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Cluster information : Halstoctacosanolide


close this sectionCompound

Entry nameHalstoctacosanolide
PKS TypeTypeI modular
Starter Unitmethylmalonyl-CoA
Chain Length19
Sugar Unitnone
ClassificationOther Macrocyclic Lactone
ActivityAntibacterial
CompositionA: C48H76O12
Halstoctacosanolide

close this sectionOriginal source

Organism
StrainHC34
Contig
Click on the icon to see Genetic map.

close this sectionPKS/NRPS Module

Halsto_00010
hlsA
0 methylmalonyl-CoA
1 methylmalonyl-CoA
2 malonyl-CoA
Halsto_00020
hlsB
3 malonyl-CoA
4 methylmalonyl-CoA
5 methylmalonyl-CoA
6 malonyl-CoA
Halsto_00030
hlsC
7 methylmalonyl-CoA
8 malonyl-CoA
9 malonyl-CoA
Halsto_00040
hlsD
10 methylmalonyl-CoA
11 malonyl-CoA
12 malonyl-CoA
Halsto_00050
hlsE
13 methylmalonyl-CoA
14 malonyl-CoA
Halsto_00060
hlsF
15 methylmalonyl-CoA
16 methylmalonyl-CoA
17 malonyl-CoA
Halsto_00070
hlsG
18 methylmalonyl-CoA
KSQ6..367
AT537..851
ACP927..997
KS1019..1398
AT1553..1867
KR2197..2377
ACP2480..2550
KS2576..2954
AT3114..3430
KR3761..3941
ACP4044..4114
KS34..412
AT569..886
KR1204..1384
ACP1485..1555
KS1580..1956
AT2115..2429
DH2480..2648
KR2977..3156
ACP3260..3330
KS3354..3731
AT3888..4202
DH4253..4420
ER4787..5105
KR5114..5293
ACP5397..5467
KS5490..5865
AT6023..6339
KR6667..6843
ACP6947..7017
KS34..410
AT566..880
KR1207..1386
ACP1488..1558
KS1593..1969
AT2126..2439
DH2490..2665
KR2999..3178
ACP3279..3349
KS3372..3748
AT3907..4225
DH4271..4438
KR4778..4957
ACP5061..5131
KS34..410
AT567..881
DH932..1098
ER1442..1757
KR1766..1945
ACP2049..2119
KS2142..2517
AT2677..2995
kr3307..3486
ACP3595..3665
KS3688..4064
AT4226..4548
KR4876..5052
ACP5158..5228
KS33..409
AT564..878
DH929..1095
ER1430..1745
KR1754..1933
ACP2037..2107
KS2131..2506
AT2666..2990
kr3320..3499
ACP3644..3714
KS34..410
AT571..885
DH936..1115
KR1448..1627
ACP1731..1801
KS1827..2203
AT2359..2672
DH2723..2901
KR3241..3420
ACP3524..3594
KS3616..3992
AT4152..4473
KR4796..4978
ACP5083..5152
KS55..430
AT592..907
DH956..1134
KR1455..1634
ACP1739..1809
TE1887..2095

close this sectionReference

The complete biosynthetic gene cluster of the 28-membered polyketide macrolactones, halstoctacosanolides, from Streptomyces halstedii HC34.
Tohyama S, Kakinuma K, Eguchi T
[PMID: 16568718]J Antibiot (Tokyo). 59 (2006) 44-52

close this sectionData download

Compound nameGenomic
nucleotide
sequence
Nucleotide
sequences of the
coding regions
Translation of the
coding sequences
List of genes/ORFsGBK
Halstoctacosanolide
Genomic nucleotide sequence
109 KB
Nucleotide sequences of the coding regions
103 KB
Translation of the coding sequences
35 KB
List of genes/ORFs
1 KB

 

 
GenBank format
193 KB

close this sectionHistory

  • 2012-03-28[Release]