BLAST table : Aver_00080

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accessionDBtoolalignmentEvalueScoreIdent.linkproductgeneorganismec
1
Q9S0R4_STRAW
(Q9S0R4)
[query] 1 - 5532 (5532)
[subject] 1 - 5532 (5532)
0.0 10930   100% Type I polyketide synthase AVES 3 aveA3
SAV942
SAV_942
Streptomyces avermitilis
2
A8J704_9ACTO
(A8J704)
[query] 1470 - 5528 (5532)
[subject] 1704 - 5672 (5674)
(5 hsp)
0.0 4496   64% Modular polyketide synthase nemA3 Streptomyces cyaneogriseus subsp. noncyanogenus
3
E0L044_STRVO
(E0L044)
[query] 38 - 5519 (5532)
[subject] 1854 - 7205 (7224)
(6 hsp)
0.0 4387   49% Beta-ketoacyl synthase StrviDRAFT_8272 Streptomyces violaceusniger Tu 4113
4
B3TMQ8_9ACTO
(B3TMQ8)
[query] 36 - 5529 (5532)
[subject] 1020 - 6240 (6241)
(5 hsp)
0.0 4373   50% Polyketide synthase KijS1 Actinomadura kijaniata
5
Q82QT4_STRAW
(Q82QT4)
[query] 38 - 5529 (5532)
[subject] 2552 - 7745 (7746)
(10 hsp)
0.0 4332   49% Modular polyketide synthase pteA1
SAV419
SAV_419
Streptomyces avermitilis
6
A4X8L0_SALTO
(A4X8L0)
[query] 36 - 5527 (5532)
[subject] 1909 - 7206 (7210)
(4 hsp)
0.0 4296   48% Beta-ketoacyl synthase Strop_2768 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
7
Q9ALM2_9PSEU
(Q9ALM2)
Jump to Spino_00210
[query] 4 - 5438 (5532)
[subject] 3 - 5290 (5588)
(4 hsp)
0.0 4286   48% Polyketide synthase extender modules 8-10 spnE Saccharopolyspora spinosa
8
B4VDY6_9ACTO
(B4VDY6)
[query] 30 - 5023 (5532)
[subject] 11 - 4851 (4894)
(2 hsp)
0.0 4252   51% Polyketide synthase type I SSAG_05828 Streptomyces sp. Mg1
9
Q52V52_9ACTO
(Q52V52)
[query] 3 - 5528 (5532)
[subject] 2 - 5430 (5432)
0.0 4251   48% Polyketide synthase type I Streptomyces aizunensis
10
F8QPF9_9ACTO
(F8QPF9)
[query] 1 - 5529 (5532)
[subject] 1 - 5338 (5339)
0.0 4236   48% Polyketide synthase natB Streptomyces sp. CS
11
D9T6W4_MICAI
(D9T6W4)
[query] 38 - 5438 (5532)
[subject] 1593 - 6819 (9936)
(13 hsp)
0.0 4221   49% Beta-ketoacyl synthase Micau_2464 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
12
E8S0C5_MICSL
(E8S0C5)
[query] 38 - 5438 (5532)
[subject] 1593 - 6819 (9937)
(14 hsp)
0.0 4216   49% Beta-ketoacyl synthase ML5_5898 Micromonospora sp. (strain L5)
13
B5L6K8_MICCH
(B5L6K8)
[query] 39 - 5528 (5532)
[subject] 1023 - 6303 (6305)
(6 hsp)
0.0 4205   48% Putative type I polyketide synthase Micromonospora chalcea
14
F1CLC1_9ACTO
(F1CLC1)
[query] 31 - 5529 (5532)
[subject] 1571 - 6830 (6831)
(6 hsp)
0.0 4179   48% ScnS1 scnS1 Streptomyces chattanoogensis
15
C6WNW1_ACTMD
(C6WNW1)
[query] 28 - 5527 (5532)
[subject] 1872 - 7106 (7110)
(4 hsp)
0.0 4177   49% Short-chain dehydrogenase/reductase SDR Amir_2695 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
16
D7BRD4_STRBB
(D7BRD4)
[query] 44 - 5529 (5532)
[subject] 4604 - 9949 (9950)
(7 hsp)
0.0 4164   48% Short-chain dehydrogenase/reductase SDR SBI_01976 Streptomyces bingchenggensis (strain BCW-1)
17
Q93NW6_9ACTO
(Q93NW6)
Jump to Amph_00170
[query] 38 - 5529 (5532)
[subject] 5575 - 10916 (10917)
(7 hsp)
0.0 4130   47% AmphC amphC Streptomyces nodosus
18
Q9X993_9ACTO
(Q9X993)
Jump to Pimar_00170
