BLAST table : Aran_00100

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function
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accessionDBtoolalignmentEvalueScoreIdent.linkproductgeneorganismec
1
A1C178_9ACTO
(A1C178)
[query] 1 - 408 (408)
[subject] 1 - 408 (408)
0.0 801   100% Chain length factor Streptomyces echinatus
2
Q93LZ7_STRAU
(Q93LZ7)
[query] 1 - 404 (408)
[subject] 14 - 418 (420)
1e-151 539   73% Chain length factor-like protein aur2B Streptomyces aureofaciens
3
D1XRF0_9ACTO
(D1XRF0)
[query] 1 - 404 (408)
[subject] 1 - 401 (404)
1e-149 532   68% Beta-ketoacyl synthase SACTEDRAFT_5260 Streptomyces sp. SA3_actE
4
Q6ZZW1_STRAT
(Q6ZZW1)
Jump to Ovied_00120
[query] 1 - 404 (408)
[subject] 1 - 405 (407)
1e-147 526   67% Keto-acyl synthase beta ovmK Streptomyces antibioticus
5
Q84CJ6_9ACTO
(Q84CJ6)
[query] 4 - 404 (408)
[subject] 2 - 402 (403)
1e-144 516   65% Putative chain length determinant kinB Streptomyces murayamaensis
6
D1H0J9_9ACTO
(D1H0J9)
[query] 10 - 404 (408)
[subject] 7 - 400 (401)
1e-144 516   66% Putative chain length factor ravB Streptomyces sp. C23201NS3
7
B5HT07_9ACTO
(B5HT07)
[query] 8 - 406 (408)
[subject] 5 - 403 (403)
1e-143 511   65% 3-oxoacyl-[acyl-carrier-protein] synthase 2 SSEG_09023 Streptomyces sviceus ATCC 29083
8
Q53672_STRAA
(Q53672)
Jump to Mith_00150
[query] 1 - 406 (408)
[subject] 1 - 408 (408)
1e-142 509   71% MtmK protein mtmK Streptomyces argillaceus
9
Q84CI1_9ACTO
(Q84CI1)
[query] 1 - 404 (408)
[subject] 1 - 405 (406)
1e-141 508   64% Putative chain length determinant pd2B Streptomyces sp. WP 4669
10
D2XDY0_9PSEU
(D2XDY0)
[query] 6 - 402 (408)
[subject] 4 - 399 (403)
1e-141 506   64% AzicB azicB Kibdelosporangium sp. MJ126-NF4
11
D9UBT0_STRPR
(D9UBT0)
[query] 4 - 403 (408)
[subject] 25 - 421 (427)
1e-141 505   70% Putative ketoacylsynthase, chain length factor beta-subunit cpp4 Streptomyces pristinaespiralis 2.3.1.179
12
Q4R0M1_STRCX
(Q4R0M1)
Jump to Chart_00110
[query] 4 - 404 (408)
[subject] 2 - 403 (408)
1e-141 504   67% ChaB protein chaB Streptomyces chartreusis
13
Q9AMJ2_STRAT
(Q9AMJ2)
[query] 4 - 402 (408)
[subject] 2 - 400 (404)
1e-140 504   67% Putative ketosynthase SimA2
Sim3
simA2
sim3
Streptomyces antibioticus
14
D7BZR0_STRBB
(D7BZR0)
[query] 4 - 403 (408)
[subject] 3 - 407 (412)
1e-140 503   74% Beta-ketoacyl synthase SBI_06845 Streptomyces bingchenggensis (strain BCW-1)
15
Q6VMI8_STRAM
(Q6VMI8)
[query] 4 - 405 (408)
[subject] 2 - 403 (403)
1e-139 499   68% Putative chain length determinant alpB
DSMT0184
Streptomyces ambofaciens
16
Q1RQS1_STRAM
(Q1RQS1)
[query] 4 - 405 (408)
[subject] 2 - 403 (403)
1e-139 499   68% Putative chain length determinant alpB
SAMT0164
SAMT0165
Streptomyces ambofaciens ATCC 23877
17
C4NYK0_9ACTO
(C4NYK0)
[query] 4 - 402 (408)
[subject] 2 - 401 (407)
1e-138 495   65% SaqB saqB Micromonospora sp. Tu 6368
18
Q56164_9ACTO
(Q56164)
Jump to Jado_00090
[query] 4 - 406 (408)
[subject] 2 - 404 (404)
1e-137 492   65% Chain length determinant Streptomyces venezuelae
19
Q54496_STRNO
(Q54496)
Jump to Nogl_00380
[query] 4 - 402 (408)
[subject] 2 - 401 (409)
1e-137 491   65% Snoa2 snoa2 Streptomyces nogalater
20
D6MSY2_9ACTO
(D6MSY2)
[query] 8 - 402 (408)
[subject] 12 - 408 (412)
1e-136 490   62% SsfB ssfB Streptomyces sp. SF2575
