BLAST table : Medem_00150

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accessionDBtoolalignmentEvalueScoreIdent.linkproductgeneorganismec
1
Q7WT27_9ACTO
(Q7WT27)
[query] 1 - 318 (318)
[subject] 1 - 318 (318)
0.0 642   100% First ring aromatase (ARO) med-ORF19 Streptomyces sp. AM-7161
2
Q2HR24_9ACTO
(Q2HR24)
Jump to Sch475_00340
[query] 5 - 318 (318)
[subject] 2 - 312 (312)
1e-107 391   61% Putative aromatase schP4 Streptomyces sp. SCC 2136
3
C4NYK3_9ACTO
(C4NYK3)
[query] 1 - 314 (318)
[subject] 1 - 310 (314)
1e-100 368   59% SaqL saqL Micromonospora sp. Tu 6368
4
Q54221_STRGR
(Q54221)
Jump to Griseu_00050
[query] 1 - 317 (318)
[subject] 1 - 313 (319)
2e-99 366   58% Putative cyclase/dehydrase Streptomyces griseus
5
Q6ZZV8_STRAT
(Q6ZZV8)
Jump to Ovied_00150
[query] 5 - 318 (318)
[subject] 2 - 311 (315)
6e-97 358   57% Aromatase ovmA Streptomyces antibioticus
6
Q9AMI9_STRAT
(Q9AMI9)
[query] 11 - 317 (318)
[subject] 11 - 314 (315)
1e-96 357   57% Putative cyclase/dehydrase SimA5
Sim6
simA5
sim6
Streptomyces antibioticus
7
Q47QK9_THEFY
(Q47QK9)
[query] 3 - 318 (318)
[subject] 2 - 314 (314)
2e-96 356   58% Actinorhodin polyketide synthase bifunctional cyclase/dehydratase Tfu_1222 Thermobifida fusca (strain YX)
8
D2XDY3_9PSEU
(D2XDY3)
[query] 1 - 317 (318)
[subject] 1 - 315 (316)
2e-95 352   55% AzicE azicE Kibdelosporangium sp. MJ126-NF4
9
D1XRF3_9ACTO
(D1XRF3)
[query] 1 - 318 (318)
[subject] 1 - 314 (314)
3e-95 352   56% Cyclase/dehydrase SACTEDRAFT_5263 Streptomyces sp. ACTE
10
Q93M00_STRAU
(Q93M00)
[query] 1 - 317 (318)
[subject] 1 - 313 (316)
3e-95 352   56% Cyclase/dehydratase-like protein aur2F Streptomyces aureofaciens
11
Q56H98_STRAU
(Q56H98)
[query] 1 - 314 (318)
[subject] 1 - 310 (320)
5e-95 351   57% Aur1H aur1H Streptomyces aureofaciens
12
Q84CH8_9ACTO
(Q84CH8)
[query] 1 - 318 (318)
[subject] 1 - 314 (314)
2e-94 349   55% Cyclase-like protein pd2D Streptomyces sp. WP 4669
13
Q93LY0_9ACTO
(Q93LY0)
[query] 1 - 317 (318)
[subject] 1 - 313 (314)
8e-94 347   56% Putative bifunctional aromatase PgaL pgaL Streptomyces sp. PGA64
14
C7QAF6_CATAD
(C7QAF6)
[query] 1 - 318 (318)
[subject] 1 - 315 (316)
2e-93 346   54% Cyclase/dehydrase Caci_3550 Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
15
Q9RPB1_STRFR
(Q9RPB1)
Jump to Urd_00160
[query] 5 - 318 (318)
[subject] 2 - 311 (311)
2e-92 343   55% Cyclase urdL Streptomyces fradiae
16
B5HT04_9ACTO
(B5HT04)
[query] 10 - 318 (318)
[subject] 2 - 306 (306)
2e-91 339   56% Cyclase SSEG_02721 Streptomyces sviceus ATCC 29083
17
Q2J5F1_FRASC
(Q2J5F1)
[query] 2 - 318 (318)
[subject] 5 - 318 (318)
4e-90 335   54% Actinorhodin polyketide synthase bifunctional cyclase/dehydratase Francci3_4143 Frankia sp. (strain CcI3)
18
Q9ZGD3_STRCY
(Q9ZGD3)
Jump to Lando_00070
[query] 5 - 318 (318)
[subject] 2 - 318 (319)
8e-89 331   54% Cyclase homolog lanL Streptomyces cyanogenus
19
A4X6Z8_SALTO
(A4X6Z8)
[query] 1 - 314 (318)
[subject] 1 - 309 (319)
