BLAST table : Pladi_00060

DB	UniProtKB

check	5 10 1..n m..n all clear

function	Sequence Feature Clustalw

export	List

	accession	tool	Evalue	Score	Ident.	link	product	gene	organism	ec
1	B6ZIR7_STRPT (B6ZIR7)	seq blast	0.0	777	100%	UniProt GenBank	Putative acyltransferase	pldC	Streptomyces platensis
2	Q2PC62_STRAH (Q2PC62)	seq blast	3e-51	206	36%	UniProt GenBank	Putative uncharacterized protein rubF3	rubF3	Streptomyces achromogenes subsp. rubradiris
3	A3KI36_STRAM (A3KI36)	seq blast	5e-40	169	37%	UniProt GenBank	Putative polyketide associated protein	SAML0377	Streptomyces ambofaciens ATCC 23877
4	C6WEG0_ACTMD (C6WEG0)	seq blast	1e-20	104	27%	UniProt GenBank	Condensation domain protein	Amir_3883	Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
5	B5GRC5_STRCL (B5GRC5)	seq blast	4e-16	90.1	30%	UniProt GenBank	Putative uncharacterized protein	SSCG_01899	Streptomyces clavuligerus ATCC 27064
6	A4TA99_MYCGI (A4TA99)	seq blast	2e-11	74.7	25%	UniProt GenBank	Acyltransferase PapA5	Mflv_3386	Mycobacterium gilvum (strain PYR-GCK) Mycobacterium flavescens (strain ATCC 700033 / PYR-GCK)
7	B1Q2P9_9NOCA (B1Q2P9)	seq blast	2e-11	74.3	29%	UniProt GenBank	Putative uncharacterized protein bra9	bra9	Nocardia brasiliensis
8	Q9AE01_AMYMD (Q9AE01)	seq blast	9e-11	72.4	29%	UniProt GenBank	Putative polyketide associated protein		Amycolatopsis mediterranei Nocardia mediterranei
9	Q10ZJ1_TRIEI (Q10ZJ1)	seq blast	9e-11	72.4	22%	UniProt GenBank	Putative uncharacterized protein	Tery_3214	Trichodesmium erythraeum (strain IMS101)
10	B9YKI9_ANAAZ (B9YKI9)	seq blast	1e-09	68.6	22%	UniProt GenBank	Alcohol acetyltransferase	AazoDRAFT_2093	'Nostoc azollae' 0708
11	B8ZT32_MYCLB (B8ZT32)	seq blast	3e-07	60.8	27%	UniProt GenBank	Putative uncharacterized protein	MLBr02349	Mycobacterium leprae (strain Br4923)
12	PAPA5_MYCLE (Q49939)	seq blast	3e-07	60.8	27%	UniProt GenBank	Phthiocerol/phthiodiolone dimycocerosyl transferase Phthiocerol/phthiodiolone O-acyltransferase Acyltransferase papA5 Polyketide synthase-associated protein A5	papA5 ML2349 MLCB2407.01	Mycobacterium leprae	2.3.1.- niceE keggE
13	C6DWB5_MYCTK (C6DWB5)	seq blast	2e-06	58.2	27%	UniProt GenBank	Polyketide synthase associated protein papA5	TBMG_01033	Mycobacterium tuberculosis (strain KZN 1435 / MDR)
14	C1AG55_MYCBT (C1AG55)	seq blast	2e-06	58.2	27%	UniProt GenBank	Acyltransferase	papA5 JTY_2956	Mycobacterium bovis (strain BCG / Tokyo 172 / ATCC 35737 / TMC 1019)
15	A5WRJ1_MYCTF (A5WRJ1)	seq blast	2e-06	58.2	27%	UniProt GenBank	Polyketide synthase associated protein papA5	TBFG_12953	Mycobacterium tuberculosis (strain F11)
16	A4KKJ9_MYCTU (A4KKJ9)	seq blast	2e-06	58.2	27%	UniProt GenBank	Polyketide synthase associated protein papA5	TBHG_02869	Mycobacterium tuberculosis str. Haarlem
