BLAST table : Ansam_00280

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1
Q8KUH4_ACTPA
(Q8KUH4)
[query] 1 - 3073 (3073)
[subject] 1 - 3073 (3073)
0.0 5775   100% Polyketide synthase asmB Actinosynnema pretiosum subsp. auranticum
2
C6W8L0_ACTMD
(C6W8L0)
[query] 564 - 3072 (3073)
[subject] 617 - 3147 (3148)
0.0 4180   94% Acyl transferase Amir_3198 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
3
B4VDY6_9ACTO
(B4VDY6)
[query] 29 - 2629 (3073)
[subject] 19 - 2637 (4894)
(6 hsp)
0.0 2162   51% Polyketide synthase type I SSAG_05828 Streptomyces sp. Mg1
4
Q9ALM2_9PSEU
(Q9ALM2)
Jump to Spino_00210
[query] 1 - 2629 (3073)
[subject] 1 - 2666 (5588)
(7 hsp)
0.0 2133   49% Polyketide synthase extender modules 8-10 spnE Saccharopolyspora spinosa
5
D6AIT5_STRFL
(D6AIT5)
[query] 26 - 2629 (3073)
[subject] 1061 - 3659 (5541)
(9 hsp)
0.0 2131   51% Rifamycin polyketide synthase SSGG_00427 Streptomyces roseosporus NRRL 15998
6
C3VLW9_9ACTO
(C3VLW9)
[query] 2 - 2629 (3073)
[subject] 5 - 2521 (3377)
(4 hsp)
0.0 2129   50% Polyketide synthase type I becF Streptomyces sp. DSM 21069
7
Q30CR9_STRAU
(Q30CR9)
Jump to Alip_00160
[query] 2 - 2629 (3073)
[subject] 3 - 2632 (3277)
(5 hsp)
0.0 2126   49% LipPks4 lipPks4 Streptomyces aureofaciens
8
A4X8L0_SALTO
(A4X8L0)
[query] 29 - 2629 (3073)
[subject] 3643 - 6278 (7210)
(11 hsp)
0.0 2125   50% Beta-ketoacyl synthase Strop_2768 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
9
C3VLZ7_9ACTO
(C3VLZ7)
[query] 8 - 2629 (3073)
[subject] 21 - 2519 (3373)
(5 hsp)
0.0 2125   50% Polyketide synthase type I mlaF Streptomyces sp. MP39-85
10
C6WNW1_ACTMD
(C6WNW1)
[query] 29 - 2629 (3073)
[subject] 3599 - 6201 (7110)
(11 hsp)
0.0 2124   51% Short-chain dehydrogenase/reductase SDR Amir_2695 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
11
Q82QT4_STRAW
(Q82QT4)
[query] 23 - 2629 (3073)
[subject] 4280 - 6826 (7746)
(16 hsp)
0.0 2124   50% Modular polyketide synthase pteA1
SAV419
SAV_419
Streptomyces avermitilis
12
F8QPG0_9ACTO
(F8QPG0)
[query] 29 - 2629 (3073)
[subject] 1776 - 4406 (5321)
(6 hsp)
0.0 2120   50% Polyketide synthase natC Streptomyces sp. CS
13
Q0R4M8_STRAT
(Q0R4M8)
Jump to Chth_00260
[query] 3 - 2629 (3073)
[subject] 1055 - 3765 (4699)
(8 hsp)
0.0 2119   50% ChlA1 Streptomyces antibioticus
14
D9WQL2_9ACTO
(D9WQL2)
[query] 5 - 2633 (3073)
[subject] 6 - 2496 (3284)
(4 hsp)
0.0 2108   50% Modular polyketide synthase SSOG_07859 Streptomyces himastatinicus ATCC 53653
15
E8WEN9_STRFA
(E8WEN9)
[query] 2 - 2629 (3073)
[subject] 3 - 2611 (3511)
(4 hsp)
0.0 2104   50% Mycocerosate synthase, 6-deoxyerythronolide-B synthase Sfla_0983 Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD) 2.3.1.111

2.3.1.94
16
Q52V49_9ACTO
(Q52V49)
[query] 7 - 2629 (3073)
[subject] 9 - 2672 (3872)
(5 hsp)
0.0 2102   49% Polyketide synthase type I Streptomyces aizunensis
17
Q0S8W4_RHOSR
(Q0S8W4)
[query] 1 - 2632 (3073)
[subject] 1 - 2631 (3527)
(5 hsp)
