BLAST table : Halsto_00040

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accessionDBtoolalignmentEvalueScoreIdent.linkproductgeneorganismec
1
 Q0PD01_STRHA
(Q0PD01)		 
[query] 1 - 5322 (5322)
[subject] 1 - 5322 (5322)
 0.0 10370   100% Type I polyketide synthase hlsD Streptomyces halstedii
2
 Q0PD00_STRHA
(Q0PD00)		 Jump to Halsto_00050 
[query] 11 - 3661 (5322)
[subject] 10 - 3710 (3809)
(4 hsp)		 0.0 5403   85% Type I polyketide synthase hlsE Streptomyces halstedii
3
 A0ACH1_STRAM
(A0ACH1)		 
[query] 27 - 5233 (5322)
[subject] 1541 - 6568 (8154)
(7 hsp)		 0.0 4539   53% Putative polyketide synthase B SAMR0465 Streptomyces ambofaciens ATCC 23877
4
 Q53840_SORCE
(Q53840)		 Jump to Soraph_00080 
[query] 32 - 5241 (5322)
[subject] 1588 - 6765 (8817)
(10 hsp)		 0.0 3895   46% Soraphen polyketide synthase B sorB Sorangium cellulosum
Polyangium cellulosum
5
 Q9L4X2_9ACTO
(Q9L4X2)		 Jump to Nysta_00060 
[query] 2 - 4576 (5322)
[subject] 9 - 4497 (5435)
(8 hsp)		 0.0 3796   51% NysJ nysJ Streptomyces noursei
6
 C0SMW3_9ACTO
(C0SMW3)		 Jump to Tauto_00100 
[query] 5 - 4593 (5322)
[subject] 6 - 4497 (5710)
(7 hsp)		 0.0 3769   51% Type I modular polyketide synthase ttmI Streptomyces spiroverticillatus
7
 D2CKL6_PSEAH
(D2CKL6)		 
[query] 11 - 4586 (5322)
[subject] 19 - 4493 (5425)
(6 hsp)		 0.0 3672   51% CppJ cppJ Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
8
 B6CLY8_9MYCO
(B6CLY8)		 
[query] 33 - 4577 (5322)
[subject] 7546 - 12112 (17019)
(35 hsp)		 0.0 3672   47% Type I modular polyketide synthase, MlsA1 mlsA1
MULP_065		 Mycobacterium liflandii 128FXT
9
 A0ACI3_STRAM
(A0ACI3)		 
[query] 1 - 4597 (5322)
[subject] 1 - 4534 (7024)
(10 hsp)		 0.0 3509   48% Putative type I modular polyketide synthase SAMR0477 Streptomyces ambofaciens ATCC 23877
10
 Q68BG5_STRHA
(Q68BG5)		 Jump to Halsto_00010 
[query] 2033 - 5287 (5322)
[subject] 911 - 4171 (4194)
(9 hsp)		 0.0 3446   59% Type I polyketide synthase hlsA Streptomyces halstedii
11
 Q52V46_9ACTO
(Q52V46)		 
[query] 1765 - 5233 (5322)
[subject] 4613 - 8068 (8147)
(11 hsp)		 0.0 3300   56% Polyketide synthase type I Streptomyces aizunensis
12
 B2HNF5_MYCMM
(B2HNF5)		 
[query] 1 - 4578 (5322)
[subject] 1 - 4538 (5495)
(7 hsp)		 0.0 3249   43% Type I modular polyketide synthase MMAR_3798 Mycobacterium marinum (strain ATCC BAA-535 / M)
13
 Q52V44_9ACTO
(Q52V44)		 
[query] 1767 - 5234 (5322)
[subject] 1442 - 4862 (6751)
(13 hsp)		 0.0 3187   55% Polyketide synthase type I Streptomyces aizunensis
14
 B5M9K9_9ACTO
(B5M9K9)		 
[query] 8 - 3669 (5322)
[subject] 1764 - 5378 (5469)
(8 hsp)		 0.0 3182   51% Lasalocid modular polyketide synthase lasAII Streptomyces lasaliensis
15
 B6ZK65_9ACTO
(B6ZK65)		 Jump to Lasal_00140 
[query] 8 - 3669 (5322)
[subject] 1724 - 5338 (5429)
(8 hsp)		 0.0 3181   51% Putative polyketide synthase lsd12 Streptomyces lasaliensis