21
F2RC16_STRVP
(F2RC16)
[query] 4 - 406 (408)
[subject] 2 - 404 (404)
1e-136 488   65% Polyketide chain length factor SVEN_5981 Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
22
Q54174_STRFR
(Q54174)
Jump to Urd_00130
[query] 10 - 405 (408)
[subject] 11 - 407 (408)
1e-135 486   63% Putative chain length determinant UrdB Streptomyces fradiae
Streptomyces roseoflavus
23
D9W5B1_9ACTO
(D9W5B1)
[query] 8 - 402 (408)
[subject] 23 - 418 (421)
1e-135 485   69% 3-oxoacyl-[acyl-carrier-protein] synthase 2 SSNG_07341 Streptomyces sp. C
24
Q3S8R3_STRRM
(Q3S8R3)
Jump to Oxtet_00030
[query] 4 - 403 (408)
[subject] 19 - 419 (422)
1e-135 484   66% OxyB oxyB Streptomyces rimosus
25
Q9ZGD6_STRCY
(Q9ZGD6)
Jump to Lando_00040
[query] 4 - 402 (408)
[subject] 2 - 401 (406)
1e-133 480   62% Chain length factor homolog lanB Streptomyces cyanogenus
26
F6K0W4_9BACT
(F6K0W4)
[query] 8 - 402 (408)
[subject] 11 - 405 (420)
1e-132 477   65% Chain length determinant uncultured bacterium BAC AB649/1850
27
Q4U0Y7_9ACTO
(Q4U0Y7)
[query] 10 - 402 (408)
[subject] 11 - 404 (408)
1e-132 476   62% Type II PKS CLF domain Streptomyces nodosus
28
Q2HR21_9ACTO
(Q2HR21)
Jump to Sch475_00370
[query] 1 - 405 (408)
[subject] 1 - 406 (408)
1e-132 474   62% Putative chain length factor schP7 Streptomyces sp. SCC 2136
29
Q93LY3_9ACTO
(Q93LY3)
[query] 8 - 405 (408)
[subject] 6 - 404 (405)
1e-131 473   62% Chain length determinant PgaB pgaB Streptomyces sp. PGA64
30
Q56HA1_STRAU
(Q56HA1)
[query] 4 - 405 (408)
[subject] 2 - 403 (404)
1e-131 473   61% Aur1E aur1E Streptomyces aureofaciens
31
C7QAF3_CATAD
(C7QAF3)
[query] 8 - 407 (408)
[subject] 4 - 403 (403)
1e-130 471   66% Beta-ketoacyl synthase Caci_3547 Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
32
D1H0A2_9ACTO
(D1H0A2)
[query] 10 - 402 (408)
[subject] 7 - 398 (402)
1e-130 470   63% Putative chain length factor (KSa) chryB Streptomyces albaduncus
33
Q9FAR4_STRAU
(Q9FAR4)
[query] 8 - 404 (408)
[subject] 5 - 401 (401)
1e-129 464   64% Beta-ketoacyl synthase2 tcsE Streptomyces aureofaciens
34
D7RFJ6_AMYOR
(D7RFJ6)
[query] 8 - 405 (408)
[subject] 22 - 417 (423)
1e-127 459   65% Putative ketosynthase beta subunit bexB Amycolatopsis orientalis subsp. vinearia
35
Q47QL2_THEFY
(Q47QL2)
[query] 8 - 404 (408)
[subject] 5 - 401 (402)
1e-127 458   62% Actinorhodin polyketide beta-ketoacyl synthase beta subunit / 3-oxoacyl-ACP synthase II Tfu_1219 Thermobifida fusca (strain YX)
36
Q2PA08_9ACTO
(Q2PA08)
Jump to Stref_00070
[query] 8 - 403 (408)
[subject] 1 - 397 (406)
1e-127 458   65% Chain length factor stfK Streptomyces steffisburgensis
37
KASB_STRCO
(Q02062)
Jump to Actino_00190
[query] 6 - 402 (408)
[subject] 2 - 400 (407)
1e-126 457   61% Actinorhodin polyketide putative beta-ketoacyl synthase 2
actI ORF2
SCO5088
SCBAC28G1.14
Streptomyces coelicolor 2.3.1.-
38
D6EWA6_STRLI
(D6EWA6)
[query] 6 - 402 (408)
[subject] 2 - 400 (407)
1e-126 455   60% Beta-ketoacyl synthase/acyl transferase SSPG_02601 Streptomyces lividans TK24
39
D9W583_9ACTO
(D9W583)
[query] 8 - 405 (408)
[subject] 6 - 404 (405)
1e-125 453   61% 3-oxoacyl-[acyl-carrier-protein] synthase 2 SSNG_07313 Streptomyces sp. C
40
B6SEF2_9ACTO
(B6SEF2)
Jump to Alnu_00070
[query] 8 - 404 (408)
[subject] 21 - 424 (428)