[query] 31 - 5529 (5532)
[subject] 1555 - 6796 (6797)
(6 hsp)
0.0 4116   48% PimS1 protein
Polyketide synthase
pimS1 Streptomyces natalensis
19
A1YAN0_AMYOR
(A1YAN0)
[query] 4 - 5529 (5532)
[subject] 3 - 5098 (5099)
0.0 4099   47% Polyketide synthase type I Amycolatopsis orientalis
Nocardia orientalis
20
D8HZ83_AMYMU
(D8HZ83)
[query] 1 - 5442 (5532)
[subject] 1 - 5009 (5060)
(2 hsp)
0.0 4065   48% Rifamycin polyketide synthase rifB
AMED_0618
Amycolatopsis mediterranei (strain U-32)
21
O52789_AMYMD
(O52789)
[query] 1 - 5442 (5532)
[subject] 10 - 5018 (5069)
(2 hsp)
0.0 4063   48% Rifamycin polyketide synthase, type 1 Amycolatopsis mediterranei
Nocardia mediterranei
22
O52545_AMYMD
(O52545)
Jump to Rifam_00220
[query] 1 - 5442 (5532)
[subject] 1 - 5009 (5060)
(2 hsp)
0.0 4063   48% RifB rifB Amycolatopsis mediterranei
Nocardia mediterranei
23
F8QPG0_9ACTO
(F8QPG0)
[query] 35 - 5528 (5532)
[subject] 28 - 5320 (5321)
0.0 4041   48% Polyketide synthase natC Streptomyces sp. CS
24
C3VLY1_9ACTO
(C3VLY1)
[query] 36 - 5529 (5532)
[subject] 1024 - 6382 (6383)
(7 hsp)
0.0 4018   45% Polyketide synthase type I mlaA1 Streptomyces sp. MP39-85
25
A8M6C7_SALAI
(A8M6C7)
[query] 1 - 5453 (5532)
[subject] 1 - 5192 (5255)
(2 hsp)
0.0 4017   48% Beta-ketoacyl synthase Sare_1247 Salinispora arenicola (strain CNS-205)
26
D6C477_9ACTO
(D6C477)
Jump to Meili_00310
[query] 1488 - 5527 (5532)
[subject] 1789 - 5819 (5822)
(6 hsp)
0.0 3989   57% Modular polyketide synthase meiA3 Streptomyces nanchangensis
27
Q6W5Q0_9ACTO
(Q6W5Q0)
Jump to FR008_00160
[query] 36 - 5441 (5532)
[subject] 1786 - 6948 (10625)
(7 hsp)
0.0 3982   48% FscC fscC Streptomyces sp. FR-008
28
D2CKM4_PSEAH
(D2CKM4)
[query] 31 - 5504 (5532)
[subject] 5577 - 10837 (10876)
(5 hsp)
0.0 3972   48% CppC cppC Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
29
Q54296_STRHY
(Q54296)
Jump to Rapam_00110
[query] 35 - 5528 (5532)
[subject] 5251 - 10219 (10223)
(4 hsp)
0.0 3968   46% Polyketide synthase rapB Streptomyces hygroscopicus
30
B5L6K9_MICCH
(B5L6K9)
[query] 31 - 5439 (5532)
[subject] 1732 - 6934 (7007)
(3 hsp)
0.0 3957   47% Putative type I polyketide synthase Micromonospora chalcea
31
Q6JHN7_9PSEU
(Q6JHN7)
[query] 1 - 5526 (5532)
[subject] 1 - 5176 (5176)
0.0 3900   46% ObsB Saccharopolyspora spinosa
32
C6WNV0_ACTMD
(C6WNV0)
[query] 4 - 5438 (5532)
[subject] 8 - 5110 (5400)
(2 hsp)
0.0 3852   47% Short-chain dehydrogenase/reductase SDR Amir_2684 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
33
C0SMW4_9ACTO
(C0SMW4)
Jump to Tauto_00110
[query] 31 - 5081 (5532)
[subject] 3795 - 8586 (10827)
(17 hsp)
0.0 3818   49% Type I modular polyketide synthase ttmJ Streptomyces spiroverticillatus
34
Q9L4W3_9ACTO
(Q9L4W3)
Jump to Nysta_00150
[query] 1 - 5069 (5532)
[subject] 1 - 4914 (11096)
(10 hsp)
0.0 3817   48% NysC nysC Streptomyces noursei
35
D9VEY7_9ACTO
(D9VEY7)
[query] 31 - 5438 (5532)
[subject] 119 - 5215 (5260)
(3 hsp)
0.0 3769   45% Modular polyketide synthase SSMG_05939 Streptomyces sp. AA4
36
D1XUK5_9ACTO
(D1XUK5)
[query] 3 - 5450 (5532)
[subject] 2 - 5088 (5157)
