BLAST table : Asco_00170

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1
Q9KID7_STRHY
(Q9KID7)
[query] 1 - 6396 (6396)
[subject] 1 - 6396 (6396)
0.0 12570   100% FkbA fkbA Streptomyces hygroscopicus subsp. ascomyceticus
2
E9KTB8_STRKN
(E9KTB8)
[query] 1 - 6396 (6396)
[subject] 1 - 6408 (6408)
0.0 10360   85% Polyketide synthase fkbA
Tcs_SK_034
Streptomyces kanamyceticus
3
P95814_STRSQ
(P95814)
[query] 1 - 6396 (6396)
[subject] 1 - 6420 (6420)
0.0 10060   83% FK506 polyketide synthase fkbA Streptomyces sp
4
E9KTI5_9ACTO
(E9KTI5)
[query] 1 - 6396 (6396)
[subject] 1 - 6418 (6418)
0.0 9829   81% Polyketide synthase fkbA
Tcs_11604BP_031
Streptomyces sp. KCTC 11604BP
5
F1D8Z9_9ACTO
(F1D8Z9)
[query] 1 - 6396 (6396)
[subject] 1 - 6418 (6418)
0.0 9782   81% FkbA Streptomyces sp. MJM7001
6
Q54297_STRHY
(Q54297)
Jump to Rapam_00120
[query] 28 - 6237 (6396)
[subject] 1306 - 7694 (8563)
(10 hsp)
0.0 6000   55% Polyketide synthase rapA Streptomyces hygroscopicus
7
Q54299_STRHY
(Q54299)
Jump to Rapam_00140
[query] 1555 - 6393 (6396)
[subject] 1264 - 6256 (6260)
(6 hsp)
0.0 5041   57% Polyketide synthase rapC Streptomyces hygroscopicus
8
C6K7D8_9ACTO
(C6K7D8)
[query] 28 - 4763 (6396)
[subject] 1215 - 6026 (7938)
(13 hsp)
0.0 4510   55% Polyketide synthase rapA Actinoplanes sp. N902-109
9
Q54296_STRHY
(Q54296)
Jump to Rapam_00110
[query] 27 - 4696 (6396)
[subject] 3263 - 8129 (10223)
(22 hsp)
0.0 4378   53% Polyketide synthase rapB Streptomyces hygroscopicus
10
Q9KIE1_STRHY
(Q9KIE1)
Jump to Asco_00130
[query] 1903 - 5347 (6396)
[subject] 30 - 3516 (3591)
(8 hsp)
0.0 3812   63% FkbC fkbC Streptomyces hygroscopicus subsp. ascomyceticus
11
Q93NW6_9ACTO
(Q93NW6)
Jump to Amph_00170
[query] 1558 - 6236 (6396)
[subject] 1383 - 6451 (10917)
(17 hsp)
0.0 3704   47% AmphC amphC Streptomyces nodosus
12
Q76KY0_STRHA
(Q76KY0)
Jump to Vicen_00200
[query] 30 - 4582 (6396)
[subject] 137 - 5186 (5826)
(14 hsp)
0.0 3631   46% Polyketide synthase modules 1-3 vinP1 Streptomyces halstedii
13
D2CKM4_PSEAH
(D2CKM4)
[query] 30 - 4696 (6396)
[subject] 3524 - 8654 (10876)
(22 hsp)
0.0 3524   47% CppC cppC Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
14
E0L075_STRVO
(E0L075)
[query] 1906 - 6247 (6396)
[subject] 34 - 4771 (5786)
(14 hsp)
0.0 3516   47% Beta-ketoacyl synthase StrviDRAFT_8303 Streptomyces violaceusniger Tu 4113
15
A1YAM7_AMYOR
(A1YAM7)
[query] 1906 - 6237 (6396)
[subject] 39 - 4487 (5723)
(8 hsp)
0.0 3466   48% Polyketide synthase type I Amycolatopsis orientalis
Nocardia orientalis
16
C0SMW2_9ACTO
(C0SMW2)
Jump to Tauto_00090
[query] 1903 - 6236 (6396)
[subject] 32 - 4678 (5770)
(10 hsp)
0.0 3457   47% Type I modular polyketide synthase ttmH Streptomyces spiroverticillatus
17
C0SMW4_9ACTO
