BLAST table : Aver_00030

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function
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accessionDBtoolalignmentEvalueScoreIdent.linkproductgeneorganismec
1
Q9S0N6_STRAW
(Q9S0N6)
[query] 1 - 283 (283)
[subject] 1 - 283 (283)
1e-161 571   100% C5-O-methyltransferase aveD
SAV937
SAV_937
Streptomyces avermitilis
2
A8J700_9ACTO
(A8J700)
[query] 1 - 278 (283)
[subject] 1 - 277 (284)
5e-88 328   61% C5-O-methyltransferase nemD Streptomyces cyaneogriseus subsp. noncyanogenus
3
Q6TKG5_9ACTO
(Q6TKG5)
[query] 14 - 281 (283)
[subject] 12 - 280 (281)
2e-76 290   60% C5-O-methyltransferase milD Streptomyces griseochromogenes
4
B8YGC2_9ACTO
(B8YGC2)
[query] 14 - 281 (283)
[subject] 12 - 280 (281)
5e-76 288   59% C5-O-methyltransferase binD Streptomyces bingchenggensis
5
D7C489_STRBB
(D7C489)
[query] 14 - 281 (283)
[subject] 12 - 280 (286)
6e-76 288   58% C5-O-methyltransferase milD
SBI_00790
Streptomyces bingchenggensis (strain BCW-1)
6
D6C4C6_9ACTO
(D6C4C6)
Jump to Meili_00800
[query] 14 - 282 (283)
[subject] 12 - 281 (286)
2e-75 287   59% C5-O-methyltransferase meiD Streptomyces nanchangensis
7
Q9X5Q9_STRLA
(Q9X5Q9)
[query] 10 - 283 (283)
[subject] 14 - 283 (283)
7e-48 195   42% MitM mitM Streptomyces lavendulae
8
A7NH02_ROSCS
(A7NH02)
[query] 2 - 281 (283)
[subject] 1 - 277 (278)
5e-47 192   42% Methyltransferase type 11 Rcas_0623 Roseiflexus castenholzii (strain DSM 13941 / HLO8)
9
A5UZ15_ROSS1
(A5UZ15)
[query] 6 - 281 (283)
[subject] 5 - 277 (282)
1e-46 191   42% Methyltransferase type 11 RoseRS_3510 Roseiflexus sp. (strain RS-1)
10
E0D208_9ACTO
(E0D208)
Jump to FD891_00070
[query] 12 - 281 (283)
[subject] 15 - 278 (278)
3e-46 189   41% Methyltransferase gfsG Streptomyces graminofaciens
11
D0U2E8_STRPT
(D0U2E8)
[query] 10 - 281 (283)
[subject] 17 - 280 (281)
3e-46 189   42% O-methyl transferase Streptomyces platensis subsp. rosaceus
12
D8HZB5_AMYMU
(D8HZB5)
[query] 8 - 281 (283)
[subject] 2 - 271 (272)
3e-46 189   41% Methyltransferase type 11 AMED_0650 Amycolatopsis mediterranei (strain U-32)
13
O52570_AMYMD
(O52570)
Jump to Rifam_00560
[query] 8 - 281 (283)
[subject] 2 - 271 (272)
4e-46 189   41% C-27 O-methyltransferase Amycolatopsis mediterranei
Nocardia mediterranei
14
Q0H2W9_9ACTO
(Q0H2W9)
[query] 14 - 280 (283)
[subject] 3 - 267 (268)
7e-46 188   42% D-glucose O-methyltransferase atM Actinomadura melliaura
15
A8LFZ5_FRASN
(A8LFZ5)
[query] 9 - 283 (283)
[subject] 4 - 287 (287)
4e-45 186   43% Methyltransferase type 11 Franean1_4832 Frankia sp. (strain EAN1pec)
16
E9KTL3_9ACTO
(E9KTL3)
[query] 15 - 282 (283)
[subject] 6 - 273 (273)
1e-44 184   39% SnogM Tcs_55098_015 Streptomyces sp. ATCC 55098
17
D5SJT8_STRCL
(D5SJT8)
[query] 10 - 281 (283)
[subject] 7 - 275 (283)
1e-43 181   43% Methyltransferase SCLAV_p0694 Streptomyces clavuligerus ATCC 27064
18
B5GND8_STRCL
(B5GND8)
[query] 10 - 281 (283)
[subject] 2 - 270 (278)
1e-43 181   43% NigE SSCG_00862 Streptomyces clavuligerus ATCC 27064
19
Q27W70_STRVO
(Q27W70)
Jump to Niger_00010
[query] 2 - 280 (283)