1e-87 327   55% Cyclase/dehydrase Strop_2197 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
20
Q935Z5_9ACTO
(Q935Z5)
[query] 1 - 314 (318)
[subject] 1 - 308 (452)
2e-87 327   55% RdmK rdmK Streptomyces purpurascens
21
Q54490_STRNO
(Q54490)
Jump to Nogl_00320
[query] 2 - 317 (318)
[subject] 6 - 319 (323)
3e-87 325   55% SnoaE snoaE Streptomyces nogalater
22
Q6VMJ1_STRAM
(Q6VMJ1)
[query] 5 - 318 (318)
[subject] 2 - 313 (314)
1e-86 324   53% Putative bifunctional cyclase/dehydrase
Putative cyclase/dehydratase
alpE
DSMT0181
Streptomyces ambofaciens
23
Q1RQS4_STRAM
(Q1RQS4)
[query] 5 - 318 (318)
[subject] 2 - 313 (314)
1e-86 324   53% Putative cyclase/dehydratase alpE
SAMT0161
SAMT0162
Streptomyces ambofaciens ATCC 23877
24
D1H099_9ACTO
(D1H099)
[query] 1 - 310 (318)
[subject] 1 - 305 (314)
1e-86 323   55% Putative bifunctional cyclase/dehydratase chryK Streptomyces albaduncus
25
Q84CJ3_9ACTO
(Q84CJ3)
[query] 5 - 317 (318)
[subject] 2 - 310 (311)
3e-86 322   52% Cyclase/dehydratase-like protein kinD Streptomyces murayamaensis
26
Q56167_9ACTO
(Q56167)
Jump to Jado_00120
[query] 5 - 318 (318)
[subject] 2 - 310 (310)
6e-81 304   53% Bifunctional cyclase/dehydrase Streptomyces venezuelae
27
B5HJY1_STRPR
(B5HJY1)
[query] 9 - 314 (318)
[subject] 9 - 311 (318)
7e-80 301   51% Cyclase SSDG_05478 Streptomyces pristinaespiralis ATCC 25486
28
Q8VWB6_9ACTO
(Q8VWB6)
[query] 9 - 317 (318)
[subject] 8 - 311 (450)
9e-79 297   53% AknE1 aknE1 Streptomyces galilaeus
29
D1H0K2_9ACTO
(D1H0K2)
[query] 1 - 310 (318)
[subject] 1 - 307 (315)
2e-78 296   53% Putative aromatase/cyclase ravK Streptomyces sp. C23201NS3
30
Q9L554_9ACTO
(Q9L554)
Jump to Acla_00040
[query] 9 - 317 (318)
[subject] 8 - 311 (450)
2e-78 296   53% AknE1 aknE1 Streptomyces galilaeus
31
B5G889_9ACTO
(B5G889)
[query] 6 - 314 (318)
[subject] 5 - 308 (450)
6e-77 291   52% AknE1 SSBG_00497 Streptomyces sp. SPB74
32
A1C174_9ACTO
(A1C174)
Jump to Aran_00060
[query] 9 - 318 (318)
[subject] 7 - 312 (314)
7e-77 291   50% Cyclase Streptomyces echinatus
33
D1SF84_9ACTO
(D1SF84)
[query] 5 - 318 (318)
[subject] 2 - 308 (310)
3e-76 289   51% Cyclase/dehydrase MicauDRAFT_4877 Micromonospora aurantiaca ATCC 27029
34
D3CL61_9ACTO
(D3CL61)
[query] 5 - 318 (318)
[subject] 2 - 308 (310)
4e-76 288   51% Cyclase/dehydrase ML5DRAFT_6299 Micromonospora sp. L5
35
Q54811_STRPE
(Q54811)
Jump to Adria_00240
[query] 1 - 314 (318)
[subject] 1 - 311 (315)
9e-76 287   50% Daunorubicin-doxorubicin polyketide synthase dpsF Streptomyces peucetius
36
Q55220_STRSQ
(Q55220)
Jump to Dauno_00130
[query] 1 - 314 (318)
[subject] 1 - 311 (315)
4e-75 285   50% Cyclase/dehydrase dauA Streptomyces sp
37
Q4R0M7_STRCX
(Q4R0M7)
Jump to Chart_00050
[query] 1 - 316 (318)
[subject] 1 - 311 (322)
5e-73 278   49% ChaF protein chaF Streptomyces chartreusis
38
D1VCT0_9ACTO
(D1VCT0)
[query] 8 - 308 (318)
[subject] 17 - 321 (341)
4e-69 265   48% Putative uncharacterized protein FraEuI1cDRAFT_2506 Frankia sp. EuI1c
39
B7TX46_9ACTO
(B7TX46)
[query] 35 - 251 (318)
[subject] 1 - 214 (214)
