BLAST table : Aran_00090

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function
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accessionDBtoolalignmentEvalueScoreIdent.linkproductgeneorganismec
1
A1C177_9ACTO
(A1C177)
[query] 1 - 88 (88)
[subject] 1 - 88 (88)
7e-42 173   100% Acyl carrier protein Streptomyces echinatus
2
D7BZR1_STRBB
(D7BZR1)
[query] 1 - 88 (88)
[subject] 4 - 92 (94)
4e-23 111   65% Phosphopantetheine-binding protein SBI_06846 Streptomyces bingchenggensis (strain BCW-1)
3
D6MSY3_9ACTO
(D6MSY3)
[query] 1 - 83 (88)
[subject] 1 - 83 (85)
5e-19 97.8 54% SsfC ssfC Streptomyces sp. SF2575
4
D9UBS9_STRPR
(D9UBS9)
[query] 1 - 82 (88)
[subject] 1 - 82 (87)
4e-18 95.1 61% Putative acyl carrier protein cpp5 Streptomyces pristinaespiralis
5
Q0MRN3_9ACTO
(Q0MRN3)
[query] 1 - 83 (88)
[subject] 1 - 83 (87)
7e-18 94   59% Putative acyl carrier protein Streptomyces toxytricini
6
Q70J95_STRGR
(Q70J95)
Jump to Chro_00030
[query] 4 - 82 (88)
[subject] 2 - 80 (83)
1e-16 89.7 56% Acyl carrier protein cmmS Streptomyces griseus subsp. griseus
7
Q9X463_STRAE
(Q9X463)
Jump to Naphcy_00030
[query] 1 - 78 (88)
[subject] 1 - 78 (86)
2e-16 89.4 51% Acyl carrier protein ncnC Streptomyces arenae
8
Q53673_STRAA
(Q53673)
Jump to Mith_00160
[query] 4 - 88 (88)
[subject] 1 - 85 (85)
9e-16 87   52% Acyl carrier protein mtmS Streptomyces argillaceus
9
Q54219_STRGR
(Q54219)
Jump to Griseu_00030
[query] 3 - 78 (88)
[subject] 5 - 80 (89)
1e-15 87   55% Acyl carrier protein Streptomyces griseus
10
Q84CI0_9ACTO
(Q84CI0)
[query] 4 - 88 (88)
[subject] 6 - 90 (90)
2e-15 85.5 49% Putative acyl carrier protein pd2C Streptomyces sp. WP 4669
11
D2XDY1_9PSEU
(D2XDY1)
[query] 3 - 78 (88)
[subject] 4 - 79 (86)
3e-15 85.5 50% AzicC azicC Kibdelosporangium sp. MJ126-NF4
12
Q9FAR3_STRAU
(Q9FAR3)
[query] 1 - 82 (88)
[subject] 1 - 81 (84)
3e-15 85.1 55% Acyl carrier protein tcsF Streptomyces aureofaciens
13
Q9FCM6_STRAT
(Q9FCM6)
[query] 1 - 78 (88)
[subject] 1 - 78 (86)
4e-15 84.7 50% Putative Acyl carrier protein Streptomyces antibioticus
14
D1XRF1_9ACTO
(D1XRF1)
[query] 4 - 88 (88)
[subject] 7 - 91 (92)
6e-15 84.3 49% Phosphopantetheine-binding protein SACTEDRAFT_5261 Streptomyces sp. SA3_actE
15
F2RC17_STRVP
(F2RC17)
[query] 4 - 85 (88)
[subject] 6 - 87 (89)
8e-15 84   51% Acyl carrier protein SVEN_5982 Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
16
Q56165_9ACTO
(Q56165)
Jump to Jado_00100
[query] 4 - 85 (88)
[subject] 6 - 87 (89)
8e-15 84   51% Acyl carrier protein acp Streptomyces venezuelae
17
D9W8G0_9ACTO
(D9W8G0)
[query] 1 - 82 (88)
[subject] 1 - 82 (86)
9e-15 83.6 50% Granaticin polyketide synthase acyl carrier protein (ACP) SSOG_02380 Streptomyces himastatinicus ATCC 53653
18
Q2HR22_9ACTO
(Q2HR22)
Jump to Sch475_00360
[query] 3 - 78 (88)
[subject] 5 - 80 (89)
1e-14 83.2 53% Putative acyl carrier protein schP6 Streptomyces sp. SCC 2136
19
Q3S8R2_STRRM
(Q3S8R2)
Jump to Oxtet_00040
[query] 14 - 82 (88)
[subject] 14 - 82 (95)
1e-14 83.2 58% OxyC oxyC Streptomyces rimosus
20
ACPX_STRRM
(P43677)
[query] 14 - 82 (88)
[subject] 14 - 82 (95)
1e-14 83.2 58% Oxytetracycline polyketide synthase acyl carrier protein Streptomyces rimosus
