BLAST table : Ansam_00100

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1
Q8KUF6_ACTPA
(Q8KUF6)
[query] 1 - 3324 (3324)
[subject] 1 - 3324 (3324)
0.0 6315   100% Polyketide synthase asmD Actinosynnema pretiosum subsp. auranticum
2
C6W870_ACTMD
(C6W870)
[query] 1 - 3324 (3324)
[subject] 1 - 3355 (3355)
0.0 5589   92% Acyl transferase Amir_3180 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
3
F8QPG0_9ACTO
(F8QPG0)
[query] 34 - 3311 (3324)
[subject] 1776 - 5235 (5321)
(5 hsp)
0.0 2457   49% Polyketide synthase natC Streptomyces sp. CS
4
E0L044_STRVO
(E0L044)
[query] 25 - 3312 (3324)
[subject] 1845 - 5343 (7224)
(10 hsp)
0.0 2383   47% Beta-ketoacyl synthase StrviDRAFT_8272 Streptomyces violaceusniger Tu 4113
5
Q9EX53_STRCO
(Q9EX53)
[query] 1 - 3311 (3324)
[subject] 1 - 3488 (3576)
(3 hsp)
0.0 2341   45% Putative type I polyketide synthase SCO6274 Streptomyces coelicolor
6
A4X8M0_SALTO
(A4X8M0)
[query] 1 - 3318 (3324)
[subject] 1 - 3431 (3711)
(3 hsp)
0.0 2286   46% Beta-ketoacyl synthase Strop_2778 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
7
A4FCY9_SACEN
(A4FCY9)
[query] 34 - 3315 (3324)
[subject] 1015 - 4526 (4576)
(8 hsp)
0.0 2193   44% Modular polyketide synthase SACE_2630 Saccharopolyspora erythraea (strain NRRL 23338)
8
D1XPI1_9ACTO
(D1XPI1)
[query] 34 - 3311 (3324)
[subject] 120 - 3523 (3603)
(4 hsp)
0.0 2192   47% Mycocerosate synthase, 6-deoxyerythronolide-B synthase SACTEDRAFT_4591 Streptomyces sp. SA3_actE 2.3.1.111

2.3.1.94
9
Q49BE0_STRHY
(Q49BE0)
Jump to Herb_00180
[query] 1 - 2584 (3324)
[subject] 1 - 2700 (3431)
(5 hsp)
0.0 2167   49% HbmAII hbmAII Streptomyces hygroscopicus
10
F1CT52_9ACTO
(F1CT52)
[query] 1 - 2584 (3324)
[subject] 1 - 2687 (3418)
(5 hsp)
0.0 2166   49% GdmAII gdmAII Streptomyces autolyticus
11
C6ZCS1_9ACTO
(C6ZCS1)
[query] 34 - 3322 (3324)
[subject] 4141 - 7450 (9528)
(14 hsp)
0.0 2154   45% Type I modular polyketide synthase ttnA Streptomyces griseochromogenes
12
Q84G23_STRHY
(Q84G23)
Jump to Gelda2_00090
[query] 1 - 2584 (3324)
[subject] 1 - 2702 (3435)
(6 hsp)
0.0 2149   48% GdmAII gdmAII Streptomyces hygroscopicus
13
Q1L0T1_STRHY
(Q1L0T1)
[query] 1 - 2584 (3324)
[subject] 1 - 2702 (3432)
(5 hsp)
0.0 2149   49% GelB Streptomyces hygroscopicus subsp. duamyceticus
14
D6AIT5_STRFL
(D6AIT5)
[query] 34 - 2585 (3324)
[subject] 1064 - 3664 (5541)
(8 hsp)
0.0 2142   50% Rifamycin polyketide synthase SSGG_00427 Streptomyces roseosporus NRRL 15998
15
D7BRE0_STRBB
(D7BRE0)
[query] 1 - 2832 (3324)
[subject] 1 - 2994 (3619)
(5 hsp)
0.0 2122   48% Modular polyketide synthase SBI_01982 Streptomyces bingchenggensis (strain BCW-1)
16
Q93NW6_9ACTO
(Q93NW6)
Jump to Amph_00170
[query] 27 - 2934 (3324)
[subject] 1755 - 4820 (10917)
(14 hsp)
0.0 2085   46% AmphC amphC Streptomyces nodosus
17
Q93HE5_STRAW
(Q93HE5)
[query] 34 - 2825 (3324)
[subject] 975 - 3922 (4498)
(7 hsp)
0.0 2073   47% Modular polyketide synthase
Putative modular polyketide synthase
pks5
SAV2368
SAV_2368
Streptomyces avermitilis
18
F8JUL0_STRCT
(F8JUL0)
[query] 34 - 2091 (3324)
[subject] 2732 - 4872 (5950)
(13 hsp)