[subject] 1 - 269 (270)
2e-43 181   40% NigE Streptomyces violaceoniger
20
Q83X76_STRRO
(Q83X76)
[query] 7 - 241 (283)
[subject] 6 - 231 (270)
4e-43 179   44% Putative NDP-hexose 3-O-methyltransferase lkmG Streptomyces rochei
Streptomyces parvullus
21
Q8KZ94_NOCAE
(Q8KZ94)
[query] 10 - 281 (283)
[subject] 14 - 283 (283)
4e-43 179   42% Putative D-glucose O-methyltransferase rebM Lechevalieria aerocolonigenes
Nocardia aerocolonigenes
Saccharothrix aerocolonigenes
22
Q8KI52_NOCAE
(Q8KI52)
[query] 10 - 281 (283)
[subject] 4 - 273 (273)
6e-43 179   42% Methyltransferase
Putative methyltransferase
RebM
rbmF
rebM
Lechevalieria aerocolonigenes
Nocardia aerocolonigenes
Saccharothrix aerocolonigenes
23
E0KNC0_STRVO
(E0KNC0)
[query] 2 - 281 (283)
[subject] 1 - 270 (270)
7e-43 178   39% Methyltransferase type 11 StrviDRAFT_4147 Streptomyces violaceusniger Tu 4113
24
D9WWU0_9ACTO
(D9WWU0)
[query] 2 - 280 (283)
[subject] 1 - 269 (270)
2e-42 177   40% C5-O-methyltransferase SSOG_08430 Streptomyces himastatinicus ATCC 53653
25
E9KTK3_9ACTO
(E9KTK3)
[query] 10 - 280 (283)
[subject] 7 - 275 (276)
1e-41 174   41% Putative D-glucose O-methyltransferase Tcs_55098_005 Streptomyces sp. ATCC 55098
26
A8M6Z4_SALAI
(A8M6Z4)
[query] 10 - 281 (283)
[subject] 4 - 273 (274)
5e-41 172   38% Methyltransferase type 11 Sare_1271 Salinispora arenicola (strain CNS-205)
27
A8M274_SALAI
(A8M274)
[query] 1 - 281 (283)
[subject] 1 - 279 (279)
2e-40 171   38% Methyltransferase type 11 Sare_2332 Salinispora arenicola (strain CNS-205)
28
Q846Y0_STRCM
(Q846Y0)
Jump to Monen_00110
[query] 10 - 281 (283)
[subject] 7 - 276 (276)
4e-40 169   37% Monensin 3-O-methyl transferase monE Streptomyces cinnamonensis
29
B5H2M0_STRCL
(B5H2M0)
[query] 1 - 281 (283)
[subject] 1 - 277 (277)
5e-40 169   42% Methyltransferase SSCG_05830 Streptomyces clavuligerus ATCC 27064
30
D5SL07_STRCL
(D5SL07)
[query] 1 - 281 (283)
[subject] 23 - 299 (299)
1e-39 168   42% Staurosporine biosynthesis methyltransferase StaMA staMA
SCLAV_p1114
Streptomyces clavuligerus ATCC 27064
31
Q83WF7_9ACTO
(Q83WF7)
[query] 2 - 281 (283)
[subject] 1 - 280 (280)
1e-39 168   37% Methyltransferase staMB Streptomyces sp. TP-A0274
32
Q9ALM7_9PSEU
(Q9ALM7)
Jump to Spino_00160
[query] 10 - 281 (283)
[subject] 7 - 273 (275)
3e-39 166   39% Methyltransferase-like protein spnF Saccharopolyspora spinosa
33
Q4JHR3_9PSEU
(Q4JHR3)
[query] 10 - 281 (283)
[subject] 7 - 273 (275)
6e-39 165   37% BusF busF Saccharopolyspora pogona
34
C6W8T2_ACTMD
(C6W8T2)
[query] 10 - 226 (283)
[subject] 9 - 230 (271)
7e-39 165   44% Methyltransferase type 11 Amir_3275 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
35
B5A9R7_9PSEU
(B5A9R7)
[query] 10 - 226 (283)
[subject] 9 - 230 (271)
9e-39 165   44% MbcT mbcT Actinosynnema pretiosum subsp. pretiosum
36
Q83WG2_9ACTO
(Q83WG2)
[query] 6 - 280 (283)
[subject] 3 - 275 (276)
5e-38 162   39% Methyltransferase staMA Streptomyces sp. TP-A0274
37
B4UXS3_9ACTO
(B4UXS3)
[query] 7 - 225 (283)
[subject] 3 - 220 (273)
7e-38 162   42% Methyltransferase SSAG_00429 Streptomyces sp. Mg1
38