(C0SMW4)
Jump to Tauto_00110
[query] 1554 - 6268 (6396)
[subject] 5138 - 10193 (10827)
(23 hsp)
0.0 3449   46% Type I modular polyketide synthase ttmJ Streptomyces spiroverticillatus
18
E9KTB4_STRKN
(E9KTB4)
[query] 1903 - 5354 (6396)
[subject] 30 - 3523 (3597)
(9 hsp)
0.0 3382   57% Polyketide synthase fkbC
Tcs_SK_030
Streptomyces kanamyceticus
19
F1D8Z5_9ACTO
(F1D8Z5)
[query] 1903 - 5347 (6396)
[subject] 37 - 3530 (3605)
(8 hsp)
0.0 3379   57% FkbC Streptomyces sp. MJM7001
20
D7CC08_STRBB
(D7CC08)
[query] 1906 - 6237 (6396)
[subject] 34 - 4774 (5530)
(14 hsp)
0.0 3376   47% Putative type I polyketide synthase pks5-2
SBI_01382
Streptomyces bingchenggensis (strain BCW-1)
21
E9KTI1_9ACTO
(E9KTI1)
[query] 1913 - 5347 (6396)
[subject] 1 - 3484 (3559)
(8 hsp)
0.0 3364   57% Polyketide synthase fkbC
Tcs_11604BP_027
Streptomyces sp. KCTC 11604BP
22
D7F1M1_9ACTO
(D7F1M1)
[query] 1 - 4700 (6396)
[subject] 1 - 5186 (5630)
(9 hsp)
0.0 3333   44% Polyketide synthase tsnAIII Streptomyces longisporoflavus
23
Q6JHN6_9PSEU
(Q6JHN6)
[query] 1904 - 6246 (6396)
[subject] 61 - 4657 (7488)
(18 hsp)
0.0 3325   47% ObsC Saccharopolyspora spinosa
24
E8S0C6_MICSL
(E8S0C6)
[query] 30 - 4273 (6396)
[subject] 2101 - 6802 (7520)
(16 hsp)
0.0 3240   47% Beta-ketoacyl synthase ML5_5899 Micromonospora sp. (strain L5)
25
D9T6W3_MICAI
(D9T6W3)
[query] 30 - 4273 (6396)
[subject] 2101 - 6802 (7520)
(16 hsp)
0.0 3236   47% Acyl transferase Micau_2463 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
26
Q1MX73_9ACTO
(Q1MX73)
Jump to Tetrn_00160
[query] 1 - 4700 (6396)
[subject] 1 - 5208 (5657)
(10 hsp)
0.0 3226   43% Type I polyketide synthase tmnAIV Streptomyces sp. NRRL 11266
27
Q6MZA4_MYCUA
(Q6MZA4)
Jump to MUP_00400
[query] 30 - 4583 (6396)
[subject] 3622 - 8777 (16990)
(29 hsp)
0.0 3211   43% Type I modular polyketide synthase mlsA1
MUP040c
Mycobacterium ulcerans (strain Agy99)
28
C6ZCS0_9ACTO
(C6ZCS0)
[query] 15 - 4282 (6396)
[subject] 2052 - 6654 (7576)
(10 hsp)
0.0 3207   46% Type I modular polyketide synthase ttnB Streptomyces griseochromogenes
29
A4KCE5_9ACTO
(A4KCE5)
Jump to Tatmc_00090
[query] 23 - 4282 (6396)
[subject] 2102 - 6698 (7620)
(10 hsp)
0.0 3199   46% Tautomycetin biosynthetic PKS Streptomyces sp. CK4412
30
Q9KIE0_STRHY
(Q9KIE0)
Jump to Asco_00140
[query] 1589 - 4695 (6396)
[subject] 4068 - 7224 (7525)
(20 hsp)
0.0 2927   55% FkbB fkbB Streptomyces hygroscopicus subsp. ascomyceticus
31
B6ZIR2_STRPT
(B6ZIR2)
Jump to Pladi_00010
[query] 1604 - 5343 (6396)
[subject] 2260 - 6445 (6532)
(17 hsp)
0.0 2880   46% Polyketide synthase pldAI Streptomyces platensis
32
E9KTB5_STRKN
(E9KTB5)
[query] 1584 - 4693 (6396)
[subject] 4101 - 7288 (7591)
(20 hsp)
0.0 2843   54% Polyketide synthase fkbB
Tcs_SK_031
