BLAST table : Aran_00160

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function
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accessionDBtoolalignmentEvalueScoreIdent.linkproductgeneorganismec
1
D9UBN4_STRPR
(D9UBN4)
[query] 38 - 131 (139)
[subject] 1 - 94 (97)
7e-24 114   59% Putative oxygenase c101_13 Streptomyces pristinaespiralis
2
D6X7X8_STRPR
(D6X7X8)
[query] 38 - 131 (139)
[subject] 1 - 94 (97)
7e-24 114   59% Predicted protein SSDG_07511 Streptomyces pristinaespiralis ATCC 25486
3
O54259_STRNO
(O54259)
Jump to Nogl_00350
[query] 39 - 127 (139)
[subject] 14 - 102 (118)
5e-22 107   58% SnoaB SnoaB Streptomyces nogalater
4
Q8VWB4_9ACTO
(Q8VWB4)
[query] 34 - 131 (139)
[subject] 9 - 106 (122)
4e-21 104   53% AknX aknX Streptomyces galilaeus
5
Q9L552_9ACTO
(Q9L552)
Jump to Acla_00060
[query] 34 - 131 (139)
[subject] 9 - 106 (122)
6e-21 104   53% AknX aknX Streptomyces galilaeus
6
B5G887_9ACTO
(B5G887)
[query] 38 - 129 (139)
[subject] 14 - 105 (118)
1e-20 103   53% Antibiotic biosynthesis monooxygenase subfamily SSBG_00495 Streptomyces sp. SPB74
7
Q4R0L6_STRCX
(Q4R0L6)
Jump to Chart_00160
[query] 38 - 125 (139)
[subject] 6 - 93 (106)
2e-20 102   55% ChaH protein chaH Streptomyces chartreusis
8
Q67G52_9ACTO
(Q67G52)
Jump to Heda_00060
[query] 39 - 126 (139)
[subject] 11 - 98 (115)
2e-18 95.9 48% Anthrone oxygenase Streptomyces griseoruber
9
Q2PZS0_9ACTO
(Q2PZS0)
Jump to Cosmo_00060
[query] 40 - 126 (139)
[subject] 21 - 107 (117)
3e-17 91.7 51% CosX cosX Streptomyces olindensis
10
E8RWT7_MICSL
(E8RWT7)
[query] 39 - 125 (139)
[subject] 13 - 99 (107)
4e-15 85.1 53% Antibiotic biosynthesis monooxygenase ML5_4426 Micromonospora sp. (strain L5)
11
D9T292_MICAI
(D9T292)
[query] 39 - 125 (139)
[subject] 13 - 99 (107)
4e-15 85.1 53% Antibiotic biosynthesis monooxygenase Micau_3995 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
12
D1A6U1_THECD
(D1A6U1)
[query] 39 - 125 (139)
[subject] 171 - 257 (269)
4e-15 84.7 51% Antibiotic biosynthesis monooxygenase Tcur_2800 Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081)
13
Q54813_STRPE
(Q54813)
Jump to Adria_00260
[query] 39 - 137 (139)
[subject] 14 - 119 (129)
5e-14 81.3 45% Anthraquinol monooxygenase Streptomyces peucetius
14
Q2PA06_9ACTO
(Q2PA06)
Jump to Stref_00090
[query] 38 - 125 (139)
[subject] 13 - 102 (111)
5e-14 81.3 40% Monooxygenase stfOI Streptomyces steffisburgensis
15
Q55222_STRSQ
(Q55222)
Jump to Dauno_00150
[query] 39 - 137 (139)
[subject] 18 - 121 (131)
1e-13 79.7 44% Oxygenase dauA Streptomyces sp
16
E8W960_STRFA
(E8W960)
[query] 38 - 131 (139)
[subject] 520 - 615 (615)
3e-13 79   38% AMP-dependent synthetase and ligase Sfla_5326 Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD)
17
Q3S8Q8_STRRM
(Q3S8Q8)
Jump to Oxtet_00080
[query] 38 - 126 (139)
[subject] 1 - 89 (95)
9e-12 73.9 40% OxyG oxyG Streptomyces rimosus
18
Q194R0_STRAA
(Q194R0)
Jump to Mith_00100
[query] 38 - 130 (139)
[subject] 1 - 93 (99)
9e-10 67   35% Oxygenase mtmOIII Streptomyces argillaceus
19
C0JWC9_9ACTO
(C0JWC9)
Jump to Polk_00340
[query] 32 - 125 (139)
[subject] 9 - 102 (109)
5e-09 64.7 33% PokO3 pokO3 Streptomyces diastatochromogenes