1e-125 453   60% AlnM ketoacyl synthase beta alnM Streptomyces sp. CM020
41
Q70J89_STRGR
(Q70J89)
Jump to Chro_00090
[query] 7 - 404 (408)
[subject] 4 - 401 (422)
1e-125 452   62% Ketosynthase cmmK Streptomyces griseus subsp. griseus
42
Q9F6E1_9ACTO
(Q9F6E1)
Jump to R1128_00010
[query] 3 - 406 (408)
[subject] 7 - 412 (415)
1e-123 448   59% Chain length factor zhuA Streptomyces sp. R1128
43
Q9KHK5_9ACTO
(Q9KHK5)
Jump to Enter_00100
[query] 8 - 402 (408)
[subject] 6 - 403 (407)
1e-123 447   59% Putative keto synthase beta EncB encB Streptomyces maritimus
44
D1A6R4_THECD
(D1A6R4)
[query] 4 - 402 (408)
[subject] 2 - 401 (405)
1e-122 443   60% Beta-ketoacyl synthase Tcur_2772 Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081)
45
E3T4B1_9ACTO
(E3T4B1)
[query] 8 - 403 (408)
[subject] 17 - 415 (419)
1e-122 442   59% Polyketide synthase chain length factor gra-orf2 Streptomyces vietnamensis
46
E2EKK0_9ACTO
(E2EKK0)
[query] 6 - 402 (408)
[subject] 24 - 420 (423)
1e-121 441   58% Chain length factor sanG Streptomyces sp. SANK 61196
47
Q54282_SACHI
(Q54282)
[query] 10 - 406 (408)
[subject] 6 - 402 (403)
1e-121 441   60% Polyketide synthase Saccharopolyspora hirsuta
48
Q6S9W5_9ACTO
(Q6S9W5)
[query] 10 - 403 (408)
[subject] 7 - 400 (433)
1e-121 440   64% Chain length factor clf Streptomyces sp. 275
49
Q7WT09_9ACTO
(Q7WT09)
Jump to Medem_00330
[query] 8 - 404 (408)
[subject] 6 - 404 (408)
1e-120 438   58% Ketosynthase (KS) beta subunit med-ORF2 Streptomyces sp. AM-7161
50
Q9X462_STRAE
(Q9X462)
Jump to Naphcy_00020
[query] 17 - 403 (408)
[subject] 37 - 425 (429)
1e-120 437   62% Chain length factor ncnB Streptomyces arenae
accessionDBtoolalignmentEvalueScoreIdent.linkinformationpubmed
2
Q93LZ7_STRAU
(Q93LZ7)
[query] 1 - 404 (408)
[subject] 14 - 418 (420)
1e-151 539   73%
Product
Chain length factor-like protein
Gene
aur2B
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 15497441
Cloning and characterization of a new polyketide synthase gene cluster in Streptomyces aureofaciens CCM 3239.(DNA Seq.) [2004]
8
Q53672_STRAA
(Q53672)
Jump to Mith_00150
[query] 1 - 406 (408)
[subject] 1 - 408 (408)
1e-142 509   71%
Product
MtmK protein
Gene
mtmK
Organism
Streptomyces argillaceus
1uniprot[Pubmed] 8654997 [Medline] 96257259
Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin.(Gene) [1996]
2uniprot[Pubmed] 8757400 [Medline] 96335144
An ABC transporter is essential for resistance to the antitumor agent mithramycin in the producer Streptomyces argillaceus.(Mol. Gen. Genet.) [1996]
3uniprot[Pubmed] 9150235 [Medline] 97294479
Cloning and insertional inactivation of Streptomyces argillaceus genes involved in the earliest steps of biosynthesis of the sugar moieties of the antitumor polyketide mithramycin.(J. Bacteriol.) [1997]
4uniprot[Pubmed] 9733697 [Medline] 98406047
Identification of two genes from Streptomyces argillaceus encoding glycosyltransferases involved in transfer of a disaccharide during biosynthesis of the antitumor drug mithramycin.(J. Bacteriol.) [1998]
5uniprot[Pubmed] 10102355 [Medline] 99200478
Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus.(Mol. Gen. Genet.) [1999]
6uniprot[Pubmed] 9889148 [Medline] 99111236