0.0 2101   49% Type I polyketide synthase RHA1_ro04231 Rhodococcus sp. (strain RHA1)
18
C1B9P9_RHOOB
(C1B9P9)
[query] 1 - 2632 (3073)
[subject] 1 - 2633 (3527)
(6 hsp)
0.0 2101   48% Polyketide synthase ROP_41550 Rhodococcus opacus (strain B4)
19
D9WQ64_9ACTO
(D9WQ64)
[query] 23 - 2629 (3073)
[subject] 990 - 3635 (3874)
(7 hsp)
0.0 2099   48% Modular polyketide synthase SSOG_05738 Streptomyces himastatinicus ATCC 53653
20
C0SMW4_9ACTO
(C0SMW4)
Jump to Tauto_00110
[query] 18 - 2630 (3073)
[subject] 552 - 3154 (10827)
(18 hsp)
0.0 2096   50% Type I modular polyketide synthase ttmJ Streptomyces spiroverticillatus
21
F1CT52_9ACTO
(F1CT52)
[query] 1 - 2629 (3073)
[subject] 1 - 2683 (3418)
(5 hsp)
0.0 2092   47% GdmAII gdmAII Streptomyces autolyticus
22
C9YYI2_STRSW
(C9YYI2)
[query] 29 - 2629 (3073)
[subject] 38 - 2682 (3919)
(5 hsp)
0.0 2087   50% Putative type I polyketide synthase SCAB_83911 Streptomyces scabies (strain 87.22)
Streptomyces scabiei
23
Q6JHN6_9PSEU
(Q6JHN6)
[query] 29 - 2632 (3073)
[subject] 3768 - 6361 (7488)
(9 hsp)
0.0 2086   51% ObsC Saccharopolyspora spinosa
24
F8QPF9_9ACTO
(F8QPF9)
[query] 29 - 2629 (3073)
[subject] 1786 - 4409 (5339)
(7 hsp)
0.0 2085   49% Polyketide synthase natB Streptomyces sp. CS
25
Q9ALM3_9PSEU
(Q9ALM3)
Jump to Spino_00200
[query] 1 - 2629 (3073)
[subject] 5 - 2669 (4928)
(9 hsp)
0.0 2084   49% Polyketide synthase extender modules 5-7 spnD Saccharopolyspora spinosa
26
A8LUX2_SALAI
(A8LUX2)
[query] 27 - 2632 (3073)
[subject] 2664 - 5201 (7279)
(14 hsp)
0.0 2083   50% Beta-ketoacyl synthase Sare_3156 Salinispora arenicola (strain CNS-205)
27
D8HZ82_AMYMU
(D8HZ82)
[query] 29 - 2629 (3073)
[subject] 632 - 3054 (4735)
(11 hsp)
0.0 2082   51% Rifamycin polyketide synthase rifA
AMED_0617
Amycolatopsis mediterranei (strain U-32)
28
O54666_AMYMD
(O54666)
Jump to Rifam_00210
[query] 29 - 2629 (3073)
[subject] 632 - 3054 (4735)
(11 hsp)
0.0 2082   51% RifA
Rifamycin polyketide synthase, type 1
rifA Amycolatopsis mediterranei
Nocardia mediterranei
29
E0KBI2_STRVO
(E0KBI2)
[query] 29 - 2629 (3073)
[subject] 33 - 2640 (4930)
(7 hsp)
0.0 2082   49% Mycocerosate synthase., 6-deoxyerythronolide-B synthase StrviDRAFT_0197 Streptomyces violaceusniger Tu 4113 2.3.1.111

2.3.1.94
30
Q1WEK9_9ACTO
(Q1WEK9)
[query] 29 - 2629 (3073)
[subject] 2523 - 5049 (5712)
(11 hsp)
0.0 2079   51% Polyketide synthase merA Streptomyces sp. NRRL 30748
31
D7F1M1_9ACTO
(D7F1M1)
[query] 29 - 2558 (3073)
[subject] 2094 - 4641 (5630)
(8 hsp)
0.0 2075   48% Polyketide synthase tsnAIII Streptomyces longisporoflavus
32
C3VLZ4_9ACTO
(C3VLZ4)
[query] 5 - 2637 (3073)
[subject] 6 - 2493 (3365)
(4 hsp)
0.0 2075   50% Polyketide synthase type I mlaD Streptomyces sp. MP39-85
33
D9VBL5_9ACTO
(D9VBL5)
[query] 31 - 2629 (3073)
[subject] 984 - 3492 (5113)
(12 hsp)
0.0 2073   50% Modular polyketide synthase SSMG_01148 Streptomyces sp. AA4
34
F1CLC1_9ACTO
(F1CLC1)
[query] 29 - 2631 (3073)
[subject] 1578 - 4202 (6831)
(10 hsp)
0.0 2071   49% ScnS1 scnS1 Streptomyces chattanoogensis
