BLAST table : Aran_00070

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accessionDBtoolalignmentEvalueScoreIdent.linkproductgeneorganismec
1
A1C175_9ACTO
(A1C175)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
1e-146 523   100% Ketoreductase Streptomyces echinatus
2
D7BZR7_STRBB
(D7BZR7)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
1e-109 400   74% Short-chain dehydrogenase/reductase SDR SBI_06852 Streptomyces bingchenggensis (strain BCW-1)
3
Q6ZZV9_STRAT
(Q6ZZV9)
Jump to Ovied_00140
[query] 5 - 261 (261)
[subject] 4 - 260 (260)
1e-105 387   74% Ketoreductase ovmT Streptomyces antibioticus
4
C7QAF5_CATAD
(C7QAF5)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
1e-105 386   72% Short-chain dehydrogenase/reductase SDR Caci_3549 Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
5
A4X6Z5_SALTO
(A4X6Z5)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
1e-105 386   75% Short-chain dehydrogenase/reductase SDR Strop_2194 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
6
Q9AMJ0_STRAT
(Q9AMJ0)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
1e-105 384   72% Putative ketoreductase SimA6
Sim5
simA6
sim5
Streptomyces antibioticus
7
Q8VWB5_9ACTO
(Q8VWB5)
[query] 7 - 261 (261)
[subject] 7 - 261 (261)
1e-104 383   74% AknA aknA Streptomyces galilaeus
8
B5HT05_9ACTO
(B5HT05)
[query] 6 - 261 (261)
[subject] 7 - 262 (262)
1e-104 382   73% 3-oxoacyl-[acyl-carrier-protein] reductase SSEG_02722 Streptomyces sviceus ATCC 29083
9
Q54190_9ACTO
(Q54190)
[query] 7 - 261 (261)
[subject] 7 - 261 (261)
1e-104 380   74% Ketoacyl reductase aknIII Streptomyces galilaeus 1.3.1.-
10
Q9L553_9ACTO
(Q9L553)
Jump to Acla_00050
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
1e-103 380   72% AknA aknA Streptomyces galilaeus
11
Q54176_STRFR
(Q54176)
Jump to Urd_00150
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
1e-103 379   71% Putative ketoreductase UrdD Streptomyces fradiae
Streptomyces roseoflavus
12
Q84CJ4_9ACTO
(Q84CJ4)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
1e-102 377   72% Putative ketoreductase kinE Streptomyces murayamaensis
13
F2RC18_STRVP
(F2RC18)
[query] 4 - 261 (261)
[subject] 7 - 264 (264)
1e-102 376   72% Acetoacetyl-CoA reductase SVEN_5983 Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745) 1.1.1.36
14
D9W5A8_9ACTO
(D9W5A8)
[query] 6 - 261 (261)
[subject] 14 - 269 (269)
1e-102 376   74% 3-oxoacyl-[acyl-carrier-protein] reductase SSNG_07338 Streptomyces sp. C
15
Q84CH9_9ACTO
(Q84CH9)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
1e-102 376   71% Putative ketoreductase pd2E Streptomyces sp. WP 4669
16
Q93LY1_9ACTO
(Q93LY1)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
1e-102 375   71% Polyketide ketoreductase PgaD pgaD Streptomyces sp. PGA64
17
D9T2A7_MICAI
(D9T2A7)
[query] 8 - 261 (261)
[subject] 6 - 259 (259)
1e-102 375   74% Short-chain dehydrogenase/reductase SDR Micau_4010 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
18
B5G888_9ACTO
(B5G888)
[query] 7 - 261 (261)
[subject] 7 - 261 (261)
1e-102 375   74% Monensin polyketide synthase ketoacyl reductase SSBG_00496 Streptomyces sp. SPB74
19
E8W958_STRFA
(E8W958)
[query] 5 - 261 (261)
[subject] 11 - 267 (267)
1e-102 374   73% Short-chain dehydrogenase/reductase SDR Sfla_5324 Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD)
20
E8RWS2_MICSL
(E8RWS2)
[query] 8 - 261 (261)
[subject] 6 - 259 (259)
1e-102 374   74% Short-chain dehydrogenase/reductase SDR ML5_4411 Micromonospora sp. (strain L5)
21
D9UBK7_STRPR
(D9UBK7)