Oxidative cleavage of premithramycin B is one of the last steps in the biosynthesis of the antitumor drug mithramycin.(Chem. Biol.) [1999]
7uniprot[Pubmed] 10660060 [Medline] 20123456
Characterization of two glycosyltransferases involved in early glycosylation steps during biosynthesis of the antitumor polyketide mithramycin by Streptomyces argillaceus.(Mol. Gen. Genet.) [2000]
8uniprot[Pubmed] 11254130 [Medline] 21148776
The mtmVUC genes of the mithramycin gene cluster in Streptomyces argillaceus are involved in the biosynthesis of the sugar moieties.(Mol. Gen. Genet.) [2001]
9uniprot[Pubmed] 12733914 [Medline] 22619809
Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesis.(J. Am. Chem. Soc.) [2003]
10uniprot[Pubmed] 9917296 [Medline] 99115752
The structure of mithramycin reinvestigated.(J. Nat. Prod.) [1999]
11uniprot[Pubmed] 11853433 [Medline] 21843297
Ketopremithramycins and ketomithramycins, four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces argillaceus, reveal novel insights into post-PKS tailoring steps of the mithramycin biosynthetic pathway.(J. Am. Chem. Soc.) [2002]
12uniprot[Pubmed] 10652287 [Medline] 20119254
Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus.(J. Biol. Chem.) [2000]
13uniprot[Pubmed] 10779713 [Medline] 20243461
Insertional inactivation of mtrX and mtrY genes from the mithramycin gene cluster affects production and growth of the producer organism Streptomyces argillaceus.(FEMS Microbiol. Lett.) [2000]
14uniprot[Pubmed] 12022840 [Medline] 22017994
Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways.(J. Am. Chem. Soc.) [2002]
15uniprot[Pubmed] 12813091 [Medline] 22697398
Purification and characterization of a monooxygenase involved in the biosynthetic pathway of the antitumor drug mithramycin.(J. Bacteriol.) [2003]
16uniprot[Pubmed] 8807845 [Medline] 97113238
Deciphering the biosynthetic origin of the aglycone of the aureolic acid group of anti-tumor agents.(Chem. Biol.) [1996]
17uniprot[Pubmed] 14660589
MtmMII-mediated C-methylation during biosynthesis of the antitumor drug mithramycin is essential for biological activity and DNA-drug interaction.(J. Biol. Chem.) [2004]
18uniprot[Pubmed] 9375253 [Medline] 98042823
Folding of the polyketide chain is not dictated by minimal polyketide synthase in the biosynthesis of mithramycin and anthracycline.(Chem. Biol.) [1997]
19uniprot[Pubmed] 15712316
Elucidation of the glycosylation sequence of mithramycin biosynthesis: isolation of 3A-deolivosylpremithramycin B and its conversion to premithramycin B by glycosyltransferase MtmGII.(Chembiochem) [2005]
20uniprot[Pubmed] 10760873
The Novel Hybrid Antitumor Compound Premithramycinone H Provides Indirect Evidence for a Tricyclic Intermediate of the Biosynthesis of the Aureolic Acid Antibiotic Mithramycin.(Angew. Chem. Int. Ed.) [2000]
[pubmed all]
10
D2XDY0_9PSEU
(D2XDY0)
[query] 6 - 402 (408)
[subject] 4 - 399 (403)
1e-141 506   64%
Product
AzicB
Gene
azicB
Organism
Kibdelosporangium sp. MJ126-NF4
1uniprot[Pubmed] 19928906
Biosynthetic studies of aziridine formation in azicemicins.(J. Am. Chem. Soc.) [2009]
11
D9UBT0_STRPR
(D9UBT0)
[query] 4 - 403 (408)
[subject] 25 - 421 (427)
1e-141 505   70%
Product
Putative ketoacylsynthase, chain length factor beta-subunit
Gene
cpp4
Organism
Streptomyces pristinaespiralis
