BLAST table : Asco_00140

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1
Q9KIE0_STRHY
(Q9KIE0)
[query] 1 - 7525 (7525)
[subject] 1 - 7525 (7525)
0.0 14670   100% FkbB fkbB Streptomyces hygroscopicus subsp. ascomyceticus
2
E9KTB5_STRKN
(E9KTB5)
[query] 13 - 7525 (7525)
[subject] 1 - 7591 (7591)
0.0 11530   82% Polyketide synthase fkbB
Tcs_SK_031
Streptomyces kanamyceticus
3
Q9ZGA4_9ACTO
(Q9ZGA4)
[query] 1 - 7525 (7525)
[subject] 1 - 7576 (7576)
0.0 11260   80% FK506 polyketide synthase fkbB Streptomyces sp. MA6548
4
F1D8Z6_9ACTO
(F1D8Z6)
[query] 1 - 7525 (7525)
[subject] 1 - 7655 (7655)
0.0 10870   78% FkbB Streptomyces sp. MJM7001
5
E9KTI2_9ACTO
(E9KTI2)
[query] 10 - 7525 (7525)
[subject] 1 - 7646 (7646)
0.0 10850   78% Polyketide synthase fkbB
Tcs_11604BP_028
Streptomyces sp. KCTC 11604BP
6
Q54296_STRHY
(Q54296)
Jump to Rapam_00110
[query] 2408 - 7480 (7525)
[subject] 4876 - 10151 (10223)
(7 hsp)
0.0 4748   53% Polyketide synthase rapB Streptomyces hygroscopicus
7
D7BRD4_STRBB
(D7BRD4)
[query] 1072 - 7166 (7525)
[subject] 2723 - 9353 (9950)
(11 hsp)
0.0 4603   47% Short-chain dehydrogenase/reductase SDR SBI_01976 Streptomyces bingchenggensis (strain BCW-1)
8
C6WNW1_ACTMD
(C6WNW1)
[query] 1050 - 7473 (7525)
[subject] 7 - 7031 (7110)
(4 hsp)
0.0 4502   45% Short-chain dehydrogenase/reductase SDR Amir_2695 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
9
Q6W5Q0_9ACTO
(Q6W5Q0)
Jump to FR008_00160
[query] 1161 - 7188 (7525)
[subject] 35 - 6533 (10625)
(18 hsp)
0.0 4349   46% FscC fscC Streptomyces sp. FR-008
10
D9T6W4_MICAI
(D9T6W4)
[query] 1067 - 6809 (7525)
[subject] 1493 - 7720 (9936)
(22 hsp)
0.0 4316   47% Beta-ketoacyl synthase Micau_2464 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
11
E8S0C5_MICSL
(E8S0C5)
[query] 1067 - 6809 (7525)
[subject] 1493 - 7721 (9937)
(22 hsp)
0.0 4315   47% Beta-ketoacyl synthase ML5_5898 Micromonospora sp. (strain L5)
12
B3TMQ7_9ACTO
(B3TMQ7)
[query] 1159 - 7475 (7525)
[subject] 34 - 6804 (6872)
(5 hsp)
0.0 4285   44% Polyketide synthase KijS2 Actinomadura kijaniata
13
Q6MZ72_MYCUA
(Q6MZ72)
Jump to MUP_00320
[query] 1094 - 7095 (7525)
[subject] 6621 - 13299 (14130)
(23 hsp)
0.0 4126   42% Type I modular polyketide synthase mlsB
MUP032c
Mycobacterium ulcerans (strain Agy99)
14
Q54299_STRHY
(Q54299)
Jump to Rapam_00140
[query] 2749 - 7223 (7525)
[subject] 23 - 4497 (6260)
(15 hsp)
0.0 4124   54% Polyketide synthase rapC Streptomyces hygroscopicus
15
C6K7D8_9ACTO
(C6K7D8)
[query] 2423 - 7524 (7525)
[subject] 2788 - 7935 (7938)
(10 hsp)
0.0 3979   48% Polyketide synthase rapA Actinoplanes sp. N902-109
16
A4X8L0_SALTO
(A4X8L0)
[query] 1059 - 5946 (7525)
[subject] 1802 - 7130 (7210)
(4 hsp)
0.0 3921   48% Beta-ketoacyl synthase Strop_2768 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
17
F8QPF9_9ACTO
(F8QPF9)
[query] 1161 - 5945 (7525)
[subject] 35 - 5259 (5339)
(9 hsp)
0.0 3800   47% Polyketide synthase natB Streptomyces sp. CS
18
Q82QT4_STRAW
(Q82QT4)
[query] 2350 - 7470 (7525)
[subject] 2095 - 7658 (7746)
(13 hsp)
0.0 3732   46% Modular polyketide synthase pteA1
SAV419
SAV_419
Streptomyces avermitilis
19
F8QPG0_9ACTO
(F8QPG0)
[query] 1161 - 5953 (7525)