20
D9UBK9_STRPR
(D9UBK9)
[query] 38 - 125 (139)
[subject] 1 - 88 (103)
8e-08 60.5 34% Putative oxygenase c104_05c Streptomyces pristinaespiralis
21
B5HJX8_STRPR
(B5HJX8)
[query] 38 - 125 (139)
[subject] 1 - 88 (103)
8e-08 60.5 34% Oxygenase SSDG_05475 Streptomyces pristinaespiralis ATCC 25486
22
D7BZR9_STRBB
(D7BZR9)
[query] 36 - 121 (139)
[subject] 564 - 651 (766)
1e-05 53.1 33% Acyl-CoA ligase SBI_06854 Streptomyces bingchenggensis (strain BCW-1)
23
O68922_9ACTO
(O68922)
Jump to Fren_00210
[query] 38 - 125 (139)
[subject] 6 - 93 (108)
4e-05 51.6 33% Quinone-forming monooxygenase frnU Streptomyces roseofulvus
24
D9UKP1_9ACTO
(D9UKP1)
[query] 38 - 125 (139)
[subject] 6 - 93 (108)
4e-05 51.6 33% Quinone-forming monooxygenase SSLG_05757 Streptomyces sp. SPB78
25
F8B4X7_9ACTO
(F8B4X7)
[query] 49 - 116 (139)
[subject] 38 - 108 (825)
0.0001 50.4 37% Pentachlorophenol monooxygenase FsymDg_2766 Frankia symbiont of Datisca glomerata 1.14.13.50
26
D6AM74_STRFL
(D6AM74)
[query] 39 - 134 (139)
[subject] 16 - 118 (118)
0.0002 49.7 30% Monooxygenase SSGG_02810 Streptomyces roseosporus NRRL 15998
27
D7BZS2_STRBB
(D7BZS2)
[query] 39 - 107 (139)
[subject] 11 - 83 (214)
0.0002 49.3 38% Putative uncharacterized protein SBI_06857 Streptomyces bingchenggensis (strain BCW-1)
28
Q8XYB2_RALSO
(Q8XYB2)
[query] 39 - 129 (139)
[subject] 24 - 115 (164)
0.0003 48.9 34% Hypothetical transmembrane protein RSc1850 Ralstonia solanacearum
Pseudomonas solanacearum
29
B1VTB6_STRGG
(B1VTB6)
[query] 39 - 134 (139)
[subject] 16 - 118 (118)
0.0006 47.8 29% Putative monooxygenase SGR_4177 Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
30
B8G899_CHLAD
(B8G899)
[query] 38 - 112 (139)
[subject] 1 - 77 (120)
0.001 47   39% Antibiotic biosynthesis monooxygenase Cagg_3305 Chloroflexus aggregans (strain MD-66 / DSM 9485)
accessionDBtoolalignmentEvalueScoreIdent.linkinformationpubmed
1
D9UBN4_STRPR
(D9UBN4)
[query] 38 - 131 (139)
[subject] 1 - 94 (97)
7e-24 114   59%
Product
Putative oxygenase
Gene
c101_13
Organism
Streptomyces pristinaespiralis
1uniprot[Pubmed] 21342465
Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis.(Microb Biotechnol) [2011]
3
O54259_STRNO
(O54259)
Jump to Nogl_00350
[query] 39 - 127 (139)
[subject] 14 - 102 (118)
5e-22 107   58%
Product
SnoaB
Gene
SnoaB
Organism
Streptomyces nogalater
1uniprot[Pubmed] 8668120 [Medline] 96242142
A gene cluster involved in nogalamycin biosynthesis from Streptomyces nogalater: sequence analysis and complementation of early-block mutations in the anthracycline pathway.(Mol. Gen. Genet.) [1996]
2uniprot[Pubmed] 9349712 [Medline] 98007868
Characterization of Streptomyces nogalater genes encoding enzymes involved in glycosylation steps in nogalamycin biosynthesis.(Mol. Gen. Genet.) [1997]
3uniprot[Pubmed] 8760909 [Medline] 96349102
Production of hybrid anthracycline antibiotics by heterologous expression of Streptomyces nogalater nogalamycin biosynthesis genes.(Microbiology) [1996]
4uniprot[Pubmed] 20052967
Crystal structure of the cofactor-independent monooxygenase SnoaB from Streptomyces nogalater: implications for the reaction mechanism.(Biochemistry) [2010]