Streptomyces kanamyceticus
33
F1D8Z6_9ACTO
(F1D8Z6)
[query] 1584 - 4695 (6396)
[subject] 4164 - 7349 (7655)
(18 hsp)
0.0 2834   53% FkbB Streptomyces sp. MJM7001
34
E9KTI2_9ACTO
(E9KTI2)
[query] 1584 - 4695 (6396)
[subject] 4155 - 7340 (7646)
(18 hsp)
0.0 2833   53% Polyketide synthase fkbB
Tcs_11604BP_028
Streptomyces sp. KCTC 11604BP
35
C6ZCS1_9ACTO
(C6ZCS1)
[query] 1483 - 5361 (6396)
[subject] 5385 - 9503 (9528)
(21 hsp)
0.0 2759   45% Type I modular polyketide synthase ttnA Streptomyces griseochromogenes
36
D6C477_9ACTO
(D6C477)
Jump to Meili_00310
[query] 1175 - 4696 (6396)
[subject] 1392 - 5348 (5822)
(14 hsp)
0.0 2751   47% Modular polyketide synthase meiA3 Streptomyces nanchangensis
37
A4KCE4_9ACTO
(A4KCE4)
Jump to Tatmc_00080
[query] 1483 - 5361 (6396)
[subject] 5501 - 9623 (9648)
(20 hsp)
0.0 2746   45% Tautomycetin biosynthetic PKS Streptomyces sp. CK4412
38
Q9ZGA4_9ACTO
(Q9ZGA4)
[query] 1584 - 4695 (6396)
[subject] 4098 - 7276 (7576)
(20 hsp)
0.0 2739   52% FK506 polyketide synthase fkbB Streptomyces sp. MA6548
39
Q0QMN5_9ACTO
(Q0QMN5)
[query] 565 - 4272 (6396)
[subject] 682 - 4700 (5393)
(17 hsp)
0.0 2718   47% Polyketide synthase type I Streptomyces sp. Eco86
40
E0KRC6_STRVO
(E0KRC6)
[query] 3018 - 6240 (6396)
[subject] 6938 - 10313 (11118)
(32 hsp)
0.0 2715   50% Beta-ketoacyl synthase StrviDRAFT_5203 Streptomyces violaceusniger Tu 4113
41
D7P611_CHOCO
(D7P611)
[query] 1556 - 5343 (6396)
[subject] 1925 - 6154 (6255)
(19 hsp)
0.0 2694   44% TugA tugA Chondromyces crocatus
42
A0FCL3_STRVO
(A0FCL3)
Jump to Merid_00040
[query] 3099 - 6240 (6396)
[subject] 7067 - 10435 (11604)
(36 hsp)
0.0 2680   49% MerC merC Streptomyces violaceoniger
43
D7CC07_STRBB
(D7CC07)
[query] 1799 - 5347 (6396)
[subject] 943 - 4897 (4979)
(14 hsp)
0.0 2674   46% Putative type I polyketide synthase pks5-1
SBI_01381
Streptomyces bingchenggensis (strain BCW-1)
44
C9YYI2_STRSW
(C9YYI2)
[query] 1904 - 5368 (6396)
[subject] 36 - 3853 (3919)
(8 hsp)
0.0 2667   46% Putative type I polyketide synthase SCAB_83911 Streptomyces scabies (strain 87.22)
Streptomyces scabiei
45
A1YAM6_AMYOR
(A1YAM6)
[query] 1808 - 5345 (6396)
[subject] 33 - 3759 (3834)
(9 hsp)
0.0 2662   47% Polyketide synthase type I Amycolatopsis orientalis
Nocardia orientalis
46
Q52V50_9ACTO
(Q52V50)
[query] 1181 - 4584 (6396)
[subject] 3160 - 6875 (7510)
(21 hsp)
0.0 2651   46% Polyketide synthase type I Streptomyces aizunensis
47
Q1L0T2_STRHY
(Q1L0T2)
[query] 3139 - 6250 (6396)
[subject] 2869 - 6153 (6855)
(13 hsp)
0.0 2636   49% GelA Streptomyces hygroscopicus subsp. duamyceticus
48
Q84G24_STRHY
(Q84G24)
Jump to Gelda2_00080
[query] 3139 - 6250 (6396)
[subject] 2856 - 6140 (6842)
(13 hsp)
0.0 2635   48% GdmAI gdmAI Streptomyces hygroscopicus