[subject] 31 - 5248 (5321)
(5 hsp)
0.0 3729   48% Polyketide synthase natC Streptomyces sp. CS
20
E0L044_STRVO
(E0L044)
[query] 1050 - 5945 (7525)
[subject] 1736 - 7143 (7224)
(9 hsp)
0.0 3714   46% Beta-ketoacyl synthase StrviDRAFT_8272 Streptomyces violaceusniger Tu 4113
21
B3TMQ8_9ACTO
(B3TMQ8)
[query] 1074 - 5946 (7525)
[subject] 926 - 6168 (6241)
(11 hsp)
0.0 3710   47% Polyketide synthase KijS1 Actinomadura kijaniata
22
Q6JHN7_9PSEU
(Q6JHN7)
[query] 1159 - 5941 (7525)
[subject] 33 - 5101 (5176)
(5 hsp)
0.0 3707   47% ObsB Saccharopolyspora spinosa
23
F1CLC1_9ACTO
(F1CLC1)
[query] 1068 - 5946 (7525)
[subject] 1480 - 6744 (6831)
(8 hsp)
0.0 3682   46% ScnS1 scnS1 Streptomyces chattanoogensis
24
Q9X993_9ACTO
(Q9X993)
Jump to Pimar_00170
[query] 1031 - 5946 (7525)
[subject] 1426 - 6710 (6797)
(9 hsp)
0.0 3669   47% PimS1 protein
Polyketide synthase
pimS1 Streptomyces natalensis
25
Q93NW6_9ACTO
(Q93NW6)
Jump to Amph_00170
[query] 1067 - 5945 (7525)
[subject] 5473 - 10833 (10917)
(13 hsp)
0.0 3629   46% AmphC amphC Streptomyces nodosus
26
D8HZ83_AMYMU
(D8HZ83)
[query] 1161 - 5945 (7525)
[subject] 35 - 5005 (5060)
(6 hsp)
0.0 3628   47% Rifamycin polyketide synthase rifB
AMED_0618
Amycolatopsis mediterranei (strain U-32)
27
O52789_AMYMD
(O52789)
[query] 1161 - 5945 (7525)
[subject] 44 - 5014 (5069)
(6 hsp)
0.0 3625   47% Rifamycin polyketide synthase, type 1 Amycolatopsis mediterranei
Nocardia mediterranei
28
O52545_AMYMD
(O52545)
Jump to Rifam_00220
[query] 1161 - 5945 (7525)
[subject] 35 - 5005 (5060)
(6 hsp)
0.0 3624   48% RifB rifB Amycolatopsis mediterranei
Nocardia mediterranei
29
A8M6C7_SALAI
(A8M6C7)
[query] 1154 - 5952 (7525)
[subject] 28 - 5188 (5255)
(7 hsp)
0.0 3624   47% Beta-ketoacyl synthase Sare_1247 Salinispora arenicola (strain CNS-205)
30
B4VDY6_9ACTO
(B4VDY6)
[query] 2759 - 7190 (7525)
[subject] 18 - 4841 (4894)
(6 hsp)
0.0 3613   48% Polyketide synthase type I SSAG_05828 Streptomyces sp. Mg1
31
A1YAN0_AMYOR
(A1YAN0)
[query] 1161 - 5987 (7525)
[subject] 34 - 5053 (5099)
(5 hsp)
0.0 3596   47% Polyketide synthase type I Amycolatopsis orientalis
Nocardia orientalis
32
D2CKM4_PSEAH
(D2CKM4)
[query] 1060 - 5945 (7525)
[subject] 5473 - 10788 (10876)
(15 hsp)
0.0 3566   47% CppC cppC Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
33
Q6JHN8_9PSEU
(Q6JHN8)
[query] 1075 - 5941 (7525)
[subject] 901 - 5970 (6078)
(8 hsp)
0.0 3564   46% ObsA Saccharopolyspora spinosa
34
C0SMW4_9ACTO
(C0SMW4)
Jump to Tauto_00110
[query] 2470 - 7169 (7525)
[subject] 3484 - 8449 (10827)
(23 hsp)
0.0 3533   47% Type I modular polyketide synthase ttmJ Streptomyces spiroverticillatus
35
D1XUK5_9ACTO
(D1XUK5)
[query] 1161 - 5954 (7525)
[subject] 34 - 5085 (5157)
(6 hsp)
0.0 3531   48% Short-chain dehydrogenase/reductase SDR SACTEDRAFT_6365 Streptomyces sp. SA3_actE
36
E8WEN5_STRFA
(E8WEN5)
[query] 1161 - 5946 (7525)
[subject] 34 - 5076 (5156)
(5 hsp)
0.0 3524   47% Beta-ketoacyl synthase Sfla_0979 Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD)
37
C6ZCS1_9ACTO
(C6ZCS1)
[query] 2470 - 7228 (7525)
[subject] 3825 - 8785 (9528)
(20 hsp)
0.0 3521   47% Type I modular polyketide synthase ttnA Streptomyces griseochromogenes