[pubmed all]
4
Q8VWB4_9ACTO
(Q8VWB4)
[query] 34 - 131 (139)
[subject] 9 - 106 (122)
4e-21 104   53%
Product
AknX
Gene
aknX
Organism
Streptomyces galilaeus
1uniprot[Pubmed] 12399480 [Medline] 22286521
Expression, purification, and characterization of AknX anthrone oxygenase, which is involved in aklavinone biosynthesis in Streptomyces galilaeus.(J. Bacteriol.) [2002]
5
Q9L552_9ACTO
(Q9L552)
Jump to Acla_00060
[query] 34 - 131 (139)
[subject] 9 - 106 (122)
6e-21 104   53%
Product
AknX
Gene
aknX
Organism
Streptomyces galilaeus
1uniprot[Pubmed] 12137949 [Medline] 22133312
Cloning and characterization of Streptomyces galilaeus aclacinomycins polyketide synthase (PKS) cluster.(Gene) [2002]
7
Q4R0L6_STRCX
(Q4R0L6)
Jump to Chart_00160
[query] 38 - 125 (139)
[subject] 6 - 93 (106)
2e-20 102   55%
Product
ChaH protein
Gene
chaH
Organism
Streptomyces chartreusis
1uniprot[Pubmed] 15911378
Biosynthesis of the antitumor agent chartreusin involves the oxidative rearrangement of an anthracyclic polyketide.(Chem. Biol.) [2005]
8
Q67G52_9ACTO
(Q67G52)
Jump to Heda_00060
[query] 39 - 126 (139)
[subject] 11 - 98 (115)
2e-18 95.9 48%
Product
Anthrone oxygenase
Gene
 
Organism
Streptomyces griseoruber
1uniprot[Pubmed] 15271354
The hedamycin locus implicates a novel aromatic PKS priming mechanism.(Chem. Biol.) [2004]
9
Q2PZS0_9ACTO
(Q2PZS0)
Jump to Cosmo_00060
[query] 40 - 126 (139)
[subject] 21 - 107 (117)
3e-17 91.7 51%
Product
CosX
Gene
cosX
Organism
Streptomyces olindensis
1uniprot[Pubmed] 16810496
Insights in the glycosylation steps during biosynthesis of the antitumor anthracycline cosmomycin: characterization of two glycosyltransferase genes.(Appl. Microbiol. Biotechnol.) [2006]
12
D1A6U1_THECD
(D1A6U1)
[query] 39 - 125 (139)
[subject] 171 - 257 (269)
4e-15 84.7 51%
Product
Antibiotic biosynthesis monooxygenase
Gene
Tcur_2800
Organism
Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081)
1uniprot
Complete genome sequence of Thermomonospora curvata type strain (B9).(Stand. Genomic Sci.) [2011]
13
Q54813_STRPE
(Q54813)
Jump to Adria_00260
[query] 39 - 137 (139)
[subject] 14 - 119 (129)
5e-14 81.3 45%
Product
Anthraquinol monooxygenase
Gene
 
Organism
Streptomyces peucetius
1uniprot[Pubmed] 7828855 [Medline] 95129838
Characterization of the Streptomyces peucetius ATCC 29050 genes encoding doxorubicin polyketide synthase.(Gene) [1994]
14
Q2PA06_9ACTO
(Q2PA06)
Jump to Stref_00090
[query] 38 - 125 (139)
[subject] 13 - 102 (111)
5e-14 81.3 40%
Product
Monooxygenase
Gene
stfOI
Organism
Streptomyces steffisburgensis
1uniprot[Pubmed] 16751529
Isolation, characterization, and heterologous expression of the biosynthesis gene cluster for the antitumor anthracycline steffimycin.(Appl. Environ. Microbiol.) [2006]
15
Q55222_STRSQ
(Q55222)
Jump to Dauno_00150
[query] 39 - 137 (139)
[subject] 18 - 121 (131)
1e-13 79.7 44%
Product
Oxygenase
Gene
dauA
Organism
Streptomyces sp
1uniprot[Pubmed] 7928998 [Medline] 95014072
Isolation and sequence analysis of polyketide synthase genes from the daunomycin-producing Streptomyces sp. strain C5.(J. Bacteriol.) [1994]
17
Q3S8Q8_STRRM