1uniprot[Pubmed] 21342465
Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis.(Microb Biotechnol) [2011]
12
Q4R0M1_STRCX
(Q4R0M1)
Jump to Chart_00110
[query] 4 - 404 (408)
[subject] 2 - 403 (408)
1e-141 504   67%
Product
ChaB protein
Gene
chaB
Organism
Streptomyces chartreusis
1uniprot[Pubmed] 15911378
Biosynthesis of the antitumor agent chartreusin involves the oxidative rearrangement of an anthracyclic polyketide.(Chem. Biol.) [2005]
13
Q9AMJ2_STRAT
(Q9AMJ2)
[query] 4 - 402 (408)
[subject] 2 - 400 (404)
1e-140 504   67%
Product
Putative ketosynthase SimA2
Sim3
Gene
simA2
sim3
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 11959542 [Medline] 21955989
Biosynthetic gene cluster of simocyclinone, a natural multihybrid antibiotic.(Antimicrob. Agents Chemother.) [2002]
2uniprot[Pubmed] 12115055 [Medline] 22109063
Cloning and analysis of the simocyclinone biosynthetic gene cluster of Streptomyces antibioticus Tu 6040.(Arch. Microbiol.) [2002]
[pubmed all]
14
D7BZR0_STRBB
(D7BZR0)
[query] 4 - 403 (408)
[subject] 3 - 407 (412)
1e-140 503   74%
Product
Beta-ketoacyl synthase
Gene
SBI_06845
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
15
Q6VMI8_STRAM
(Q6VMI8)
[query] 4 - 405 (408)
[subject] 2 - 403 (403)
1e-139 499   68%
Product
Putative chain length determinant
Gene
alpB
DSMT0184
Organism
Streptomyces ambofaciens
1uniprot[Pubmed] 14742212
Functional angucycline-like antibiotic gene cluster in the terminal inverted repeats of the Streptomyces ambofaciens linear chromosome.(Antimicrob. Agents Chemother.) [2004]
2uniprot[Pubmed] 16952952
Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006]
[pubmed all]
16
Q1RQS1_STRAM
(Q1RQS1)
[query] 4 - 405 (408)
[subject] 2 - 403 (403)
1e-139 499   68%
Product
Putative chain length determinant
Gene
alpB
SAMT0164
SAMT0165
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16952952
Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
3uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
[pubmed all]
17
C4NYK0_9ACTO
(C4NYK0)
[query] 4 - 402 (408)
[subject] 2 - 401 (407)
1e-138 495   65%
Product
SaqB
Gene
saqB
Organism
Micromonospora sp. Tu 6368
1uniprot[Pubmed] 17497146
A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007]
2uniprot[Pubmed] 19384899
Cloning and sequencing of the biosynthetic gene cluster for saquayamycin z and galtamycin B and the elucidation of the assembly of their saccharide chains.(Chembiochem) [2009]
[pubmed all]
18
Q56164_9ACTO
(Q56164)
Jump to Jado_00090
[query] 4 - 406 (408)
[subject] 2 - 404 (404)
1e-137 492   65%
Product
Chain length determinant
Gene
 
Organism
Streptomyces venezuelae
1uniprot[Pubmed] 7881555 [Medline] 95187308
Cloning and characterization of polyketide synthase genes for jadomycin B biosynthesis in Streptomyces venezuelae ISP5230.(Microbiology) [1994]
2uniprot
Functional characterization of the jadI gene as a cyclase forming angucyclinones.(J. Am. Chem. Soc.) [1999]
19
Q54496_STRNO
(Q54496)
Jump to Nogl_00380
[query] 4 - 402 (408)
[subject] 2 - 401 (409)
1e-137 491   65%
Product
Snoa2
Gene
snoa2
Organism
Streptomyces nogalater
1uniprot[Pubmed] 8668120 [Medline] 96242142
A gene cluster involved in nogalamycin biosynthesis from Streptomyces nogalater: sequence analysis and complementation of early-block mutations in the anthracycline pathway.(Mol. Gen. Genet.) [1996]