2e-68 263   59% Putative cyclase/dehydratase Streptomyces sp. 6G13
40
D1A6S1_THECD
(D1A6S1)
[query] 8 - 316 (318)
[subject] 27 - 331 (340)
3e-68 263   46% Cyclase/dehydrase Tcur_2780 Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081)
41
C9NH99_9ACTO
(C9NH99)
[query] 4 - 314 (318)
[subject] 33 - 341 (347)
1e-67 260   49% Cyclase/dehydrase SflaDRAFT_5446 Streptomyces flavogriseus ATCC 33331
42
Q83X42_STRRO
(Q83X42)
[query] 9 - 316 (318)
[subject] 12 - 316 (321)
3e-67 259   48% Cyclase/aromatase rocH Streptomyces rochei
Streptomyces parvullus
43
Q2J5J6_FRASC
(Q2J5J6)
[query] 4 - 307 (318)
[subject] 2 - 303 (319)
3e-67 259   48% Actinorhodin polyketide synthase bifunctional cyclase/dehydratase Francci3_4098 Frankia sp. (strain CcI3)
44
CYPK_STRVN
(P16560)
Jump to Grana_00290
[query] 1 - 314 (318)
[subject] 11 - 321 (324)
3e-67 259   46% Granaticin polyketide synthase bifunctional cyclase/dehydratase gra-orf4 Streptomyces violaceoruber
45
B3VP10_9BACT
(B3VP10)
[query] 36 - 251 (318)
[subject] 1 - 213 (213)
3e-66 256   59% Putative cyclase/dehydratase uncultured bacterium
46
Q9X464_STRAE
(Q9X464)
[query] 4 - 317 (318)
[subject] 5 - 315 (315)
5e-66 255   47% Aromatase ncnD Streptomyces arenae
47
CYPK_STRCO
(Q02055)
Jump to Actino_00210
[query] 1 - 309 (318)
[subject] 1 - 307 (316)
9e-66 254   48% Actinorhodin polyketide synthase bifunctional cyclase/dehydratase
actI ORF4
ACTVII
SCO5090
SCBAC28G1.16
Streptomyces coelicolor
48
CYPK_STRCM
(P41178)
[query] 5 - 305 (318)
[subject] 2 - 298 (304)
1e-65 253   46% Granaticin polyketide synthase bifunctional cyclase/dehydratase
ORF4
Streptomyces cinnamonensis
49
Q3S8Q5_STRRM
(Q3S8Q5)
[query] 1 - 316 (318)
[subject] 1 - 313 (317)
2e-64 250   46% OxyK oxyK Streptomyces rimosus
50
B3VNY8_9ACTO
(B3VNY8)
[query] 35 - 251 (318)
[subject] 1 - 214 (214)
2e-64 250   58% Putative cyclase/dehydratase Micromonospora sp. 8g107
accessionDBtoolalignmentEvalueScoreIdent.linkinformationpubmed
1
Q7WT27_9ACTO
(Q7WT27)
[query] 1 - 318 (318)
[subject] 1 - 318 (318)
0.0 642   100%
Product
First ring aromatase (ARO)
Gene
med-ORF19
Organism
Streptomyces sp. AM-7161
1uniprot
Cloning, sequencing and heterologous expression of the medermycin biosynthetic gene cluster of Streptomyces sp. AM-7161: towards comparative analysis of the benzoisochromanequione gene clusters.(Microbiology (Mosc.)) [2003]
2
Q2HR24_9ACTO
(Q2HR24)
Jump to Sch475_00340
[query] 5 - 318 (318)
[subject] 2 - 312 (312)
1e-107 391   61%
Product
Putative aromatase
Gene
schP4
Organism
Streptomyces sp. SCC 2136
1uniprot
Molecular cloning and characterization of biosynthetic genes cluster of Sch 47554 from Streptomyces sp. SCC 2136. [2004]
3
C4NYK3_9ACTO
(C4NYK3)
[query] 1 - 314 (318)
[subject] 1 - 310 (314)
1e-100 368   59%
Product
SaqL
Gene
saqL
Organism
Micromonospora sp. Tu 6368
1uniprot[Pubmed] 17497146
A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007]
2uniprot[Pubmed] 19384899