21
D3U1U9_9BACT
(D3U1U9)
[query] 4 - 78 (88)
[subject] 7 - 81 (89)
2e-14 82.8 53% Acyl carrier protein uncultured soil bacterium V167
22
Q9F6C8_9ACTO
(Q9F6C8)
Jump to R1128_00140
[query] 4 - 74 (88)
[subject] 1 - 71 (82)
2e-14 82.4 54% Acyl carrier protein zhuN Streptomyces sp. R1128
23
Q9AMJ1_STRAT
(Q9AMJ1)
[query] 3 - 84 (88)
[subject] 5 - 86 (88)
3e-14 82   50% Putative acyl carrier protein SimA3
Sim4
simA3
sim4
Streptomyces antibioticus
24
B5G884_9ACTO
(B5G884)
[query] 1 - 88 (88)
[subject] 1 - 87 (92)
3e-14 81.6 48% Oxytetracycline polyketide synthase acyl carrier protein (ACP) SSBG_00492 Streptomyces sp. SPB74
25
E8W950_STRFA
(E8W950)
[query] 1 - 74 (88)
[subject] 1 - 74 (81)
4e-14 81.6 53% Phosphopantetheine-binding protein Sfla_5316 Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD)
26
E3T4B2_9ACTO
(E3T4B2)
[query] 1 - 78 (88)
[subject] 1 - 78 (85)
5e-14 81.3 51% Acyl carrier protein gra-orf3 Streptomyces vietnamensis
27
F4FBT5_VERMA
(F4FBT5)
[query] 1 - 81 (88)
[subject] 1 - 81 (85)
6e-14 80.9 49% Putative uncharacterized protein VAB18032_18165 Verrucosispora maris (strain AB-18-032)
28
Q9ZGD5_STRCY
(Q9ZGD5)
Jump to Lando_00050
[query] 3 - 81 (88)
[subject] 5 - 83 (89)
6e-14 80.9 52% Acyl carrier protein homolog lanC Streptomyces cyanogenus
29
Q2PA09_9ACTO
(Q2PA09)
Jump to Stref_00060
[query] 14 - 85 (88)
[subject] 14 - 86 (86)
6e-14 80.9 58% Acyl carrier protein stfS Streptomyces steffisburgensis
30
C7PWQ7_CATAD
(C7PWQ7)
[query] 3 - 78 (88)
[subject] 5 - 80 (102)
9e-14 80.1 51% Phosphopantetheine-binding Caci_6487 Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
31
Q56HA0_STRAU
(Q56HA0)
[query] 3 - 82 (88)
[subject] 10 - 89 (94)
1e-13 80.1 49% Aur1F aur1F Streptomyces aureofaciens
32
Q2J5E7_FRASC
(Q2J5E7)
[query] 4 - 74 (88)
[subject] 6 - 76 (98)
1e-13 80.1 52% Phosphopantetheine-binding Francci3_4147 Frankia sp. (strain CcI3)
33
Q8KSY8_9ACTO
(Q8KSY8)
Jump to Griseo_00040
[query] 1 - 82 (88)
[subject] 1 - 81 (86)
1e-13 80.1 54% Putative acyl carrier protein GrhC grhC Streptomyces sp. JP95
34
Q9XDZ8_9ACTO
(Q9XDZ8)
[query] 1 - 78 (88)
[subject] 1 - 78 (88)
2e-13 79.3 49% Polyketide synthase Actinomadura verrucosospora
35
Q93LY2_9ACTO
(Q93LY2)
[query] 3 - 84 (88)
[subject] 5 - 86 (89)
2e-13 79.3 49% Acyl carrier protein PgaC pgaC Streptomyces sp. PGA64
36
Q54283_SACHI
(Q54283)
[query] 1 - 78 (88)
[subject] 1 - 78 (85)
2e-13 79   49% Acyl carrier protein Saccharopolyspora hirsuta
37
C4NYK1_9ACTO
(C4NYK1)
[query] 3 - 82 (88)
[subject] 4 - 83 (90)
2e-13 79   51% SaqC saqC Micromonospora sp. Tu 6368
38
E5RLL9_9ACTO
(E5RLL9)
[query] 1 - 84 (88)
[subject] 1 - 84 (85)
2e-13 79   49% Putative acyl carrier protein pnxC Streptomyces sp. TA-0256
39
C0JWB6_9ACTO
(C0JWB6)
Jump to Polk_00210
[query] 1 - 74 (88)
[subject] 1 - 74 (85)
2e-13 79   54% PokP3 pokP3 Streptomyces diastatochromogenes
40
A8KQY0_9ACTO
(A8KQY0)
Jump to Ello_00130
[query] 4 - 82 (88)
[subject] 2 - 80 (83)
3e-13 78.6 46% Acyl carrier protein elmM Streptomyces olivaceus
41
Q84CJ5_9ACTO
(Q84CJ5)
[query] 4 - 82 (88)
[subject] 27 - 105 (110)
3e-13 78.6 51% Putative acyl carrier protein kinC Streptomyces murayamaensis