16
 Q93H84_STRAW
(Q93H84)		 
[query] 1744 - 5231 (5322)
[subject] 2657 - 6062 (6145)
(8 hsp)		 0.0 3164   54% Modular polyketide synthase pteA4
SAV416
SAV_416		 Streptomyces avermitilis
17
 Q1WEK7_9ACTO
(Q1WEK7)		 
[query] 1745 - 5233 (5322)
[subject] 4086 - 7380 (7968)
(11 hsp)		 0.0 3076   54% Polyketide synthase merC Streptomyces sp. NRRL 30748
18
 B4VBW0_9ACTO
(B4VBW0)		 
[query] 2036 - 5234 (5322)
[subject] 74 - 3235 (10873)
(18 hsp)		 0.0 3026   55% Polyketide synthase type I SSAG_05337 Streptomyces sp. Mg1
19
 Q68BG4_STRHA
(Q68BG4)		 Jump to Halsto_00020 
[query] 2142 - 4581 (5322)
[subject] 34 - 2464 (7111)
(11 hsp)		 0.0 3019   67% Type I polyketide synthase hlsB Streptomyces halstedii
20
 Q27W58_STRVO
(Q27W58)		 Jump to Niger_00170 
[query] 1781 - 5232 (5322)
[subject] 1240 - 4701 (4787)
(6 hsp)		 0.0 3000   49% NigAVII Streptomyces violaceoniger
21
 B5M9L2_9ACTO
(B5M9L2)		 Jump to Lasal_00170 
[query] 2 - 3664 (5322)
[subject] 3 - 3588 (3679)
(4 hsp)		 0.0 2982   49% Lasalocid modular polyketide synthase
Putative polyketide synthase		 lasAV
lsd15		 Streptomyces lasaliensis
22
 Q1L0T2_STRHY
(Q1L0T2)		 
[query] 28 - 3661 (5322)
[subject] 3177 - 6766 (6855)
(9 hsp)		 0.0 2972   49% GelA Streptomyces hygroscopicus subsp. duamyceticus
23
 Q84G24_STRHY
(Q84G24)		 
[query] 28 - 3661 (5322)
[subject] 3164 - 6753 (6842)
(9 hsp)		 0.0 2967   49% GdmAI gdmAI Streptomyces hygroscopicus
24
 Q49BE1_STRHY
(Q49BE1)		 Jump to Herb_00170 
[query] 28 - 3661 (5322)
[subject] 3153 - 6731 (6820)
(9 hsp)		 0.0 2966   49% HbmAI hbmAI Streptomyces hygroscopicus
25
 A0FCL3_STRVO
(A0FCL3)		 Jump to Merid_00040 
[query] 1745 - 5233 (5322)
[subject] 4089 - 7405 (11604)
(17 hsp)		 0.0 2957   52% MerC merC Streptomyces violaceoniger
26
 C0SMW4_9ACTO
(C0SMW4)		 Jump to Tauto_00110 
[query] 28 - 3661 (5322)
[subject] 7193 - 10779 (10827)
(22 hsp)		 0.0 2947   50% Type I modular polyketide synthase ttmJ Streptomyces spiroverticillatus
27
 Q9L4X3_9ACTO
(Q9L4X3)		 Jump to Nysta_00050 
[query] 1781 - 5231 (5322)
[subject] 1458 - 4879 (9477)
(13 hsp)		 0.0 2939   51% NysI nysI Streptomyces noursei
28
 Q93NX9_9ACTO
(Q93NX9)		 Jump to Amph_00040 
[query] 1741 - 5231 (5322)
[subject] 1377 - 4834 (9510)
(14 hsp)		 0.0 2937   51% AmphI amphI Streptomyces nodosus
29
 Q9ALM3_9PSEU
(Q9ALM3)		 Jump to Spino_00200 
[query] 1766 - 5232 (5322)
[subject] 1421 - 4848 (4928)
(7 hsp)		 0.0 2932   52% Polyketide synthase extender modules 5-7 spnD Saccharopolyspora spinosa
30
 Q6MZ72_MYCUA
(Q6MZ72)		 Jump to MUP_00320 
[query] 1766 - 5233 (5322)
[subject] 1444 - 4877 (14130)
(34 hsp)		 0.0 2911   49% Type I modular polyketide synthase mlsB
MUP032c		 Mycobacterium ulcerans (strain Agy99)
31
 Q6W5P7_9ACTO
(Q6W5P7)		 Jump to FR008_00190 
[query] 1323 - 4576 (5322)
[subject] 3322 - 6507 (7771)
