BLAST table : Amph_00170

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accessionDBtoolalignmentEvalueScoreIdent.linkproductgeneorganismec
1
Q93NW6_9ACTO
(Q93NW6)
[query] 1 - 10917 (10917)
[subject] 1 - 10917 (10917)
0.0 21370   100% AmphC amphC Streptomyces nodosus
2
Q9L4W3_9ACTO
(Q9L4W3)
Jump to Nysta_00150
[query] 1 - 10917 (10917)
[subject] 1 - 11096 (11096)
0.0 15300   75% NysC nysC Streptomyces noursei
3
D2CKM4_PSEAH
(D2CKM4)
[query] 1 - 10916 (10917)
[subject] 1 - 10875 (10876)
0.0 13630   71% CppC cppC Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
4
Q54296_STRHY
(Q54296)
Jump to Rapam_00110
[query] 6 - 10915 (10917)
[subject] 4 - 10219 (10223)
0.0 8715   49% Polyketide synthase rapB Streptomyces hygroscopicus
5
Q52V50_9ACTO
(Q52V50)
[query] 1762 - 9062 (10917)
[subject] 39 - 7428 (7510)
(8 hsp)
0.0 7496   58% Polyketide synthase type I Streptomyces aizunensis
6
Q6JHN6_9PSEU
(Q6JHN6)
[query] 1756 - 9061 (10917)
[subject] 57 - 7196 (7488)
(7 hsp)
0.0 7088   56% ObsC Saccharopolyspora spinosa
7
D7BRD4_STRBB
(D7BRD4)
[query] 5181 - 10917 (10917)
[subject] 4194 - 9950 (9950)
(16 hsp)
0.0 6377   63% Short-chain dehydrogenase/reductase SDR SBI_01976 Streptomyces bingchenggensis (strain BCW-1)
8
F1CLC1_9ACTO
(F1CLC1)
[query] 5195 - 10917 (10917)
[subject] 1201 - 6831 (6831)
(11 hsp)
0.0 6271   62% ScnS1 scnS1 Streptomyces chattanoogensis
9
Q9X993_9ACTO
(Q9X993)
Jump to Pimar_00170
[query] 5195 - 10917 (10917)
[subject] 1187 - 6797 (6797)
(11 hsp)
0.0 6209   62% PimS1 protein
Polyketide synthase
pimS1 Streptomyces natalensis
10
Q6MZA4_MYCUA
(Q6MZA4)
Jump to MUP_00400
[query] 37 - 8696 (10917)
[subject] 20 - 8973 (16990)
(19 hsp)
0.0 6200   44% Type I modular polyketide synthase mlsA1
MUP040c
Mycobacterium ulcerans (strain Agy99)
11
B6CLY8_9MYCO
(B6CLY8)
[query] 37 - 8696 (10917)
[subject] 20 - 8973 (17019)
(20 hsp)
0.0 6190   44% Type I modular polyketide synthase, MlsA1 mlsA1
MULP_065
Mycobacterium liflandii 128FXT
12
E0L044_STRVO
(E0L044)
[query] 5195 - 10902 (10917)
[subject] 1472 - 7209 (7224)
(7 hsp)
0.0 5979   59% Beta-ketoacyl synthase StrviDRAFT_8272 Streptomyces violaceusniger Tu 4113
13
Q6W5Q0_9ACTO
(Q6W5Q0)
Jump to FR008_00160
[query] 5213 - 10833 (10917)
[subject] 1431 - 6945 (10625)
(16 hsp)
0.0 5912   61% FscC fscC Streptomyces sp. FR-008
14
D7C2B8_STRBB
(D7C2B8)
[query] 2935 - 8694 (10917)
[subject] 988 - 6742 (7498)
(18 hsp)
0.0 5782   58% Type I modular polyketide synthase pks3-2
SBI_00651
Streptomyces bingchenggensis (strain BCW-1)
15
Q93NX8_9ACTO
(Q93NX8)
Jump to Amph_00050
[query] 1762 - 7301 (10917)
[subject] 39 - 5563 (5644)
(9 hsp)
0.0 5599   58% AmphJ amphJ Streptomyces nodosus
16
E3JBU2_FRASU
(E3JBU2)
[query] 1755 - 9061 (10917)
[subject] 28 - 7605 (7679)
(8 hsp)
0.0 5486   47% Acyl transferase FraEuI1c_4253 Frankia sp. (strain EuI1c)
