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Cluster information : Polyketomycin


close this sectionCompound

Entry namePolyketomycin
Moiety descriptionA: aglycone
B: 3,6-dimethylsalicylic acid moiety
PKS TypeA: TypeII
B: TypeI iterative
Starter UnitA: acetyl-CoA
B: acetyl-CoA
Chain LengthA: 10
B: 4
Sugar Unitalpha-L-axenose
beta-D-amicetose
ClassificationTetracyclic quinone glycoside
ActivityAntibacterial
Antitumor
CompositionC44H48O18
Polyketomycin

close this sectionOriginal source

Organism
StrainTü6028
Contig
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close this sectionPKS/NRPS Module

A
BPolk_00160
pokM1
1 acetyl-CoA
malonyl-CoA
KS3..374
CLF2..364
ACP5..78
KS6..380
AT542..857
TH865..1011
KR1369..1562
ACP1645..1722

close this sectionReference

Organisation of the biosynthetic gene cluster and tailoring enzymes in the biosynthesis of the tetracyclic quinone glycoside antibiotic polyketomycin.
Daum M, Peintner I, Linnenbrink A, Frerich A, Weber M, Paululat T, Bechthold A
[PMID: 19266534]Chembiochem. 10 (2009) 1073-83

close this sectionData download

Compound nameGenomic
nucleotide
sequence
Nucleotide
sequences of the
coding regions
Translation of the
coding sequences
List of genes/ORFsGBK
Polyketomycin
Genomic nucleotide sequence
53 KB
Nucleotide sequences of the coding regions
52 KB
Translation of the coding sequences
19 KB
List of genes/ORFs
6 KB

 

 
GenBank format
114 KB

close this sectionHistory

  • 2016-01-27[Update]
  • 2013-05-28[Update]
  • 2013-01-16[Update]
  • 2012-10-02[Release]