(11 hsp)		 0.0 2909   54% FscE fscE Streptomyces sp. FR-008
32
 B6CLY1_9MYCO
(B6CLY1)		 
[query] 1766 - 5233 (5322)
[subject] 1436 - 4872 (12352)
(25 hsp)		 0.0 2896   49% Type I modular polyketide synthase, MlsB mlsB
MULP_051		 Mycobacterium liflandii 128FXT
33
 D2CKL5_PSEAH
(D2CKL5)		 
[query] 1781 - 5235 (5322)
[subject] 1438 - 4866 (9499)
(13 hsp)		 0.0 2860   51% CppI cppI Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
34
 Q9EWA1_9ACTO
(Q9EWA1)		 Jump to Pimar_00070 
[query] 1781 - 5233 (5322)
[subject] 4502 - 7879 (9507)
(15 hsp)		 0.0 2854   49% PimS2 protein pimS2 Streptomyces natalensis
35
 A0ACH2_STRAM
(A0ACH2)		 
[query] 1 - 3664 (5322)
[subject] 1 - 3575 (3661)
(3 hsp)		 0.0 2840   49% Putative polyketide synthase B SAMR0466 Streptomyces ambofaciens ATCC 23877
36
 Q6W5P6_9ACTO
(Q6W5P6)		 Jump to FR008_00200 
[query] 1761 - 5240 (5322)
[subject] 4493 - 7918 (9550)
(14 hsp)		 0.0 2839   50% FscD fscD Streptomyces sp. FR-008
37
 Q52V50_9ACTO
(Q52V50)		 
[query] 28 - 3024 (5322)
[subject] 1828 - 4806 (7510)
(17 hsp)		 0.0 2820   55% Polyketide synthase type I Streptomyces aizunensis
38
 D3C7A9_9ACTO
(D3C7A9)		 
[query] 1764 - 5231 (5322)
[subject] 6463 - 9849 (9937)
(17 hsp)		 0.0 2798   51% Mycocerosate synthase, 6-deoxyerythronolide-B synthase ML5DRAFT_1446 Micromonospora sp. L5 2.3.1.111

2.3.1.94
39
 Q76KY0_STRHA
(Q76KY0)		 Jump to Vicen_00200 
[query] 33 - 3027 (5322)
[subject] 136 - 3096 (5826)
(14 hsp)		 0.0 2776   54% Polyketide synthase modules 1-3 vinP1 Streptomyces halstedii
40
 C0Z475_STRVN
(C0Z475)		 
[query] 22 - 3039 (5322)
[subject] 23 - 3020 (3447)
(7 hsp)		 0.0 2764   54% Type I polyketide synthase, modules 7-8 ken14 Streptomyces violaceoruber
41
 D1SGG3_9ACTO
(D1SGG3)		 
[query] 28 - 3024 (5322)
[subject] 2095 - 5055 (7520)
(12 hsp)		 0.0 2764   54% KR domain protein MicauDRAFT_5307 Micromonospora aurantiaca ATCC 27029
42
 C6W8V1_ACTMD
(C6W8V1)		 
[query] 33 - 3662 (5322)
[subject] 3153 - 6669 (6768)
(9 hsp)		 0.0 2760   49% Acyl transferase Amir_3294 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
43
 D3C7A8_9ACTO
(D3C7A8)		 
[query] 28 - 3024 (5322)
[subject] 2095 - 5055 (7520)
(12 hsp)		 0.0 2748   54% KR domain protein ML5DRAFT_1445 Micromonospora sp. L5
44
 B5A9P9_9PSEU
(B5A9P9)		 
[query] 33 - 3662 (5322)
[subject] 3160 - 6676 (6775)
(9 hsp)		 0.0 2748   49% MbcAI mbcAI Actinosynnema pretiosum subsp. pretiosum
45
 A4FDM8_SACEN
(A4FDM8)		 
[query] 34 - 3028 (5322)
[subject] 1068 - 4017 (4132)
(9 hsp)		 0.0 2748   54% Modular polyketide synthase- SACE_2875 Saccharopolyspora erythraea (strain NRRL 23338)
46
 A4F5C6_SORCE
(A4F5C6)		 
[query] 34 - 3674 (5322)
[subject] 1601 - 5250 (5331)
(7 hsp)		 0.0 2748   47% Polyketide synthase spiG Sorangium cellulosum
Polyangium cellulosum
47
 Q93HJ3_STRAW
(Q93HJ3)		 Jump to Oligo_00100 
[query] 1 - 3037 (5322)
[subject] 1 - 2993 (3939)