49
B5M9K9_STRLS
(B5M9K9)
Jump to Lasal2_00170
[query] 3020 - 6311 (6396)
[subject] 1330 - 4792 (5469)
(13 hsp)
0.0 2628   48% Lasalocid modular polyketide synthase lasAII Streptomyces lasaliensis
50
B6ZK65_STRLS
(B6ZK65)
Jump to Lasal_00140
[query] 3020 - 6311 (6396)
[subject] 1290 - 4752 (5429)
(13 hsp)
0.0 2628   48% Putative polyketide synthase lsd12 Streptomyces lasaliensis
accessionDBtoolalignmentEvalueScoreIdent.linkinformationpubmed
1
Q9KID7_STRHY
(Q9KID7)
[query] 1 - 6396 (6396)
[subject] 1 - 6396 (6396)
0.0 12570   100%
Product
FkbA
Gene
fkbA
Organism
Streptomyces hygroscopicus subsp. ascomyceticus
1uniprot[Pubmed] 10863099 [Medline] 20323220
The FK520 gene cluster of Streptomyces hygroscopicus var. ascomyceticus (ATCC 14891) contains genes for biosynthesis of unusual polyketide extender units.(Gene) [2000]
2
E9KTB8_STRKN
(E9KTB8)
[query] 1 - 6396 (6396)
[subject] 1 - 6408 (6408)
0.0 10360   85%
Product
Polyketide synthase
Gene
fkbA
Tcs_SK_034
Organism
Streptomyces kanamyceticus
1uniprot[Pubmed] 21175203
Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.(J. Am. Chem. Soc.) [2011]
3
P95814_STRSQ
(P95814)
[query] 1 - 6396 (6396)
[subject] 1 - 6420 (6420)
0.0 10060   83%
Product
FK506 polyketide synthase
Gene
fkbA
Organism
Streptomyces sp
1uniprot[Pubmed] 9063448 [Medline] 97217427
Structural organization of a multifunctional polyketide synthase involved in the biosynthesis of the macrolide immunosuppressant FK506.(Eur. J. Biochem.) [1997]
4
E9KTI5_9ACTO
(E9KTI5)
[query] 1 - 6396 (6396)
[subject] 1 - 6418 (6418)
0.0 9829   81%
Product
Polyketide synthase
Gene
fkbA
Tcs_11604BP_031
Organism
Streptomyces sp. KCTC 11604BP
1uniprot[Pubmed] 21175203
Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.(J. Am. Chem. Soc.) [2011]
6
Q54297_STRHY
(Q54297)
Jump to Rapam_00120
[query] 28 - 6237 (6396)
[subject] 1306 - 7694 (8563)
(10 hsp)
0.0 6000   55%
Product
Polyketide synthase
Gene
rapA
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]
7
Q54299_STRHY
(Q54299)
Jump to Rapam_00140
[query] 1555 - 6393 (6396)
[subject] 1264 - 6256 (6260)
(6 hsp)
0.0 5041   57%
Product
Polyketide synthase
Gene
rapC
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]
9
Q54296_STRHY
(Q54296)
Jump to Rapam_00110
[query] 27 - 4696 (6396)
[subject] 3263 - 8129 (10223)
(22 hsp)
0.0 4378   53%
Product
Polyketide synthase
Gene
rapB
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]
10
Q9KIE1_STRHY
(Q9KIE1)
Jump to Asco_00130
[query] 1903 - 5347 (6396)
[subject] 30 - 3516 (3591)
(8 hsp)
0.0 3812   63%
Product
FkbC
Gene
fkbC
Organism
Streptomyces hygroscopicus subsp. ascomyceticus
1uniprot[Pubmed] 10863099 [Medline] 20323220