Q9X5Q8_STRLA
(Q9X5Q8)
[query] 7 - 281 (283)
[subject] 3 - 274 (275)
1e-37 161   38% MitN mitN Streptomyces lavendulae
39
B5GZG7_STRCL
(B5GZG7)
[query] 7 - 281 (283)
[subject] 9 - 283 (283)
6e-37 159   38% Methyltransferase SCLAV_4762
SSCG_04741
Streptomyces clavuligerus ATCC 27064
40
D5SL02_STRCL
(D5SL02)
[query] 8 - 221 (283)
[subject] 8 - 223 (291)
1e-36 157   43% Staurosporine biosynthesis methyltransferase StaMB staMB
SCLAV_p1109
Streptomyces clavuligerus ATCC 27064
41
F8K389_STRCT
(F8K389)
[query] 19 - 283 (283)
[subject] 16 - 277 (282)
2e-36 157   38% D-glucose O-methyltransferase atM
SCAT_1438
Streptomyces cattleya
42
A4X8P9_SALTO
(A4X8P9)
[query] 15 - 282 (283)
[subject] 12 - 275 (275)
4e-36 156   39% Methyltransferase type 11 Strop_2808 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
43
B5A9R8_9PSEU
(B5A9R8)
[query] 1 - 239 (283)
[subject] 1 - 234 (261)
1e-35 154   41% MbcU mbcU Actinosynnema pretiosum subsp. pretiosum
44
C6W8T1_ACTMD
(C6W8T1)
[query] 10 - 239 (283)
[subject] 3 - 234 (261)
2e-35 153   41% Methyltransferase type 11 Amir_3274 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
45
Q9EYI2_STRNO
(Q9EYI2)
Jump to Nogl_00080
[query] 14 - 281 (283)
[subject] 10 - 276 (278)
3e-35 153   36% SnogM snogM Streptomyces nogalater
46
F8JLJ1_STRCT
(F8JLJ1)
[query] 14 - 280 (283)
[subject] 13 - 277 (284)
8e-33 145   35% D-glucose O-methyltransferase atM
SCAT_p1623
Streptomyces cattleya NRRL 8057
47
D5SKC5_STRCL
(D5SKC5)
[query] 14 - 281 (283)
[subject] 15 - 286 (291)
1e-32 144   34% Methyltransferase type 11 SCLAV_p0882 Streptomyces clavuligerus ATCC 27064
48
B5GMU2_STRCL
(B5GMU2)
[query] 14 - 281 (283)
[subject] 5 - 276 (281)
1e-32 144   34% Methyltransferase type 11 SSCG_00666 Streptomyces clavuligerus ATCC 27064
49
D3D2U8_9ACTO
(D3D2U8)
[query] 15 - 244 (283)
[subject] 12 - 251 (287)
1e-32 144   41% Methyltransferase type 11 FrEUN1fDRAFT_4120 Frankia sp. EUN1f
50
E0KL87_STRVO
(E0KL87)
[query] 4 - 239 (283)
[subject] 1 - 240 (268)
7e-31 139   35% Methyltransferase type 11 StrviDRAFT_3458 Streptomyces violaceusniger Tu 4113
accessionDBtoolalignmentEvalueScoreIdent.linkinformationpubmed
1
Q9S0N6_STRAW
(Q9S0N6)
[query] 1 - 283 (283)
[subject] 1 - 283 (283)
1e-161 571   100%
Product
C5-O-methyltransferase
Gene
aveD
SAV937
SAV_937
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 10449723 [Medline] 99380548
Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis.(Proc. Natl. Acad. Sci. U.S.A.) [1999]
2uniprot[Pubmed] 9469930 [Medline] 98137789
Cloning of the gene encoding avermectin B 5-O-methyltransferase in avermectin-producing Streptomyces avermitilis.(Gene) [1998]
3uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
4uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
3
Q6TKG5_9ACTO
(Q6TKG5)
[query] 14 - 281 (283)
[subject] 12 - 280 (281)
2e-76 290   60%
Product
C5-O-methyltransferase
Gene
milD
Organism
Streptomyces griseochromogenes
1uniprot
Sceening of the gene cluster for milbemycin biosynthesis from Streptomyces griseochromogenes.(Shenyang Yao Ke Da Xue Xue Bao) [2001]