(8 hsp)		 0.0 2739   52% Modular polyketide synthase olmA3
SAV2897
SAV_2897		 Streptomyces avermitilis
48
 Q0PD02_STRHA
(Q0PD02)		 Jump to Halsto_00030 
[query] 2140 - 4592 (5322)
[subject] 32 - 2485 (5220)
(12 hsp)		 0.0 2739   62% Type I polyketide synthase hlsC Streptomyces halstedii
49
 Q93NW6_9ACTO
(Q93NW6)		 Jump to Amph_00170 
[query] 9 - 3020 (5322)
[subject] 3476 - 6451 (10917)
(25 hsp)		 0.0 2735   54% AmphC amphC Streptomyces nodosus
50
 D1GLV9_9ACTO
(D1GLV9)		 Jump to Strply_00310 
[query] 2061 - 5242 (5322)
[subject] 974 - 4176 (6171)
(13 hsp)		 0.0 2734   52% Polyketide synthase type I slgA1 Streptomyces lydicus
accessionDBtoolalignmentEvalueScoreIdent.linkinformationpubmed
3
 A0ACH1_STRAM
(A0ACH1)		 
[query] 27 - 5233 (5322)
[subject] 1541 - 6568 (8154)
(7 hsp)		 0.0 4539   53%
Product
Putative polyketide synthase B
Gene
SAMR0465
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
2uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
4
 Q53840_SORCE
(Q53840)		 Jump to Soraph_00080 
[query] 32 - 5241 (5322)
[subject] 1588 - 6765 (8817)
(10 hsp)		 0.0 3895   46%
Product
Soraphen polyketide synthase B
Gene
sorB
Organism
Sorangium cellulosum
Polyangium cellulosum
1uniprot[Pubmed] 7601830 [Medline] 95325306
A Sorangium cellulosum (myxobacterium) gene cluster for the biosynthesis of the macrolide antibiotic soraphen A: cloning, characterization, and homology to polyketide synthase genes from actinomycetes.(J. Bacteriol.) [1995]
2uniprot[Pubmed] 12039053 [Medline] 22035375
Characterization of the biosynthetic gene cluster for the antifungal polyketide soraphen A from Sorangium cellulosum So ce26.(Gene) [2002]
[pubmed all]
5
 Q9L4X2_9ACTO
(Q9L4X2)		 Jump to Nysta_00060 
[query] 2 - 4576 (5322)
[subject] 9 - 4497 (5435)
(8 hsp)		 0.0 3796   51%
Product
NysJ
Gene
nysJ
Organism
Streptomyces noursei
1uniprot[Pubmed] 10873841 [Medline] 20334850
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000]
6
 C0SMW3_9ACTO
(C0SMW3)		 Jump to Tauto_00100 
[query] 5 - 4593 (5322)
[subject] 6 - 4497 (5710)
(7 hsp)		 0.0 3769   51%
Product
Type I modular polyketide synthase
Gene
ttmI
Organism
Streptomyces spiroverticillatus
1uniprot[Pubmed] 16707708
Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 18708355
Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008]
[pubmed all]
7
 D2CKL6_PSEAH
(D2CKL6)		 
[query] 11 - 4586 (5322)
[subject] 19 - 4493 (5425)
(6 hsp)		 0.0 3672   51%
Product
CppJ
Gene
cppJ
Organism
Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
1uniprot[Pubmed] 19697072
Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009]
8
 B6CLY8_9MYCO
(B6CLY8)		 
[query] 33 - 4577 (5322)
[subject] 7546 - 12112 (17019)
(35 hsp)		 0.0 3672   47%
Product
Type I modular polyketide synthase, MlsA1
Gene
mlsA1
MULP_065
Organism
Mycobacterium liflandii 128FXT
1uniprot[Pubmed] 18840298