17
E0L075_STRVO
(E0L075)
[query] 1762 - 6786 (10917)
[subject] 34 - 5098 (5786)
(13 hsp)
0.0 5440   60% Beta-ketoacyl synthase StrviDRAFT_8303 Streptomyces violaceusniger Tu 4113
18
Q82QT4_STRAW
(Q82QT4)
[query] 5195 - 10917 (10917)
[subject] 2173 - 7746 (7746)
(19 hsp)
0.0 5405   55% Modular polyketide synthase pteA1
SAV419
SAV_419
Streptomyces avermitilis
19
C0SMW4_9ACTO
(C0SMW4)
Jump to Tauto_00110
[query] 29 - 6452 (10917)
[subject] 3796 - 10159 (10827)
(29 hsp)
0.0 5383   51% Type I modular polyketide synthase ttmJ Streptomyces spiroverticillatus
20
Q54299_STRHY
(Q54299)
Jump to Rapam_00140
[query] 6 - 6451 (10917)
[subject] 5 - 6103 (6260)
(16 hsp)
0.0 5281   50% Polyketide synthase rapC Streptomyces hygroscopicus
21
Q52V52_9ACTO
(Q52V52)
[query] 5576 - 10917 (10917)
[subject] 35 - 5432 (5432)
(4 hsp)
0.0 5209   56% Polyketide synthase type I Streptomyces aizunensis
22
D9T6W4_MICAI
(D9T6W4)
[query] 5195 - 10860 (10917)
[subject] 1213 - 6846 (9936)
(26 hsp)
0.0 5102   54% Beta-ketoacyl synthase Micau_2464 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
23
E8S0C5_MICSL
(E8S0C5)
[query] 5195 - 10860 (10917)
[subject] 1213 - 6846 (9937)
(26 hsp)
0.0 5091   54% Beta-ketoacyl synthase ML5_5898 Micromonospora sp. (strain L5)
24
Q76KY0_STRHA
(Q76KY0)
Jump to Vicen_00200
[query] 3392 - 9072 (10917)
[subject] 25 - 5755 (5826)
(8 hsp)
0.0 5018   53% Polyketide synthase modules 1-3 vinP1 Streptomyces halstedii
25
Q0R4M5_STRAT
(Q0R4M5)
Jump to Chth_00290
[query] 3499 - 9066 (10917)
[subject] 32 - 5635 (5718)
(8 hsp)
0.0 5004   52% ChlA3 Streptomyces antibioticus
26
Q6JHN7_9PSEU
(Q6JHN7)
[query] 5574 - 10913 (10917)
[subject] 34 - 5176 (5176)
(9 hsp)
0.0 4902   54% ObsB Saccharopolyspora spinosa
27
C0SMW2_9ACTO
(C0SMW2)
Jump to Tauto_00090
[query] 1755 - 7297 (10917)
[subject] 28 - 5476 (5770)
(10 hsp)
0.0 4874   53% Type I modular polyketide synthase ttmH Streptomyces spiroverticillatus
28
A4X8L0_SALTO
(A4X8L0)
[query] 5214 - 10914 (10917)
[subject] 1549 - 7206 (7210)
(7 hsp)
0.0 4842   51% Beta-ketoacyl synthase Strop_2768 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
29
B4VDY6_9ACTO
(B4VDY6)
[query] 5573 - 10416 (10917)
[subject] 17 - 4843 (4894)
(6 hsp)
0.0 4815   57% Polyketide synthase type I SSAG_05828 Streptomyces sp. Mg1
30
C6WNW1_ACTMD
(C6WNW1)
[query] 5213 - 10914 (10917)
[subject] 1523 - 7106 (7110)
(9 hsp)
0.0 4807   52% Short-chain dehydrogenase/reductase SDR Amir_2695 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
31
C3VLY1_9ACTO
(C3VLY1)
[query] 5440 - 10917 (10917)
[subject] 891 - 6383 (6383)
(13 hsp)
0.0 4795   50% Polyketide synthase type I mlaA1 Streptomyces sp. MP39-85
32
D9VEY7_9ACTO
(D9VEY7)
[query] 5500 - 10871 (10917)
[subject] 55 - 5251 (5260)
(5 hsp)
0.0 4779   53% Modular polyketide synthase SSMG_05939 Streptomyces sp. AA4