42
D2SZ01_MICEC
(D2SZ01)
[query] 4 - 82 (88)
[subject] 1 - 79 (82)
3e-13 78.6 46% Acyl carrier protein Micromonospora echinospora subsp. challisensis
43
Q54175_STRFR
(Q54175)
Jump to Urd_00140
[query] 3 - 78 (88)
[subject] 5 - 80 (89)
6e-13 77.8 49% Putative acyl carrier protein UrdC Streptomyces fradiae
Streptomyces roseoflavus
44
Q67G32_9ACTO
(Q67G32)
Jump to Heda_00260
[query] 1 - 83 (88)
[subject] 235 - 317 (319)
6e-13 77.8 46% Putative bifunctional cyclase dehydratase and ACP fusion Streptomyces griseoruber
45
D9UBR7_STRPR
(D9UBR7)
[query] 4 - 87 (88)
[subject] 1 - 80 (84)
6e-13 77.8 46% Putative acyl carrier protein cpp17 Streptomyces pristinaespiralis
46
B5HIU9_STRPR
(B5HIU9)
[query] 4 - 87 (88)
[subject] 1 - 80 (84)
6e-13 77.8 46% Acyl carrier protein SSDG_05086 Streptomyces pristinaespiralis ATCC 25486
47
D6EWA5_STRLI
(D6EWA5)
[query] 4 - 83 (88)
[subject] 5 - 84 (86)
7e-13 77.4 46% Acyl carrier protein SSPG_02600 Streptomyces lividans TK24
48
ACPX_STRCO
(Q02054)
Jump to Actino_00200
[query] 4 - 83 (88)
[subject] 5 - 84 (86)
7e-13 77.4 46% Actinorhodin polyketide synthase acyl carrier protein
actI ORF3
SCO5089
SCBAC28G1.15
Streptomyces coelicolor
49
Q4R0M0_STRCX
(Q4R0M0)
Jump to Chart_00120
[query] 1 - 83 (88)
[subject] 1 - 83 (85)
8e-13 77.4 46% ChaC protein chaC Streptomyces chartreusis
50
Q8VWB1_9ACTO
(Q8VWB1)
[query] 1 - 82 (88)
[subject] 1 - 81 (91)
8e-13 77.4 49% AknD aknD Streptomyces galilaeus
accessionDBtoolalignmentEvalueScoreIdent.linkinformationpubmed
2
D7BZR1_STRBB
(D7BZR1)
[query] 1 - 88 (88)
[subject] 4 - 92 (94)
4e-23 111   65%
Product
Phosphopantetheine-binding protein
Gene
SBI_06846
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
3
D6MSY3_9ACTO
(D6MSY3)
[query] 1 - 83 (88)
[subject] 1 - 83 (85)
5e-19 97.8 54%
Product
SsfC
Gene
ssfC
Organism
Streptomyces sp. SF2575
1uniprot[Pubmed] 19908837
Biochemical analysis of the biosynthetic pathway of an anticancer tetracycline SF2575.(J. Am. Chem. Soc.) [2009]
4
D9UBS9_STRPR
(D9UBS9)
[query] 1 - 82 (88)
[subject] 1 - 82 (87)
4e-18 95.1 61%
Product
Putative acyl carrier protein
Gene
cpp5
Organism
Streptomyces pristinaespiralis
1uniprot[Pubmed] 21342465
Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis.(Microb Biotechnol) [2011]
5
Q0MRN3_9ACTO
(Q0MRN3)
[query] 1 - 83 (88)
[subject] 1 - 83 (87)
7e-18 94   59%
Product
Putative acyl carrier protein
Gene
 
Organism
Streptomyces toxytricini
1uniprot[Pubmed] 17205043
Cloning and analysis of a type II polyketide synthase gene cluster from Streptomyces toxytricini NRRL 15,443.(J. Microbiol.) [2006]
7
Q9X463_STRAE
(Q9X463)
Jump to Naphcy_00030
[query] 1 - 78 (88)
[subject] 1 - 78 (86)
2e-16 89.4 51%
Product
Acyl carrier protein
Gene
ncnC
Organism
Streptomyces arenae
1uniprot[Pubmed] 10206788 [Medline] 99217421
Isolation and characterization of the naphthocyclinone gene cluster from Streptomyces arenae DSM 40737 and heterologous expression of the polyketide synthase genes.(Gene) [1999]
8
Q53673_STRAA
(Q53673)
Jump to Mith_00160
[query] 4 - 88 (88)
[subject] 1 - 85 (85)
9e-16 87   52%
Product
Acyl carrier protein
Gene
mtmS
Organism
Streptomyces argillaceus