The FK520 gene cluster of Streptomyces hygroscopicus var. ascomyceticus (ATCC 14891) contains genes for biosynthesis of unusual polyketide extender units.(Gene) [2000]
11
Q93NW6_9ACTO
(Q93NW6)
Jump to Amph_00170
[query] 1558 - 6236 (6396)
[subject] 1383 - 6451 (10917)
(17 hsp)
0.0 3704   47%
Product
AmphC
Gene
amphC
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
[pubmed all]
12
Q76KY0_STRHA
(Q76KY0)
Jump to Vicen_00200
[query] 30 - 4582 (6396)
[subject] 137 - 5186 (5826)
(14 hsp)
0.0 3631   46%
Product
Polyketide synthase modules 1-3
Gene
vinP1
Organism
Streptomyces halstedii
1uniprot[Pubmed] 15112997
Cloning, sequencing, and functional analysis of the biosynthetic gene cluster of macrolactam antibiotic vicenistatin in Streptomyces halstedii.(Chem. Biol.) [2004]
13
D2CKM4_PSEAH
(D2CKM4)
[query] 30 - 4696 (6396)
[subject] 3524 - 8654 (10876)
(22 hsp)
0.0 3524   47%
Product
CppC
Gene
cppC
Organism
Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
1uniprot[Pubmed] 19697072
Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009]
15
A1YAM7_AMYOR
(A1YAM7)
[query] 1906 - 6237 (6396)
[subject] 39 - 4487 (5723)
(8 hsp)
0.0 3466   48%
Product
Polyketide synthase type I
Gene
 
Organism
Amycolatopsis orientalis
Nocardia orientalis
1uniprot[Pubmed] 17136886
Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006]
16
C0SMW2_9ACTO
(C0SMW2)
Jump to Tauto_00090
[query] 1903 - 6236 (6396)
[subject] 32 - 4678 (5770)
(10 hsp)
0.0 3457   47%
Product
Type I modular polyketide synthase
Gene
ttmH
Organism
Streptomyces spiroverticillatus
1uniprot[Pubmed] 16707708
Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 18708355
Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008]
[pubmed all]
17
C0SMW4_9ACTO
(C0SMW4)
Jump to Tauto_00110
[query] 1554 - 6268 (6396)
[subject] 5138 - 10193 (10827)
(23 hsp)
0.0 3449   46%
Product
Type I modular polyketide synthase
Gene
ttmJ
Organism
Streptomyces spiroverticillatus
1uniprot[Pubmed] 16707708
Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 18708355
Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008]
[pubmed all]
18
E9KTB4_STRKN
(E9KTB4)
[query] 1903 - 5354 (6396)
[subject] 30 - 3523 (3597)
(9 hsp)
0.0 3382   57%
Product
Polyketide synthase
Gene
fkbC
Tcs_SK_030
Organism
Streptomyces kanamyceticus
1uniprot[Pubmed] 21175203
Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.(J. Am. Chem. Soc.) [2011]
20
D7CC08_STRBB
(D7CC08)
[query] 1906 - 6237 (6396)
[subject] 34 - 4774 (5530)
(14 hsp)
0.0 3376   47%
Product
Putative type I polyketide synthase
Gene
pks5-2
SBI_01382
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
21
E9KTI1_9ACTO
(E9KTI1)
[query] 1913 - 5347 (6396)
[subject] 1 - 3484 (3559)
(8 hsp)
0.0 3364   57%
Product
Polyketide synthase
Gene
fkbC
Tcs_11604BP_027
Organism