38
B5L6K8_MICCH
(B5L6K8)
[query] 1064 - 5946 (7525)
[subject] 917 - 6227 (6305)
(9 hsp)
0.0 3502   45% Putative type I polyketide synthase Micromonospora chalcea
39
A4KCE4_9ACTO
(A4KCE4)
Jump to Tatmc_00080
[query] 2470 - 7228 (7525)
[subject] 3941 - 8905 (9648)
(20 hsp)
0.0 3490   47% Tautomycetin biosynthetic PKS Streptomyces sp. CK4412
40
Q9ALM2_9PSEU
(Q9ALM2)
Jump to Spino_00210
[query] 1161 - 5955 (7525)
[subject] 34 - 5301 (5588)
(6 hsp)
0.0 3479   45% Polyketide synthase extender modules 8-10 spnE Saccharopolyspora spinosa
41
B5L6K9_MICCH
(B5L6K9)
[query] 1073 - 5945 (7525)
[subject] 1646 - 6933 (7007)
(8 hsp)
0.0 3457   45% Putative type I polyketide synthase Micromonospora chalcea
42
C6WNV0_ACTMD
(C6WNV0)
[query] 1161 - 5945 (7525)
[subject] 39 - 5110 (5400)
(4 hsp)
0.0 3439   46% Short-chain dehydrogenase/reductase SDR Amir_2684 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
43
Q9L4W3_9ACTO
(Q9L4W3)
Jump to Nysta_00150
[query] 2767 - 7091 (7525)
[subject] 42 - 4661 (11096)
(23 hsp)
0.0 3353   48% NysC nysC Streptomyces noursei
44
B1W5P4_STRGG
(B1W5P4)
[query] 1137 - 5951 (7525)
[subject] 8 - 4774 (4843)
(5 hsp)
0.0 3347   46% Putative type-I PKS pks3-2
SGR_6372
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
45
Q52V52_9ACTO
(Q52V52)
[query] 2761 - 7131 (7525)
[subject] 35 - 4783 (5432)
(10 hsp)
0.0 3345   47% Polyketide synthase type I Streptomyces aizunensis
46
C3VLY1_9ACTO
(C3VLY1)
[query] 2660 - 7476 (7525)
[subject] 925 - 6303 (6383)
(12 hsp)
0.0 3345   43% Polyketide synthase type I mlaA1 Streptomyces sp. MP39-85
47
D9VEY7_9ACTO
(D9VEY7)
[query] 2683 - 7482 (7525)
[subject] 53 - 5232 (5260)
(3 hsp)
0.0 3344   44% Modular polyketide synthase SSMG_05939 Streptomyces sp. AA4
48
F4F7F4_VERMA
(F4F7F4)
[query] 1071 - 5951 (7525)
[subject] 863 - 5754 (5781)
(10 hsp)
0.0 3285   46% Modular polyketide synthase VAB18032_16435 Verrucosispora maris (strain AB-18-032)
49
A8LUX2_SALAI
(A8LUX2)
[query] 1068 - 5185 (7525)
[subject] 897 - 5199 (7279)
(20 hsp)
0.0 3221   48% Beta-ketoacyl synthase Sare_3156 Salinispora arenicola (strain CNS-205)
50
C0Z477_STRVN
(C0Z477)
[query] 1047 - 5197 (7525)
[subject] 939 - 5386 (6130)
(10 hsp)
0.0 3213   49% Type I polyketide synthase, loading module and modules 1-3 ken16 Streptomyces violaceoruber
accessionDBtoolalignmentEvalueScoreIdent.linkinformationpubmed
1
Q9KIE0_STRHY
(Q9KIE0)
[query] 1 - 7525 (7525)
[subject] 1 - 7525 (7525)
0.0 14670   100%
Product
FkbB
Gene
fkbB
Organism
Streptomyces hygroscopicus subsp. ascomyceticus
1uniprot[Pubmed] 10863099 [Medline] 20323220
The FK520 gene cluster of Streptomyces hygroscopicus var. ascomyceticus (ATCC 14891) contains genes for biosynthesis of unusual polyketide extender units.(Gene) [2000]
2
E9KTB5_STRKN
(E9KTB5)
[query] 13 - 7525 (7525)
[subject] 1 - 7591 (7591)
0.0 11530   82%
Product
Polyketide synthase
Gene
fkbB
Tcs_SK_031
Organism
Streptomyces kanamyceticus
1uniprot[Pubmed] 21175203
Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.(J. Am. Chem. Soc.) [2011]
3
Q9ZGA4_9ACTO
(Q9ZGA4)
[query] 1 - 7525 (7525)
[subject] 1 - 7576 (7576)
0.0 11260   80%
Product
FK506 polyketide synthase
Gene
fkbB
Organism