17	A2VLR5_MYCTU (A2VLR5)	seq blast	2e-06	58.2	27%	UniProt GenBank	Polyketide synthase associated protein papA5	TBCG_02877	Mycobacterium tuberculosis C
18	PAPA5_MYCTU (P96208)	seq blast	2e-06	58.2	27%	UniProt GenBank	Phthiocerol/phthiodiolone dimycocerosyl transferase Phthiocerol/phthiodiolone O-acyltransferase Acyltransferase papA5 Polyketide synthase-associated protein A5	papA5 Rv2939 MT3009 MTCY19H9.07	Mycobacterium tuberculosis	2.3.1.- niceE keggE
19	PAPA5_MYCTA (A5U6U6)	seq blast	2e-06	58.2	27%	UniProt GenBank	Phthiocerol/phthiodiolone dimycocerosyl transferase Phthiocerol/phthiodiolone O-acyltransferase Acyltransferase papA5 Polyketide synthase-associated protein A5	papA5 MRA_2965	Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)	2.3.1.- niceE keggE
20	PAPA5_MYCBP (A1KMT4)	seq blast	2e-06	58.2	27%	UniProt GenBank	Phthiocerol/phthiodiolone dimycocerosyl transferase Phthiocerol/phthiodiolone O-acyltransferase Acyltransferase papA5 Polyketide synthase-associated protein A5	papA5 BCG_2961	Mycobacterium bovis (strain BCG / Pasteur 1173P2)	2.3.1.- niceE keggE
21	PAPA5_MYCBO (Q02279)	seq blast	2e-06	58.2	27%	UniProt GenBank	Phthiocerol/phthiodiolone dimycocerosyl transferase Phthiocerol/phthiodiolone O-acyltransferase Acyltransferase papA5 Polyketide synthase-associated protein A5	papA5 Mb2964	Mycobacterium bovis	2.3.1.- niceE keggE
22	C2ARF2_TSUPA (C2ARF2)	seq blast	2e-06	57.8	26%	UniProt GenBank	Putative uncharacterized protein	TpauDRAFT_29630	Tsukamurella paurometabola DSM 20162
23	PAPA5_MYCSS (Q1B849)	seq blast	4e-06	57	24%	UniProt GenBank	Phthiocerol/phthiodiolone dimycocerosyl transferase Phthiocerol/phthiodiolone O-acyltransferase Acyltransferase papA5 Polyketide synthase-associated protein A5	papA5 Mmcs_2828	Mycobacterium sp. (strain MCS)	2.3.1.- niceE keggE
24	PAPA5_MYCSK (A1UGV8)	seq blast	4e-06	57	24%	UniProt GenBank	Phthiocerol/phthiodiolone dimycocerosyl transferase Phthiocerol/phthiodiolone O-acyltransferase Acyltransferase papA5 Polyketide synthase-associated protein A5	papA5 Mkms_2872	Mycobacterium sp. (strain KMS)	2.3.1.- niceE keggE
25	PAPA5_MYCSJ (A3Q0G0)	seq blast	4e-06	57	24%	UniProt GenBank	Phthiocerol/phthiodiolone dimycocerosyl transferase Phthiocerol/phthiodiolone O-acyltransferase Acyltransferase papA5 Polyketide synthase-associated protein A5	papA5 Mjls_2857	Mycobacterium sp. (strain JLS)	2.3.1.- niceE keggE
26	A8M6E2_SALAI (A8M6E2)	seq blast	7e-06	56.2	26%	UniProt GenBank	Conserved polyketide synthase associated protein PapA5	Sare_1262	Salinispora arenicola (strain CNS-205)