(Q3S8Q8)
Jump to Oxtet_00080
[query] 38 - 126 (139)
[subject] 1 - 89 (95)
9e-12 73.9 40%
Product
OxyG
Gene
oxyG
Organism
Streptomyces rimosus
1uniprot[Pubmed] 16597959
Engineered biosynthesis of a novel amidated polyketide, using the malonamyl-specific initiation module from the oxytetracycline polyketide synthase.(Appl. Environ. Microbiol.) [2006]
18
Q194R0_STRAA
(Q194R0)
Jump to Mith_00100
[query] 38 - 130 (139)
[subject] 1 - 93 (99)
9e-10 67   35%
Product
Oxygenase
Gene
mtmOIII
Organism
Streptomyces argillaceus
1uniprot[Pubmed] 8654997 [Medline] 96257259
Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin.(Gene) [1996]
2uniprot[Pubmed] 8757400 [Medline] 96335144
An ABC transporter is essential for resistance to the antitumor agent mithramycin in the producer Streptomyces argillaceus.(Mol. Gen. Genet.) [1996]
3uniprot[Pubmed] 9150235 [Medline] 97294479
Cloning and insertional inactivation of Streptomyces argillaceus genes involved in the earliest steps of biosynthesis of the sugar moieties of the antitumor polyketide mithramycin.(J. Bacteriol.) [1997]
4uniprot[Pubmed] 9733697 [Medline] 98406047
Identification of two genes from Streptomyces argillaceus encoding glycosyltransferases involved in transfer of a disaccharide during biosynthesis of the antitumor drug mithramycin.(J. Bacteriol.) [1998]
5uniprot[Pubmed] 10102355 [Medline] 99200478
Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus.(Mol. Gen. Genet.) [1999]
6uniprot[Pubmed] 9889148 [Medline] 99111236
Oxidative cleavage of premithramycin B is one of the last steps in the biosynthesis of the antitumor drug mithramycin.(Chem. Biol.) [1999]
7uniprot[Pubmed] 10660060 [Medline] 20123456
Characterization of two glycosyltransferases involved in early glycosylation steps during biosynthesis of the antitumor polyketide mithramycin by Streptomyces argillaceus.(Mol. Gen. Genet.) [2000]
8uniprot[Pubmed] 11254130 [Medline] 21148776
The mtmVUC genes of the mithramycin gene cluster in Streptomyces argillaceus are involved in the biosynthesis of the sugar moieties.(Mol. Gen. Genet.) [2001]
9uniprot[Pubmed] 12733914 [Medline] 22619809
Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesis.(J. Am. Chem. Soc.) [2003]
10uniprot[Pubmed] 9917296 [Medline] 99115752
The structure of mithramycin reinvestigated.(J. Nat. Prod.) [1999]
11uniprot[Pubmed] 11853433 [Medline] 21843297
Ketopremithramycins and ketomithramycins, four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces argillaceus, reveal novel insights into post-PKS tailoring steps of the mithramycin biosynthetic pathway.(J. Am. Chem. Soc.) [2002]
12uniprot[Pubmed] 10652287 [Medline] 20119254
Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus.(J. Biol. Chem.) [2000]
13uniprot[Pubmed] 10779713 [Medline] 20243461
Insertional inactivation of mtrX and mtrY genes from the mithramycin gene cluster affects production and growth of the producer organism Streptomyces argillaceus.(FEMS Microbiol. Lett.) [2000]
14uniprot[Pubmed] 12022840 [Medline] 22017994
Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways.(J. Am. Chem. Soc.) [2002]
15uniprot[Pubmed] 12813091 [Medline] 22697398
