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Cluster information : Cosmomycin


close this sectionCompound

Entry nameCosmomycin
PKS TypeTypeII
Starter Unitpropionyl-CoA
Chain Length10
Sugar UnitL-2-deoxyfucose
L-rhodinose
L-rhodosamine
ClassificationAnthracycline
ActivityAntitumor
CompositionD: C60H88N2O22
Cosmomycin

close this sectionOriginal source

Organism
StrainDAUFPE 5622
Contig
Click on the icon to see Genetic map.

close this sectionPKS/NRPS Module

KS108..335
KS3..374
CLF2..355

close this sectionReference

Insights in the glycosylation steps during biosynthesis of the antitumor anthracycline cosmomycin: characterization of two glycosyltransferase genes.
Garrido LM, Lombo F, Baig I, Nur-E-Alam M, Furlan RL, Borda CC, Brana A, Mendez C, Salas JA, Rohr J, Padilla G
[PMID: 16810496]Appl Microbiol Biotechnol. 73 (2006) 122-31
Genome Sequence of Streptomyces olindensis DAUFPE 5622, Producer of the Antitumoral Anthracycline Cosmomycin D.
Rojas JD, Starcevic A, Baranasic D, Ferreira-Torres MA, Contreras CA, Garrido LM, Araujo WL, de Souza RF, Zucko J, Hranueli D, Long PF, Cullum J, Padilla G
[PMID: 24970824]Genome Announc. 2 (2014)

close this sectionData download

Compound nameGenomic
nucleotide
sequence
Nucleotide
sequences of the
coding regions
Translation of the
coding sequences
List of genes/ORFsGBK
Cosmomycin
Genomic nucleotide sequence
14 KB
Nucleotide sequences of the coding regions
14 KB
Translation of the coding sequences
5 KB
List of genes/ORFs
2 KB

 

 
GenBank format
32 KB

close this sectionHistory

  • 2015-02-12[Update]
  • 2013-01-16[Update]
  • 2012-10-02[Release]