[query] 8 - 260 (261)
[subject] 11 - 263 (264)
1e-101 373   74% Putative ketoreductase c104_08c Streptomyces pristinaespiralis
22
B5HJY0_STRPR
(B5HJY0)
[query] 8 - 260 (261)
[subject] 11 - 263 (264)
1e-101 373   74% Ketoreductase SSDG_05477 Streptomyces pristinaespiralis ATCC 25486
23
DHKR_STRCM
(P41177)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
1e-101 373   73% Monensin polyketide synthase putative ketoacyl reductase
ORF5
Streptomyces cinnamonensis 1.3.1.-
24
Q935Z6_9ACTO
(Q935Z6)
[query] 7 - 261 (261)
[subject] 10 - 264 (264)
1e-101 373   72% RdmJ rdmJ Streptomyces purpurascens
25
C4NYK2_9ACTO
(C4NYK2)
[query] 8 - 261 (261)
[subject] 1 - 254 (254)
1e-101 371   70% SaqD saqD Micromonospora sp. Tu 6368
26
Q56166_9ACTO
(Q56166)
Jump to Jado_00110
[query] 4 - 261 (261)
[subject] 7 - 264 (264)
1e-100 368   70% Ketoreductase Streptomyces venezuelae
27
D2XDY2_9PSEU
(D2XDY2)
[query] 7 - 261 (261)
[subject] 3 - 257 (257)
1e-100 368   71% AzicD azicD Kibdelosporangium sp. MJ126-NF4
28
Q4R0M6_STRCX
(Q4R0M6)
Jump to Chart_00060
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
1e-99 367   73% ChaD protein chaD Streptomyces chartreusis
29
Q93LZ9_STRAU
(Q93LZ9)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
2e-99 366   70% Ketoreductase-like protein aur2E Streptomyces aureofaciens
30
Q56H99_STRAU
(Q56H99)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
3e-99 365   70% Aur1G aur1G Streptomyces aureofaciens
31
Q2HR23_9ACTO
(Q2HR23)
Jump to Sch475_00350
[query] 3 - 261 (261)
[subject] 8 - 266 (266)
3e-99 365   69% Putative ketoreducatse schP5 Streptomyces sp. SCC 2136
32
D1H093_9ACTO
(D1H093)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
3e-99 365   72% Putative polyketide ketoreductase chryF Streptomyces albaduncus
33
Q83X41_STRRO
(Q83X41)
[query] 4 - 261 (261)
[subject] 3 - 260 (260)
6e-99 364   72% Ketoreductase rocG Streptomyces rochei
Streptomyces parvullus
34
Q54220_STRGR
(Q54220)
Jump to Griseu_00040
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
1e-98 363   70% Ketoreductase Streptomyces griseus
35
D7RFJ8_AMYOR
(D7RFJ8)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
2e-98 362   70% Putative ketoreductase bexD Amycolatopsis orientalis subsp. vinearia
36
D1H0K9_9ACTO
(D1H0K9)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
9e-98 360   72% Putative ketoreductase ravF Streptomyces sp. C23201NS3
37
D5MRI8_9ACTO
(D5MRI8)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
2e-97 359   71% Putative ketoreductase hrbO Streptomyces sp. 2238-SVT4
38
D1XRF2_9ACTO
(D1XRF2)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
7e-97 357   69% Short-chain dehydrogenase/reductase SDR SACTEDRAFT_5262 Streptomyces sp. SA3_actE
39
D6MSV3_9ACTO
(D6MSV3)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
5e-96 355   69% SsfU ssfU Streptomyces sp. SF2575
40
Q47QL0_THEFY
(Q47QL0)
[query] 7 - 261 (261)
[subject] 6 - 261 (261)
7e-96 354   68% Ketoacyl reductase Tfu_1221 Thermobifida fusca (strain YX)
41
Q6VMJ0_STRAM
(Q6VMJ0)
[query] 6 - 261 (261)
[subject] 7 - 262 (262)
2e-95 353   68% Polyketide ketoreductase
Putative polyketide ketoreductase
alpD
DSMT0182
Streptomyces ambofaciens
42
Q1RQS3_STRAM
(Q1RQS3)
[query] 6 - 261 (261)
[subject] 7 - 262 (262)
2e-95 353   68% Polyketide ketoreductase alpD
SAMT0162
SAMT0163
Streptomyces ambofaciens ATCC 23877
43
F6K0W2_9BACT
(F6K0W2)
[query] 2 - 261 (261)
[subject] 1 - 260 (260)
2e-94 349   67% Ketoreductase uncultured bacterium BAC AB649/1850
44
D1A6T4_THECD
(D1A6T4)
[query] 5 - 261 (261)