Streptomyces sp. KCTC 11604BP
1uniprot[Pubmed] 21175203
Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.(J. Am. Chem. Soc.) [2011]
23
Q6JHN6_9PSEU
(Q6JHN6)
[query] 1904 - 6246 (6396)
[subject] 61 - 4657 (7488)
(18 hsp)
0.0 3325   47%
Product
ObsC
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
27
Q6MZA4_MYCUA
(Q6MZA4)
Jump to MUP_00400
[query] 30 - 4583 (6396)
[subject] 3622 - 8777 (16990)
(29 hsp)
0.0 3211   43%
Product
Type I modular polyketide synthase
Gene
mlsA1
MUP040c
Organism
Mycobacterium ulcerans (strain Agy99)
1uniprot[Pubmed] 15758215
Functional analysis and annotation of the virulence plasmid pMUM001 from Mycobacterium ulcerans.(Microbiology) [2005]
2uniprot[Pubmed] 14736915
Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans.(Proc. Natl. Acad. Sci. U.S.A.) [2004]
[pubmed all]
28
C6ZCS0_9ACTO
(C6ZCS0)
[query] 15 - 4282 (6396)
[subject] 2052 - 6654 (7576)
(10 hsp)
0.0 3207   46%
Product
Type I modular polyketide synthase
Gene
ttnB
Organism
Streptomyces griseochromogenes
1uniprot[Pubmed] 19191560
Characterization of the Tautomycetin Biosynthetic Gene Cluster from Streptomyces griseochromogenes Provides New Insight into Dialkylmaleic Anhydride Biosynthesis.(J. Nat. Prod.) [2009]
29
A4KCE5_9ACTO
(A4KCE5)
Jump to Tatmc_00090
[query] 23 - 4282 (6396)
[subject] 2102 - 6698 (7620)
(10 hsp)
0.0 3199   46%
Product
Tautomycetin biosynthetic PKS
Gene
 
Organism
Streptomyces sp. CK4412
1uniprot[Pubmed] 17379718
Isolation of the biosynthetic gene cluster for tautomycetin, a linear polyketide T cell-specific immunomodulator from Streptomyces sp. CK4412.(Microbiology) [2007]
2uniprot[Pubmed] 20623733
Biochemical and structural characterization of the tautomycetin thioesterase: analysis of a stereoselective polyketide hydrolase.(Angew. Chem. Int. Ed.) [2010]
[pubmed all]
30
Q9KIE0_STRHY
(Q9KIE0)
Jump to Asco_00140
[query] 1589 - 4695 (6396)
[subject] 4068 - 7224 (7525)
(20 hsp)
0.0 2927   55%
Product
FkbB
Gene
fkbB
Organism
Streptomyces hygroscopicus subsp. ascomyceticus
1uniprot[Pubmed] 10863099 [Medline] 20323220
The FK520 gene cluster of Streptomyces hygroscopicus var. ascomyceticus (ATCC 14891) contains genes for biosynthesis of unusual polyketide extender units.(Gene) [2000]
31
B6ZIR2_STRPT
(B6ZIR2)
Jump to Pladi_00010
[query] 1604 - 5343 (6396)
[subject] 2260 - 6445 (6532)
(17 hsp)
0.0 2880   46%
Product
Polyketide synthase
Gene
pldAI
Organism
Streptomyces platensis
1uniprot[Pubmed] 18997414
Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008]
32
E9KTB5_STRKN
(E9KTB5)
[query] 1584 - 4693 (6396)
[subject] 4101 - 7288 (7591)
(20 hsp)
0.0 2843   54%
Product
Polyketide synthase
Gene
fkbB
Tcs_SK_031
Organism
Streptomyces kanamyceticus
1uniprot[Pubmed] 21175203
Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.(J. Am. Chem. Soc.) [2011]
34
E9KTI2_9ACTO
(E9KTI2)
[query] 1584 - 4695 (6396)
[subject] 4155 - 7340 (7646)
(18 hsp)
0.0 2833   53%
Product
Polyketide synthase
Gene
fkbB
Tcs_11604BP_028
Organism
Streptomyces sp. KCTC 11604BP
1uniprot[Pubmed] 21175203
Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.(J. Am. Chem. Soc.) [2011]
35
C6ZCS1_9ACTO
(C6ZCS1)
[query] 1483 - 5361 (6396)
[subject] 5385 - 9503 (9528)
(21 hsp)
0.0 2759   45%
Product
Type I modular polyketide synthase
Gene
ttnA
Organism
Streptomyces griseochromogenes
1uniprot[Pubmed] 19191560
Characterization of the Tautomycetin Biosynthetic Gene Cluster from Streptomyces griseochromogenes Provides New Insight into Dialkylmaleic Anhydride Biosynthesis.(J. Nat. Prod.) [2009]
36
D6C477_9ACTO
(D6C477)
Jump to Meili_00310
[query] 1175 - 4696 (6396)
[subject] 1392 - 5348 (5822)
(14 hsp)
0.0 2751   47%
Product
Modular polyketide synthase
Gene
meiA3
Organism
Streptomyces nanchangensis
1uniprot[Pubmed] 12811466 [Medline] 22777186
Identification of a gene cluster encoding meilingmycin biosynthesis among multiple polyketide synthase contigs isolated from Streptomyces nanchangensis NS3226.(Arch. Microbiol.) [2003]
2uniprot[Pubmed] 20348291
Cloning of separate meilingmycin biosynthesis gene clusters by use of acyltransferase-ketoreductase didomain PCR amplification.(Appl. Environ. Microbiol.) [2010]
[pubmed all]
37
A4KCE4_9ACTO
(A4KCE4)
Jump to Tatmc_00080
[query] 1483 - 5361 (6396)
[subject] 5501 - 9623 (9648)
(20 hsp)
0.0 2746   45%
Product
Tautomycetin biosynthetic PKS
Gene
 
Organism
Streptomyces sp. CK4412
1uniprot[Pubmed] 17379718
Isolation of the biosynthetic gene cluster for tautomycetin, a linear polyketide T cell-specific immunomodulator from Streptomyces sp. CK4412.(Microbiology) [2007]
38
Q9ZGA4_9ACTO
(Q9ZGA4)
[query] 1584 - 4695 (6396)
[subject] 4098 - 7276 (7576)
(20 hsp)
0.0 2739   52%
Product
FK506 polyketide synthase
Gene
fkbB
Organism
Streptomyces sp. MA6548
1uniprot[Pubmed] 9780228 [Medline] 98451508
The biosynthetic gene cluster for the macrolactone ring of the immunosuppressant FK506.(Eur. J. Biochem.) [1998]
39
Q0QMN5_9ACTO
(Q0QMN5)
[query] 565 - 4272 (6396)
[subject] 682 - 4700 (5393)
(17 hsp)
0.0 2718   47%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces sp. Eco86
1uniprot[Pubmed] 16724457
Isolation and identification of three new 5-alkenyl-3,3(2H)-furanones from two streptomyces species using a genomic screening approach.(J. Antibiot.) [2006]
41
D7P611_CHOCO
(D7P611)
[query] 1556 - 5343 (6396)
[subject] 1925 - 6154 (6255)
(19 hsp)
0.0 2694   44%
Product
TugA
Gene
tugA
Organism
Chondromyces crocatus
1uniprot[Pubmed] 20416506
