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Cluster information : Steffimycin


close this sectionCompound

Entry nameSteffimycin
PKS TypeTypeII
Starter Unitacetyl-CoA
Chain Length10
Sugar Unit2-O-methyl-L-rhamnose
ClassificationAnthracycline
ActivityAntitumor
CompositionC28H30O13
Steffimycin

close this sectionOriginal source

Organism
StrainNRRL 3193 (=NBRC 13446)
Contig
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close this sectionPKS/NRPS Module

KS3..375
CLF4..361
ACP5..79

close this sectionReference

Isolation, characterization, and heterologous expression of the biosynthesis gene cluster for the antitumor anthracycline steffimycin.
Gullon S, Olano C, Abdelfattah MS, Brana AF, Rohr J, Mendez C, Salas JA
[PMID: 16751529]Appl Environ Microbiol. 72 (2006) 4172-83
Glycosylated derivatives of steffimycin: insights into the role of the sugar moieties for the biological activity.
Olano C, Abdelfattah MS, Gullon S, Brana AF, Rohr J, Mendez C, Salas JA
[PMID: 18224649]Chembiochem. 9 (2008) 624-33

close this sectionData download

Compound nameGenomic
nucleotide
sequence
Nucleotide
sequences of the
coding regions
Translation of the
coding sequences
List of genes/ORFsGBK
Steffimycin
Genomic nucleotide sequence
43 KB
Nucleotide sequences of the coding regions
42 KB
Translation of the coding sequences
16 KB
List of genes/ORFs
5 KB

 

 
GenBank format
88 KB

close this sectionHistory

  • 2012-10-02[Release]