33
C6WNV0_ACTMD
(C6WNV0)
[query] 5573 - 10833 (10917)
[subject] 37 - 5110 (5400)
(6 hsp)
0.0 4776   55% Short-chain dehydrogenase/reductase SDR Amir_2684 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
34
Q54297_STRHY
(Q54297)
Jump to Rapam_00120
[query] 1383 - 7298 (10917)
[subject] 2928 - 8487 (8563)
(17 hsp)
0.0 4746   50% Polyketide synthase rapA Streptomyces hygroscopicus
35
Q9ALM2_9PSEU
(Q9ALM2)
Jump to Spino_00210
[query] 5573 - 10835 (10917)
[subject] 32 - 5292 (5588)
(7 hsp)
0.0 4729   53% Polyketide synthase extender modules 8-10 spnE Saccharopolyspora spinosa
36
A1YAM7_AMYOR
(A1YAM7)
[query] 1760 - 6929 (10917)
[subject] 37 - 4949 (5723)
(15 hsp)
0.0 4709   55% Polyketide synthase type I Amycolatopsis orientalis
Nocardia orientalis
37
D6C477_9ACTO
(D6C477)
Jump to Meili_00310
[query] 3501 - 9061 (10917)
[subject] 39 - 5734 (5822)
(9 hsp)
0.0 4677   51% Modular polyketide synthase meiA3 Streptomyces nanchangensis
38
F8QPG0_9ACTO
(F8QPG0)
[query] 5574 - 10915 (10917)
[subject] 30 - 5320 (5321)
(7 hsp)
0.0 4640   53% Polyketide synthase natC Streptomyces sp. CS
39
D9T6W3_MICAI
(D9T6W3)
[query] 3124 - 8193 (10917)
[subject] 1726 - 6799 (7520)
(22 hsp)
0.0 4594   54% Acyl transferase Micau_2463 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
40
D7F1M1_9ACTO
(D7F1M1)
[query] 3500 - 9061 (10917)
[subject] 33 - 5547 (5630)
(9 hsp)
0.0 4583   49% Polyketide synthase tsnAIII Streptomyces longisporoflavus
41
E8S0C6_MICSL
(E8S0C6)
[query] 3124 - 8193 (10917)
[subject] 1726 - 6799 (7520)
(22 hsp)
0.0 4567   54% Beta-ketoacyl synthase ML5_5899 Micromonospora sp. (strain L5)
42
Q6JHN8_9PSEU
(Q6JHN8)
[query] 5481 - 10839 (10917)
[subject] 901 - 5980 (6078)
(13 hsp)
0.0 4562   53% ObsA Saccharopolyspora spinosa
43
C6ZCS1_9ACTO
(C6ZCS1)
[query] 35 - 5567 (10917)
[subject] 4141 - 9492 (9528)
(25 hsp)
0.0 4549   50% Type I modular polyketide synthase ttnA Streptomyces griseochromogenes
44
A4KCE4_9ACTO
(A4KCE4)
Jump to Tatmc_00080
[query] 35 - 5567 (10917)
[subject] 4257 - 9612 (9648)
(26 hsp)
0.0 4542   50% Tautomycetin biosynthetic PKS Streptomyces sp. CK4412
45
C6ZCS0_9ACTO
(C6ZCS0)
[query] 3120 - 8206 (10917)
[subject] 1689 - 6654 (7576)
(23 hsp)
0.0 4503   53% Type I modular polyketide synthase ttnB Streptomyces griseochromogenes
46
A4KCE5_9ACTO
(A4KCE5)
Jump to Tatmc_00090
[query] 3124 - 8206 (10917)
[subject] 1735 - 6698 (7620)
(23 hsp)
0.0 4496   53% Tautomycetin biosynthetic PKS Streptomyces sp. CK4412
47
B5L6K9_MICCH
(B5L6K9)
[query] 5199 - 10904 (10917)
[subject] 1378 - 6996 (7007)
(9 hsp)
0.0 4438   49% Putative type I polyketide synthase Micromonospora chalcea
48
F8QPF9_9ACTO
(F8QPF9)
[query] 5575 - 10916 (10917)
[subject] 35 - 5338 (5339)
(6 hsp)
0.0 4414   50% Polyketide synthase natB Streptomyces sp. CS
49
Q1MX73_9ACTO
(Q1MX73)
Jump to Tetrn_00160