0.0 2065   58% Putative polyketide synthase SCAT_3270 Streptomyces cattleya
19
D9WQ83_9ACTO
(D9WQ83)
[query] 1 - 2828 (3324)
[subject] 10 - 2960 (3002)
(3 hsp)
0.0 2050   46% Modular polyketide synthase SSOG_05757 Streptomyces himastatinicus ATCC 53653
20
A4FH85_SACEN
(A4FH85)
[query] 34 - 2091 (3324)
[subject] 1018 - 3166 (4327)
(11 hsp)
0.0 2050   57% Type I modular polyketide synthase SACE_4141 Saccharopolyspora erythraea (strain NRRL 23338)
21
Q5VKQ3_SACER
(Q5VKQ3)
[query] 34 - 2091 (3324)
[subject] 1018 - 3166 (4327)
(11 hsp)
0.0 2050   57% Type I PKS pkeAI Saccharopolyspora erythraea
Streptomyces erythraeus
22
C9YYI2_STRSW
(C9YYI2)
[query] 3 - 2090 (3324)
[subject] 7 - 2250 (3919)
(6 hsp)
0.0 2048   56% Putative type I polyketide synthase SCAB_83911 Streptomyces scabies (strain 87.22)
Streptomyces scabiei
23
C6WNW1_ACTMD
(C6WNW1)
[query] 34 - 2088 (3324)
[subject] 1882 - 4036 (7110)
(7 hsp)
0.0 2040   57% Short-chain dehydrogenase/reductase SDR Amir_2695 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
24
Q3S863_9ACTO
(Q3S863)
Jump to Conca_00070
[query] 3 - 2090 (3324)
[subject] 7 - 2246 (3982)
(9 hsp)
0.0 2037   56% Modular polyketide synthase Streptomyces neyagawaensis
25
Q0PCZ9_STRHA
(Q0PCZ9)
Jump to Halsto_00060
[query] 34 - 2583 (3324)
[subject] 1827 - 4504 (5232)
(9 hsp)
0.0 2035   50% Type I polyketide synthase hlsF Streptomyces halstedii
26
F1ADM0_9ACTO
(F1ADM0)
[query] 1 - 2089 (3324)
[subject] 1 - 2275 (3968)
(6 hsp)
0.0 2030   55% BafAIII Streptomyces lohii
27
Q9ALM3_9PSEU
(Q9ALM3)
Jump to Spino_00200
[query] 1 - 2583 (3324)
[subject] 5 - 2672 (4928)
(9 hsp)
0.0 2024   49% Polyketide synthase extender modules 5-7 spnD Saccharopolyspora spinosa
28
Q9L4W3_9ACTO
(Q9L4W3)
Jump to Nysta_00150
[query] 34 - 2864 (3324)
[subject] 1757 - 4700 (11096)
(16 hsp)
0.0 2020   47% NysC nysC Streptomyces noursei
29
Q0PD02_STRHA
(Q0PD02)
Jump to Halsto_00030
[query] 33 - 2827 (3324)
[subject] 1592 - 4546 (5220)
(10 hsp)
0.0 2020   47% Type I polyketide synthase hlsC Streptomyces halstedii
30
E0D206_9ACTO
(E0D206)
Jump to FD891_00050
[query] 1 - 2082 (3324)
[subject] 1 - 2175 (3799)
(4 hsp)
0.0 2016   55% Polyketide synthase gfsE Streptomyces graminofaciens
31
E0KBI2_STRVO
(E0KBI2)
[query] 1 - 2088 (3324)
[subject] 1 - 2193 (4930)
(10 hsp)
0.0 2007   55% Mycocerosate synthase., 6-deoxyerythronolide-B synthase StrviDRAFT_0197 Streptomyces violaceusniger Tu 4113 2.3.1.111

2.3.1.94
32
A0FCL2_STRVO
(A0FCL2)
Jump to Merid_00030
[query] 1 - 2583 (3324)
[subject] 1 - 2628 (7178)
(11 hsp)
0.0 2004   49% MerB merB Streptomyces violaceoniger
33
E4NJF3_KITSK
(E4NJF3)
[query] 1 - 2094 (3324)
[subject] 1 - 2269 (3964)
(6 hsp)
0.0 1999   55% Modular polyketide synthase BFAS3 bfmA3
KSE_73460
Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
34
E8WEN9_STRFA
(E8WEN9)
[query] 5 - 2083 (3324)
[subject] 6 - 2171 (3511)
(4 hsp)
0.0 1998   56% Mycocerosate synthase, 6-deoxyerythronolide-B synthase Sfla_0983 Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD) 2.3.1.111

2.3.1.94
35
E0KBI0_STRVO
(E0KBI0)
[query] 2 - 2083 (3324)
[subject] 5 - 2202 (3955)
(6 hsp)
0.0 1994   54% Acyl transferase StrviDRAFT_0195 Streptomyces violaceusniger Tu 4113