35
Q6JHN7_9PSEU
(Q6JHN7)
[query] 29 - 2630 (3073)
[subject] 1723 - 4280 (5176)
(7 hsp)
0.0 2071   50% ObsB Saccharopolyspora spinosa
36
F1ADM0_9ACTO
(F1ADM0)
[query] 1 - 2629 (3073)
[subject] 1 - 2716 (3968)
(6 hsp)
0.0 2068   49% BafAIII Streptomyces lohii
37
E0KBI0_STRVO
(E0KBI0)
[query] 2 - 2637 (3073)
[subject] 5 - 2666 (3955)
(6 hsp)
0.0 2063   48% Acyl transferase StrviDRAFT_0195 Streptomyces violaceusniger Tu 4113
38
O52545_AMYMD
(O52545)
Jump to Rifam_00220
[query] 4 - 2629 (3073)
[subject] 5 - 2573 (5060)
(8 hsp)
0.0 2062   49% RifB rifB Amycolatopsis mediterranei
Nocardia mediterranei
39
D8HZ83_AMYMU
(D8HZ83)
[query] 4 - 2629 (3073)
[subject] 5 - 2573 (5060)
(8 hsp)
0.0 2061   49% Rifamycin polyketide synthase rifB
AMED_0618
Amycolatopsis mediterranei (strain U-32)
40
A8M6C6_SALAI
(A8M6C6)
[query] 29 - 2629 (3073)
[subject] 638 - 3182 (5154)
(10 hsp)
0.0 2060   50% AMP-dependent synthetase and ligase Sare_1246 Salinispora arenicola (strain CNS-205)
41
Q3S863_9ACTO
(Q3S863)
Jump to Conca_00070
[query] 16 - 2627 (3073)
[subject] 24 - 2671 (3982)
(6 hsp)
0.0 2060   49% Modular polyketide synthase Streptomyces neyagawaensis
42
E8S0C5_MICSL
(E8S0C5)
[query] 5 - 2630 (3073)
[subject] 5071 - 7720 (9937)
(15 hsp)
0.0 2059   49% Beta-ketoacyl synthase ML5_5898 Micromonospora sp. (strain L5)
43
D9W5N3_9ACTO
(D9W5N3)
[query] 29 - 2637 (3073)
[subject] 603 - 3229 (4488)
(9 hsp)
0.0 2058   50% Lasalocid modular polyketide synthase SSNG_07463 Streptomyces sp. C
44
O52789_AMYMD
(O52789)
[query] 4 - 2629 (3073)
[subject] 14 - 2582 (5069)
(8 hsp)
0.0 2056   49% Rifamycin polyketide synthase, type 1 Amycolatopsis mediterranei
Nocardia mediterranei
45
Q9X993_9ACTO
(Q9X993)
Jump to Pimar_00170
[query] 23 - 2631 (3073)
[subject] 1556 - 4170 (6797)
(11 hsp)
0.0 2055   49% PimS1 protein
Polyketide synthase
pimS1 Streptomyces natalensis
46
A0FCL1_STRVO
(A0FCL1)
Jump to Merid_00020
[query] 29 - 2629 (3073)
[subject] 2531 - 5051 (5721)
(11 hsp)
0.0 2050   52% MerA merA Streptomyces violaceoniger
47
F8QPG1_9ACTO
(F8QPG1)
[query] 1 - 2629 (3073)
[subject] 1 - 2681 (3621)
(5 hsp)
0.0 2048   49% Polyketide synthase natD Streptomyces sp. CS
48
D9XDI5_STRVR
(D9XDI5)
[query] 29 - 2635 (3073)
[subject] 34 - 2671 (2922)
(3 hsp)
0.0 2048   50% Type I polyketide synthase SSQG_00882 Streptomyces viridochromogenes DSM 40736
49
D9T6W4_MICAI
(D9T6W4)
[query] 5 - 2630 (3073)
[subject] 5071 - 7719 (9936)
(15 hsp)
0.0 2044   49% Beta-ketoacyl synthase Micau_2464 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
50
A1YAN0_AMYOR
(A1YAN0)
[query] 24 - 2636 (3073)
[subject] 1677 - 4189 (5099)
(6 hsp)
0.0 2043   50% Polyketide synthase type I Amycolatopsis orientalis
Nocardia orientalis
accessionDBtoolalignmentEvalueScoreIdent.linkinformationpubmed
1
Q8KUH4_ACTPA
(Q8KUH4)
[query] 1 - 3073 (3073)
[subject] 1 - 3073 (3073)
0.0 5775   100%
Product
Polyketide synthase
Gene
asmB
Organism
Actinosynnema pretiosum subsp. auranticum