[subject] 3 - 259 (259)
6e-94 348   70% Short-chain dehydrogenase/reductase SDR Tcur_2793 Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081)
45
Q67G28_9ACTO
(Q67G28)
Jump to Heda_00300
[query] 7 - 261 (261)
[subject] 5 - 259 (259)
2e-93 346   68% Keto reductase Streptomyces griseoruber
46
Q54812_STRPE
(Q54812)
Jump to Adria_00250
[query] 7 - 261 (261)
[subject] 7 - 261 (261)
2e-93 346   68% Daunorubicin-doxorubicin polyketide synthase dpsE Streptomyces peucetius
47
Q54491_STRNO
(Q54491)
Jump to Nogl_00330
[query] 1 - 261 (261)
[subject] 1 - 262 (262)
8e-92 341   69% SnoaD snoaD Streptomyces nogalater
48
Q9ZGD4_STRCY
(Q9ZGD4)
Jump to Lando_00060
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
2e-91 340   68% Reductase homolog lanD Streptomyces cyanogenus
49
Q3S8Q6_STRRM
(Q3S8Q6)
Jump to Oxtet_00100
[query] 7 - 261 (261)
[subject] 8 - 263 (263)
5e-91 338   69% OxyJ oxyJ Streptomyces rimosus
50
E3J3Q6_FRASU
(E3J3Q6)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
2e-90 336   63% Short-chain dehydrogenase/reductase SDR FraEuI1c_1326 Frankia sp. (strain EuI1c)
accessionDBtoolalignmentEvalueScoreIdent.linkinformationpubmed
2
D7BZR7_STRBB
(D7BZR7)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
1e-109 400   74%
Product
Short-chain dehydrogenase/reductase SDR
Gene
SBI_06852
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
4
C7QAF5_CATAD
(C7QAF5)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
1e-105 386   72%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Caci_3549
Organism
Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
1uniprot
Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).(Stand. Genomic Sci.) [2009]
6
Q9AMJ0_STRAT
(Q9AMJ0)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
1e-105 384   72%
Product
Putative ketoreductase SimA6
Sim5
Gene
simA6
sim5
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 11959542 [Medline] 21955989
Biosynthetic gene cluster of simocyclinone, a natural multihybrid antibiotic.(Antimicrob. Agents Chemother.) [2002]
2uniprot[Pubmed] 12115055 [Medline] 22109063
Cloning and analysis of the simocyclinone biosynthetic gene cluster of Streptomyces antibioticus Tu 6040.(Arch. Microbiol.) [2002]
[pubmed all]
7
Q8VWB5_9ACTO
(Q8VWB5)
[query] 7 - 261 (261)
[subject] 7 - 261 (261)
1e-104 383   74%
Product
AknA
Gene
aknA
Organism
Streptomyces galilaeus
1uniprot[Pubmed] 12399480 [Medline] 22286521
Expression, purification, and characterization of AknX anthrone oxygenase, which is involved in aklavinone biosynthesis in Streptomyces galilaeus.(J. Bacteriol.) [2002]
9
Q54190_9ACTO
(Q54190)
[query] 7 - 261 (261)
[subject] 7 - 261 (261)
1e-104 380   74%
Product
Ketoacyl reductase
Gene
aknIII
Organism
Streptomyces galilaeus
1uniprot[Pubmed] 8157619 [Medline] 94209255
Nucleotide sequence of the aknA region of the aklavinone biosynthetic gene cluster of Streptomyces galilaeus.(J. Bacteriol.) [1994]
10
Q9L553_9ACTO
(Q9L553)
Jump to Acla_00050
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
1e-103 380   72%
Product
AknA
Gene
aknA
Organism
Streptomyces galilaeus
1uniprot[Pubmed] 12137949 [Medline] 22133312
Cloning and characterization of Streptomyces galilaeus aclacinomycins polyketide synthase (PKS) cluster.(Gene) [2002]
11
Q54176_STRFR
(Q54176)
Jump to Urd_00150
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
1e-103 379   71%
Product
Putative ketoreductase
Gene
UrdD
Organism
Streptomyces fradiae
Streptomyces roseoflavus
1uniprot[Pubmed] 7592377 [Medline] 96042088