Deciphering the genetic basis for polyketide variation among mycobacteria producing mycolactones.(BMC Genomics) [2008]
9
 A0ACI3_STRAM
(A0ACI3)		 
[query] 1 - 4597 (5322)
[subject] 1 - 4534 (7024)
(10 hsp)		 0.0 3509   48%
Product
Putative type I modular polyketide synthase
Gene
SAMR0477
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
2uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
10
 Q68BG5_STRHA
(Q68BG5)		 Jump to Halsto_00010 
[query] 2033 - 5287 (5322)
[subject] 911 - 4171 (4194)
(9 hsp)		 0.0 3446   59%
Product
Type I polyketide synthase
Gene
hlsA
Organism
Streptomyces halstedii
1uniprot
Genome-inspired search for new antibiotics; Isolation and structure determination of new 28-membered polyketide macrolactones, halstoctacosanolides A and B, from Streptomyces halstedii HC34.(Tetrahedron) [2004]
11
 Q52V46_9ACTO
(Q52V46)		 
[query] 1765 - 5233 (5322)
[subject] 4613 - 8068 (8147)
(11 hsp)		 0.0 3300   56%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
12
 B2HNF5_MYCMM
(B2HNF5)		 
[query] 1 - 4578 (5322)
[subject] 1 - 4538 (5495)
(7 hsp)		 0.0 3249   43%
Product
Type I modular polyketide synthase
Gene
MMAR_3798
Organism
Mycobacterium marinum (strain ATCC BAA-535 / M)
1uniprot[Pubmed] 18403782
Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis.(Genome Res.) [2008]
13
 Q52V44_9ACTO
(Q52V44)		 
[query] 1767 - 5234 (5322)
[subject] 1442 - 4862 (6751)
(13 hsp)		 0.0 3187   55%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
15
 B6ZK65_9ACTO
(B6ZK65)		 Jump to Lasal_00140 
[query] 8 - 3669 (5322)
[subject] 1724 - 5338 (5429)
(8 hsp)		 0.0 3181   51%
Product
Putative polyketide synthase
Gene
lsd12
Organism
Streptomyces lasaliensis
1uniprot[Pubmed] 19129623
Identification of a gene cluster of polyether antibiotic lasalocid from Streptomyces lasaliensis.(Biosci. Biotechnol. Biochem.) [2009]
2uniprot[Pubmed] 18710235
Epoxide hydrolase Lsd19 for polyether formation in the biosynthesis of lasalocid A: direct experimental evidence on polyene-polyepoxide hypothesis in polyether biosynthesis.(J. Am. Chem. Soc.) [2008]
[pubmed all]
16
 Q93H84_STRAW
(Q93H84)		 
[query] 1744 - 5231 (5322)
[subject] 2657 - 6062 (6145)
(8 hsp)		 0.0 3164   54%
Product
Modular polyketide synthase
Gene
pteA4
SAV416
SAV_416
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
2uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
17
 Q1WEK7_9ACTO
(Q1WEK7)		 
[query] 1745 - 5233 (5322)
[subject] 4086 - 7380 (7968)
(11 hsp)		 0.0 3076   54%
Product
Polyketide synthase
Gene
merC
Organism
Streptomyces sp. NRRL 30748
1uniprot[Pubmed] 16806745
Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006]
19
 Q68BG4_STRHA
(Q68BG4)		 Jump to Halsto_00020 
[query] 2142 - 4581 (5322)
[subject] 34 - 2464 (7111)
(11 hsp)		 0.0 3019   67%
Product
Type I polyketide synthase
Gene
hlsB
Organism