1uniprot[Pubmed] 12060743 [Medline] 22056096
The biosynthetic gene cluster of the maytansinoid antitumor agent ansamitocin from Actinosynnema pretiosum.(Proc. Natl. Acad. Sci. U.S.A.) [2002]
2
C6W8L0_ACTMD
(C6W8L0)
[query] 564 - 3072 (3073)
[subject] 617 - 3147 (3148)
0.0 4180   94%
Product
Acyl transferase
Gene
Amir_3198
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
4
Q9ALM2_9PSEU
(Q9ALM2)
Jump to Spino_00210
[query] 1 - 2629 (3073)
[subject] 1 - 2666 (5588)
(7 hsp)
0.0 2133   49%
Product
Polyketide synthase extender modules 8-10
Gene
spnE
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 11358695 [Medline] 21257765
Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001]
6
C3VLW9_9ACTO
(C3VLW9)
[query] 2 - 2629 (3073)
[subject] 5 - 2521 (3377)
(4 hsp)
0.0 2129   50%
Product
Polyketide synthase type I
Gene
becF
Organism
Streptomyces sp. DSM 21069
1uniprot[Pubmed] 19875084
Biosynthesis of macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit.(Chem. Biol.) [2009]
7
Q30CR9_STRAU
(Q30CR9)
Jump to Alip_00160
[query] 2 - 2629 (3073)
[subject] 3 - 2632 (3277)
(5 hsp)
0.0 2126   49%
Product
LipPks4
Gene
lipPks4
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 16723573
Biosynthetic gene cluster for the polyenoyltetramic acid alpha-lipomycin.(Antimicrob. Agents Chemother.) [2006]
9
C3VLZ7_9ACTO
(C3VLZ7)
[query] 8 - 2629 (3073)
[subject] 21 - 2519 (3373)
(5 hsp)
0.0 2125   50%
Product
Polyketide synthase type I
Gene
mlaF
Organism
Streptomyces sp. MP39-85
1uniprot[Pubmed] 19854930
Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010]
10
C6WNW1_ACTMD
(C6WNW1)
[query] 29 - 2629 (3073)
[subject] 3599 - 6201 (7110)
(11 hsp)
0.0 2124   51%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Amir_2695
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
11
Q82QT4_STRAW
(Q82QT4)
[query] 23 - 2629 (3073)
[subject] 4280 - 6826 (7746)
(16 hsp)
0.0 2124   50%
Product
Modular polyketide synthase
Gene
pteA1
SAV419
SAV_419
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
12
F8QPG0_9ACTO
(F8QPG0)
[query] 29 - 2629 (3073)
[subject] 1776 - 4406 (5321)
(6 hsp)
0.0 2120   50%
Product
Polyketide synthase
Gene
natC
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
13
Q0R4M8_STRAT
(Q0R4M8)
Jump to Chth_00260
[query] 3 - 2629 (3073)
[subject] 1055 - 3765 (4699)
(8 hsp)
0.0 2119   50%
Product
ChlA1
Gene
 
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 16793515
Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006]
16
Q52V49_9ACTO
(Q52V49)
[query] 7 - 2629 (3073)
[subject] 9 - 2672 (3872)
(5 hsp)
0.0 2102   49%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
17
Q0S8W4_RHOSR
(Q0S8W4)
[query] 1 - 2632 (3073)
[subject] 1 - 2631 (3527)
(5 hsp)
0.0 2101   49%
Product
Type I polyketide synthase
Gene
RHA1_ro04231
Organism
Rhodococcus sp. (strain RHA1)
1uniprot[Pubmed] 17030794
The complete genome of Rhodococcus sp. RHA1 provides insights into a catabolic powerhouse.(Proc. Natl. Acad. Sci. U.S.A.) [2006]