2uniprot[Pubmed] 9349712 [Medline] 98007868
Characterization of Streptomyces nogalater genes encoding enzymes involved in glycosylation steps in nogalamycin biosynthesis.(Mol. Gen. Genet.) [1997]
3uniprot[Pubmed] 8760909 [Medline] 96349102
Production of hybrid anthracycline antibiotics by heterologous expression of Streptomyces nogalater nogalamycin biosynthesis genes.(Microbiology) [1996]
[pubmed all]
20
D6MSY2_9ACTO
(D6MSY2)
[query] 8 - 402 (408)
[subject] 12 - 408 (412)
1e-136 490   62%
Product
SsfB
Gene
ssfB
Organism
Streptomyces sp. SF2575
1uniprot[Pubmed] 19908837
Biochemical analysis of the biosynthetic pathway of an anticancer tetracycline SF2575.(J. Am. Chem. Soc.) [2009]
21
F2RC16_STRVP
(F2RC16)
[query] 4 - 406 (408)
[subject] 2 - 404 (404)
1e-136 488   65%
Product
Polyketide chain length factor
Gene
SVEN_5981
Organism
Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
1uniprot[Pubmed] 21463507
Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011]
22
Q54174_STRFR
(Q54174)
Jump to Urd_00130
[query] 10 - 405 (408)
[subject] 11 - 407 (408)
1e-135 486   63%
Product
Putative chain length determinant
Gene
UrdB
Organism
Streptomyces fradiae
Streptomyces roseoflavus
1uniprot[Pubmed] 7592377 [Medline] 96042088
Cloning and characterization of a polyketide synthase from Streptomyces fradiae Tue2717 encoding the genes for biosynthesis of the angucycline antibiotic urdamycin A and a gene probably involved in its oxygenation.(J. Bacteriol.) [1995]
24
Q3S8R3_STRRM
(Q3S8R3)
Jump to Oxtet_00030
[query] 4 - 403 (408)
[subject] 19 - 419 (422)
1e-135 484   66%
Product
OxyB
Gene
oxyB
Organism
Streptomyces rimosus
1uniprot[Pubmed] 16597959
Engineered biosynthesis of a novel amidated polyketide, using the malonamyl-specific initiation module from the oxytetracycline polyketide synthase.(Appl. Environ. Microbiol.) [2006]
25
Q9ZGD6_STRCY
(Q9ZGD6)
Jump to Lando_00040
[query] 4 - 402 (408)
[subject] 2 - 401 (406)
1e-133 480   62%
Product
Chain length factor homolog
Gene
lanB
Organism
Streptomyces cyanogenus
1uniprot[Pubmed] 9933932 [Medline] 99132695
Cloning and characterization of a gene cluster from Streptomyces cyanogenus S136 probably involved in landomycin biosynthesis.(FEMS Microbiol. Lett.) [1999]
27
Q4U0Y7_9ACTO
(Q4U0Y7)
[query] 10 - 402 (408)
[subject] 11 - 404 (408)
1e-132 476   62%
Product
Type II PKS CLF domain
Gene
 
Organism
Streptomyces nodosus
1uniprot[Pubmed] 16832727
Amplification of DNA encoding entire type I polyketide synthase domains and linkers from streptomyces species.(Curr. Microbiol.) [2006]
28
Q2HR21_9ACTO
(Q2HR21)
Jump to Sch475_00370
[query] 1 - 405 (408)
[subject] 1 - 406 (408)
1e-132 474   62%
Product
Putative chain length factor
Gene
schP7
Organism
Streptomyces sp. SCC 2136
1uniprot
Angucyclines Sch 47554 and Sch 47555 from Streptomyces sp. SCC-2136: Cloning, Sequencing, and Characterization.(Mol. Cells) [2006]
2uniprot
Molecular cloning and characterization of biosynthetic genes cluster of Sch 47554 from Streptomyces sp. SCC 2136. [2004]
29
Q93LY3_9ACTO
(Q93LY3)
[query] 8 - 405 (408)
[subject] 6 - 404 (405)
1e-131 473   62%
Product
Chain length determinant PgaB
Gene
pgaB
Organism
Streptomyces sp. PGA64