1uniprot[Pubmed] 8654997 [Medline] 96257259
Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin.(Gene) [1996]
2uniprot[Pubmed] 8757400 [Medline] 96335144
An ABC transporter is essential for resistance to the antitumor agent mithramycin in the producer Streptomyces argillaceus.(Mol. Gen. Genet.) [1996]
3uniprot[Pubmed] 9150235 [Medline] 97294479
Cloning and insertional inactivation of Streptomyces argillaceus genes involved in the earliest steps of biosynthesis of the sugar moieties of the antitumor polyketide mithramycin.(J. Bacteriol.) [1997]
4uniprot[Pubmed] 9733697 [Medline] 98406047
Identification of two genes from Streptomyces argillaceus encoding glycosyltransferases involved in transfer of a disaccharide during biosynthesis of the antitumor drug mithramycin.(J. Bacteriol.) [1998]
5uniprot[Pubmed] 10102355 [Medline] 99200478
Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus.(Mol. Gen. Genet.) [1999]
6uniprot[Pubmed] 9889148 [Medline] 99111236
Oxidative cleavage of premithramycin B is one of the last steps in the biosynthesis of the antitumor drug mithramycin.(Chem. Biol.) [1999]
7uniprot[Pubmed] 10660060 [Medline] 20123456
Characterization of two glycosyltransferases involved in early glycosylation steps during biosynthesis of the antitumor polyketide mithramycin by Streptomyces argillaceus.(Mol. Gen. Genet.) [2000]
8uniprot[Pubmed] 11254130 [Medline] 21148776
The mtmVUC genes of the mithramycin gene cluster in Streptomyces argillaceus are involved in the biosynthesis of the sugar moieties.(Mol. Gen. Genet.) [2001]
9uniprot[Pubmed] 12733914 [Medline] 22619809
Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesis.(J. Am. Chem. Soc.) [2003]
10uniprot[Pubmed] 9917296 [Medline] 99115752
The structure of mithramycin reinvestigated.(J. Nat. Prod.) [1999]
11uniprot[Pubmed] 11853433 [Medline] 21843297
Ketopremithramycins and ketomithramycins, four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces argillaceus, reveal novel insights into post-PKS tailoring steps of the mithramycin biosynthetic pathway.(J. Am. Chem. Soc.) [2002]
12uniprot[Pubmed] 10652287 [Medline] 20119254
Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus.(J. Biol. Chem.) [2000]
13uniprot[Pubmed] 10779713 [Medline] 20243461
Insertional inactivation of mtrX and mtrY genes from the mithramycin gene cluster affects production and growth of the producer organism Streptomyces argillaceus.(FEMS Microbiol. Lett.) [2000]
14uniprot[Pubmed] 12022840 [Medline] 22017994
Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways.(J. Am. Chem. Soc.) [2002]
15uniprot[Pubmed] 12813091 [Medline] 22697398
Purification and characterization of a monooxygenase involved in the biosynthetic pathway of the antitumor drug mithramycin.(J. Bacteriol.) [2003]
16uniprot[Pubmed] 8807845 [Medline] 97113238
Deciphering the biosynthetic origin of the aglycone of the aureolic acid group of anti-tumor agents.(Chem. Biol.) [1996]
17uniprot[Pubmed] 14660589
MtmMII-mediated C-methylation during biosynthesis of the antitumor drug mithramycin is essential for biological activity and DNA-drug interaction.(J. Biol. Chem.) [2004]
