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Cluster information : Griseorhodin A


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Entry nameGriseorhodin A
PKS TypeTypeII
Starter Unitacetyl-CoA
Chain Length13
Sugar Unitnone
ClassificationRubromycin
ActivityAntibacterial
human telomerase inhibitor
CompositionC25H16O12
Griseorhodin A

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Organism
StrainJP95
Contig
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close this sectionPKS/NRPS Module

KS3..375
CLF12..369
ACP30..77

close this sectionReference

A gene cluster from a marine Streptomyces encoding the biosynthesis of the aromatic spiroketal polyketide griseorhodin A.
Li A, Piel J
[PMID: 12323376]Chem Biol. 9 (2002) 1017-26
Biosynthesis of pentangular polyphenols: deductions from the benastatin and griseorhodin pathways.
Lackner G, Schenk A, Xu Z, Reinhardt K, Yunt ZS, Piel J, Hertweck C
[PMID: 17625850]J Am Chem Soc. 129 (2007) 9306-12
Cleavage of four carbon-carbon bonds during biosynthesis of the griseorhodin a spiroketal pharmacophore.
Yunt Z, Reinhardt K, Li A, Engeser M, Dahse HM, Gutschow M, Bruhn T, Bringmann G, Piel J
[PMID: 19175308]J Am Chem Soc. 131 (2009) 2297-305

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Compound nameGenomic
nucleotide
sequence
Nucleotide
sequences of the
coding regions
Translation of the
coding sequences
List of genes/ORFsGBK
Griseorhodin A
Genomic nucleotide sequence
37 KB
Nucleotide sequences of the coding regions
33 KB
Translation of the coding sequences
13 KB
List of genes/ORFs
5 KB

 

 
GenBank format
78 KB

close this sectionHistory

  • 2013-01-16[Release]