1uniprot[Pubmed] 12654660 [Medline] 22540650
Engineering anthracycline biosynthesis toward angucyclines.(Antimicrob. Agents Chemother.) [2003]
2uniprot[Pubmed] 15515887
Partial activation of a silent angucycline-type gene cluster from a rubromycin beta producing Streptomyces sp. PGA64.(J. Antibiot.) [2004]
[pubmed all]
30
Q56HA1_STRAU
(Q56HA1)
[query] 4 - 405 (408)
[subject] 2 - 403 (404)
1e-131 473   61%
Product
Aur1E
Gene
aur1E
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 12384301 [Medline] 22271582
Cloning and characterization of a polyketide synthase gene cluster involved in biosynthesis of a proposed angucycline-like polyketide auricin in Streptomyces aureofaciens CCM 3239.(Gene) [2002]
2uniprot[Pubmed] 16079347
Characterization of a regulatory gene essential for the production of the angucycline-like polyketide antibiotic auricin in Streptomyces aureofaciens CCM 3239.(Microbiology) [2005]
3uniprot[Pubmed] 20466770
The role of the TetR-family transcriptional regulator Aur1R in negative regulation of the auricin gene cluster in Streptomyces aureofaciens CCM 3239.(Microbiology) [2010]
[pubmed all]
31
C7QAF3_CATAD
(C7QAF3)
[query] 8 - 407 (408)
[subject] 4 - 403 (403)
1e-130 471   66%
Product
Beta-ketoacyl synthase
Gene
Caci_3547
Organism
Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
1uniprot
Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).(Stand. Genomic Sci.) [2009]
34
D7RFJ6_AMYOR
(D7RFJ6)
[query] 8 - 405 (408)
[subject] 22 - 417 (423)
1e-127 459   65%
Product
Putative ketosynthase beta subunit
Gene
bexB
Organism
Amycolatopsis orientalis subsp. vinearia
1uniprot[Pubmed] 20443562
A biosynthetic pathway for BE-7585A, a 2-thiosugar-containing angucycline-type natural product.(J. Am. Chem. Soc.) [2010]
35
Q47QL2_THEFY
(Q47QL2)
[query] 8 - 404 (408)
[subject] 5 - 401 (402)
1e-127 458   62%
Product
Actinorhodin polyketide beta-ketoacyl synthase beta subunit / 3-oxoacyl-ACP synthase II
Gene
Tfu_1219
Organism
Thermobifida fusca (strain YX)
1uniprot[Pubmed] 17209016
Genome sequence and analysis of the soil cellulolytic actinomycete Thermobifida fusca YX.(J. Bacteriol.) [2007]
36
Q2PA08_9ACTO
(Q2PA08)
Jump to Stref_00070
[query] 8 - 403 (408)
[subject] 1 - 397 (406)
1e-127 458   65%
Product
Chain length factor
Gene
stfK
Organism
Streptomyces steffisburgensis
1uniprot[Pubmed] 16751529
Isolation, characterization, and heterologous expression of the biosynthesis gene cluster for the antitumor anthracycline steffimycin.(Appl. Environ. Microbiol.) [2006]
37
KASB_STRCO
(Q02062)
Jump to Actino_00190
[query] 6 - 402 (408)
[subject] 2 - 400 (407)
1e-126 457   61%
Product
Actinorhodin polyketide putative beta-ketoacyl synthase 2
actI ORF2
Gene
SCO5088
SCBAC28G1.14
Organism
Streptomyces coelicolor
1uniprot[Pubmed] 1527048 [Medline] 92406871
Nucleotide sequence and deduced functions of a set of cotranscribed genes of Streptomyces coelicolor A3(2) including the polyketide synthase for the antibiotic actinorhodin.(J. Biol. Chem.) [1992]
2uniprot[Pubmed] 12000953 [Medline] 21996410
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002]
[pubmed all]
40
B6SEF2_9ACTO
(B6SEF2)
Jump to Alnu_00070
[query] 8 - 404 (408)
[subject] 21 - 424 (428)
1e-125 453   60%
Product