36
D8HZ83_AMYMU
(D8HZ83)
[query] 4 - 2083 (3324)
[subject] 5 - 2142 (5060)
(6 hsp)
0.0 1986   55% Rifamycin polyketide synthase rifB
AMED_0618
Amycolatopsis mediterranei (strain U-32)
37
O52545_AMYMD
(O52545)
Jump to Rifam_00220
[query] 4 - 2083 (3324)
[subject] 5 - 2142 (5060)
(6 hsp)
0.0 1986   55% RifB rifB Amycolatopsis mediterranei
Nocardia mediterranei
38
O52789_AMYMD
(O52789)
[query] 4 - 2083 (3324)
[subject] 14 - 2151 (5069)
(6 hsp)
0.0 1982   55% Rifamycin polyketide synthase, type 1 Amycolatopsis mediterranei
Nocardia mediterranei
39
A8M6C7_SALAI
(A8M6C7)
[query] 4 - 2083 (3324)
[subject] 5 - 2181 (5255)
(6 hsp)
0.0 1982   55% Beta-ketoacyl synthase Sare_1247 Salinispora arenicola (strain CNS-205)
40
E9KTB4_STRKN
(E9KTB4)
[query] 5 - 2788 (3324)
[subject] 4 - 2685 (3597)
(5 hsp)
0.0 1978   48% Polyketide synthase fkbC
Tcs_SK_030
Streptomyces kanamyceticus
41
F8QPF9_9ACTO
(F8QPF9)
[query] 4 - 2093 (3324)
[subject] 5 - 2223 (5339)
(6 hsp)
0.0 1972   54% Polyketide synthase natB Streptomyces sp. CS
42
Q9ALM2_9PSEU
(Q9ALM2)
Jump to Spino_00210
[query] 1 - 2094 (3324)
[subject] 1 - 2222 (5588)
(7 hsp)
0.0 1969   53% Polyketide synthase extender modules 8-10 spnE Saccharopolyspora spinosa
43
Q68BG4_STRHA
(Q68BG4)
Jump to Halsto_00020
[query] 34 - 2083 (3324)
[subject] 1580 - 3782 (7111)
(15 hsp)
0.0 1969   54% Type I polyketide synthase hlsB Streptomyces halstedii
44
A8LUX2_SALAI
(A8LUX2)
[query] 34 - 2093 (3324)
[subject] 2666 - 4816 (7279)
(17 hsp)
0.0 1967   54% Beta-ketoacyl synthase Sare_3156 Salinispora arenicola (strain CNS-205)
45
A4X8L0_SALTO
(A4X8L0)
[query] 27 - 2081 (3324)
[subject] 3636 - 5807 (7210)
(10 hsp)
0.0 1967   54% Beta-ketoacyl synthase Strop_2768 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
46
Q1L0S8_STRHY
(Q1L0S8)
[query] 18 - 2812 (3324)
[subject] 1068 - 3907 (5683)
(11 hsp)
0.0 1963   46% NapA Streptomyces hygroscopicus subsp. duamyceticus
47
E0L075_STRVO
(E0L075)
[query] 1 - 2083 (3324)
[subject] 1 - 2228 (5786)
(11 hsp)
0.0 1962   53% Beta-ketoacyl synthase StrviDRAFT_8303 Streptomyces violaceusniger Tu 4113
48
C6ZCS0_9ACTO
(C6ZCS0)
[query] 34 - 2591 (3324)
[subject] 4077 - 6654 (7576)
(11 hsp)
0.0 1952   49% Type I modular polyketide synthase ttnB Streptomyces griseochromogenes
49
Q1WEK8_9ACTO
(Q1WEK8)
[query] 1 - 2083 (3324)
[subject] 1 - 2156 (7102)
(13 hsp)
0.0 1942   54% Polyketide synthase merB Streptomyces sp. NRRL 30748
50
C3VLW9_9ACTO
(C3VLW9)
[query] 2 - 2088 (3324)
[subject] 5 - 2128 (3377)
(4 hsp)
0.0 1941   53% Polyketide synthase type I becF Streptomyces sp. DSM 21069
accessionDBtoolalignmentEvalueScoreIdent.linkinformationpubmed
1
Q8KUF6_ACTPA
(Q8KUF6)
[query] 1 - 3324 (3324)
[subject] 1 - 3324 (3324)
0.0 6315   100%
Product
Polyketide synthase
Gene
asmD
Organism
Actinosynnema pretiosum subsp. auranticum
1uniprot[Pubmed] 12060743 [Medline] 22056096
The biosynthetic gene cluster of the maytansinoid antitumor agent ansamitocin from Actinosynnema pretiosum.(Proc. Natl. Acad. Sci. U.S.A.) [2002]
2
C6W870_ACTMD
(C6W870)
[query] 1 - 3324 (3324)
[subject] 1 - 3355 (3355)