5
D7C489_STRBB
(D7C489)
[query] 14 - 281 (283)
[subject] 12 - 280 (286)
6e-76 288   58%
Product
C5-O-methyltransferase
Gene
milD
SBI_00790
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
6
D6C4C6_9ACTO
(D6C4C6)
Jump to Meili_00800
[query] 14 - 282 (283)
[subject] 12 - 281 (286)
2e-75 287   59%
Product
C5-O-methyltransferase
Gene
meiD
Organism
Streptomyces nanchangensis
1uniprot[Pubmed] 12811466 [Medline] 22777186
Identification of a gene cluster encoding meilingmycin biosynthesis among multiple polyketide synthase contigs isolated from Streptomyces nanchangensis NS3226.(Arch. Microbiol.) [2003]
2uniprot[Pubmed] 20348291
Cloning of separate meilingmycin biosynthesis gene clusters by use of acyltransferase-ketoreductase didomain PCR amplification.(Appl. Environ. Microbiol.) [2010]
[pubmed all]
7
Q9X5Q9_STRLA
(Q9X5Q9)
[query] 10 - 283 (283)
[subject] 14 - 283 (283)
7e-48 195   42%
Product
MitM
Gene
mitM
Organism
Streptomyces lavendulae
1uniprot[Pubmed] 10099135 [Medline] 99201491
Molecular characterization and analysis of the biosynthetic gene cluster for the antitumor antibiotic mitomycin C from Streptomyces lavendulae NRRL 2564.(Chem. Biol.) [1999]
10
E0D208_9ACTO
(E0D208)
Jump to FD891_00070
[query] 12 - 281 (283)
[subject] 15 - 278 (278)
3e-46 189   41%
Product
Methyltransferase
Gene
gfsG
Organism
Streptomyces graminofaciens
1uniprot[Pubmed] 20589823
Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010]
11
D0U2E8_STRPT
(D0U2E8)
[query] 10 - 281 (283)
[subject] 17 - 280 (281)
3e-46 189   42%
Product
O-methyl transferase
Gene
 
Organism
Streptomyces platensis subsp. rosaceus
1uniprot[Pubmed] 19726666
iso-Migrastatin, migrastatin, and dorrigocin production in Streptomyces platensis NRRL 18993 is governed by a single biosynthetic machinery featuring an acyltransferase-less type I polyketide synthase.(J. Biol. Chem.) [2009]
12
D8HZB5_AMYMU
(D8HZB5)
[query] 8 - 281 (283)
[subject] 2 - 271 (272)
3e-46 189   41%
Product
Methyltransferase type 11
Gene
AMED_0650
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
13
O52570_AMYMD
(O52570)
Jump to Rifam_00560
[query] 8 - 281 (283)
[subject] 2 - 271 (272)
4e-46 189   41%
Product
C-27 O-methyltransferase
Gene
 
Organism
Amycolatopsis mediterranei
Nocardia mediterranei
1uniprot[Pubmed] 9512878 [Medline] 98174059
Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.(Chem. Biol.) [1998]
2uniprot[Pubmed] 9497318 [Medline] 98165773
3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.(J. Biol. Chem.) [1998]
3uniprot[Pubmed] 11278540 [Medline] 21201076
Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.(J. Biol. Chem.) [2001]
[pubmed all]
14
Q0H2W9_9ACTO
(Q0H2W9)
[query] 14 - 280 (283)
[subject] 3 - 267 (268)
7e-46 188   42%
Product
D-glucose O-methyltransferase
Gene
atM
Organism
Actinomadura melliaura
1uniprot[Pubmed] 16873021
Deciphering indolocarbazole and enediyne aminodideoxypentose biosynthesis through comparative genomics: insights from the AT2433 biosynthetic locus.(Chem. Biol.) [2006]
15
A8LFZ5_FRASN
(A8LFZ5)
[query] 9 - 283 (283)
[subject] 4 - 287 (287)