0.0 3761   46% Short-chain dehydrogenase/reductase SDR SACTEDRAFT_6365 Streptomyces sp. SA3_actE
37
D7F1M0_9ACTO
(D7F1M0)
[query] 3 - 4573 (5532)
[subject] 4 - 4401 (5136)
(6 hsp)
0.0 3745   49% Polyketide synthase tsnAII Streptomyces longisporoflavus
38
Q0PCZ9_STRHA
(Q0PCZ9)
Jump to Halsto_00060
[query] 4 - 4585 (5532)
[subject] 3 - 4516 (5232)
(6 hsp)
0.0 3731   49% Type I polyketide synthase hlsF Streptomyces halstedii
39
E8WEN5_STRFA
(E8WEN5)
[query] 3 - 5438 (5532)
[subject] 2 - 5075 (5156)
(2 hsp)
0.0 3725   46% Beta-ketoacyl synthase Sfla_0979 Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD)
40
B6ZIR3_STRPT
(B6ZIR3)
Jump to Pladi_00020
[query] 2 - 4569 (5532)
[subject] 5 - 4557 (7026)
(6 hsp)
0.0 3680   49% Polyketide synthase pldAII Streptomyces platensis
41
C6ZCS1_9ACTO
(C6ZCS1)
[query] 36 - 5067 (5532)
[subject] 4139 - 8783 (9528)
(12 hsp)
0.0 3675   47% Type I modular polyketide synthase ttnA Streptomyces griseochromogenes
42
A4KCE4_9ACTO
(A4KCE4)
Jump to Tatmc_00080
[query] 36 - 5067 (5532)
[subject] 4255 - 8903 (9648)
(11 hsp)
0.0 3665   47% Tautomycetin biosynthetic PKS Streptomyces sp. CK4412
43
B3TMQ7_9ACTO
(B3TMQ7)
[query] 5 - 5268 (5532)
[subject] 2 - 4958 (6872)
(5 hsp)
0.0 3634   46% Polyketide synthase KijS2 Actinomadura kijaniata
44
F8JUL0_STRCT
(F8JUL0)
[query] 38 - 4700 (5532)
[subject] 1030 - 5432 (5950)
(9 hsp)
0.0 3628   50% Putative polyketide synthase SCAT_3270 Streptomyces cattleya
45
B1W5P4_STRGG
(B1W5P4)
[query] 3 - 5524 (5532)
[subject] 2 - 4838 (4843)
0.0 3547   44% Putative type-I PKS pks3-2
SGR_6372
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
46
C3VLV4_9ACTO
(C3VLV4)
[query] 36 - 4701 (5532)
[subject] 1025 - 5576 (5582)
(6 hsp)
0.0 3536   46% Polyketide synthase type I becA Streptomyces sp. DSM 21069
47
D7P611_CHOCO
(D7P611)
[query] 514 - 5066 (5532)
[subject] 985 - 5462 (6255)
(10 hsp)
0.0 3501   47% TugA tugA Chondromyces crocatus
48
D9VBL5_9ACTO
(D9VBL5)
[query] 38 - 4325 (5532)
[subject] 982 - 4974 (5113)
(8 hsp)
0.0 3493   50% Modular polyketide synthase SSMG_01148 Streptomyces sp. AA4
49
Q54299_STRHY
(Q54299)
Jump to Rapam_00140
[query] 6 - 5066 (5532)
[subject] 5 - 4499 (6260)
(10 hsp)
0.0 3472   45% Polyketide synthase rapC Streptomyces hygroscopicus
50
F8JVX1_STRCT
(F8JVX1)
[query] 36 - 4571 (5532)
[subject] 1041 - 5405 (6125)
(9 hsp)
0.0 3469   47% Putative 6-methylsalicylic acid synthase SCAT_0136 Streptomyces cattleya 2.3.1.165

2.3.1.94
accessionDBtoolalignmentEvalueScoreIdent.linkinformationpubmed
1
Q9S0R4_STRAW
(Q9S0R4)
[query] 1 - 5532 (5532)
[subject] 1 - 5532 (5532)
0.0 10930   100%
Product
Type I polyketide synthase AVES 3
Gene
aveA3
SAV942
SAV_942
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 10449723 [Medline] 99380548
Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis.(Proc. Natl. Acad. Sci. U.S.A.) [1999]
2uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
3uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
4
B3TMQ8_9ACTO
(B3TMQ8)
[query] 36 - 5529 (5532)
[subject] 1020 - 6240 (6241)
(5 hsp)
0.0 4373   50%
Product
Polyketide synthase
Gene
KijS1
Organism