20
C0SMW4_9ACTO
(C0SMW4)
Jump to Tauto_00110
[query] 18 - 2630 (3073)
[subject] 552 - 3154 (10827)
(18 hsp)
0.0 2096   50%
Product
Type I modular polyketide synthase
Gene
ttmJ
Organism
Streptomyces spiroverticillatus
1uniprot[Pubmed] 16707708
Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 18708355
Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008]
[pubmed all]
21
F1CT52_9ACTO
(F1CT52)
[query] 1 - 2629 (3073)
[subject] 1 - 2683 (3418)
(5 hsp)
0.0 2092   47%
Product
GdmAII
Gene
gdmAII
Organism
Streptomyces autolyticus
1uniprot[Pubmed] 21544574
Streptomyces autolyticus JX-47 Large-Insert Bacterial Artificial Chromosome Library Construction and Identification of Clones Covering Geldanamycin Biosynthesis Gene Cluster.(Curr. Microbiol.) [2011]
22
C9YYI2_STRSW
(C9YYI2)
[query] 29 - 2629 (3073)
[subject] 38 - 2682 (3919)
(5 hsp)
0.0 2087   50%
Product
Putative type I polyketide synthase
Gene
SCAB_83911
Organism
Streptomyces scabies (strain 87.22)
Streptomyces scabiei
1uniprot[Pubmed] 20064060
Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010]
23
Q6JHN6_9PSEU
(Q6JHN6)
[query] 29 - 2632 (3073)
[subject] 3768 - 6361 (7488)
(9 hsp)
0.0 2086   51%
Product
ObsC
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
24
F8QPF9_9ACTO
(F8QPF9)
[query] 29 - 2629 (3073)
[subject] 1786 - 4409 (5339)
(7 hsp)
0.0 2085   49%
Product
Polyketide synthase
Gene
natB
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
25
Q9ALM3_9PSEU
(Q9ALM3)
Jump to Spino_00200
[query] 1 - 2629 (3073)
[subject] 5 - 2669 (4928)
(9 hsp)
0.0 2084   49%
Product
Polyketide synthase extender modules 5-7
Gene
spnD
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 11358695 [Medline] 21257765
Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001]
27
D8HZ82_AMYMU
(D8HZ82)
[query] 29 - 2629 (3073)
[subject] 632 - 3054 (4735)
(11 hsp)
0.0 2082   51%
Product
Rifamycin polyketide synthase
Gene
rifA
AMED_0617
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
28
O54666_AMYMD
(O54666)
Jump to Rifam_00210
[query] 29 - 2629 (3073)
[subject] 632 - 3054 (4735)
(11 hsp)
0.0 2082   51%
Product
RifA
Rifamycin polyketide synthase, type 1
Gene
rifA
Organism
Amycolatopsis mediterranei
Nocardia mediterranei
1uniprot[Pubmed] 9512878 [Medline] 98174059
Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.(Chem. Biol.) [1998]
2uniprot[Pubmed] 9497318 [Medline] 98165773
3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.(J. Biol. Chem.) [1998]
3uniprot[Pubmed] 11278540 [Medline] 21201076
Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.(J. Biol. Chem.) [2001]
[pubmed all]
30
Q1WEK9_9ACTO
(Q1WEK9)
[query] 29 - 2629 (3073)
[subject] 2523 - 5049 (5712)
(11 hsp)
0.0 2079   51%
Product
Polyketide synthase
Gene
merA
Organism
Streptomyces sp. NRRL 30748
1uniprot[Pubmed] 16806745
Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006]
32
C3VLZ4_9ACTO
(C3VLZ4)
[query] 5 - 2637 (3073)
[subject] 6 - 2493 (3365)
(4 hsp)
0.0 2075   50%
Product