4e-45 186   43%
Product
Methyltransferase type 11
Gene
Franean1_4832
Organism
Frankia sp. (strain EAN1pec)
1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]
16
E9KTL3_9ACTO
(E9KTL3)
[query] 15 - 282 (283)
[subject] 6 - 273 (273)
1e-44 184   39%
Product
SnogM
Gene
Tcs_55098_015
Organism
Streptomyces sp. ATCC 55098
1uniprot[Pubmed] 21175203
Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.(J. Am. Chem. Soc.) [2011]
17
D5SJT8_STRCL
(D5SJT8)
[query] 10 - 281 (283)
[subject] 7 - 275 (283)
1e-43 181   43%
Product
Methyltransferase
Gene
SCLAV_p0694
Organism
Streptomyces clavuligerus ATCC 27064
1uniprot
The sequence of a 1.8 Mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010]
19
Q27W70_STRVO
(Q27W70)
Jump to Niger_00010
[query] 2 - 280 (283)
[subject] 1 - 269 (270)
2e-43 181   40%
Product
NigE
Gene
 
Organism
Streptomyces violaceoniger
1uniprot[Pubmed] 17584617
Insights into Polyether Biosynthesis from Analysis of the Nigericin Biosynthetic Gene Cluster in Streptomyces sp. DSM4137.(Chem. Biol.) [2007]
20
Q83X76_STRRO
(Q83X76)
[query] 7 - 241 (283)
[subject] 6 - 231 (270)
4e-43 179   44%
Product
Putative NDP-hexose 3-O-methyltransferase
Gene
lkmG
Organism
Streptomyces rochei
Streptomyces parvullus
1uniprot[Pubmed] 12791134 [Medline] 22676866
The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism.(Mol. Microbiol.) [2003]
2uniprot[Pubmed] 10954087 [Medline] 20408175
Cloning and analysis of the replication origin and the telomeres of the large linear plasmid pSLA2-L in Streptomyces rochei.(Mol. Gen. Genet.) [2000]
3uniprot[Pubmed] 10767533 [Medline] 20231737
Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei.(Gene) [2000]
4uniprot[Pubmed] 9836424 [Medline] 99053144
Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs.(Biosci. Biotechnol. Biochem.) [1998]
[pubmed all]
21
Q8KZ94_NOCAE
(Q8KZ94)
[query] 10 - 281 (283)
[subject] 14 - 283 (283)
4e-43 179   42%
Product
Putative D-glucose O-methyltransferase
Gene
rebM
Organism
Lechevalieria aerocolonigenes
Nocardia aerocolonigenes
Saccharothrix aerocolonigenes
1uniprot[Pubmed] 15743957
Molecular analysis of the rebeccamycin L-amino acid oxidase from Lechevalieria aerocolonigenes ATCC 39243.(J. Bacteriol.) [2005]
2uniprot[Pubmed] 18502766
Structure and mechanism of the rebeccamycin sugar 4'-O-methyltransferase RebM.(J. Biol. Chem.) [2008]
[pubmed all]
22
Q8KI52_NOCAE
(Q8KI52)
[query] 10 - 281 (283)
[subject] 4 - 273 (273)
6e-43 179   42%
Product
Methyltransferase
Putative methyltransferase
RebM
Gene
rbmF
rebM
Organism
Lechevalieria aerocolonigenes
Nocardia aerocolonigenes
Saccharothrix aerocolonigenes
1uniprot[Pubmed] 11983340 [Medline] 21979046
The biosynthetic gene cluster for the antitumor rebeccamycin: characterization and generation of indolocarbazole derivatives.(Chem. Biol.) [2002]
2uniprot[Pubmed] 12619684 [Medline] 22506660
Characterization of the biosynthetic gene cluster of rebeccamycin from Lechevalieria aerocolonigenes ATCC 39243.(Biosci. Biotechnol. Biochem.) [2003]
3uniprot[Pubmed] 14763561