Actinomadura kijaniata
1uniprot[Pubmed] 17985890
Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
5
Q82QT4_STRAW
(Q82QT4)
[query] 38 - 5529 (5532)
[subject] 2552 - 7745 (7746)
(10 hsp)
0.0 4332   49%
Product
Modular polyketide synthase
Gene
pteA1
SAV419
SAV_419
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
7
Q9ALM2_9PSEU
(Q9ALM2)
Jump to Spino_00210
[query] 4 - 5438 (5532)
[subject] 3 - 5290 (5588)
(4 hsp)
0.0 4286   48%
Product
Polyketide synthase extender modules 8-10
Gene
spnE
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 11358695 [Medline] 21257765
Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001]
9
Q52V52_9ACTO
(Q52V52)
[query] 3 - 5528 (5532)
[subject] 2 - 5430 (5432)
0.0 4251   48%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
10
F8QPF9_9ACTO
(F8QPF9)
[query] 1 - 5529 (5532)
[subject] 1 - 5338 (5339)
0.0 4236   48%
Product
Polyketide synthase
Gene
natB
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
13
B5L6K8_MICCH
(B5L6K8)
[query] 39 - 5528 (5532)
[subject] 1023 - 6303 (6305)
(6 hsp)
0.0 4205   48%
Product
Putative type I polyketide synthase
Gene
 
Organism
Micromonospora chalcea
1uniprot[Pubmed] 18586939
Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
14
F1CLC1_9ACTO
(F1CLC1)
[query] 31 - 5529 (5532)
[subject] 1571 - 6830 (6831)
(6 hsp)
0.0 4179   48%
Product
ScnS1
Gene
scnS1
Organism
Streptomyces chattanoogensis
1uniprot[Pubmed] 21330439
The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011]
15
C6WNW1_ACTMD
(C6WNW1)
[query] 28 - 5527 (5532)
[subject] 1872 - 7106 (7110)
(4 hsp)
0.0 4177   49%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Amir_2695
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
16
D7BRD4_STRBB
(D7BRD4)
[query] 44 - 5529 (5532)
[subject] 4604 - 9949 (9950)
(7 hsp)
0.0 4164   48%
Product
Short-chain dehydrogenase/reductase SDR
Gene
SBI_01976
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
17
Q93NW6_9ACTO
(Q93NW6)
Jump to Amph_00170
[query] 38 - 5529 (5532)
[subject] 5575 - 10916 (10917)
(7 hsp)
0.0 4130   47%
Product
AmphC
Gene
amphC
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
[pubmed all]
18
Q9X993_9ACTO
(Q9X993)
Jump to Pimar_00170
[query] 31 - 5529 (5532)
[subject] 1555 - 6796 (6797)
(6 hsp)
0.0 4116   48%
Product
PimS1 protein
Polyketide synthase
Gene
pimS1
Organism
Streptomyces natalensis
1uniprot[Pubmed] 10187796 [Medline] 99214571
The biosynthetic gene cluster for the 26-membered ring polyene macrolide pimaricin. A new polyketide synthase organization encoded by two subclusters separated by functionalization genes.(J. Biol. Chem.) [1999]
2uniprot[Pubmed] 11094342 [Medline] 20547809
A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000]
[pubmed all]
19
A1YAN0_AMYOR
(A1YAN0)
[query] 4 - 5529 (5532)
[subject] 3 - 5098 (5099)
0.0 4099   47%
Product
Polyketide synthase type I
Gene
 
Organism
Amycolatopsis orientalis
Nocardia orientalis
1uniprot[Pubmed] 17136886
Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006]
20
D8HZ83_AMYMU
(D8HZ83)
[query] 1 - 5442 (5532)
[subject] 1 - 5009 (5060)
(2 hsp)
0.0 4065   48%
Product