[query] 3501 - 9057 (10917)
[subject] 34 - 5571 (5657)
(10 hsp)
0.0 4399   48% Type I polyketide synthase tmnAIV Streptomyces sp. NRRL 11266
50
A8J704_9ACTO
(A8J704)
[query] 3501 - 9050 (10917)
[subject] 38 - 5577 (5674)
(9 hsp)
0.0 4382   49% Modular polyketide synthase nemA3 Streptomyces cyaneogriseus subsp. noncyanogenus
accessionDBtoolalignmentEvalueScoreIdent.linkinformationpubmed
1
Q93NW6_9ACTO
(Q93NW6)
[query] 1 - 10917 (10917)
[subject] 1 - 10917 (10917)
0.0 21370   100%
Product
AmphC
Gene
amphC
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
[pubmed all]
2
Q9L4W3_9ACTO
(Q9L4W3)
Jump to Nysta_00150
[query] 1 - 10917 (10917)
[subject] 1 - 11096 (11096)
0.0 15300   75%
Product
NysC
Gene
nysC
Organism
Streptomyces noursei
1uniprot[Pubmed] 10873841 [Medline] 20334850
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000]
3
D2CKM4_PSEAH
(D2CKM4)
[query] 1 - 10916 (10917)
[subject] 1 - 10875 (10876)
0.0 13630   71%
Product
CppC
Gene
cppC
Organism
Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
1uniprot[Pubmed] 19697072
Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009]
4
Q54296_STRHY
(Q54296)
Jump to Rapam_00110
[query] 6 - 10915 (10917)
[subject] 4 - 10219 (10223)
0.0 8715   49%
Product
Polyketide synthase
Gene
rapB
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]
5
Q52V50_9ACTO
(Q52V50)
[query] 1762 - 9062 (10917)
[subject] 39 - 7428 (7510)
(8 hsp)
0.0 7496   58%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
6
Q6JHN6_9PSEU
(Q6JHN6)
[query] 1756 - 9061 (10917)
[subject] 57 - 7196 (7488)
(7 hsp)
0.0 7088   56%
Product
ObsC
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
7
D7BRD4_STRBB
(D7BRD4)
[query] 5181 - 10917 (10917)
[subject] 4194 - 9950 (9950)
(16 hsp)
0.0 6377   63%
Product
Short-chain dehydrogenase/reductase SDR
Gene
SBI_01976
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
8
F1CLC1_9ACTO
(F1CLC1)
[query] 5195 - 10917 (10917)
[subject] 1201 - 6831 (6831)
(11 hsp)
0.0 6271   62%
Product
ScnS1
Gene
scnS1
Organism
Streptomyces chattanoogensis
1uniprot[Pubmed] 21330439
The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011]
9
Q9X993_9ACTO
(Q9X993)
Jump to Pimar_00170
[query] 5195 - 10917 (10917)
[subject] 1187 - 6797 (6797)
(11 hsp)
0.0 6209   62%
Product
PimS1 protein
Polyketide synthase
Gene
pimS1
Organism
Streptomyces natalensis
1uniprot[Pubmed] 10187796 [Medline] 99214571
The biosynthetic gene cluster for the 26-membered ring polyene macrolide pimaricin. A new polyketide synthase organization encoded by two subclusters separated by functionalization genes.(J. Biol. Chem.) [1999]
2uniprot[Pubmed] 11094342 [Medline] 20547809
A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000]
[pubmed all]
10
Q6MZA4_MYCUA
(Q6MZA4)
Jump to MUP_00400
[query] 37 - 8696 (10917)
[subject] 20 - 8973 (16990)
(19 hsp)
0.0 6200   44%