0.0 5589   92%
Product
Acyl transferase
Gene
Amir_3180
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
3
F8QPG0_9ACTO
(F8QPG0)
[query] 34 - 3311 (3324)
[subject] 1776 - 5235 (5321)
(5 hsp)
0.0 2457   49%
Product
Polyketide synthase
Gene
natC
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
5
Q9EX53_STRCO
(Q9EX53)
[query] 1 - 3311 (3324)
[subject] 1 - 3488 (3576)
(3 hsp)
0.0 2341   45%
Product
Putative type I polyketide synthase
Gene
SCO6274
Organism
Streptomyces coelicolor
1uniprot[Pubmed] 12000953 [Medline] 21996410
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002]
7
A4FCY9_SACEN
(A4FCY9)
[query] 34 - 3315 (3324)
[subject] 1015 - 4526 (4576)
(8 hsp)
0.0 2193   44%
Product
Modular polyketide synthase
Gene
SACE_2630
Organism
Saccharopolyspora erythraea (strain NRRL 23338)
1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
9
Q49BE0_STRHY
(Q49BE0)
Jump to Herb_00180
[query] 1 - 2584 (3324)
[subject] 1 - 2700 (3431)
(5 hsp)
0.0 2167   49%
Product
HbmAII
Gene
hbmAII
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 16085885
Insights into the biosynthesis of the benzoquinone ansamycins geldanamycin and herbimycin, obtained by gene sequencing and disruption.(Appl. Environ. Microbiol.) [2005]
10
F1CT52_9ACTO
(F1CT52)
[query] 1 - 2584 (3324)
[subject] 1 - 2687 (3418)
(5 hsp)
0.0 2166   49%
Product
GdmAII
Gene
gdmAII
Organism
Streptomyces autolyticus
1uniprot[Pubmed] 21544574
Streptomyces autolyticus JX-47 Large-Insert Bacterial Artificial Chromosome Library Construction and Identification of Clones Covering Geldanamycin Biosynthesis Gene Cluster.(Curr. Microbiol.) [2011]
11
C6ZCS1_9ACTO
(C6ZCS1)
[query] 34 - 3322 (3324)
[subject] 4141 - 7450 (9528)
(14 hsp)
0.0 2154   45%
Product
Type I modular polyketide synthase
Gene
ttnA
Organism
Streptomyces griseochromogenes
1uniprot[Pubmed] 19191560
Characterization of the Tautomycetin Biosynthetic Gene Cluster from Streptomyces griseochromogenes Provides New Insight into Dialkylmaleic Anhydride Biosynthesis.(J. Nat. Prod.) [2009]
12
Q84G23_STRHY
(Q84G23)
Jump to Gelda2_00090
[query] 1 - 2584 (3324)
[subject] 1 - 2702 (3435)
(6 hsp)
0.0 2149   48%
Product
GdmAII
Gene
gdmAII
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 12586396 [Medline] 22474162
Cloning and characterization of a gene cluster for geldanamycin production in Streptomyces hygroscopicus NRRL 3602.(FEMS Microbiol. Lett.) [2003]
13
Q1L0T1_STRHY
(Q1L0T1)
[query] 1 - 2584 (3324)
[subject] 1 - 2702 (3432)
(5 hsp)
0.0 2149   49%
Product
GelB
Gene
 
Organism
Streptomyces hygroscopicus subsp. duamyceticus
1uniprot[Pubmed] 18600054
Characterization of tailoring genes involved in the modification of geldanamycin polyketide in Streptomyces hygroscopicus JCM4427.(J. Microbiol. Biotechnol.) [2008]
15
D7BRE0_STRBB
(D7BRE0)
[query] 1 - 2832 (3324)
[subject] 1 - 2994 (3619)
(5 hsp)
0.0 2122   48%
Product
Modular polyketide synthase
Gene
SBI_01982
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
16
Q93NW6_9ACTO
(Q93NW6)
Jump to Amph_00170
[query] 27 - 2934 (3324)
[subject] 1755 - 4820 (10917)
(14 hsp)
0.0 2085   46%
Product
AmphC
Gene