pTOYAMAcos, pTYM18, and pTYM19, actinomycete-Escherichia coli integrating vectors for heterologous gene expression.(J. Antibiot.) [2003]
4uniprot[Pubmed] 12617516 [Medline] 22504382
Cloning of the staurosporine biosynthetic gene cluster from Streptomyces sp. TP-A0274 and its heterologous expression in Streptomyces lividans.(J. Antibiot.) [2002]
5uniprot
Direct formation of chromopyrrolic acid from indole-3-pyruvic acid by StaD, a novel hemoprotein in indolocarbazole biosynthesis.(Tetrahedron Lett.) [2006]
6uniprot
Biosynthesis of heterocyclic antibiotics in actinomycetes and an approach to synthesize the natural compounds.(Nihon Hosenkin Gakkaishi) [2006]
[pubmed all]
25
E9KTK3_9ACTO
(E9KTK3)
[query] 10 - 280 (283)
[subject] 7 - 275 (276)
1e-41 174   41%
Product
Putative D-glucose O-methyltransferase
Gene
Tcs_55098_005
Organism
Streptomyces sp. ATCC 55098
1uniprot[Pubmed] 21175203
Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.(J. Am. Chem. Soc.) [2011]
28
Q846Y0_STRCM
(Q846Y0)
Jump to Monen_00110
[query] 10 - 281 (283)
[subject] 7 - 276 (276)
4e-40 169   37%
Product
Monensin 3-O-methyl transferase
Gene
monE
Organism
Streptomyces cinnamonensis
1uniprot[Pubmed] 12940979 [Medline] 22823264
Analysis of the biosynthetic gene cluster for the polyether antibiotic monensin in Streptomyces cinnamonensis and evidence for the role of monB and monC genes in oxidative cyclization.(Mol. Microbiol.) [2003]
2uniprot
The gene cluster for monensin biosynthesis. [1999]
30
D5SL07_STRCL
(D5SL07)
[query] 1 - 281 (283)
[subject] 23 - 299 (299)
1e-39 168   42%
Product
Staurosporine biosynthesis methyltransferase StaMA
Gene
staMA
SCLAV_p1114
Organism
Streptomyces clavuligerus ATCC 27064
1uniprot
The sequence of a 1.8 Mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010]
31
Q83WF7_9ACTO
(Q83WF7)
[query] 2 - 281 (283)
[subject] 1 - 280 (280)
1e-39 168   37%
Product
Methyltransferase
Gene
staMB
Organism
Streptomyces sp. TP-A0274
1uniprot
Direct formation of chromopyrrolic acid from indole-3-pyruvic acid by StaD, a novel hemoprotein in indolocarbazole biosynthesis.(Tetrahedron Lett.) [2006]
2uniprot
Biosynthesis of heterocyclic antibiotics in actinomycetes and an approach to synthesize the natural compounds.(Nihon Hosenkin Gakkaishi) [2006]
3uniprot[Pubmed] 12617516 [Medline] 22504382
Cloning of the staurosporine biosynthetic gene cluster from Streptomyces sp. TP-A0274 and its heterologous expression in Streptomyces lividans.(J. Antibiot.) [2002]
4uniprot
Characterization of the biosynthetic gene cluster of rebecamycin from Lechevalieria aerocolonigenes ATCC 39243.(Biosci. Biotechnol. Biochem.) [2003]
5uniprot[Pubmed] 16195595
Cytochrome P450 homolog is responsible for C-N bond formation between aglycone and deoxysugar in the staurosporine biosynthesis of Streptomyces sp. TP-A0274.(Biosci. Biotechnol. Biochem.) [2005]
[pubmed all]
32
Q9ALM7_9PSEU
(Q9ALM7)
Jump to Spino_00160
[query] 10 - 281 (283)
[subject] 7 - 273 (275)
3e-39 166   39%
Product
Methyltransferase-like protein
Gene
spnF
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 11358695 [Medline] 21257765
Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001]
33
Q4JHR3_9PSEU
(Q4JHR3)
[query] 10 - 281 (283)
[subject] 7 - 273 (275)
6e-39 165   37%
Product
BusF
Gene
busF
Organism
Saccharopolyspora pogona
1uniprot[Pubmed] 16179985
Butenyl-spinosyns, a natural example of genetic engineering of antibiotic biosynthetic genes.(J. Ind. Microbiol. Biotechnol.) [2006]
34
C6W8T2_ACTMD
(C6W8T2)
[query] 10 - 226 (283)
[subject] 9 - 230 (271)
7e-39 165   44%
Product
Methyltransferase type 11
Gene
Amir_3275
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
36
Q83WG2_9ACTO
(Q83WG2)
[query] 6 - 280 (283)
[subject] 3 - 275 (276)
5e-38 162   39%
Product
Methyltransferase
Gene
staMA
Organism
Streptomyces sp. TP-A0274
1uniprot
Direct formation of chromopyrrolic acid from indole-3-pyruvic acid by StaD, a novel hemoprotein in indolocarbazole biosynthesis.(Tetrahedron Lett.) [2006]
2uniprot
Biosynthesis of heterocyclic antibiotics in actinomycetes and an approach to synthesize the natural compounds.(Nihon Hosenkin Gakkaishi) [2006]
3uniprot[Pubmed] 12617516 [Medline] 22504382
Cloning of the staurosporine biosynthetic gene cluster from Streptomyces sp. TP-A0274 and its heterologous expression in Streptomyces lividans.(J. Antibiot.) [2002]
4uniprot
Characterization of the biosynthetic gene cluster of rebecamycin from Lechevalieria aerocolonigenes ATCC 39243.(Biosci. Biotechnol. Biochem.) [2003]
5uniprot[Pubmed] 16195595
Cytochrome P450 homolog is responsible for C-N bond formation between aglycone and deoxysugar in the staurosporine biosynthesis of Streptomyces sp. TP-A0274.(Biosci. Biotechnol. Biochem.) [2005]
[pubmed all]
38
Q9X5Q8_STRLA
(Q9X5Q8)
[query] 7 - 281 (283)
[subject] 3 - 274 (275)
1e-37 161   38%
Product
MitN
Gene
mitN
Organism
Streptomyces lavendulae
1uniprot[Pubmed] 10099135 [Medline] 99201491
Molecular characterization and analysis of the biosynthetic gene cluster for the antitumor antibiotic mitomycin C from Streptomyces lavendulae NRRL 2564.(Chem. Biol.) [1999]
39
B5GZG7_STRCL
(B5GZG7)
[query] 7 - 281 (283)
[subject] 9 - 283 (283)
6e-37 159   38%
Product
Methyltransferase
Gene
SCLAV_4762
SSCG_04741
Organism
Streptomyces clavuligerus ATCC 27064
1uniprot[Pubmed] 20624727
The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010]
40
D5SL02_STRCL
(D5SL02)
[query] 8 - 221 (283)
[subject] 8 - 223 (291)
1e-36 157   43%
Product
Staurosporine biosynthesis methyltransferase StaMB
Gene
staMB
SCLAV_p1109
Organism
Streptomyces clavuligerus ATCC 27064
1uniprot
The sequence of a 1.8 Mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010]
44
C6W8T1_ACTMD
(C6W8T1)
[query] 10 - 239 (283)
[subject] 3 - 234 (261)
2e-35 153   41%
Product
Methyltransferase type 11
Gene
Amir_3274
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
47
D5SKC5_STRCL
(D5SKC5)
[query] 14 - 281 (283)
[subject] 15 - 286 (291)
1e-32 144   34%
Product
Methyltransferase type 11
Gene
SCLAV_p0882
Organism
Streptomyces clavuligerus ATCC 27064
1uniprot
The sequence of a 1.8 Mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010]