polyene macrolide pimaricin. A new polyketide synthase organization encoded by two subclusters separated by functionalization genes.(J. Biol. Chem.) [1999]
2uniprot[Pubmed] 11094342 [Medline] 20547809
A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000]
[pubmed all]
41
D7C2C3_STRBB
(D7C2C3)
[query] 1 - 1738 (2034)
[subject] 1 - 1849 (4868)
(5 hsp)
0.0 1548   51%
Product
Modular polyketide synthase
Gene
pks3-4
SBI_00656
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
43
C3VLZ6_9ACTO
(C3VLZ6)
[query] 4 - 2029 (2034)
[subject] 5 - 1991 (1992)
0.0 1546   47%
Product
Polyketide synthase type I
Gene
mlaG
Organism
Streptomyces sp. MP39-85
1uniprot[Pubmed] 19854930
Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010]
45
D2CKL6_PSEAH
(D2CKL6)
[query] 42 - 1746 (2034)
[subject] 3648 - 5348 (5425)
(5 hsp)
0.0 1545   56%
Product
CppJ
Gene
cppJ
Organism
Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
1uniprot[Pubmed] 19697072
Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009]
46
Q52V50_9ACTO
(Q52V50)
[query] 1 - 1763 (2034)
[subject] 6 - 1836 (7510)
(5 hsp)
0.0 1543   52%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
47
Q6JHN6_9PSEU
(Q6JHN6)
[query] 1 - 1764 (2034)
[subject] 30 - 1770 (7488)
(5 hsp)
0.0 1542   52%
Product
ObsC
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
48
Q52V46_9ACTO
(Q52V46)
[query] 2 - 1738 (2034)
[subject] 3181 - 4975 (8147)
(10 hsp)
0.0 1539   52%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
50
Q93NX9_9ACTO
(Q93NX9)
Jump to Amph_00040
[query] 1 - 1738 (2034)
[subject] 1 - 1752 (9510)
(11 hsp)
0.0 1534   53%
Product
AmphI
Gene
amphI
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
[pubmed all]