Streptomyces sp. MA6548
1uniprot[Pubmed] 9780228 [Medline] 98451508
The biosynthetic gene cluster for the macrolactone ring of the immunosuppressant FK506.(Eur. J. Biochem.) [1998]
5
E9KTI2_9ACTO
(E9KTI2)
[query] 10 - 7525 (7525)
[subject] 1 - 7646 (7646)
0.0 10850   78%
Product
Polyketide synthase
Gene
fkbB
Tcs_11604BP_028
Organism
Streptomyces sp. KCTC 11604BP
1uniprot[Pubmed] 21175203
Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.(J. Am. Chem. Soc.) [2011]
6
Q54296_STRHY
(Q54296)
Jump to Rapam_00110
[query] 2408 - 7480 (7525)
[subject] 4876 - 10151 (10223)
(7 hsp)
0.0 4748   53%
Product
Polyketide synthase
Gene
rapB
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]
7
D7BRD4_STRBB
(D7BRD4)
[query] 1072 - 7166 (7525)
[subject] 2723 - 9353 (9950)
(11 hsp)
0.0 4603   47%
Product
Short-chain dehydrogenase/reductase SDR
Gene
SBI_01976
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
8
C6WNW1_ACTMD
(C6WNW1)
[query] 1050 - 7473 (7525)
[subject] 7 - 7031 (7110)
(4 hsp)
0.0 4502   45%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Amir_2695
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
9
Q6W5Q0_9ACTO
(Q6W5Q0)
Jump to FR008_00160
[query] 1161 - 7188 (7525)
[subject] 35 - 6533 (10625)
(18 hsp)
0.0 4349   46%
Product
FscC
Gene
fscC
Organism
Streptomyces sp. FR-008
1uniprot[Pubmed] 14652074
Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003]
12
B3TMQ7_9ACTO
(B3TMQ7)
[query] 1159 - 7475 (7525)
[subject] 34 - 6804 (6872)
(5 hsp)
0.0 4285   44%
Product
Polyketide synthase
Gene
KijS2
Organism
Actinomadura kijaniata
1uniprot[Pubmed] 17985890
Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
13
Q6MZ72_MYCUA
(Q6MZ72)
Jump to MUP_00320
[query] 1094 - 7095 (7525)
[subject] 6621 - 13299 (14130)
(23 hsp)
0.0 4126   42%
Product
Type I modular polyketide synthase
Gene
mlsB
MUP032c
Organism
Mycobacterium ulcerans (strain Agy99)
1uniprot[Pubmed] 14736915
Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans.(Proc. Natl. Acad. Sci. U.S.A.) [2004]
2uniprot[Pubmed] 15758215
Functional analysis and annotation of the virulence plasmid pMUM001 from Mycobacterium ulcerans.(Microbiology) [2005]
[pubmed all]
14
Q54299_STRHY
(Q54299)
Jump to Rapam_00140
[query] 2749 - 7223 (7525)
[subject] 23 - 4497 (6260)
(15 hsp)
0.0 4124   54%
Product
Polyketide synthase
Gene
rapC
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]
17
F8QPF9_9ACTO
(F8QPF9)
[query] 1161 - 5945 (7525)
[subject] 35 - 5259 (5339)
(9 hsp)
0.0 3800   47%
Product
Polyketide synthase
Gene
natB
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
18
Q82QT4_STRAW
(Q82QT4)
[query] 2350 - 7470 (7525)
[subject] 2095 - 7658 (7746)
(13 hsp)
0.0 3732   46%
Product
Modular polyketide synthase
Gene
pteA1
SAV419
SAV_419
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
19
F8QPG0_9ACTO
(F8QPG0)
[query] 1161 - 5953 (7525)
[subject] 31 - 5248 (5321)
(5 hsp)
0.0 3729   48%
Product
Polyketide synthase
Gene
natC
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
21
B3TMQ8_9ACTO
(B3TMQ8)
[query] 1074 - 5946 (7525)
[subject] 926 - 6168 (6241)
(11 hsp)
0.0 3710   47%
Product
Polyketide synthase
Gene
KijS1
Organism
Actinomadura kijaniata
1uniprot[Pubmed] 17985890
Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
22
Q6JHN7_9PSEU
(Q6JHN7)
[query] 1159 - 5941 (7525)
[subject] 33 - 5101 (5176)
(5 hsp)
0.0 3707   47%
Product
ObsB
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
23
F1CLC1_9ACTO
(F1CLC1)
[query] 1068 - 5946 (7525)
[subject] 1480 - 6744 (6831)
(8 hsp)
0.0 3682   46%
Product
ScnS1
Gene
scnS1
Organism
Streptomyces chattanoogensis
1uniprot[Pubmed] 21330439
The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011]
24
Q9X993_9ACTO
(Q9X993)
Jump to Pimar_00170
[query] 1031 - 5946 (7525)
[subject] 1426 - 6710 (6797)
(9 hsp)
0.0 3669   47%
Product
PimS1 protein
Polyketide synthase
Gene
pimS1
Organism
Streptomyces natalensis
1uniprot[Pubmed] 10187796 [Medline] 99214571
The biosynthetic gene cluster for the 26-membered ring polyene macrolide pimaricin. A new polyketide synthase organization encoded by two subclusters separated by functionalization genes.(J. Biol. Chem.) [1999]
2uniprot[Pubmed] 11094342 [Medline] 20547809
A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000]
[pubmed all]
25
Q93NW6_9ACTO
(Q93NW6)
Jump to Amph_00170
[query] 1067 - 5945 (7525)
[subject] 5473 - 10833 (10917)
(13 hsp)
0.0 3629   46%
Product
AmphC
Gene
amphC
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
[pubmed all]
26
D8HZ83_AMYMU
(D8HZ83)
[query] 1161 - 5945 (7525)
[subject] 35 - 5005 (5060)
(6 hsp)
0.0 3628   47%
Product
Rifamycin polyketide synthase
Gene
rifB
AMED_0618
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
28
O52545_AMYMD
(O52545)
Jump to Rifam_00220
[query] 1161 - 5945 (7525)
[subject] 35 - 5005 (5060)
(6 hsp)
0.0 3624   48%
Product
RifB
Gene
rifB
Organism
Amycolatopsis mediterranei
Nocardia mediterranei
1uniprot[Pubmed] 9512878 [Medline] 98174059
Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.(Chem. Biol.) [1998]
2uniprot[Pubmed] 9497318 [Medline] 98165773
3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.(J. Biol. Chem.) [1998]
3uniprot[Pubmed] 11278540 [Medline] 21201076
Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.(J. Biol. Chem.) [2001]
[pubmed all]
31
A1YAN0_AMYOR
(A1YAN0)
[query] 1161 - 5987 (7525)
[subject] 34 - 5053 (5099)
(5 hsp)
0.0 3596   47%
Product
Polyketide synthase type I
Gene
 
Organism
Amycolatopsis orientalis
Nocardia orientalis
1uniprot[Pubmed] 17136886
Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006]
32
D2CKM4_PSEAH
(D2CKM4)
[query] 1060 - 5945 (7525)
[subject] 5473 - 10788 (10876)
(15 hsp)
0.0 3566   47%
Product
CppC
Gene
cppC
Organism
Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
1uniprot[Pubmed] 19697072
Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009]
33
Q6JHN8_9PSEU
(Q6JHN8)
[query] 1075 - 5941 (7525)
[subject] 901 - 5970 (6078)
(8 hsp)
0.0 3564   46%
Product
ObsA
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
34
C0SMW4_9ACTO
(C0SMW4)
Jump to Tauto_00110
[query] 2470 - 7169 (7525)
[subject] 3484 - 8449 (10827)
(23 hsp)
0.0 3533   47%
Product
Type I modular polyketide synthase
Gene
ttmJ
Organism
Streptomyces spiroverticillatus
1uniprot[Pubmed] 16707708
Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 18708355
Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008]
