close all open/close all

CDS information : A4793_00050


close this sectionLocation

Organism
StrainNRRL 15009
Entry nameA47934
Contig
Start / Stop / Direction7,541 / 6,312 / - [in whole cluster]
7,541 / 6,312 / - [in contig]
Locationcomplement(6312..7541) [in whole cluster]
complement(6312..7541) [in contig]
TypeCDS
Length1,230 bp (409 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category3.3 modification reduction
Productcytochrome P450
Product (GenBank)StaJ
GenestaJ
oxyC
ORF30
Gene (GenBank)
EC number
Keyword
  • 4th cross-linking
  • AB ring
Note
  • The N-terminal position was modified from original INSDC entry.
Note (GenBank)
  • P450-related oxidase
Reference
ACC
PmId
[12060705] Assembling the glycopeptide antibiotic scaffold: The biosynthesis of A47934 from Streptomyces toyocaensis NRRL15009. (Proc Natl Acad Sci U S A. , 2002)
[17884639] The biosynthesis of teicoplanin-type glycopeptide antibiotics: assignment of p450 mono-oxygenases to side chain cyclizations of glycopeptide a47934. (Chem Biol. , 2007)

close this sectionSequence

selected fasta
>cytochrome P450 [StaJ]
MDEADEVAPVVRPTANYMRRTLCDPHEDMFALRAHGPLIRIEGNASDQMSTDYVWQAMGY
DVVRKILGDHENFTTRLRLTDAQPLSGEGVSVPPELAGQISIYDPPEHTRLRRMLTPEFT
VRRIRRLEPAIEGIIEEHLDALEGAGPPADLQVLFADPVGGETLCELLGVPRDDRNEFIR
RVRQNVDLSRGYKARAADSAAFNRYLMTLITRQRKDPDEGFLGMLVREHGDRITDEELKG
VCTALILGGVESVAGMIGFGVLALLEHPDQRRLLFGSREEADRLVNELLRFLSAVQQPTP
RMAVRDVVVEGQLIKAGEYVLCSILMANRDEGLTSDSHLLDANREPLPHVAFGHGIHHCI
GAAVARAVLRITYQSLWRRFPRLSLAVPAGEVKFRNAFIDSPDRLPVTW
selected fasta
>cytochrome P450 [StaJ]
GTGGATGAGGCGGACGAGGTCGCCCCGGTCGTCCGGCCGACGGCGAACTACATGAGAAGA
ACGCTCTGCGATCCGCACGAGGACATGTTCGCCCTCAGGGCGCATGGCCCGCTGATCCGG
ATCGAGGGCAACGCGTCCGATCAGATGAGCACGGACTACGTCTGGCAGGCCATGGGCTAC
GACGTGGTGCGCAAGATACTCGGCGATCATGAGAACTTCACGACGCGGCTCCGGCTGACC
GATGCGCAACCCCTCAGTGGCGAAGGGGTGTCGGTCCCGCCGGAGCTGGCCGGACAGATC
TCGATCTACGATCCGCCCGAACACACGCGGCTGCGGCGGATGTTGACGCCCGAGTTCACG
GTCCGGCGGATCCGCAGGCTGGAGCCGGCGATCGAGGGCATCATCGAAGAGCACCTCGAT
GCGTTGGAGGGCGCGGGACCGCCTGCGGATCTCCAGGTGCTGTTCGCCGACCCGGTCGGC
GGCGAGACCCTGTGCGAGCTGCTCGGGGTCCCGCGGGACGATCGGAACGAGTTCATCCGC
CGCGTCAGGCAGAACGTCGACCTCAGCCGCGGCTACAAGGCCAGGGCGGCGGACAGCGCG
GCCTTCAACCGATACCTGATGACGCTCATCACCCGGCAGCGGAAGGATCCCGACGAGGGG
TTCCTCGGCATGCTCGTACGTGAGCACGGCGACCGGATCACCGACGAGGAGTTGAAGGGC
GTCTGCACGGCGCTGATCCTCGGCGGCGTCGAGAGCGTCGCCGGGATGATCGGCTTCGGG
GTCCTCGCGCTGCTCGAGCACCCCGACCAGAGGCGGCTGCTCTTCGGTTCCCGCGAGGAG
GCCGACCGCCTGGTGAACGAACTGCTGCGTTTCCTTTCGGCCGTGCAGCAGCCGACTCCG
CGAATGGCCGTCAGGGACGTCGTCGTGGAGGGGCAGTTGATCAAGGCGGGGGAGTACGTC
CTCTGCTCGATTCTCATGGCCAACCGCGACGAGGGGCTGACGTCGGATTCCCATCTCCTC
GACGCGAACCGTGAACCCCTCCCGCATGTCGCCTTCGGGCACGGCATCCATCACTGCATA
GGCGCCGCAGTGGCAAGGGCGGTGCTCCGCATCACCTATCAGTCCCTGTGGCGACGGTTC
CCGCGACTGAGCCTGGCCGTGCCCGCGGGGGAAGTGAAGTTCCGTAACGCGTTCATAGAC
AGCCCGGATCGCTTGCCGGTCACCTGGTAG

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09
show BLAST table
InterPro
Database:interpro:38.0
IPR001128 Cytochrome P450 (Family)
 [283-380]  2.2e-09 PF00067
PF00067   p450
 [3-409]  9e-85 SSF48264
SSF48264   Cytochrome P450
 [8-409]  2.8e-88 G3DSA:1.10.630.10
G3DSA:1.10.630.10   no description
IPR002397 Cytochrome P450, B-class (Family)
 [103-114]  3.3e-42 PR00359 [150-166]  3.3e-42 PR00359 [167-182]  3.3e-42 PR00359 [204-226]  3.3e-42 PR00359 [283-294]  3.3e-42 PR00359 [301-328]  3.3e-42 PR00359 [329-344]  3.3e-42 PR00359 [350-359]  3.3e-42 PR00359 [359-370]  3.3e-42 PR00359
PR00359   BP450
IPR017972 Cytochrome P450, conserved site (Conserved_site)
 [352-361]  PS00086
PS00086   CYTOCHROME_P450
SignalP No significant hit
TMHMM No significant hit