18uniprot[Pubmed] 9375253 [Medline] 98042823
Folding of the polyketide chain is not dictated by minimal polyketide synthase in the biosynthesis of mithramycin and anthracycline.(Chem. Biol.) [1997]
19uniprot[Pubmed] 15712316
Elucidation of the glycosylation sequence of mithramycin biosynthesis: isolation of 3A-deolivosylpremithramycin B and its conversion to premithramycin B by glycosyltransferase MtmGII.(Chembiochem) [2005]
20uniprot[Pubmed] 10760873
The Novel Hybrid Antitumor Compound Premithramycinone H Provides Indirect Evidence for a Tricyclic Intermediate of the Biosynthesis of the Aureolic Acid Antibiotic Mithramycin.(Angew. Chem. Int. Ed.) [2000]
[pubmed all]
9
Q54219_STRGR
(Q54219)
Jump to Griseu_00030
[query] 3 - 78 (88)
[subject] 5 - 80 (89)
1e-15 87   55%
Product
Acyl carrier protein
Gene
 
Organism
Streptomyces griseus
1uniprot[Pubmed] 8169211 [Medline] 94222841
Cloning, sequencing, and analysis of the griseusin polyketide synthase gene cluster from Streptomyces griseus.(J. Bacteriol.) [1994]
11
D2XDY1_9PSEU
(D2XDY1)
[query] 3 - 78 (88)
[subject] 4 - 79 (86)
3e-15 85.5 50%
Product
AzicC
Gene
azicC
Organism
Kibdelosporangium sp. MJ126-NF4
1uniprot[Pubmed] 19928906
Biosynthetic studies of aziridine formation in azicemicins.(J. Am. Chem. Soc.) [2009]
13
Q9FCM6_STRAT
(Q9FCM6)
[query] 1 - 78 (88)
[subject] 1 - 78 (86)
4e-15 84.7 50%
Product
Putative Acyl carrier protein
Gene
 
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 11700358 [Medline] 21557167
A polyketide biosynthetic gene cluster from Streptomyces antibioticus includes a LysR-type transcriptional regulator.(Microbiology) [2001]
15
F2RC17_STRVP
(F2RC17)
[query] 4 - 85 (88)
[subject] 6 - 87 (89)
8e-15 84   51%
Product
Acyl carrier protein
Gene
SVEN_5982
Organism
Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
1uniprot[Pubmed] 21463507
Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011]
16
Q56165_9ACTO
(Q56165)
Jump to Jado_00100
[query] 4 - 85 (88)
[subject] 6 - 87 (89)
8e-15 84   51%
Product
Acyl carrier protein
Gene
acp
Organism
Streptomyces venezuelae
1uniprot[Pubmed] 7881555 [Medline] 95187308
Cloning and characterization of polyketide synthase genes for jadomycin B biosynthesis in Streptomyces venezuelae ISP5230.(Microbiology) [1994]
2uniprot
Functional characterization of the jadI gene as a cyclase forming angucyclinones.(J. Am. Chem. Soc.) [1999]
18
Q2HR22_9ACTO
(Q2HR22)
Jump to Sch475_00360
[query] 3 - 78 (88)
[subject] 5 - 80 (89)
1e-14 83.2 53%
Product
Putative acyl carrier protein
Gene
schP6
Organism
Streptomyces sp. SCC 2136
1uniprot
Angucyclines Sch 47554 and Sch 47555 from Streptomyces sp. SCC-2136: Cloning, Sequencing, and Characterization.(Mol. Cells) [2006]
2uniprot
Molecular cloning and characterization of biosynthetic genes cluster of Sch 47554 from Streptomyces sp. SCC 2136. [2004]
19
Q3S8R2_STRRM
(Q3S8R2)
Jump to Oxtet_00040
[query] 14 - 82 (88)
[subject] 14 - 82 (95)
1e-14 83.2 58%
Product
OxyC
Gene
oxyC
Organism
Streptomyces rimosus
1uniprot[Pubmed] 16597959
Engineered biosynthesis of a novel amidated polyketide, using the malonamyl-specific initiation module from the oxytetracycline polyketide synthase.(Appl. Environ. Microbiol.) [2006]