[pubmed all]
37
C6ZCS1_9ACTO
(C6ZCS1)
[query] 2470 - 7228 (7525)
[subject] 3825 - 8785 (9528)
(20 hsp)
0.0 3521   47%
Product
Type I modular polyketide synthase
Gene
ttnA
Organism
Streptomyces griseochromogenes
1uniprot[Pubmed] 19191560
Characterization of the Tautomycetin Biosynthetic Gene Cluster from Streptomyces griseochromogenes Provides New Insight into Dialkylmaleic Anhydride Biosynthesis.(J. Nat. Prod.) [2009]
38
B5L6K8_MICCH
(B5L6K8)
[query] 1064 - 5946 (7525)
[subject] 917 - 6227 (6305)
(9 hsp)
0.0 3502   45%
Product
Putative type I polyketide synthase
Gene
 
Organism
Micromonospora chalcea
1uniprot[Pubmed] 18586939
Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
39
A4KCE4_9ACTO
(A4KCE4)
Jump to Tatmc_00080
[query] 2470 - 7228 (7525)
[subject] 3941 - 8905 (9648)
(20 hsp)
0.0 3490   47%
Product
Tautomycetin biosynthetic PKS
Gene
 
Organism
Streptomyces sp. CK4412
1uniprot[Pubmed] 17379718
Isolation of the biosynthetic gene cluster for tautomycetin, a linear polyketide T cell-specific immunomodulator from Streptomyces sp. CK4412.(Microbiology) [2007]
40
Q9ALM2_9PSEU
(Q9ALM2)
Jump to Spino_00210
[query] 1161 - 5955 (7525)
[subject] 34 - 5301 (5588)
(6 hsp)
0.0 3479   45%
Product
Polyketide synthase extender modules 8-10
Gene
spnE
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 11358695 [Medline] 21257765
Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001]
41
B5L6K9_MICCH
(B5L6K9)
[query] 1073 - 5945 (7525)
[subject] 1646 - 6933 (7007)
(8 hsp)
0.0 3457   45%
Product
Putative type I polyketide synthase
Gene
 
Organism
Micromonospora chalcea
1uniprot[Pubmed] 18586939
Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
42
C6WNV0_ACTMD
(C6WNV0)
[query] 1161 - 5945 (7525)
[subject] 39 - 5110 (5400)
(4 hsp)
0.0 3439   46%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Amir_2684
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
43
Q9L4W3_9ACTO
(Q9L4W3)
Jump to Nysta_00150
[query] 2767 - 7091 (7525)
[subject] 42 - 4661 (11096)
(23 hsp)
0.0 3353   48%
Product
NysC
Gene
nysC
Organism
Streptomyces noursei
1uniprot[Pubmed] 10873841 [Medline] 20334850
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000]
44
B1W5P4_STRGG
(B1W5P4)
[query] 1137 - 5951 (7525)
[subject] 8 - 4774 (4843)
(5 hsp)
0.0 3347   46%
Product
Putative type-I PKS
Gene
pks3-2
SGR_6372
Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]
45
Q52V52_9ACTO
(Q52V52)
[query] 2761 - 7131 (7525)
[subject] 35 - 4783 (5432)
(10 hsp)
0.0 3345   47%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
46
C3VLY1_9ACTO
(C3VLY1)
[query] 2660 - 7476 (7525)
[subject] 925 - 6303 (6383)
(12 hsp)
0.0 3345   43%
Product
Polyketide synthase type I
Gene
mlaA1
Organism
Streptomyces sp. MP39-85
1uniprot[Pubmed] 19854930
Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010]
48
F4F7F4_VERMA
(F4F7F4)
[query] 1071 - 5951 (7525)
[subject] 863 - 5754 (5781)
(10 hsp)
0.0 3285   46%
Product
Modular polyketide synthase
Gene
VAB18032_16435
Organism
Verrucosispora maris (strain AB-18-032)
1uniprot[Pubmed] 21551311
Genome sequence of the abyssomicin- and proximicin-producing marine actinomycete Verrucosispora maris AB-18-032.(J. Bacteriol.) [2011]