Rifamycin polyketide synthase
Gene
rifB
AMED_0618
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
22
O52545_AMYMD
(O52545)
Jump to Rifam_00220
[query] 1 - 5442 (5532)
[subject] 1 - 5009 (5060)
(2 hsp)
0.0 4063   48%
Product
RifB
Gene
rifB
Organism
Amycolatopsis mediterranei
Nocardia mediterranei
1uniprot[Pubmed] 9512878 [Medline] 98174059
Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.(Chem. Biol.) [1998]
2uniprot[Pubmed] 9497318 [Medline] 98165773
3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.(J. Biol. Chem.) [1998]
3uniprot[Pubmed] 11278540 [Medline] 21201076
Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.(J. Biol. Chem.) [2001]
[pubmed all]
23
F8QPG0_9ACTO
(F8QPG0)
[query] 35 - 5528 (5532)
[subject] 28 - 5320 (5321)
0.0 4041   48%
Product
Polyketide synthase
Gene
natC
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
24
C3VLY1_9ACTO
(C3VLY1)
[query] 36 - 5529 (5532)
[subject] 1024 - 6382 (6383)
(7 hsp)
0.0 4018   45%
Product
Polyketide synthase type I
Gene
mlaA1
Organism
Streptomyces sp. MP39-85
1uniprot[Pubmed] 19854930
Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010]
26
D6C477_9ACTO
(D6C477)
Jump to Meili_00310
[query] 1488 - 5527 (5532)
[subject] 1789 - 5819 (5822)
(6 hsp)
0.0 3989   57%
Product
Modular polyketide synthase
Gene
meiA3
Organism
Streptomyces nanchangensis
1uniprot[Pubmed] 12811466 [Medline] 22777186
Identification of a gene cluster encoding meilingmycin biosynthesis among multiple polyketide synthase contigs isolated from Streptomyces nanchangensis NS3226.(Arch. Microbiol.) [2003]
2uniprot[Pubmed] 20348291
Cloning of separate meilingmycin biosynthesis gene clusters by use of acyltransferase-ketoreductase didomain PCR amplification.(Appl. Environ. Microbiol.) [2010]
[pubmed all]
27
Q6W5Q0_9ACTO
(Q6W5Q0)
Jump to FR008_00160
[query] 36 - 5441 (5532)
[subject] 1786 - 6948 (10625)
(7 hsp)
0.0 3982   48%
Product
FscC
Gene
fscC
Organism
Streptomyces sp. FR-008
1uniprot[Pubmed] 14652074
Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003]
28
D2CKM4_PSEAH
(D2CKM4)
[query] 31 - 5504 (5532)
[subject] 5577 - 10837 (10876)
(5 hsp)
0.0 3972   48%
Product
CppC
Gene
cppC
Organism
Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
1uniprot[Pubmed] 19697072
Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009]
29
Q54296_STRHY
(Q54296)
Jump to Rapam_00110
[query] 35 - 5528 (5532)
[subject] 5251 - 10219 (10223)
(4 hsp)
0.0 3968   46%
Product
Polyketide synthase
Gene
rapB
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]
30
B5L6K9_MICCH
(B5L6K9)
[query] 31 - 5439 (5532)
[subject] 1732 - 6934 (7007)
(3 hsp)
0.0 3957   47%
Product
Putative type I polyketide synthase
Gene
 
Organism
Micromonospora chalcea
1uniprot[Pubmed] 18586939
Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
31
Q6JHN7_9PSEU
(Q6JHN7)
[query] 1 - 5526 (5532)
[subject] 1 - 5176 (5176)
0.0 3900   46%
Product
ObsB
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
32
C6WNV0_ACTMD
(C6WNV0)
[query] 4 - 5438 (5532)
[subject] 8 - 5110 (5400)
(2 hsp)
0.0 3852   47%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Amir_2684