27	PAPA5_MYCUA (A0PQ31)	seq blast	1e-05	55.5	26%	UniProt GenBank	Phthiocerol/phthiodiolone dimycocerosyl transferase Phthiocerol/phthiodiolone O-acyltransferase Acyltransferase papA5 Polyketide synthase-associated protein A5	papA5 MUL_2011	Mycobacterium ulcerans (strain Agy99)	2.3.1.- niceE keggE
28	B2HIM3_MYCMM (B2HIM3)	seq blast	1e-05	55.5	26%	UniProt GenBank	Conserved polyketide synthase associated protein PapA5	papA5 MMAR_1768	Mycobacterium marinum (strain ATCC BAA-535 / M)
29	B1MML4_MYCA9 (B1MML4)	seq blast	7e-05	52.8	37%	UniProt GenBank	Possible conserved polyketide synthase associated protein	MAB_4931	Mycobacterium abscessus (strain ATCC 19977 / DSM 44196)
30	B1FD64_9BURK (B1FD64)	seq blast	0.0001	52	26%	UniProt GenBank	Condensation domain protein	BamIOP4010DRAFT_1973	Burkholderia ambifaria IOP40-10
31	B3RAA4_CUPTR (B3RAA4)	seq blast	0.0002	51.6	37%	UniProt GenBank	Non ribosomal peptide synthase, antibiotic synthesis; contains 4 condensation domains, 3 AMP-acid ligases II domains, 3 PP-binding, Phosphopantetheine attachment site and a putative thioesterase domain	RALTA_B1228	Cupriavidus taiwanensis (strain R1 / LMG 19424) Ralstonia taiwanensis (strain LMG 19424)	1.1.-.- niceE keggE
32	Q4K992_PSEF5 (Q4K992)	seq blast	0.0002	51.6	32%	UniProt GenBank	Nonribosomal peptide synthetase	PFL_4094	Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477)
33	C1F4N9_ACIC5 (C1F4N9)	seq blast	0.0002	50.8	32%	UniProt GenBank	Polyketide synthase peptide synthetase fusion protein	ACP_1157	Acidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670)	5.1.1.11 niceE keggE
34	B4UXS6_9ACTO (B4UXS6)	seq blast	0.0003	50.8	27%	UniProt GenBank	Putative uncharacterized protein	SSAG_00432	Streptomyces sp. Mg1
35	Q51338_PSEAE (Q51338)	seq blast	0.0004	50.1	31%	UniProt GenBank	Pyoverdine synthetase D	pvdD	Pseudomonas aeruginosa
36	Q9I182_PSEAE (Q9I182)	seq blast	0.0004	50.1	31%	UniProt GenBank	Pyoverdine synthetase D	pvdD PA2399	Pseudomonas aeruginosa
37	Q02MJ3_PSEAB (Q02MJ3)	seq blast	0.0004	50.1	31%	UniProt GenBank	Pyoverdine synthetase D	pvdD PA14_33650	Pseudomonas aeruginosa (strain UCBPP-PA14)
38	A3L655_PSEAE (A3L655)	seq blast	0.0004	50.1	31%	UniProt GenBank	Pyoverdine synthetase D	PA2G_01504	Pseudomonas aeruginosa 2192
39	Q5DIV9_PSEAE (Q5DIV9)	seq blast	0.0004	50.1	31%	UniProt GenBank	PvdD	pvdD	Pseudomonas aeruginosa
40	A3WXS0_9BRAD (A3WXS0)	seq blast	0.0005	50.1	31%	UniProt GenBank	Probable non-ribosomal peptide synthetase	NB311A_17044	Nitrobacter sp. Nb-311A
41	B8EPL1_METSB (B8EPL1)	seq blast	0.0007	49.3	31%	UniProt GenBank	Amino acid adenylation domain protein	Msil_1247	Methylocella silvestris (strain BL2 / DSM 15510 / NCIMB 13906)
42	C3K9F4_PSEFS (C3K9F4)	seq blast	0.0008	49.3	32%	UniProt GenBank	Pvdj(2)	pvdJ PFLU_2544	Pseudomonas fluorescens (strain SBW25)