20
ACPX_STRRM
(P43677)
[query] 14 - 82 (88)
[subject] 14 - 82 (95)
1e-14 83.2 58%
Product
Oxytetracycline polyketide synthase acyl carrier protein
Gene
 
Organism
Streptomyces rimosus
1uniprot[Pubmed] 8163168 [Medline] 94215879
Sequences of the oxytetracycline polyketide synthase-encoding otc genes from Streptomyces rimosus.(Gene) [1994]
22
Q9F6C8_9ACTO
(Q9F6C8)
Jump to R1128_00140
[query] 4 - 74 (88)
[subject] 1 - 71 (82)
2e-14 82.4 54%
Product
Acyl carrier protein
Gene
zhuN
Organism
Streptomyces sp. R1128
1uniprot[Pubmed] 10931852 [Medline] 20517899
Cloning, nucleotide sequence, and heterologous expression of the biosynthetic gene cluster for R1128, a non-steroidal estrogen receptor antagonist. Insights into an unusual priming mechanism.(J. Biol. Chem.) [2000]
23
Q9AMJ1_STRAT
(Q9AMJ1)
[query] 3 - 84 (88)
[subject] 5 - 86 (88)
3e-14 82   50%
Product
Putative acyl carrier protein SimA3
Sim4
Gene
simA3
sim4
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 11959542 [Medline] 21955989
Biosynthetic gene cluster of simocyclinone, a natural multihybrid antibiotic.(Antimicrob. Agents Chemother.) [2002]
2uniprot[Pubmed] 12115055 [Medline] 22109063
Cloning and analysis of the simocyclinone biosynthetic gene cluster of Streptomyces antibioticus Tu 6040.(Arch. Microbiol.) [2002]
[pubmed all]
27
F4FBT5_VERMA
(F4FBT5)
[query] 1 - 81 (88)
[subject] 1 - 81 (85)
6e-14 80.9 49%
Product
Putative uncharacterized protein
Gene
VAB18032_18165
Organism
Verrucosispora maris (strain AB-18-032)
1uniprot[Pubmed] 21551311
Genome sequence of the abyssomicin- and proximicin-producing marine actinomycete Verrucosispora maris AB-18-032.(J. Bacteriol.) [2011]
28
Q9ZGD5_STRCY
(Q9ZGD5)
Jump to Lando_00050
[query] 3 - 81 (88)
[subject] 5 - 83 (89)
6e-14 80.9 52%
Product
Acyl carrier protein homolog
Gene
lanC
Organism
Streptomyces cyanogenus
1uniprot[Pubmed] 9933932 [Medline] 99132695
Cloning and characterization of a gene cluster from Streptomyces cyanogenus S136 probably involved in landomycin biosynthesis.(FEMS Microbiol. Lett.) [1999]
29
Q2PA09_9ACTO
(Q2PA09)
Jump to Stref_00060
[query] 14 - 85 (88)
[subject] 14 - 86 (86)
6e-14 80.9 58%
Product
Acyl carrier protein
Gene
stfS
Organism
Streptomyces steffisburgensis
1uniprot[Pubmed] 16751529
Isolation, characterization, and heterologous expression of the biosynthesis gene cluster for the antitumor anthracycline steffimycin.(Appl. Environ. Microbiol.) [2006]
30
C7PWQ7_CATAD
(C7PWQ7)
[query] 3 - 78 (88)
[subject] 5 - 80 (102)
9e-14 80.1 51%
Product
Phosphopantetheine-binding
Gene
Caci_6487
Organism
Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
1uniprot
Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).(Stand. Genomic Sci.) [2009]
31
Q56HA0_STRAU
(Q56HA0)
[query] 3 - 82 (88)
[subject] 10 - 89 (94)
1e-13 80.1 49%
Product
Aur1F
Gene
aur1F
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 12384301 [Medline] 22271582
Cloning and characterization of a polyketide synthase gene cluster involved in biosynthesis of a proposed angucycline-like polyketide auricin in Streptomyces aureofaciens CCM 3239.(Gene) [2002]
2uniprot[Pubmed] 16079347