Streptomyces halstedii
1uniprot
Genome-inspired search for new antibiotics; Isolation and structure determination of new 28-membered polyketide macrolactones, halstoctacosanolides A and B, from Streptomyces halstedii HC34.(Tetrahedron) [2004]
20
 Q27W58_STRVO
(Q27W58)		 Jump to Niger_00170 
[query] 1781 - 5232 (5322)
[subject] 1240 - 4701 (4787)
(6 hsp)		 0.0 3000   49%
Product
NigAVII
Gene
 
Organism
Streptomyces violaceoniger
1uniprot[Pubmed] 17584617
Insights into Polyether Biosynthesis from Analysis of the Nigericin Biosynthetic Gene Cluster in Streptomyces sp. DSM4137.(Chem. Biol.) [2007]
21
 B5M9L2_9ACTO
(B5M9L2)		 Jump to Lasal_00170 
[query] 2 - 3664 (5322)
[subject] 3 - 3588 (3679)
(4 hsp)		 0.0 2982   49%
Product
Lasalocid modular polyketide synthase
Putative polyketide synthase
Gene
lasAV
lsd15
Organism
Streptomyces lasaliensis
1uniprot[Pubmed] 19129623
Identification of a gene cluster of polyether antibiotic lasalocid from Streptomyces lasaliensis.(Biosci. Biotechnol. Biochem.) [2009]
2uniprot[Pubmed] 18710235
Epoxide hydrolase Lsd19 for polyether formation in the biosynthesis of lasalocid A: direct experimental evidence on polyene-polyepoxide hypothesis in polyether biosynthesis.(J. Am. Chem. Soc.) [2008]
[pubmed all]
22
 Q1L0T2_STRHY
(Q1L0T2)		 
[query] 28 - 3661 (5322)
[subject] 3177 - 6766 (6855)
(9 hsp)		 0.0 2972   49%
Product
GelA
Gene
 
Organism
Streptomyces hygroscopicus subsp. duamyceticus
1uniprot[Pubmed] 18600054
Characterization of tailoring genes involved in the modification of geldanamycin polyketide in Streptomyces hygroscopicus JCM4427.(J. Microbiol. Biotechnol.) [2008]
23
 Q84G24_STRHY
(Q84G24)		 
[query] 28 - 3661 (5322)
[subject] 3164 - 6753 (6842)
(9 hsp)		 0.0 2967   49%
Product
GdmAI
Gene
gdmAI
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 12586396 [Medline] 22474162
Cloning and characterization of a gene cluster for geldanamycin production in Streptomyces hygroscopicus NRRL 3602.(FEMS Microbiol. Lett.) [2003]
24
 Q49BE1_STRHY
(Q49BE1)		 Jump to Herb_00170 
[query] 28 - 3661 (5322)
[subject] 3153 - 6731 (6820)
(9 hsp)		 0.0 2966   49%
Product
HbmAI
Gene
hbmAI
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 16085885
Insights into the biosynthesis of the benzoquinone ansamycins geldanamycin and herbimycin, obtained by gene sequencing and disruption.(Appl. Environ. Microbiol.) [2005]
25
 A0FCL3_STRVO
(A0FCL3)		 Jump to Merid_00040 
[query] 1745 - 5233 (5322)
[subject] 4089 - 7405 (11604)
(17 hsp)		 0.0 2957   52%
Product
MerC
Gene
merC
Organism
Streptomyces violaceoniger
1uniprot[Pubmed] 17159202
Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006]
26
 C0SMW4_9ACTO
(C0SMW4)		 Jump to Tauto_00110 
[query] 28 - 3661 (5322)
[subject] 7193 - 10779 (10827)
(22 hsp)		 0.0 2947   50%
Product
Type I modular polyketide synthase
Gene
ttmJ
Organism