amphC
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
[pubmed all]
17
Q93HE5_STRAW
(Q93HE5)
[query] 34 - 2825 (3324)
[subject] 975 - 3922 (4498)
(7 hsp)
0.0 2073   47%
Product
Modular polyketide synthase
Putative modular polyketide synthase
Gene
pks5
SAV2368
SAV_2368
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
2uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
20
A4FH85_SACEN
(A4FH85)
[query] 34 - 2091 (3324)
[subject] 1018 - 3166 (4327)
(11 hsp)
0.0 2050   57%
Product
Type I modular polyketide synthase
Gene
SACE_4141
Organism
Saccharopolyspora erythraea (strain NRRL 23338)
1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
21
Q5VKQ3_SACER
(Q5VKQ3)
[query] 34 - 2091 (3324)
[subject] 1018 - 3166 (4327)
(11 hsp)
0.0 2050   57%
Product
Type I PKS
Gene
pkeAI
Organism
Saccharopolyspora erythraea
Streptomyces erythraeus
1uniprot[Pubmed] 15925898
A new modular polyketide synthase in the erythromycin producer Saccharopolyspora erythraea.(J. Mol. Microbiol. Biotechnol.) [2004]
22
C9YYI2_STRSW
(C9YYI2)
[query] 3 - 2090 (3324)
[subject] 7 - 2250 (3919)
(6 hsp)
0.0 2048   56%
Product
Putative type I polyketide synthase
Gene
SCAB_83911
Organism
Streptomyces scabies (strain 87.22)
Streptomyces scabiei
1uniprot[Pubmed] 20064060
Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010]
23
C6WNW1_ACTMD
(C6WNW1)
[query] 34 - 2088 (3324)
[subject] 1882 - 4036 (7110)
(7 hsp)
0.0 2040   57%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Amir_2695
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
24
Q3S863_9ACTO
(Q3S863)
Jump to Conca_00070
[query] 3 - 2090 (3324)
[subject] 7 - 2246 (3982)
(9 hsp)
0.0 2037   56%
Product
Modular polyketide synthase
Gene
 
Organism
Streptomyces neyagawaensis
1uniprot[Pubmed] 16207901
Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005]
27
Q9ALM3_9PSEU
(Q9ALM3)
Jump to Spino_00200
[query] 1 - 2583 (3324)
[subject] 5 - 2672 (4928)
(9 hsp)
0.0 2024   49%
Product
Polyketide synthase extender modules 5-7
Gene
spnD
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 11358695 [Medline] 21257765
Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001]
28
Q9L4W3_9ACTO
(Q9L4W3)
Jump to Nysta_00150
[query] 34 - 2864 (3324)
[subject] 1757 - 4700 (11096)
(16 hsp)
0.0 2020   47%
Product
NysC
Gene
nysC
Organism
Streptomyces noursei
1uniprot[Pubmed] 10873841 [Medline] 20334850
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000]
30
E0D206_9ACTO
(E0D206)
Jump to FD891_00050
[query] 1 - 2082 (3324)
[subject] 1 - 2175 (3799)
(4 hsp)
0.0 2016   55%
Product
Polyketide synthase
Gene
gfsE
Organism
Streptomyces graminofaciens
1uniprot[Pubmed] 20589823
Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010]
32
A0FCL2_STRVO
(A0FCL2)
Jump to Merid_00030
[query] 1 - 2583 (3324)
[subject] 1 - 2628 (7178)
(11 hsp)
0.0 2004   49%
Product
MerB
Gene
merB
Organism
Streptomyces violaceoniger
1uniprot[Pubmed] 17159202
Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006]
33
E4NJF3_KITSK
(E4NJF3)
[query] 1 - 2094 (3324)
[subject] 1 - 2269 (3964)
(6 hsp)
0.0 1999   55%
Product
Modular polyketide synthase BFAS3
Gene
bfmA3
KSE_73460