accession

tool

alignment

Evalue

Score

Ident.

link

information

pubmed

B6ZIR7_STRPT
(B6ZIR7)

0.0

777

100%

Product: Putative acyltransferase
Gene: pldC
Organism: Streptomyces platensis

1uniprot[Pubmed] 18997414
Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008]

Q2PC62_STRAH
(Q2PC62)

3e-51

206

36%

Product: Putative uncharacterized protein rubF3
Gene: rubF3
Organism: Streptomyces achromogenes subsp. rubradiris

[pubmed all]
1uniprot[Pubmed] 9387157 [Medline] 98048398 Identification of a gene cluster of biosynthetic genes of rubradirin substructures in S. achromogenes var. rubradiris NRRL3061.(Mol. Cells) [1997]
2uniprot[Pubmed] 12889805 [Medline] 22771458 Functional identification of rub52 gene involved in the biosynthesis of rubradirin.(Biotechnol. Lett.) [2003]

A3KI36_STRAM
(A3KI36)

5e-40

169

37%

Product: Putative polyketide associated protein
Gene: SAML0377
Organism: Streptomyces ambofaciens ATCC 23877

1uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]

C6WEG0_ACTMD
(C6WEG0)

1e-20

104

27%

Product: Condensation domain protein
Gene: Amir_3883
Organism: Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)

1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101T).(Stand. Genomic Sci.) [2009]

B1Q2P9_9NOCA
(B1Q2P9)

2e-11

74.3

29%

Product: Putative uncharacterized protein bra9
Gene: bra9
Organism: Nocardia brasiliensis

1uniprot[Pubmed] 18503195
Cloning of the gene cluster responsible for the biosynthesis of brasilicardin A, a unique diterpenoid.(J. Antibiot.) [2008]

Q9AE01_AMYMD
(Q9AE01)

9e-11

72.4

29%

Product: Putative polyketide associated protein
Gene
Organism: Amycolatopsis mediterranei
Nocardia mediterranei

[pubmed all]
1uniprot[Pubmed] 9512878 [Medline] 98174059 Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.(Chem. Biol.) [1998]
2uniprot[Pubmed] 9497318 [Medline] 98165773 3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.(J. Biol. Chem.) [1998]
3uniprot[Pubmed] 11278540 [Medline] 21201076 Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.(J. Biol. Chem.) [2001]

B8ZT32_MYCLB
(B8ZT32)

3e-07

60.8

27%

Product: Putative uncharacterized protein
Gene: MLBr02349
Organism: Mycobacterium leprae (strain Br4923)

1uniprot[Pubmed] 19881526
Comparative genomic and phylogeographic analysis of Mycobacterium leprae.(Nat. Genet.) [2009]

PAPA5_MYCLE
(Q49939)

3e-07

60.8

27%

Product: Phthiocerol/phthiodiolone dimycocerosyl transferase
Phthiocerol/phthiodiolone O-acyltransferase
Acyltransferase papA5
Polyketide synthase-associated protein A5
Gene: papA5
ML2349
MLCB2407.01
Organism: Mycobacterium leprae

1uniprot[Pubmed] 11234002 [Medline] 21128732
Massive gene decay in the leprosy bacillus.(Nature) [2001]

C1AG55_MYCBT
(C1AG55)

2e-06

58.2

27%

Product: Acyltransferase
Gene: papA5
JTY_2956
Organism: Mycobacterium bovis (strain BCG / Tokyo 172 / ATCC 35737 / TMC 1019)

1uniprot[Pubmed] 19200449
Whole genome sequence analysis of Mycobacterium bovis bacillus Calmette-Guerin (BCG) Tokyo 172: a comparative study of BCG vaccine substrains.(Vaccine) [2009]

PAPA5_MYCTU
(P96208)