AlnM ketoacyl synthase beta
Gene
alnM
Organism
Streptomyces sp. CM020
1uniprot[Pubmed] 18940666
Characterization of the alnumycin gene cluster reveals unusual gene products for pyran ring formation and dioxan biosynthesis.(Chem. Biol.) [2008]
42
Q9F6E1_9ACTO
(Q9F6E1)
Jump to R1128_00010
[query] 3 - 406 (408)
[subject] 7 - 412 (415)
1e-123 448   59%
Product
Chain length factor
Gene
zhuA
Organism
Streptomyces sp. R1128
1uniprot[Pubmed] 10931852 [Medline] 20517899
Cloning, nucleotide sequence, and heterologous expression of the biosynthetic gene cluster for R1128, a non-steroidal estrogen receptor antagonist. Insights into an unusual priming mechanism.(J. Biol. Chem.) [2000]
43
Q9KHK5_9ACTO
(Q9KHK5)
Jump to Enter_00100
[query] 8 - 402 (408)
[subject] 6 - 403 (407)
1e-123 447   59%
Product
Putative keto synthase beta EncB
Gene
encB
Organism
Streptomyces maritimus
1uniprot
Natural Metabolic Diversity Encoded by the Enterocin Biosynthesis Gene Cluster.(J. Am. Chem. Soc.) [2000]
2uniprot[Pubmed] 11137817 [Medline] 20579517
Cloning, sequencing and analysis of the enterocin biosynthesis gene cluster from the marine isolate 'Streptomyces maritimus': evidence for the derailment of an aromatic polyketide synthase.(Chem. Biol.) [2000]
3uniprot[Pubmed] 11948863 [Medline] 21942282
A mechanism of benzoic acid biosynthesis in plants and bacteria that mirrors fatty acid beta-oxidation.(Chembiochem) [2001]
[pubmed all]
44
D1A6R4_THECD
(D1A6R4)
[query] 4 - 402 (408)
[subject] 2 - 401 (405)
1e-122 443   60%
Product
Beta-ketoacyl synthase
Gene
Tcur_2772
Organism
Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081)
1uniprot
Complete genome sequence of Thermomonospora curvata type strain (B9).(Stand. Genomic Sci.) [2011]
46
E2EKK0_9ACTO
(E2EKK0)
[query] 6 - 402 (408)
[subject] 24 - 420 (423)
1e-121 441   58%
Product
Chain length factor
Gene
sanG
Organism
Streptomyces sp. SANK 61196
1uniprot[Pubmed] 20550125
Cloning, sequencing, heterologous expression, and mechanistic analysis of A-74528 biosynthesis.(J. Am. Chem. Soc.) [2010]
47
Q54282_SACHI
(Q54282)
[query] 10 - 406 (408)
[subject] 6 - 402 (403)
1e-121 441   60%
Product
Polyketide synthase
Gene
 
Organism
Saccharopolyspora hirsuta
1uniprot[Pubmed] 8341260 [Medline] 93341453
Saccharopolyspora hirsuta 367 encodes clustered genes similar to ketoacyl synthase, ketoacyl reductase, acyl carrier protein, and biotin carboxyl carrier protein.(Mol. Gen. Genet.) [1993]
49
Q7WT09_9ACTO
(Q7WT09)
Jump to Medem_00330
[query] 8 - 404 (408)
[subject] 6 - 404 (408)
1e-120 438   58%
Product
Ketosynthase (KS) beta subunit
Gene
med-ORF2
Organism
Streptomyces sp. AM-7161
1uniprot
Cloning, sequencing and heterologous expression of the medermycin biosynthetic gene cluster of Streptomyces sp. AM-7161: towards comparative analysis of the benzoisochromanequione gene clusters.(Microbiology (Mosc.)) [2003]
50
Q9X462_STRAE
(Q9X462)
Jump to Naphcy_00020
[query] 17 - 403 (408)
[subject] 37 - 425 (429)
1e-120 437   62%
Product
Chain length factor
Gene
ncnB
Organism
Streptomyces arenae
1uniprot[Pubmed] 10206788 [Medline] 99217421
Isolation and characterization of the naphthocyclinone gene cluster from Streptomyces arenae DSM 40737 and heterologous expression of the polyketide synthase genes.(Gene) [1999]