Cloning and characterization of a polyketide synthase from Streptomyces fradiae Tue2717 encoding the genes for biosynthesis of the angucycline antibiotic urdamycin A and a gene probably involved in its oxygenation.(J. Bacteriol.) [1995]
13
F2RC18_STRVP
(F2RC18)
[query] 4 - 261 (261)
[subject] 7 - 264 (264)
1e-102 376   72%
Product
Acetoacetyl-CoA reductase
Gene
SVEN_5983
Organism
Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
1uniprot[Pubmed] 21463507
Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011]
16
Q93LY1_9ACTO
(Q93LY1)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
1e-102 375   71%
Product
Polyketide ketoreductase PgaD
Gene
pgaD
Organism
Streptomyces sp. PGA64
1uniprot[Pubmed] 12654660 [Medline] 22540650
Engineering anthracycline biosynthesis toward angucyclines.(Antimicrob. Agents Chemother.) [2003]
2uniprot[Pubmed] 15515887
Partial activation of a silent angucycline-type gene cluster from a rubromycin beta producing Streptomyces sp. PGA64.(J. Antibiot.) [2004]
[pubmed all]
21
D9UBK7_STRPR
(D9UBK7)
[query] 8 - 260 (261)
[subject] 11 - 263 (264)
1e-101 373   74%
Product
Putative ketoreductase
Gene
c104_08c
Organism
Streptomyces pristinaespiralis
1uniprot[Pubmed] 21342465
Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis.(Microb Biotechnol) [2011]
23
DHKR_STRCM
(P41177)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
1e-101 373   73%
Product
Monensin polyketide synthase putative ketoacyl reductase
ORF5
Gene
 
Organism
Streptomyces cinnamonensis
1uniprot[Pubmed] 1508151 [Medline] 92374994
Characterisation of actI-homologous DNA encoding polyketide synthase genes from the monensin producer Streptomyces cinnamonensis.(Mol. Gen. Genet.) [1992]
25
C4NYK2_9ACTO
(C4NYK2)
[query] 8 - 261 (261)
[subject] 1 - 254 (254)
1e-101 371   70%
Product
SaqD
Gene
saqD
Organism
Micromonospora sp. Tu 6368
1uniprot[Pubmed] 17497146
A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007]
2uniprot[Pubmed] 19384899
Cloning and sequencing of the biosynthetic gene cluster for saquayamycin z and galtamycin B and the elucidation of the assembly of their saccharide chains.(Chembiochem) [2009]
[pubmed all]
26
Q56166_9ACTO
(Q56166)
Jump to Jado_00110
[query] 4 - 261 (261)
[subject] 7 - 264 (264)
1e-100 368   70%
Product
Ketoreductase
Gene
 
Organism
Streptomyces venezuelae
1uniprot[Pubmed] 7881555 [Medline] 95187308
Cloning and characterization of polyketide synthase genes for jadomycin B biosynthesis in Streptomyces venezuelae ISP5230.(Microbiology) [1994]
2uniprot
Functional characterization of the jadI gene as a cyclase forming angucyclinones.(J. Am. Chem. Soc.) [1999]
27
D2XDY2_9PSEU
(D2XDY2)
[query] 7 - 261 (261)
[subject] 3 - 257 (257)
1e-100 368   71%
Product
AzicD
Gene
azicD
Organism
Kibdelosporangium sp. MJ126-NF4
1uniprot[Pubmed] 19928906
Biosynthetic studies of aziridine formation in azicemicins.(J. Am. Chem. Soc.) [2009]
28
Q4R0M6_STRCX
(Q4R0M6)
Jump to Chart_00060
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
1e-99 367   73%
Product
ChaD protein
Gene
chaD
Organism
Streptomyces chartreusis
1uniprot[Pubmed] 15911378
Biosynthesis of the antitumor agent chartreusin involves the oxidative rearrangement of an anthracyclic polyketide.(Chem. Biol.) [2005]
29
Q93LZ9_STRAU
(Q93LZ9)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
2e-99 366   70%
Product
Ketoreductase-like protein
Gene
aur2E
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 15497441
Cloning and characterization of a new polyketide synthase gene cluster in Streptomyces aureofaciens CCM 3239.(DNA Seq.) [2004]