Streptomyces spiroverticillatus
1uniprot[Pubmed] 16707708
Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 18708355
Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008]
[pubmed all]
27
 Q9L4X3_9ACTO
(Q9L4X3)		 Jump to Nysta_00050 
[query] 1781 - 5231 (5322)
[subject] 1458 - 4879 (9477)
(13 hsp)		 0.0 2939   51%
Product
NysI
Gene
nysI
Organism
Streptomyces noursei
1uniprot[Pubmed] 10873841 [Medline] 20334850
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000]
28
 Q93NX9_9ACTO
(Q93NX9)		 Jump to Amph_00040 
[query] 1741 - 5231 (5322)
[subject] 1377 - 4834 (9510)
(14 hsp)		 0.0 2937   51%
Product
AmphI
Gene
amphI
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
[pubmed all]
29
 Q9ALM3_9PSEU
(Q9ALM3)		 Jump to Spino_00200 
[query] 1766 - 5232 (5322)
[subject] 1421 - 4848 (4928)
(7 hsp)		 0.0 2932   52%
Product
Polyketide synthase extender modules 5-7
Gene
spnD
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 11358695 [Medline] 21257765
Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001]
30
 Q6MZ72_MYCUA
(Q6MZ72)		 Jump to MUP_00320 
[query] 1766 - 5233 (5322)
[subject] 1444 - 4877 (14130)
(34 hsp)		 0.0 2911   49%
Product
Type I modular polyketide synthase
Gene
mlsB
MUP032c
Organism
Mycobacterium ulcerans (strain Agy99)
1uniprot[Pubmed] 14736915
Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans.(Proc. Natl. Acad. Sci. U.S.A.) [2004]
2uniprot[Pubmed] 15758215
Functional analysis and annotation of the virulence plasmid pMUM001 from Mycobacterium ulcerans.(Microbiology) [2005]
[pubmed all]
31
 Q6W5P7_9ACTO
(Q6W5P7)		 Jump to FR008_00190 
[query] 1323 - 4576 (5322)
[subject] 3322 - 6507 (7771)
(11 hsp)		 0.0 2909   54%
Product
FscE
Gene
fscE
Organism
Streptomyces sp. FR-008
1uniprot[Pubmed] 14652074
Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003]
32
 B6CLY1_9MYCO
(B6CLY1)		 
[query] 1766 - 5233 (5322)
[subject] 1436 - 4872 (12352)
(25 hsp)		 0.0 2896   49%
Product
Type I modular polyketide synthase, MlsB
Gene
mlsB
MULP_051
Organism
Mycobacterium liflandii 128FXT
1uniprot[Pubmed] 18840298
Deciphering the genetic basis for polyketide variation among mycobacteria producing mycolactones.(BMC Genomics) [2008]
33
 D2CKL5_PSEAH
(D2CKL5)		 
[query] 1781 - 5235 (5322)
[subject] 1438 - 4866 (9499)
(13 hsp)		 0.0 2860   51%
Product
CppI
Gene
cppI
Organism
Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
1uniprot[Pubmed] 19697072
Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009]
34
 Q9EWA1_9ACTO
(Q9EWA1)		 Jump to Pimar_00070 
[query] 1781 - 5233 (5322)
[subject] 4502 - 7879 (9507)
(15 hsp)		 0.0 2854   49%
Product
PimS2 protein
Gene
pimS2
Organism
Streptomyces natalensis
1uniprot[Pubmed] 11094342 [Medline] 20547809
A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000]
35
 A0ACH2_STRAM
(A0ACH2)		 
[query] 1 - 3664 (5322)
[subject] 1 - 3575 (3661)