Characterization of a regulatory gene essential for the production of the angucycline-like polyketide antibiotic auricin in Streptomyces aureofaciens CCM 3239.(Microbiology) [2005]
3uniprot[Pubmed] 20466770
The role of the TetR-family transcriptional regulator Aur1R in negative regulation of the auricin gene cluster in Streptomyces aureofaciens CCM 3239.(Microbiology) [2010]
[pubmed all]
32
Q2J5E7_FRASC
(Q2J5E7)
[query] 4 - 74 (88)
[subject] 6 - 76 (98)
1e-13 80.1 52%
Product
Phosphopantetheine-binding
Gene
Francci3_4147
Organism
Frankia sp. (strain CcI3)
1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]
33
Q8KSY8_9ACTO
(Q8KSY8)
Jump to Griseo_00040
[query] 1 - 82 (88)
[subject] 1 - 81 (86)
1e-13 80.1 54%
Product
Putative acyl carrier protein GrhC
Gene
grhC
Organism
Streptomyces sp. JP95
1uniprot[Pubmed] 12323376 [Medline] 22235582
A gene cluster from a marine Streptomyces encoding the biosynthesis of the aromatic spiroketal polyketide griseorhodin A.(Chem. Biol.) [2002]
34
Q9XDZ8_9ACTO
(Q9XDZ8)
[query] 1 - 78 (88)
[subject] 1 - 78 (88)
2e-13 79.3 49%
Product
Polyketide synthase
Gene
 
Organism
Actinomadura verrucosospora
1uniprot[Pubmed] 10347064 [Medline] 99278093
Development of a self-cloning system for Actinomadura verrucosospora and identification of polyketide synthase genes essential for production of the angucyclic antibiotic pradimicin.(Appl. Environ. Microbiol.) [1999]
35
Q93LY2_9ACTO
(Q93LY2)
[query] 3 - 84 (88)
[subject] 5 - 86 (89)
2e-13 79.3 49%
Product
Acyl carrier protein PgaC
Gene
pgaC
Organism
Streptomyces sp. PGA64
1uniprot[Pubmed] 12654660 [Medline] 22540650
Engineering anthracycline biosynthesis toward angucyclines.(Antimicrob. Agents Chemother.) [2003]
2uniprot[Pubmed] 15515887
Partial activation of a silent angucycline-type gene cluster from a rubromycin beta producing Streptomyces sp. PGA64.(J. Antibiot.) [2004]
[pubmed all]
36
Q54283_SACHI
(Q54283)
[query] 1 - 78 (88)
[subject] 1 - 78 (85)
2e-13 79   49%
Product
Acyl carrier protein
Gene
 
Organism
Saccharopolyspora hirsuta
1uniprot[Pubmed] 8341260 [Medline] 93341453
Saccharopolyspora hirsuta 367 encodes clustered genes similar to ketoacyl synthase, ketoacyl reductase, acyl carrier protein, and biotin carboxyl carrier protein.(Mol. Gen. Genet.) [1993]
37
C4NYK1_9ACTO
(C4NYK1)
[query] 3 - 82 (88)
[subject] 4 - 83 (90)
2e-13 79   51%
Product
SaqC
Gene
saqC
Organism
Micromonospora sp. Tu 6368
1uniprot[Pubmed] 17497146
A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007]
2uniprot[Pubmed] 19384899
Cloning and sequencing of the biosynthetic gene cluster for saquayamycin z and galtamycin B and the elucidation of the assembly of their saccharide chains.(Chembiochem) [2009]
[pubmed all]
39
C0JWB6_9ACTO
(C0JWB6)
Jump to Polk_00210
[query] 1 - 74 (88)
[subject] 1 - 74 (85)
2e-13 79   54%
Product
PokP3
Gene
pokP3
Organism
Streptomyces diastatochromogenes
1uniprot[Pubmed] 19266534
Organisation of the Biosynthetic Gene Cluster and Tailoring Enzymes in the Biosynthesis of the Tetracyclic Quinone Glycoside Antibiotic Polyketomycin.(Chembiochem) [2009]
40
A8KQY0_9ACTO
(A8KQY0)
Jump to Ello_00130
[query] 4 - 82 (88)