Purification and characterization of a monooxygenase involved in the biosynthetic pathway of the antitumor drug mithramycin.(J. Bacteriol.) [2003]
16uniprot[Pubmed] 8807845 [Medline] 97113238
Deciphering the biosynthetic origin of the aglycone of the aureolic acid group of anti-tumor agents.(Chem. Biol.) [1996]
17uniprot[Pubmed] 14660589
MtmMII-mediated C-methylation during biosynthesis of the antitumor drug mithramycin is essential for biological activity and DNA-drug interaction.(J. Biol. Chem.) [2004]
18uniprot[Pubmed] 9375253 [Medline] 98042823
Folding of the polyketide chain is not dictated by minimal polyketide synthase in the biosynthesis of mithramycin and anthracycline.(Chem. Biol.) [1997]
19uniprot[Pubmed] 15712316
Elucidation of the glycosylation sequence of mithramycin biosynthesis: isolation of 3A-deolivosylpremithramycin B and its conversion to premithramycin B by glycosyltransferase MtmGII.(Chembiochem) [2005]
20uniprot[Pubmed] 10760873
The Novel Hybrid Antitumor Compound Premithramycinone H Provides Indirect Evidence for a Tricyclic Intermediate of the Biosynthesis of the Aureolic Acid Antibiotic Mithramycin.(Angew. Chem. Int. Ed.) [2000]
[pubmed all]
19
C0JWC9_9ACTO
(C0JWC9)
Jump to Polk_00340
[query] 32 - 125 (139)
[subject] 9 - 102 (109)
5e-09 64.7 33%
Product
PokO3
Gene
pokO3
Organism
Streptomyces diastatochromogenes
1uniprot[Pubmed] 19266534
Organisation of the Biosynthetic Gene Cluster and Tailoring Enzymes in the Biosynthesis of the Tetracyclic Quinone Glycoside Antibiotic Polyketomycin.(Chembiochem) [2009]
20
D9UBK9_STRPR
(D9UBK9)
[query] 38 - 125 (139)
[subject] 1 - 88 (103)
8e-08 60.5 34%
Product
Putative oxygenase
Gene
c104_05c
Organism
Streptomyces pristinaespiralis
1uniprot[Pubmed] 21342465
Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis.(Microb Biotechnol) [2011]
22
D7BZR9_STRBB
(D7BZR9)
[query] 36 - 121 (139)
[subject] 564 - 651 (766)
1e-05 53.1 33%
Product
Acyl-CoA ligase
Gene
SBI_06854
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
23
O68922_9ACTO
(O68922)
Jump to Fren_00210
[query] 38 - 125 (139)
[subject] 6 - 93 (108)
4e-05 51.6 33%
Product
Quinone-forming monooxygenase
Gene
frnU
Organism
Streptomyces roseofulvus
1uniprot[Pubmed] 8181754 [Medline] 94237486
Cloning, sequencing and deduced functions of a cluster of Streptomyces genes probably encoding biosynthesis of the polyketide antibiotic frenolicin.(Gene) [1994]
27
D7BZS2_STRBB
(D7BZS2)
[query] 39 - 107 (139)
[subject] 11 - 83 (214)
0.0002 49.3 38%
Product
Putative uncharacterized protein
Gene
SBI_06857
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
28
Q8XYB2_RALSO
(Q8XYB2)
[query] 39 - 129 (139)
[subject] 24 - 115 (164)
0.0003 48.9 34%
Product
Hypothetical transmembrane protein
Gene
RSc1850
Organism
Ralstonia solanacearum
Pseudomonas solanacearum
1uniprot[Pubmed] 11823852 [Medline] 21681879
Genome sequence of the plant pathogen Ralstonia solanacearum.(Nature) [2002]
29
B1VTB6_STRGG
(B1VTB6)
[query] 39 - 134 (139)
[subject] 16 - 118 (118)
0.0006 47.8 29%
Product
Putative monooxygenase
Gene
SGR_4177
Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]