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
33
C0SMW4_9ACTO
(C0SMW4)
Jump to Tauto_00110
[query] 31 - 5081 (5532)
[subject] 3795 - 8586 (10827)
(17 hsp)
0.0 3818   49%
Product
Type I modular polyketide synthase
Gene
ttmJ
Organism
Streptomyces spiroverticillatus
1uniprot[Pubmed] 16707708
Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 18708355
Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008]
[pubmed all]
34
Q9L4W3_9ACTO
(Q9L4W3)
Jump to Nysta_00150
[query] 1 - 5069 (5532)
[subject] 1 - 4914 (11096)
(10 hsp)
0.0 3817   48%
Product
NysC
Gene
nysC
Organism
Streptomyces noursei
1uniprot[Pubmed] 10873841 [Medline] 20334850
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000]
40
B6ZIR3_STRPT
(B6ZIR3)
Jump to Pladi_00020
[query] 2 - 4569 (5532)
[subject] 5 - 4557 (7026)
(6 hsp)
0.0 3680   49%
Product
Polyketide synthase
Gene
pldAII
Organism
Streptomyces platensis
1uniprot[Pubmed] 18997414
Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008]
41
C6ZCS1_9ACTO
(C6ZCS1)
[query] 36 - 5067 (5532)
[subject] 4139 - 8783 (9528)
(12 hsp)
0.0 3675   47%
Product
Type I modular polyketide synthase
Gene
ttnA
Organism
Streptomyces griseochromogenes
1uniprot[Pubmed] 19191560
Characterization of the Tautomycetin Biosynthetic Gene Cluster from Streptomyces griseochromogenes Provides New Insight into Dialkylmaleic Anhydride Biosynthesis.(J. Nat. Prod.) [2009]
42
A4KCE4_9ACTO
(A4KCE4)
Jump to Tatmc_00080
[query] 36 - 5067 (5532)
[subject] 4255 - 8903 (9648)
(11 hsp)
0.0 3665   47%
Product
Tautomycetin biosynthetic PKS
Gene
 
Organism
Streptomyces sp. CK4412
1uniprot[Pubmed] 17379718
Isolation of the biosynthetic gene cluster for tautomycetin, a linear polyketide T cell-specific immunomodulator from Streptomyces sp. CK4412.(Microbiology) [2007]
43
B3TMQ7_9ACTO
(B3TMQ7)
[query] 5 - 5268 (5532)
[subject] 2 - 4958 (6872)
(5 hsp)
0.0 3634   46%
Product
Polyketide synthase
Gene
KijS2
Organism
Actinomadura kijaniata
1uniprot[Pubmed] 17985890
Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
45
B1W5P4_STRGG
(B1W5P4)
[query] 3 - 5524 (5532)
[subject] 2 - 4838 (4843)
0.0 3547   44%
Product
Putative type-I PKS
Gene
pks3-2
SGR_6372
Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]
46
C3VLV4_9ACTO
(C3VLV4)
[query] 36 - 4701 (5532)
[subject] 1025 - 5576 (5582)
(6 hsp)
0.0 3536   46%
Product
Polyketide synthase type I
Gene
becA
Organism
Streptomyces sp. DSM 21069
1uniprot[Pubmed] 19875084
Biosynthesis of macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit.(Chem. Biol.) [2009]
47
D7P611_CHOCO
(D7P611)
[query] 514 - 5066 (5532)
[subject] 985 - 5462 (6255)
(10 hsp)
0.0 3501   47%
Product
TugA
Gene
tugA
Organism
Chondromyces crocatus
1uniprot[Pubmed] 20416506
Biosynthesis of thuggacins in myxobacteria: comparative cluster analysis reveals basis for natural product structural diversity.(Chem. Biol.) [2010]
49
Q54299_STRHY
(Q54299)
Jump to Rapam_00140
[query] 6 - 5066 (5532)
[subject] 5 - 4499 (6260)
(10 hsp)
0.0 3472   45%
Product
Polyketide synthase
Gene
rapC
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]