30
Q56H99_STRAU
(Q56H99)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
3e-99 365   70%
Product
Aur1G
Gene
aur1G
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 12384301 [Medline] 22271582
Cloning and characterization of a polyketide synthase gene cluster involved in biosynthesis of a proposed angucycline-like polyketide auricin in Streptomyces aureofaciens CCM 3239.(Gene) [2002]
2uniprot[Pubmed] 16079347
Characterization of a regulatory gene essential for the production of the angucycline-like polyketide antibiotic auricin in Streptomyces aureofaciens CCM 3239.(Microbiology) [2005]
3uniprot[Pubmed] 20466770
The role of the TetR-family transcriptional regulator Aur1R in negative regulation of the auricin gene cluster in Streptomyces aureofaciens CCM 3239.(Microbiology) [2010]
[pubmed all]
31
Q2HR23_9ACTO
(Q2HR23)
Jump to Sch475_00350
[query] 3 - 261 (261)
[subject] 8 - 266 (266)
3e-99 365   69%
Product
Putative ketoreducatse
Gene
schP5
Organism
Streptomyces sp. SCC 2136
1uniprot
Angucyclines Sch 47554 and Sch 47555 from Streptomyces sp. SCC-2136: Cloning, Sequencing, and Characterization.(Mol. Cells) [2006]
2uniprot
Molecular cloning and characterization of biosynthetic genes cluster of Sch 47554 from Streptomyces sp. SCC 2136. [2004]
33
Q83X41_STRRO
(Q83X41)
[query] 4 - 261 (261)
[subject] 3 - 260 (260)
6e-99 364   72%
Product
Ketoreductase
Gene
rocG
Organism
Streptomyces rochei
Streptomyces parvullus
1uniprot[Pubmed] 12791134 [Medline] 22676866
The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism.(Mol. Microbiol.) [2003]
2uniprot[Pubmed] 10954087 [Medline] 20408175
Cloning and analysis of the replication origin and the telomeres of the large linear plasmid pSLA2-L in Streptomyces rochei.(Mol. Gen. Genet.) [2000]
3uniprot[Pubmed] 10767533 [Medline] 20231737
Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei.(Gene) [2000]
4uniprot[Pubmed] 9836424 [Medline] 99053144
Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs.(Biosci. Biotechnol. Biochem.) [1998]
[pubmed all]
34
Q54220_STRGR
(Q54220)
Jump to Griseu_00040
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
1e-98 363   70%
Product
Ketoreductase
Gene
 
Organism
Streptomyces griseus
1uniprot[Pubmed] 8169211 [Medline] 94222841
Cloning, sequencing, and analysis of the griseusin polyketide synthase gene cluster from Streptomyces griseus.(J. Bacteriol.) [1994]
35
D7RFJ8_AMYOR
(D7RFJ8)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
2e-98 362   70%
Product
Putative ketoreductase
Gene
bexD
Organism
Amycolatopsis orientalis subsp. vinearia
1uniprot[Pubmed] 20443562
A biosynthetic pathway for BE-7585A, a 2-thiosugar-containing angucycline-type natural product.(J. Am. Chem. Soc.) [2010]
37
D5MRI8_9ACTO
(D5MRI8)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
2e-97 359   71%
Product
Putative ketoreductase
Gene
hrbO
Organism
Streptomyces sp. 2238-SVT4
1uniprot[Pubmed] 20453135
Cloning and characterization of a gene cluster for hatomarubigin biosynthesis in Streptomyces sp. strain 2238-SVT4.(Appl. Environ. Microbiol.) [2010]
39
D6MSV3_9ACTO
(D6MSV3)
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
5e-96 355   69%
Product
SsfU
Gene
ssfU
Organism
Streptomyces sp. SF2575
1uniprot[Pubmed] 19908837
Biochemical analysis of the biosynthetic pathway of an anticancer tetracycline SF2575.(J. Am. Chem. Soc.) [2009]
40
Q47QL0_THEFY
(Q47QL0)
[query] 7 - 261 (261)
[subject] 6 - 261 (261)
7e-96 354   68%
Product
Ketoacyl reductase
Gene
Tfu_1221
Organism
Thermobifida fusca (strain YX)