(3 hsp)		 0.0 2840   49%
Product
Putative polyketide synthase B
Gene
SAMR0466
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
2uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
36
 Q6W5P6_9ACTO
(Q6W5P6)		 Jump to FR008_00200 
[query] 1761 - 5240 (5322)
[subject] 4493 - 7918 (9550)
(14 hsp)		 0.0 2839   50%
Product
FscD
Gene
fscD
Organism
Streptomyces sp. FR-008
1uniprot[Pubmed] 14652074
Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003]
37
 Q52V50_9ACTO
(Q52V50)		 
[query] 28 - 3024 (5322)
[subject] 1828 - 4806 (7510)
(17 hsp)		 0.0 2820   55%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
39
 Q76KY0_STRHA
(Q76KY0)		 Jump to Vicen_00200 
[query] 33 - 3027 (5322)
[subject] 136 - 3096 (5826)
(14 hsp)		 0.0 2776   54%
Product
Polyketide synthase modules 1-3
Gene
vinP1
Organism
Streptomyces halstedii
1uniprot[Pubmed] 15112997
Cloning, sequencing, and functional analysis of the biosynthetic gene cluster of macrolactam antibiotic vicenistatin in Streptomyces halstedii.(Chem. Biol.) [2004]
42
 C6W8V1_ACTMD
(C6W8V1)		 
[query] 33 - 3662 (5322)
[subject] 3153 - 6669 (6768)
(9 hsp)		 0.0 2760   49%
Product
Acyl transferase
Gene
Amir_3294
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101T).(Stand. Genomic Sci.) [2009]
45
 A4FDM8_SACEN
(A4FDM8)		 
[query] 34 - 3028 (5322)
[subject] 1068 - 4017 (4132)
(9 hsp)		 0.0 2748   54%
Product
Modular polyketide synthase-
Gene
SACE_2875
Organism
Saccharopolyspora erythraea (strain NRRL 23338)
1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
46
 A4F5C6_SORCE
(A4F5C6)		 
[query] 34 - 3674 (5322)
[subject] 1601 - 5250 (5331)
(7 hsp)		 0.0 2748   47%
Product
Polyketide synthase
Gene
spiG
Organism
Sorangium cellulosum
Polyangium cellulosum
1uniprot[Pubmed] 17317575
Spiroketal polyketide formation in Sorangium: Identification of the biosynthetic gene cluster for the highly cytotoxic spirangienes.(Chem. Biol.) [2007]
47
 Q93HJ3_STRAW
(Q93HJ3)		 Jump to Oligo_00100 
[query] 1 - 3037 (5322)
[subject] 1 - 2993 (3939)
(8 hsp)		 0.0 2739   52%
Product
Modular polyketide synthase
Gene
olmA3
SAV2897
SAV_2897
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
2uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
49
 Q93NW6_9ACTO
(Q93NW6)		 Jump to Amph_00170 
[query] 9 - 3020 (5322)
[subject] 3476 - 6451 (10917)
(25 hsp)		 0.0 2735   54%
Product
AmphC
Gene
amphC
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
[pubmed all]
50
 D1GLV9_9ACTO
(D1GLV9)		 Jump to Strply_00310 
[query] 2061 - 5242 (5322)
[subject] 974 - 4176 (6171)
(13 hsp)		 0.0 2734   52%
Product
Polyketide synthase type I
Gene
slgA1
Organism
Streptomyces lydicus
1uniprot
Deciphering biosynthesis of the RNA polymerase inhibitor streptolydigin and generation of glycosylated derivatives.(Chem. Biol.) [2009]
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