2e-06

58.2

27%

Product: Phthiocerol/phthiodiolone dimycocerosyl transferase
Phthiocerol/phthiodiolone O-acyltransferase
Acyltransferase papA5
Polyketide synthase-associated protein A5
Gene: papA5
Rv2939
MT3009
MTCY19H9.07
Organism: Mycobacterium tuberculosis

[pubmed all]
1uniprot[Pubmed] 9634230 [Medline] 98295987 Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.(Nature) [1998]
2uniprot[Pubmed] 12218036 [Medline] 22206494 Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains.(J. Bacteriol.) [2002]
3uniprot[Pubmed] 15070765 Mycobacterial polyketide-associated proteins are acyltransferases: proof of principle with Mycobacterium tuberculosis PapA5.(Proc. Natl. Acad. Sci. U.S.A.) [2004]
4uniprot[Pubmed] 15749014 Dissecting the mechanism and assembly of a complex virulence mycobacterial lipid.(Mol. Cell) [2005]
5uniprot[Pubmed] 19099550 targetTB: a target identification pipeline for Mycobacterium tuberculosis through an interactome, reactome and genome-scale structural analysis.(BMC Syst. Biol.) [2008]
6uniprot[Pubmed] 15123643 Crystal structure of PapA5, a phthiocerol dimycocerosyl transferase from Mycobacterium tuberculosis.(J. Biol. Chem.) [2004]

PAPA5_MYCBP
(A1KMT4)

2e-06

58.2

27%

Product: Phthiocerol/phthiodiolone dimycocerosyl transferase
Phthiocerol/phthiodiolone O-acyltransferase
Acyltransferase papA5
Polyketide synthase-associated protein A5
Gene: papA5
BCG_2961
Organism: Mycobacterium bovis (strain BCG / Pasteur 1173P2)

1uniprot[Pubmed] 17372194
Genome plasticity of BCG and impact on vaccine efficacy.(Proc. Natl. Acad. Sci. U.S.A.) [2007]

PAPA5_MYCBO
(Q02279)

2e-06

58.2

27%

Product: Phthiocerol/phthiodiolone dimycocerosyl transferase
Phthiocerol/phthiodiolone O-acyltransferase
Acyltransferase papA5
Polyketide synthase-associated protein A5
Gene: papA5
Mb2964
Organism: Mycobacterium bovis

[pubmed all]
1uniprot[Pubmed] 1527058 [Medline] 92406887 Molecular cloning and sequencing of the gene for mycocerosic acid synthase, a novel fatty acid elongating multifunctional enzyme, from Mycobacterium tuberculosis var. bovis Bacillus Calmette-Guerin.(J. Biol. Chem.) [1992]
2uniprot[Pubmed] 12788972 [Medline] 22709107 The complete genome sequence of Mycobacterium bovis.(Proc. Natl. Acad. Sci. U.S.A.) [2003]

PAPA5_MYCUA
(A0PQ31)

1e-05

55.5

26%

Product: Phthiocerol/phthiodiolone dimycocerosyl transferase
Phthiocerol/phthiodiolone O-acyltransferase
Acyltransferase papA5
Polyketide synthase-associated protein A5
Gene: papA5
MUL_2011
Organism: Mycobacterium ulcerans (strain Agy99)

1uniprot[Pubmed] 17210928
Reductive evolution and niche adaptation inferred from the genome of Mycobacterium ulcerans, the causative agent of Buruli ulcer.(Genome Res.) [2007]

B2HIM3_MYCMM
(B2HIM3)

1e-05

55.5

26%

Product: Conserved polyketide synthase associated protein PapA5
Gene: papA5
MMAR_1768
Organism: Mycobacterium marinum (strain ATCC BAA-535 / M)

1uniprot[Pubmed] 18403782
Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis.(Genome Res.) [2008]

B3RAA4_CUPTR
(B3RAA4)