Biosynthesis of thuggacins in myxobacteria: comparative cluster analysis reveals basis for natural product structural diversity.(Chem. Biol.) [2010]
42
A0FCL3_STRVO
(A0FCL3)
Jump to Merid_00040
[query] 3099 - 6240 (6396)
[subject] 7067 - 10435 (11604)
(36 hsp)
0.0 2680   49%
Product
MerC
Gene
merC
Organism
Streptomyces violaceoniger
1uniprot[Pubmed] 17159202
Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006]
43
D7CC07_STRBB
(D7CC07)
[query] 1799 - 5347 (6396)
[subject] 943 - 4897 (4979)
(14 hsp)
0.0 2674   46%
Product
Putative type I polyketide synthase
Gene
pks5-1
SBI_01381
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
44
C9YYI2_STRSW
(C9YYI2)
[query] 1904 - 5368 (6396)
[subject] 36 - 3853 (3919)
(8 hsp)
0.0 2667   46%
Product
Putative type I polyketide synthase
Gene
SCAB_83911
Organism
Streptomyces scabies (strain 87.22)
Streptomyces scabiei
1uniprot[Pubmed] 20064060
Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010]
45
A1YAM6_AMYOR
(A1YAM6)
[query] 1808 - 5345 (6396)
[subject] 33 - 3759 (3834)
(9 hsp)
0.0 2662   47%
Product
Polyketide synthase type I
Gene
 
Organism
Amycolatopsis orientalis
Nocardia orientalis
1uniprot[Pubmed] 17136886
Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006]
46
Q52V50_9ACTO
(Q52V50)
[query] 1181 - 4584 (6396)
[subject] 3160 - 6875 (7510)
(21 hsp)
0.0 2651   46%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
47
Q1L0T2_STRHY
(Q1L0T2)
[query] 3139 - 6250 (6396)
[subject] 2869 - 6153 (6855)
(13 hsp)
0.0 2636   49%
Product
GelA
Gene
 
Organism
Streptomyces hygroscopicus subsp. duamyceticus
1uniprot[Pubmed] 18600054
Characterization of tailoring genes involved in the modification of geldanamycin polyketide in Streptomyces hygroscopicus JCM4427.(J. Microbiol. Biotechnol.) [2008]
48
Q84G24_STRHY
(Q84G24)
Jump to Gelda2_00080
[query] 3139 - 6250 (6396)
[subject] 2856 - 6140 (6842)
(13 hsp)
0.0 2635   48%
Product
GdmAI
Gene
gdmAI
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 12586396 [Medline] 22474162
Cloning and characterization of a gene cluster for geldanamycin production in Streptomyces hygroscopicus NRRL 3602.(FEMS Microbiol. Lett.) [2003]
50
B6ZK65_STRLS
(B6ZK65)
Jump to Lasal_00140
[query] 3020 - 6311 (6396)
[subject] 1290 - 4752 (5429)
(13 hsp)
0.0 2628   48%
Product
Putative polyketide synthase
Gene
lsd12
Organism
Streptomyces lasaliensis
1uniprot[Pubmed] 19129623
Identification of a gene cluster of polyether antibiotic lasalocid from Streptomyces lasaliensis.(Biosci. Biotechnol. Biochem.) [2009]
2uniprot[Pubmed] 18710235
Epoxide hydrolase Lsd19 for polyether formation in the biosynthesis of lasalocid A: direct experimental evidence on polyene-polyepoxide hypothesis in polyether biosynthesis.(J. Am. Chem. Soc.) [2008]
[pubmed all]