Cloning and sequencing of the biosynthetic gene cluster for saquayamycin z and galtamycin B and the elucidation of the assembly of their saccharide chains.(Chembiochem) [2009]
[pubmed all]
4
Q54221_STRGR
(Q54221)
Jump to Griseu_00050
[query] 1 - 317 (318)
[subject] 1 - 313 (319)
2e-99 366   58%
Product
Putative cyclase/dehydrase
Gene
 
Organism
Streptomyces griseus
1uniprot[Pubmed] 8169211 [Medline] 94222841
Cloning, sequencing, and analysis of the griseusin polyketide synthase gene cluster from Streptomyces griseus.(J. Bacteriol.) [1994]
6
Q9AMI9_STRAT
(Q9AMI9)
[query] 11 - 317 (318)
[subject] 11 - 314 (315)
1e-96 357   57%
Product
Putative cyclase/dehydrase SimA5
Sim6
Gene
simA5
sim6
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 11959542 [Medline] 21955989
Biosynthetic gene cluster of simocyclinone, a natural multihybrid antibiotic.(Antimicrob. Agents Chemother.) [2002]
2uniprot[Pubmed] 12115055 [Medline] 22109063
Cloning and analysis of the simocyclinone biosynthetic gene cluster of Streptomyces antibioticus Tu 6040.(Arch. Microbiol.) [2002]
[pubmed all]
7
Q47QK9_THEFY
(Q47QK9)
[query] 3 - 318 (318)
[subject] 2 - 314 (314)
2e-96 356   58%
Product
Actinorhodin polyketide synthase bifunctional cyclase/dehydratase
Gene
Tfu_1222
Organism
Thermobifida fusca (strain YX)
1uniprot[Pubmed] 17209016
Genome sequence and analysis of the soil cellulolytic actinomycete Thermobifida fusca YX.(J. Bacteriol.) [2007]
8
D2XDY3_9PSEU
(D2XDY3)
[query] 1 - 317 (318)
[subject] 1 - 315 (316)
2e-95 352   55%
Product
AzicE
Gene
azicE
Organism
Kibdelosporangium sp. MJ126-NF4
1uniprot[Pubmed] 19928906
Biosynthetic studies of aziridine formation in azicemicins.(J. Am. Chem. Soc.) [2009]
10
Q93M00_STRAU
(Q93M00)
[query] 1 - 317 (318)
[subject] 1 - 313 (316)
3e-95 352   56%
Product
Cyclase/dehydratase-like protein
Gene
aur2F
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 15497441
Cloning and characterization of a new polyketide synthase gene cluster in Streptomyces aureofaciens CCM 3239.(DNA Seq.) [2004]
11
Q56H98_STRAU
(Q56H98)
[query] 1 - 314 (318)
[subject] 1 - 310 (320)
5e-95 351   57%
Product
Aur1H
Gene
aur1H
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 12384301 [Medline] 22271582
Cloning and characterization of a polyketide synthase gene cluster involved in biosynthesis of a proposed angucycline-like polyketide auricin in Streptomyces aureofaciens CCM 3239.(Gene) [2002]
2uniprot[Pubmed] 16079347
Characterization of a regulatory gene essential for the production of the angucycline-like polyketide antibiotic auricin in Streptomyces aureofaciens CCM 3239.(Microbiology) [2005]
[pubmed all]
13
Q93LY0_9ACTO
(Q93LY0)
[query] 1 - 317 (318)
[subject] 1 - 313 (314)
8e-94 347   56%
Product
Putative bifunctional aromatase PgaL
Gene
pgaL
Organism
Streptomyces sp. PGA64
1uniprot[Pubmed] 12654660 [Medline] 22540650
Engineering anthracycline biosynthesis toward angucyclines.(Antimicrob. Agents Chemother.) [2003]
2uniprot[Pubmed] 15515887