Polyketide synthase type I
Gene
mlaD
Organism
Streptomyces sp. MP39-85
1uniprot[Pubmed] 19854930
Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010]
34
F1CLC1_9ACTO
(F1CLC1)
[query] 29 - 2631 (3073)
[subject] 1578 - 4202 (6831)
(10 hsp)
0.0 2071   49%
Product
ScnS1
Gene
scnS1
Organism
Streptomyces chattanoogensis
1uniprot[Pubmed] 21330439
The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011]
35
Q6JHN7_9PSEU
(Q6JHN7)
[query] 29 - 2630 (3073)
[subject] 1723 - 4280 (5176)
(7 hsp)
0.0 2071   50%
Product
ObsB
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
38
O52545_AMYMD
(O52545)
Jump to Rifam_00220
[query] 4 - 2629 (3073)
[subject] 5 - 2573 (5060)
(8 hsp)
0.0 2062   49%
Product
RifB
Gene
rifB
Organism
Amycolatopsis mediterranei
Nocardia mediterranei
1uniprot[Pubmed] 9512878 [Medline] 98174059
Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.(Chem. Biol.) [1998]
2uniprot[Pubmed] 9497318 [Medline] 98165773
3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.(J. Biol. Chem.) [1998]
3uniprot[Pubmed] 11278540 [Medline] 21201076
Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.(J. Biol. Chem.) [2001]
[pubmed all]
39
D8HZ83_AMYMU
(D8HZ83)
[query] 4 - 2629 (3073)
[subject] 5 - 2573 (5060)
(8 hsp)
0.0 2061   49%
Product
Rifamycin polyketide synthase
Gene
rifB
AMED_0618
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
41
Q3S863_9ACTO
(Q3S863)
Jump to Conca_00070
[query] 16 - 2627 (3073)
[subject] 24 - 2671 (3982)
(6 hsp)
0.0 2060   49%
Product
Modular polyketide synthase
Gene
 
Organism
Streptomyces neyagawaensis
1uniprot[Pubmed] 16207901
Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005]
45
Q9X993_9ACTO
(Q9X993)
Jump to Pimar_00170
[query] 23 - 2631 (3073)
[subject] 1556 - 4170 (6797)
(11 hsp)
0.0 2055   49%
Product
PimS1 protein
Polyketide synthase
Gene
pimS1
Organism
Streptomyces natalensis
1uniprot[Pubmed] 10187796 [Medline] 99214571
The biosynthetic gene cluster for the 26-membered ring polyene macrolide pimaricin. A new polyketide synthase organization encoded by two subclusters separated by functionalization genes.(J. Biol. Chem.) [1999]
2uniprot[Pubmed] 11094342 [Medline] 20547809
A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000]
[pubmed all]
46
A0FCL1_STRVO
(A0FCL1)
Jump to Merid_00020
[query] 29 - 2629 (3073)
[subject] 2531 - 5051 (5721)
(11 hsp)
0.0 2050   52%
Product
MerA
Gene
merA
Organism
Streptomyces violaceoniger
1uniprot[Pubmed] 17159202
Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006]
47
F8QPG1_9ACTO
(F8QPG1)
[query] 1 - 2629 (3073)
[subject] 1 - 2681 (3621)
(5 hsp)
0.0 2048   49%
Product
Polyketide synthase
Gene
natD
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
50
A1YAN0_AMYOR
(A1YAN0)
[query] 24 - 2636 (3073)
[subject] 1677 - 4189 (5099)
(6 hsp)
0.0 2043   50%
Product
Polyketide synthase type I
Gene
 
Organism
Amycolatopsis orientalis
Nocardia orientalis
1uniprot[Pubmed] 17136886
Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006]