0.0002

51.6

37%

Product: Non ribosomal peptide synthase, antibiotic synthesis; contains 4 condensation domains, 3 AMP-acid ligases II domains, 3 PP-binding, Phosphopantetheine attachment site and a putative thioesterase domain
Gene: RALTA_B1228
Organism: Cupriavidus taiwanensis (strain R1 / LMG 19424)
Ralstonia taiwanensis (strain LMG 19424)

1uniprot[Pubmed] 18490699
Genome sequence of the beta-rhizobium Cupriavidus taiwanensis and comparative genomics of rhizobia.(Genome Res.) [2008]

Q4K992_PSEF5
(Q4K992)

0.0002

51.6

32%

Product: Nonribosomal peptide synthetase
Gene: PFL_4094
Organism: Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477)

1uniprot[Pubmed] 15980861
Complete genome sequence of the plant commensal Pseudomonas fluorescens Pf-5.(Nat. Biotechnol.) [2005]

C1F4N9_ACIC5
(C1F4N9)

0.0002

50.8

32%

Product: Polyketide synthase peptide synthetase fusion protein
Gene: ACP_1157
Organism: Acidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670)

1uniprot[Pubmed] 19201974
Three genomes from the phylum Acidobacteria provide insight into the lifestyles of these microorganisms in soils.(Appl. Environ. Microbiol.) [2009]

Q51338_PSEAE
(Q51338)

0.0004

50.1

31%

Product: Pyoverdine synthetase D
Gene: pvdD
Organism: Pseudomonas aeruginosa

[pubmed all]
1uniprot[Pubmed] 8335619 [Medline] 93328663 Cloning and nucleotide sequence analysis of the ferripyoverdine receptor gene fpvA of Pseudomonas aeruginosa.(J. Bacteriol.) [1993]
2uniprot[Pubmed] 7798141 [Medline] 95095977 Nucleotide sequence of pvdD, a pyoverdine biosynthetic gene from Pseudomonas aeruginosa: PvdD has similarity to peptide synthetases.(J. Bacteriol.) [1995]
3uniprot[Pubmed] 7891666 [Medline] 95198690 Identification of a DNA sequence motif required for expression of iron-regulated genes in pseudomonads.(Mol. Gen. Genet.) [1995]

Q9I182_PSEAE
(Q9I182)

0.0004

50.1

31%

Product: Pyoverdine synthetase D
Gene: pvdD
PA2399
Organism: Pseudomonas aeruginosa

1uniprot[Pubmed] 10984043 [Medline] 20437337
Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen.(Nature) [2000]

Q02MJ3_PSEAB
(Q02MJ3)

0.0004

50.1

31%

Product: Pyoverdine synthetase D
Gene: pvdD
PA14_33650
Organism: Pseudomonas aeruginosa (strain UCBPP-PA14)

1uniprot[Pubmed] 17038190
Genomic analysis reveals that Pseudomonas aeruginosa virulence is combinatorial.(Genome Biol.) [2006]

A3L655_PSEAE
(A3L655)

0.0004

50.1

31%

Product: Pyoverdine synthetase D
Gene: PA2G_01504
Organism: Pseudomonas aeruginosa 2192

1uniprot[Pubmed] 18287045
Dynamics of Pseudomonas aeruginosa genome evolution.(Proc. Natl. Acad. Sci. U.S.A.) [2008]

Q5DIV9_PSEAE
(Q5DIV9)

0.0004

50.1

31%

Product: PvdD
Gene: pvdD
Organism: Pseudomonas aeruginosa

1uniprot[Pubmed] 15743962
Evidence for diversifying selection at the pyoverdine locus of Pseudomonas aeruginosa.(J. Bacteriol.) [2005]

C3K9F4_PSEFS
(C3K9F4)

0.0008

49.3

32%

Product: Pvdj(2)
Gene: pvdJ
PFLU_2544
Organism: Pseudomonas fluorescens (strain SBW25)

1uniprot[Pubmed] 19432983
Genomic and genetic analyses of diversity and plant interactions of Pseudomonas fluorescens.(Genome Biol.) [2009]