Partial activation of a silent angucycline-type gene cluster from a rubromycin beta producing Streptomyces sp. PGA64.(J. Antibiot.) [2004]
[pubmed all]
14
C7QAF6_CATAD
(C7QAF6)
[query] 1 - 318 (318)
[subject] 1 - 315 (316)
2e-93 346   54%
Product
Cyclase/dehydrase
Gene
Caci_3550
Organism
Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
1uniprot
Complete genome sequence of Catenulispora acidiphila type strain (ID 139908T).(Stand. Genomic Sci.) [2009]
15
Q9RPB1_STRFR
(Q9RPB1)
Jump to Urd_00160
[query] 5 - 318 (318)
[subject] 2 - 311 (311)
2e-92 343   55%
Product
Cyclase
Gene
urdL
Organism
Streptomyces fradiae
1uniprot[Pubmed] 10658661 [Medline] 20121748
Two new tailoring enzymes, a glycosyltransferase and an oxygenase, involved in biosynthesis of the angucycline antibiotic urdamycin A in Streptomyces fradiae Tu2717.(Microbiology) [2000]
17
Q2J5F1_FRASC
(Q2J5F1)
[query] 2 - 318 (318)
[subject] 5 - 318 (318)
4e-90 335   54%
Product
Actinorhodin polyketide synthase bifunctional cyclase/dehydratase
Gene
Francci3_4143
Organism
Frankia sp. (strain CcI3)
1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]
18
Q9ZGD3_STRCY
(Q9ZGD3)
Jump to Lando_00070
[query] 5 - 318 (318)
[subject] 2 - 318 (319)
8e-89 331   54%
Product
Cyclase homolog
Gene
lanL
Organism
Streptomyces cyanogenus
1uniprot[Pubmed] 9933932 [Medline] 99132695
Cloning and characterization of a gene cluster from Streptomyces cyanogenus S136 probably involved in landomycin biosynthesis.(FEMS Microbiol. Lett.) [1999]
21
Q54490_STRNO
(Q54490)
Jump to Nogl_00320
[query] 2 - 317 (318)
[subject] 6 - 319 (323)
3e-87 325   55%
Product
SnoaE
Gene
snoaE
Organism
Streptomyces nogalater
1uniprot[Pubmed] 8668120 [Medline] 96242142
A gene cluster involved in nogalamycin biosynthesis from Streptomyces nogalater: sequence analysis and complementation of early-block mutations in the anthracycline pathway.(Mol. Gen. Genet.) [1996]
2uniprot[Pubmed] 9349712 [Medline] 98007868
Characterization of Streptomyces nogalater genes encoding enzymes involved in glycosylation steps in nogalamycin biosynthesis.(Mol. Gen. Genet.) [1997]
3uniprot[Pubmed] 8760909 [Medline] 96349102
Production of hybrid anthracycline antibiotics by heterologous expression of Streptomyces nogalater nogalamycin biosynthesis genes.(Microbiology) [1996]
[pubmed all]
22
Q6VMJ1_STRAM
(Q6VMJ1)
[query] 5 - 318 (318)
[subject] 2 - 313 (314)
1e-86 324   53%
Product
Putative bifunctional cyclase/dehydrase
Putative cyclase/dehydratase
Gene
alpE
DSMT0181
Organism
Streptomyces ambofaciens
1uniprot[Pubmed] 14742212
Functional angucycline-like antibiotic gene cluster in the terminal inverted repeats of the Streptomyces ambofaciens linear chromosome.(Antimicrob. Agents Chemother.) [2004]
2uniprot[Pubmed] 16952952
Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006]
[pubmed all]
23
Q1RQS4_STRAM
(Q1RQS4)
[query] 5 - 318 (318)
[subject] 2 - 313 (314)
1e-86 324   53%
Product
Putative cyclase/dehydratase
Gene
alpE
SAMT0161
SAMT0162
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16952952
Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
3uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
[pubmed all]
26
Q56167_9ACTO
(Q56167)
Jump to Jado_00120
[query] 5 - 318 (318)
[subject] 2 - 310 (310)
6e-81 304   53%
Product
Bifunctional cyclase/dehydrase
Gene
 
Organism
Streptomyces venezuelae
1uniprot[Pubmed] 7881555 [Medline] 95187308
Cloning and characterization of polyketide synthase genes for jadomycin B biosynthesis in Streptomyces venezuelae ISP5230.(Microbiology) [1994]
2uniprot
Functional characterization of the jadI gene as a cyclase forming angucyclinones.(J. Am. Chem. Soc.) [1999]
28
Q8VWB6_9ACTO
(Q8VWB6)
[query] 9 - 317 (318)
[subject] 8 - 311 (450)
9e-79 297   53%
Product
AknE1
Gene
aknE1
Organism
Streptomyces galilaeus
1uniprot[Pubmed] 12399480 [Medline] 22286521
Expression, purification, and characterization of AknX anthrone oxygenase, which is involved in aklavinone biosynthesis in Streptomyces galilaeus.(J. Bacteriol.) [2002]
30
Q9L554_9ACTO
(Q9L554)
Jump to Acla_00040
[query] 9 - 317 (318)
[subject] 8 - 311 (450)
2e-78 296   53%
Product
AknE1
Gene
aknE1
Organism
Streptomyces galilaeus
1uniprot[Pubmed] 12137949 [Medline] 22133312
Cloning and characterization of Streptomyces galilaeus aclacinomycins polyketide synthase (PKS) cluster.(Gene) [2002]
35
Q54811_STRPE
(Q54811)
Jump to Adria_00240
[query] 1 - 314 (318)
[subject] 1 - 311 (315)
9e-76 287   50%
Product
Daunorubicin-doxorubicin polyketide synthase
Gene
dpsF
Organism
Streptomyces peucetius
1uniprot[Pubmed] 7828855 [Medline] 95129838
Characterization of the Streptomyces peucetius ATCC 29050 genes encoding doxorubicin polyketide synthase.(Gene) [1994]
36
Q55220_STRSQ
(Q55220)
Jump to Dauno_00130
[query] 1 - 314 (318)
[subject] 1 - 311 (315)
4e-75 285   50%
Product
Cyclase/dehydrase
Gene
dauA
Organism
Streptomyces sp
1uniprot[Pubmed] 7928998 [Medline] 95014072
Isolation and sequence analysis of polyketide synthase genes from the daunomycin-producing Streptomyces sp. strain C5.(J. Bacteriol.) [1994]
37
Q4R0M7_STRCX
(Q4R0M7)
Jump to Chart_00050
[query] 1 - 316 (318)
[subject] 1 - 311 (322)
5e-73 278   49%
Product
ChaF protein
Gene
chaF
Organism
Streptomyces chartreusis
1uniprot[Pubmed] 15911378
Biosynthesis of the antitumor agent chartreusin involves the oxidative rearrangement of an anthracyclic polyketide.(Chem. Biol.) [2005]
42
Q83X42_STRRO
(Q83X42)
[query] 9 - 316 (318)
[subject] 12 - 316 (321)
3e-67 259   48%
Product
Cyclase/aromatase
Gene
rocH
Organism
Streptomyces rochei
Streptomyces parvullus
1uniprot[Pubmed] 12791134 [Medline] 22676866
The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism.(Mol. Microbiol.) [2003]
2uniprot[Pubmed] 10954087 [Medline] 20408175
Cloning and analysis of the replication origin and the telomeres of the large linear plasmid pSLA2-L in Streptomyces rochei.(Mol. Gen. Genet.) [2000]
3uniprot[Pubmed] 10767533 [Medline] 20231737
Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei.(Gene) [2000]