Product
Type I modular polyketide synthase
Gene
mlsA1
MUP040c
Organism
Mycobacterium ulcerans (strain Agy99)
1uniprot[Pubmed] 15758215
Functional analysis and annotation of the virulence plasmid pMUM001 from Mycobacterium ulcerans.(Microbiology) [2005]
2uniprot[Pubmed] 14736915
Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans.(Proc. Natl. Acad. Sci. U.S.A.) [2004]
[pubmed all]
11
B6CLY8_9MYCO
(B6CLY8)
[query] 37 - 8696 (10917)
[subject] 20 - 8973 (17019)
(20 hsp)
0.0 6190   44%
Product
Type I modular polyketide synthase, MlsA1
Gene
mlsA1
MULP_065
Organism
Mycobacterium liflandii 128FXT
1uniprot[Pubmed] 18840298
Deciphering the genetic basis for polyketide variation among mycobacteria producing mycolactones.(BMC Genomics) [2008]
13
Q6W5Q0_9ACTO
(Q6W5Q0)
Jump to FR008_00160
[query] 5213 - 10833 (10917)
[subject] 1431 - 6945 (10625)
(16 hsp)
0.0 5912   61%
Product
FscC
Gene
fscC
Organism
Streptomyces sp. FR-008
1uniprot[Pubmed] 14652074
Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003]
14
D7C2B8_STRBB
(D7C2B8)
[query] 2935 - 8694 (10917)
[subject] 988 - 6742 (7498)
(18 hsp)
0.0 5782   58%
Product
Type I modular polyketide synthase
Gene
pks3-2
SBI_00651
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
15
Q93NX8_9ACTO
(Q93NX8)
Jump to Amph_00050
[query] 1762 - 7301 (10917)
[subject] 39 - 5563 (5644)
(9 hsp)
0.0 5599   58%
Product
AmphJ
Gene
amphJ
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
[pubmed all]
18
Q82QT4_STRAW
(Q82QT4)
[query] 5195 - 10917 (10917)
[subject] 2173 - 7746 (7746)
(19 hsp)
0.0 5405   55%
Product
Modular polyketide synthase
Gene
pteA1
SAV419
SAV_419
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
19
C0SMW4_9ACTO
(C0SMW4)
Jump to Tauto_00110
[query] 29 - 6452 (10917)
[subject] 3796 - 10159 (10827)
(29 hsp)
0.0 5383   51%
Product
Type I modular polyketide synthase
Gene
ttmJ
Organism
Streptomyces spiroverticillatus
1uniprot[Pubmed] 16707708
Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 18708355
Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008]
[pubmed all]
20
Q54299_STRHY
(Q54299)
Jump to Rapam_00140
[query] 6 - 6451 (10917)
[subject] 5 - 6103 (6260)
(16 hsp)
0.0 5281   50%
Product
Polyketide synthase
Gene
rapC
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]
21
Q52V52_9ACTO
(Q52V52)
[query] 5576 - 10917 (10917)
[subject] 35 - 5432 (5432)
(4 hsp)
0.0 5209   56%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
24
Q76KY0_STRHA
(Q76KY0)
Jump to Vicen_00200
[query] 3392 - 9072 (10917)
[subject] 25 - 5755 (5826)
(8 hsp)
0.0 5018   53%
Product
Polyketide synthase modules 1-3
Gene
vinP1
Organism
Streptomyces halstedii
1uniprot[Pubmed] 15112997
Cloning, sequencing, and functional analysis of the biosynthetic gene cluster of macrolactam antibiotic vicenistatin in Streptomyces halstedii.(Chem. Biol.) [2004]