[subject] 2 - 80 (83)
3e-13 78.6 46%
Product
Acyl carrier protein
Gene
elmM
Organism
Streptomyces olivaceus
1uniprot[Pubmed] 18310024
Biosynthesis of elloramycin in Streptomyces olivaceus requires glycosylation by enzymes encoded outside the aglycon cluster.(Microbiology) [2008]
42
D2SZ01_MICEC
(D2SZ01)
[query] 4 - 82 (88)
[subject] 1 - 79 (82)
3e-13 78.6 46%
Product
Acyl carrier protein
Gene
 
Organism
Micromonospora echinospora subsp. challisensis
1uniprot[Pubmed] 19680283
TLN-05220, TLN-05223, new Echinosporamicin-type antibiotics, and proposed revision of the structure of bravomicins(*).(J. Antibiot.) [2009]
43
Q54175_STRFR
(Q54175)
Jump to Urd_00140
[query] 3 - 78 (88)
[subject] 5 - 80 (89)
6e-13 77.8 49%
Product
Putative acyl carrier protein
Gene
UrdC
Organism
Streptomyces fradiae
Streptomyces roseoflavus
1uniprot[Pubmed] 7592377 [Medline] 96042088
Cloning and characterization of a polyketide synthase from Streptomyces fradiae Tue2717 encoding the genes for biosynthesis of the angucycline antibiotic urdamycin A and a gene probably involved in its oxygenation.(J. Bacteriol.) [1995]
44
Q67G32_9ACTO
(Q67G32)
Jump to Heda_00260
[query] 1 - 83 (88)
[subject] 235 - 317 (319)
6e-13 77.8 46%
Product
Putative bifunctional cyclase dehydratase and ACP fusion
Gene
 
Organism
Streptomyces griseoruber
1uniprot[Pubmed] 15271354
The hedamycin locus implicates a novel aromatic PKS priming mechanism.(Chem. Biol.) [2004]
45
D9UBR7_STRPR
(D9UBR7)
[query] 4 - 87 (88)
[subject] 1 - 80 (84)
6e-13 77.8 46%
Product
Putative acyl carrier protein
Gene
cpp17
Organism
Streptomyces pristinaespiralis
1uniprot[Pubmed] 21342465
Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis.(Microb Biotechnol) [2011]
48
ACPX_STRCO
(Q02054)
Jump to Actino_00200
[query] 4 - 83 (88)
[subject] 5 - 84 (86)
7e-13 77.4 46%
Product
Actinorhodin polyketide synthase acyl carrier protein
actI ORF3
Gene
SCO5089
SCBAC28G1.15
Organism
Streptomyces coelicolor
1uniprot[Pubmed] 1527048 [Medline] 92406871
Nucleotide sequence and deduced functions of a set of cotranscribed genes of Streptomyces coelicolor A3(2) including the polyketide synthase for the antibiotic actinorhodin.(J. Biol. Chem.) [1992]
2uniprot[Pubmed] 12000953 [Medline] 21996410
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002]
3uniprot[Pubmed] 9166770 [Medline] 97309355
Solution structure of the actinorhodin polyketide synthase acyl carrier protein from Streptomyces coelicolor A3(2).(Biochemistry) [1997]
[pubmed all]
49
Q4R0M0_STRCX
(Q4R0M0)
Jump to Chart_00120
[query] 1 - 83 (88)
[subject] 1 - 83 (85)
8e-13 77.4 46%
Product
ChaC protein
Gene
chaC
Organism
Streptomyces chartreusis
1uniprot[Pubmed] 15911378
Biosynthesis of the antitumor agent chartreusin involves the oxidative rearrangement of an anthracyclic polyketide.(Chem. Biol.) [2005]
50
Q8VWB1_9ACTO
(Q8VWB1)
[query] 1 - 82 (88)
[subject] 1 - 81 (91)
8e-13 77.4 49%
Product
AknD
Gene
aknD
Organism
Streptomyces galilaeus
1uniprot[Pubmed] 12399480 [Medline] 22286521
Expression, purification, and characterization of AknX anthrone oxygenase, which is involved in aklavinone biosynthesis in Streptomyces galilaeus.(J. Bacteriol.) [2002]