4uniprot[Pubmed] 9836424 [Medline] 99053144
Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs.(Biosci. Biotechnol. Biochem.) [1998]
[pubmed all]
43
Q2J5J6_FRASC
(Q2J5J6)
[query] 4 - 307 (318)
[subject] 2 - 303 (319)
3e-67 259   48%
Product
Actinorhodin polyketide synthase bifunctional cyclase/dehydratase
Gene
Francci3_4098
Organism
Frankia sp. (strain CcI3)
1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]
44
CYPK_STRVN
(P16560)
Jump to Grana_00290
[query] 1 - 314 (318)
[subject] 11 - 321 (324)
3e-67 259   46%
Product
Granaticin polyketide synthase bifunctional cyclase/dehydratase
Gene
gra-orf4
Organism
Streptomyces violaceoruber
1uniprot[Pubmed] 2583128 [Medline] 90060034
Structure and deduced function of the granaticin-producing polyketide synthase gene cluster of Streptomyces violaceoruber Tu22.(EMBO J.) [1989]
2uniprot[Pubmed] 7476861 [Medline] 96027933
Identification of Streptomyces violaceoruber Tu22 genes involved in the biosynthesis of granaticin.(Mol. Gen. Genet.) [1995]
3uniprot[Pubmed] 9831526 [Medline] 99051446
The granaticin biosynthetic gene cluster of Streptomyces violaceoruber Tu22: sequence analysis and expression in a heterologous host.(Chem. Biol.) [1998]
[pubmed all]
46
Q9X464_STRAE
(Q9X464)
[query] 4 - 317 (318)
[subject] 5 - 315 (315)
5e-66 255   47%
Product
Aromatase
Gene
ncnD
Organism
Streptomyces arenae
1uniprot[Pubmed] 10206788 [Medline] 99217421
Isolation and characterization of the naphthocyclinone gene cluster from Streptomyces arenae DSM 40737 and heterologous expression of the polyketide synthase genes.(Gene) [1999]
47
CYPK_STRCO
(Q02055)
Jump to Actino_00210
[query] 1 - 309 (318)
[subject] 1 - 307 (316)
9e-66 254   48%
Product
Actinorhodin polyketide synthase bifunctional cyclase/dehydratase
actI ORF4
ACTVII
Gene
SCO5090
SCBAC28G1.16
Organism
Streptomyces coelicolor
1uniprot[Pubmed] 1527048 [Medline] 92406871
Nucleotide sequence and deduced functions of a set of cotranscribed genes of Streptomyces coelicolor A3(2) including the polyketide synthase for the antibiotic actinorhodin.(J. Biol. Chem.) [1992]
2uniprot[Pubmed] 12000953 [Medline] 21996410
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002]
[pubmed all]
48
CYPK_STRCM
(P41178)
[query] 5 - 305 (318)
[subject] 2 - 298 (304)
1e-65 253   46%
Product
Granaticin polyketide synthase bifunctional cyclase/dehydratase
ORF4
Gene
 
Organism
Streptomyces cinnamonensis
1uniprot[Pubmed] 1508151 [Medline] 92374994
Characterisation of actI-homologous DNA encoding polyketide synthase genes from the monensin producer Streptomyces cinnamonensis.(Mol. Gen. Genet.) [1992]
49
Q3S8Q5_STRRM
(Q3S8Q5)
[query] 1 - 316 (318)
[subject] 1 - 313 (317)
2e-64 250   46%
Product
OxyK
Gene
oxyK
Organism
Streptomyces rimosus
1uniprot[Pubmed] 16597959
Engineered biosynthesis of a novel amidated polyketide, using the malonamyl-specific initiation module from the oxytetracycline polyketide synthase.(Appl. Environ. Microbiol.) [2006]
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