25
Q0R4M5_STRAT
(Q0R4M5)
Jump to Chth_00290
[query] 3499 - 9066 (10917)
[subject] 32 - 5635 (5718)
(8 hsp)
0.0 5004   52%
Product
ChlA3
Gene
 
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 16793515
Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006]
26
Q6JHN7_9PSEU
(Q6JHN7)
[query] 5574 - 10913 (10917)
[subject] 34 - 5176 (5176)
(9 hsp)
0.0 4902   54%
Product
ObsB
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
27
C0SMW2_9ACTO
(C0SMW2)
Jump to Tauto_00090
[query] 1755 - 7297 (10917)
[subject] 28 - 5476 (5770)
(10 hsp)
0.0 4874   53%
Product
Type I modular polyketide synthase
Gene
ttmH
Organism
Streptomyces spiroverticillatus
1uniprot[Pubmed] 16707708
Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 18708355
Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008]
[pubmed all]
30
C6WNW1_ACTMD
(C6WNW1)
[query] 5213 - 10914 (10917)
[subject] 1523 - 7106 (7110)
(9 hsp)
0.0 4807   52%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Amir_2695
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
31
C3VLY1_9ACTO
(C3VLY1)
[query] 5440 - 10917 (10917)
[subject] 891 - 6383 (6383)
(13 hsp)
0.0 4795   50%
Product
Polyketide synthase type I
Gene
mlaA1
Organism
Streptomyces sp. MP39-85
1uniprot[Pubmed] 19854930
Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010]
33
C6WNV0_ACTMD
(C6WNV0)
[query] 5573 - 10833 (10917)
[subject] 37 - 5110 (5400)
(6 hsp)
0.0 4776   55%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Amir_2684
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
34
Q54297_STRHY
(Q54297)
Jump to Rapam_00120
[query] 1383 - 7298 (10917)
[subject] 2928 - 8487 (8563)
(17 hsp)
0.0 4746   50%
Product
Polyketide synthase
Gene
rapA
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]
35
Q9ALM2_9PSEU
(Q9ALM2)
Jump to Spino_00210
[query] 5573 - 10835 (10917)
[subject] 32 - 5292 (5588)
(7 hsp)
0.0 4729   53%
Product
Polyketide synthase extender modules 8-10
Gene
spnE
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 11358695 [Medline] 21257765
Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001]
36
A1YAM7_AMYOR
(A1YAM7)
[query] 1760 - 6929 (10917)
[subject] 37 - 4949 (5723)
(15 hsp)
0.0 4709   55%
Product
Polyketide synthase type I
Gene
 
Organism
Amycolatopsis orientalis
Nocardia orientalis
1uniprot[Pubmed] 17136886
Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006]
37
D6C477_9ACTO
(D6C477)
Jump to Meili_00310
[query] 3501 - 9061 (10917)
[subject] 39 - 5734 (5822)
(9 hsp)
0.0 4677   51%
Product
Modular polyketide synthase
Gene
meiA3
Organism
Streptomyces nanchangensis
1uniprot[Pubmed] 12811466 [Medline] 22777186
Identification of a gene cluster encoding meilingmycin biosynthesis among multiple polyketide synthase contigs isolated from Streptomyces nanchangensis NS3226.(Arch. Microbiol.) [2003]
2uniprot[Pubmed] 20348291