1uniprot[Pubmed] 17209016
Genome sequence and analysis of the soil cellulolytic actinomycete Thermobifida fusca YX.(J. Bacteriol.) [2007]
41
Q6VMJ0_STRAM
(Q6VMJ0)
[query] 6 - 261 (261)
[subject] 7 - 262 (262)
2e-95 353   68%
Product
Polyketide ketoreductase
Putative polyketide ketoreductase
Gene
alpD
DSMT0182
Organism
Streptomyces ambofaciens
1uniprot[Pubmed] 14742212
Functional angucycline-like antibiotic gene cluster in the terminal inverted repeats of the Streptomyces ambofaciens linear chromosome.(Antimicrob. Agents Chemother.) [2004]
2uniprot[Pubmed] 16952952
Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006]
[pubmed all]
42
Q1RQS3_STRAM
(Q1RQS3)
[query] 6 - 261 (261)
[subject] 7 - 262 (262)
2e-95 353   68%
Product
Polyketide ketoreductase
Gene
alpD
SAMT0162
SAMT0163
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16952952
Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
3uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
[pubmed all]
44
D1A6T4_THECD
(D1A6T4)
[query] 5 - 261 (261)
[subject] 3 - 259 (259)
6e-94 348   70%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Tcur_2793
Organism
Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081)
1uniprot
Complete genome sequence of Thermomonospora curvata type strain (B9).(Stand. Genomic Sci.) [2011]
45
Q67G28_9ACTO
(Q67G28)
Jump to Heda_00300
[query] 7 - 261 (261)
[subject] 5 - 259 (259)
2e-93 346   68%
Product
Keto reductase
Gene
 
Organism
Streptomyces griseoruber
1uniprot[Pubmed] 15271354
The hedamycin locus implicates a novel aromatic PKS priming mechanism.(Chem. Biol.) [2004]
46
Q54812_STRPE
(Q54812)
Jump to Adria_00250
[query] 7 - 261 (261)
[subject] 7 - 261 (261)
2e-93 346   68%
Product
Daunorubicin-doxorubicin polyketide synthase
Gene
dpsE
Organism
Streptomyces peucetius
1uniprot[Pubmed] 7828855 [Medline] 95129838
Characterization of the Streptomyces peucetius ATCC 29050 genes encoding doxorubicin polyketide synthase.(Gene) [1994]
47
Q54491_STRNO
(Q54491)
Jump to Nogl_00330
[query] 1 - 261 (261)
[subject] 1 - 262 (262)
8e-92 341   69%
Product
SnoaD
Gene
snoaD
Organism
Streptomyces nogalater
1uniprot[Pubmed] 8668120 [Medline] 96242142
A gene cluster involved in nogalamycin biosynthesis from Streptomyces nogalater: sequence analysis and complementation of early-block mutations in the anthracycline pathway.(Mol. Gen. Genet.) [1996]
2uniprot[Pubmed] 9349712 [Medline] 98007868
Characterization of Streptomyces nogalater genes encoding enzymes involved in glycosylation steps in nogalamycin biosynthesis.(Mol. Gen. Genet.) [1997]
3uniprot[Pubmed] 8760909 [Medline] 96349102
Production of hybrid anthracycline antibiotics by heterologous expression of Streptomyces nogalater nogalamycin biosynthesis genes.(Microbiology) [1996]
[pubmed all]
48
Q9ZGD4_STRCY
(Q9ZGD4)
Jump to Lando_00060
[query] 1 - 261 (261)
[subject] 1 - 261 (261)
2e-91 340   68%
Product
Reductase homolog
Gene
lanD
Organism
Streptomyces cyanogenus
1uniprot[Pubmed] 9933932 [Medline] 99132695
Cloning and characterization of a gene cluster from Streptomyces cyanogenus S136 probably involved in landomycin biosynthesis.(FEMS Microbiol. Lett.) [1999]
49
Q3S8Q6_STRRM
(Q3S8Q6)
Jump to Oxtet_00100
[query] 7 - 261 (261)
[subject] 8 - 263 (263)
5e-91 338   69%
Product
OxyJ
Gene
oxyJ
Organism
Streptomyces rimosus
1uniprot[Pubmed] 16597959
Engineered biosynthesis of a novel amidated polyketide, using the malonamyl-specific initiation module from the oxytetracycline polyketide synthase.(Appl. Environ. Microbiol.) [2006]