Organism
Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
1uniprot[Pubmed] 21059706
Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010]
36
D8HZ83_AMYMU
(D8HZ83)
[query] 4 - 2083 (3324)
[subject] 5 - 2142 (5060)
(6 hsp)
0.0 1986   55%
Product
Rifamycin polyketide synthase
Gene
rifB
AMED_0618
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
37
O52545_AMYMD
(O52545)
Jump to Rifam_00220
[query] 4 - 2083 (3324)
[subject] 5 - 2142 (5060)
(6 hsp)
0.0 1986   55%
Product
RifB
Gene
rifB
Organism
Amycolatopsis mediterranei
Nocardia mediterranei
1uniprot[Pubmed] 9512878 [Medline] 98174059
Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.(Chem. Biol.) [1998]
2uniprot[Pubmed] 9497318 [Medline] 98165773
3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.(J. Biol. Chem.) [1998]
3uniprot[Pubmed] 11278540 [Medline] 21201076
Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.(J. Biol. Chem.) [2001]
[pubmed all]
40
E9KTB4_STRKN
(E9KTB4)
[query] 5 - 2788 (3324)
[subject] 4 - 2685 (3597)
(5 hsp)
0.0 1978   48%
Product
Polyketide synthase
Gene
fkbC
Tcs_SK_030
Organism
Streptomyces kanamyceticus
1uniprot[Pubmed] 21175203
Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.(J. Am. Chem. Soc.) [2011]
41
F8QPF9_9ACTO
(F8QPF9)
[query] 4 - 2093 (3324)
[subject] 5 - 2223 (5339)
(6 hsp)
0.0 1972   54%
Product
Polyketide synthase
Gene
natB
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
42
Q9ALM2_9PSEU
(Q9ALM2)
Jump to Spino_00210
[query] 1 - 2094 (3324)
[subject] 1 - 2222 (5588)
(7 hsp)
0.0 1969   53%
Product
Polyketide synthase extender modules 8-10
Gene
spnE
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 11358695 [Medline] 21257765
Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001]
43
Q68BG4_STRHA
(Q68BG4)
Jump to Halsto_00020
[query] 34 - 2083 (3324)
[subject] 1580 - 3782 (7111)
(15 hsp)
0.0 1969   54%
Product
Type I polyketide synthase
Gene
hlsB
Organism
Streptomyces halstedii
1uniprot
Genome-inspired search for new antibiotics; Isolation and structure determination of new 28-membered polyketide macrolactones, halstoctacosanolides A and B, from Streptomyces halstedii HC34.(Tetrahedron) [2004]
48
C6ZCS0_9ACTO
(C6ZCS0)
[query] 34 - 2591 (3324)
[subject] 4077 - 6654 (7576)
(11 hsp)
0.0 1952   49%
Product
Type I modular polyketide synthase
Gene
ttnB
Organism
Streptomyces griseochromogenes
1uniprot[Pubmed] 19191560
Characterization of the Tautomycetin Biosynthetic Gene Cluster from Streptomyces griseochromogenes Provides New Insight into Dialkylmaleic Anhydride Biosynthesis.(J. Nat. Prod.) [2009]
49
Q1WEK8_9ACTO
(Q1WEK8)
[query] 1 - 2083 (3324)
[subject] 1 - 2156 (7102)
(13 hsp)
0.0 1942   54%
Product
Polyketide synthase
Gene
merB
Organism
Streptomyces sp. NRRL 30748
1uniprot[Pubmed] 16806745
Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006]
50
C3VLW9_9ACTO
(C3VLW9)
[query] 2 - 2088 (3324)
[subject] 5 - 2128 (3377)
(4 hsp)
0.0 1941   53%
Product
Polyketide synthase type I
Gene
becF
Organism
Streptomyces sp. DSM 21069
1uniprot[Pubmed] 19875084
Biosynthesis of macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit.(Chem. Biol.) [2009]