Cloning of separate meilingmycin biosynthesis gene clusters by use of acyltransferase-ketoreductase didomain PCR amplification.(Appl. Environ. Microbiol.) [2010]
[pubmed all]
38
F8QPG0_9ACTO
(F8QPG0)
[query] 5574 - 10915 (10917)
[subject] 30 - 5320 (5321)
(7 hsp)
0.0 4640   53%
Product
Polyketide synthase
Gene
natC
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
42
Q6JHN8_9PSEU
(Q6JHN8)
[query] 5481 - 10839 (10917)
[subject] 901 - 5980 (6078)
(13 hsp)
0.0 4562   53%
Product
ObsA
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
43
C6ZCS1_9ACTO
(C6ZCS1)
[query] 35 - 5567 (10917)
[subject] 4141 - 9492 (9528)
(25 hsp)
0.0 4549   50%
Product
Type I modular polyketide synthase
Gene
ttnA
Organism
Streptomyces griseochromogenes
1uniprot[Pubmed] 19191560
Characterization of the Tautomycetin Biosynthetic Gene Cluster from Streptomyces griseochromogenes Provides New Insight into Dialkylmaleic Anhydride Biosynthesis.(J. Nat. Prod.) [2009]
44
A4KCE4_9ACTO
(A4KCE4)
Jump to Tatmc_00080
[query] 35 - 5567 (10917)
[subject] 4257 - 9612 (9648)
(26 hsp)
0.0 4542   50%
Product
Tautomycetin biosynthetic PKS
Gene
 
Organism
Streptomyces sp. CK4412
1uniprot[Pubmed] 17379718
Isolation of the biosynthetic gene cluster for tautomycetin, a linear polyketide T cell-specific immunomodulator from Streptomyces sp. CK4412.(Microbiology) [2007]
45
C6ZCS0_9ACTO
(C6ZCS0)
[query] 3120 - 8206 (10917)
[subject] 1689 - 6654 (7576)
(23 hsp)
0.0 4503   53%
Product
Type I modular polyketide synthase
Gene
ttnB
Organism
Streptomyces griseochromogenes
1uniprot[Pubmed] 19191560
Characterization of the Tautomycetin Biosynthetic Gene Cluster from Streptomyces griseochromogenes Provides New Insight into Dialkylmaleic Anhydride Biosynthesis.(J. Nat. Prod.) [2009]
46
A4KCE5_9ACTO
(A4KCE5)
Jump to Tatmc_00090
[query] 3124 - 8206 (10917)
[subject] 1735 - 6698 (7620)
(23 hsp)
0.0 4496   53%
Product
Tautomycetin biosynthetic PKS
Gene
 
Organism
Streptomyces sp. CK4412
1uniprot[Pubmed] 17379718
Isolation of the biosynthetic gene cluster for tautomycetin, a linear polyketide T cell-specific immunomodulator from Streptomyces sp. CK4412.(Microbiology) [2007]
2uniprot[Pubmed] 20623733
Biochemical and structural characterization of the tautomycetin thioesterase: analysis of a stereoselective polyketide hydrolase.(Angew. Chem. Int. Ed.) [2010]
[pubmed all]
47
B5L6K9_MICCH
(B5L6K9)
[query] 5199 - 10904 (10917)
[subject] 1378 - 6996 (7007)
(9 hsp)
0.0 4438   49%
Product
Putative type I polyketide synthase
Gene
 
Organism
Micromonospora chalcea
1uniprot[Pubmed] 18586939
Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
48
F8QPF9_9ACTO
(F8QPF9)
[query] 5575 - 10916 (10917)
[subject] 35 - 5338 (5339)
(6 hsp)
0.0 4414   50%
Product
Polyketide synthase
Gene
natB
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]