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Cluster information : Pyoluteorin
Compound
| Entry name | Pyoluteorin |
|---|---|
| PKS Type | PKS-NRPS hybrid |
| Classification | Pyrrole Antibiotic |
| Starter Unit | L-proline |
| Chain Length | 3 |
| Sugar Unit | none |
| Activity | Antibacterial Antifungal |
| Composition | C11H7Cl2NO3 |
Original source
| Organism | Pseudomonas fluorescens |
|---|---|
| Strain | Pf-5 |
| Contig | AF081920 |
PKS/NRPS Module
| Pyolu_00050 pltB | 1 |  | malonyl-CoA |
| 2 |  | malonyl-CoA | |
| Pyolu_00060 pltC | 3 |  | malonyl-CoA |
| |||
Reference
- Identification and sequence analysis of the genes encoding a polyketide synthase required for pyoluteorin biosynthesis in Pseudomonas fluorescens Pf-5.
- Nowak-Thompson B, Gould SJ, Loper JE[PMID: 9434161]Gene. 204 (1997) 17-24
- Characterization of the pyoluteorin biosynthetic gene cluster of Pseudomonas fluorescens Pf-5.
- Nowak-Thompson B, Chaney N, Wing JS, Gould SJ, Loper JE[PMID: 10094695]J Bacteriol. 181 (1999) 2166-74
- Conversion of L-proline to pyrrolyl-2-carboxyl-S-PCP during undecylprodigiosin and pyoluteorin biosynthesis.
- Thomas MG, Burkart MD, Walsh CT[PMID: 11880032]Chem Biol. 9 (2002) 171-84
- Dichlorination of a pyrrolyl-S-carrier protein by FADH2-dependent halogenase PltA during pyoluteorin biosynthesis.
- Dorrestein PC, Yeh E, Garneau-Tsodikova S, Kelleher NL, Walsh CT[PMID: 16162666]Proc Natl Acad Sci U S A. 102 (2005) 13843-8
- Reciprocal regulation of pyoluteorin production with membrane transporter gene expression in Pseudomonas fluorescens Pf-5.
- Brodhagen M, Paulsen I, Loper JE[PMID: 16269724]Appl Environ Microbiol. 71 (2005) 6900-9
Data download
| Compound name | Genomic nucleotide sequence |
Nucleotide sequences of the coding regions | Translation of the coding sequences | List of genes/ORFs | GBK | |||||||
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 Pyoluteorin |
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History
- 2012-03-28[Release]
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