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CDS information : A4793_00070


close this sectionLocation

Organism
StrainNRRL 15009
Entry nameA47934
Contig
Start / Stop / Direction10,273 / 9,077 / - [in whole cluster]
10,273 / 9,077 / - [in contig]
Locationcomplement(9077..10273) [in whole cluster]
complement(9077..10273) [in contig]
TypeCDS
Length1,197 bp (398 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category3.3 modification reduction
Productcytochrome P450
Product (GenBank)StaH
GenestaH
oxyB
ORF28
Gene (GenBank)
EC number
Keyword
  • 1st cross-linking
  • C-O-D ring
Note
Note (GenBank)
  • P450-related oxidase
Reference
ACC
PmId
[12060705] Assembling the glycopeptide antibiotic scaffold: The biosynthesis of A47934 from Streptomyces toyocaensis NRRL15009. (Proc Natl Acad Sci U S A. , 2002)
[17884639] The biosynthesis of teicoplanin-type glycopeptide antibiotics: assignment of p450 mono-oxygenases to side chain cyclizations of glycopeptide a47934. (Chem Biol. , 2007)

close this sectionSequence

selected fasta
>cytochrome P450 [StaH]
MSGDDRPPIHTLRQGFDPADELRAAGELTRVRLGSGADAEHTWLATGHDVVRQVLGDHTR
FSTRRRFDRNDEIGGKGVFRPRELVGNLMDYDPPEHTRLRRLLAPGFTHRKIRRMAPYIE
QIVTERLDEMEREGSPADLIELFADEVPGPVLCELLGVPRDDRAMFLQLCHRHLDASLSG
RRRAAAGEAFSRYLVTMVARERKDPGDGLIGMVVAEHGDTVTDEELRGVCVQMMLAGDDN
ISGMIGLGVLALLRNPEQIAALRGDVPAAERAVDELIRYLTVPYAPTPRTAIEDSTVGDQ
VIKAGETVLCSLPTANRDPALLPDADRLDVTREAVPHVAFGHGVHHCLGAALARLELRIA
YTALWRRFPDLRLADPDGATEFRLSTPAYGISRLMVTW
selected fasta
>cytochrome P450 [StaH]
TTGAGTGGTGACGACCGGCCTCCGATCCACACGCTCCGGCAGGGCTTCGACCCGGCCGAC
GAGCTGCGCGCCGCCGGAGAGCTGACGCGGGTCAGGCTCGGATCCGGAGCGGATGCCGAG
CACACCTGGCTGGCCACCGGGCACGACGTCGTCCGGCAGGTGCTCGGGGACCACACGAGG
TTCAGCACGCGCCGCCGCTTCGACCGGAACGACGAGATCGGCGGGAAGGGCGTCTTCCGG
CCCCGCGAGCTGGTCGGCAACCTGATGGACTACGACCCTCCGGAGCACACCCGGCTACGG
CGCCTGCTGGCCCCGGGGTTCACCCATCGCAAGATACGGCGGATGGCCCCGTACATCGAG
CAGATCGTGACGGAACGCCTCGACGAGATGGAGCGGGAAGGGTCCCCCGCGGATCTGATC
GAGTTGTTCGCCGACGAGGTGCCCGGCCCCGTGCTGTGCGAGCTGCTCGGGGTACCGCGG
GACGACCGCGCCATGTTCCTCCAGCTCTGCCACCGGCATCTCGACGCCTCGCTCAGCGGC
CGGCGGCGGGCGGCCGCGGGCGAGGCGTTCTCCCGCTACCTGGTGACCATGGTCGCCAGG
GAACGGAAGGACCCCGGCGACGGGCTCATCGGCATGGTGGTCGCCGAACACGGCGACACG
GTCACCGATGAGGAGCTGAGGGGCGTCTGCGTACAGATGATGCTGGCCGGAGACGACAAC
ATCTCGGGCATGATCGGCCTGGGCGTGCTGGCGCTGCTGCGGAACCCCGAGCAGATCGCC
GCGCTGCGGGGCGACGTCCCGGCGGCGGAGCGGGCGGTCGACGAGCTGATCCGGTACCTG
ACGGTCCCCTATGCTCCGACGCCCCGGACCGCCATCGAGGACAGCACCGTCGGCGACCAG
GTGATCAAGGCGGGGGAGACGGTCCTCTGCTCTCTCCCGACGGCCAACCGCGACCCCGCC
CTGCTGCCGGACGCGGATCGCCTCGACGTCACCCGGGAGGCCGTCCCCCATGTCGCGTTC
GGGCACGGTGTTCACCATTGTCTGGGAGCCGCTCTCGCCCGCCTCGAACTGCGCATCGCC
TATACCGCGCTGTGGCGACGCTTTCCCGACCTGCGGCTGGCGGATCCCGACGGGGCGACC
GAGTTCCGGCTGAGCACCCCCGCATATGGAATCAGCAGGCTGATGGTCACGTGGTGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09
show BLAST table
InterPro
Database:interpro:38.0
IPR001128 Cytochrome P450 (Family)
 [5-398]  3.99998544139406e-89 SSF48264
SSF48264   Cytochrome_P450
 [210-368]  4.80000000000001e-17 PF00067
PF00067   p450
 [20-398]  5.50000000000008e-96 G3DSA:1.10.630.10
G3DSA:1.10.630.10   Cyt_P450
IPR002397 Cytochrome P450, B-class (Family)
 [91-102]  5.50001754266469e-53 PR00359 [138-154]  5.50001754266469e-53 PR00359 [155-170]  5.50001754266469e-53 PR00359 [192-214]  5.50001754266469e-53 PR00359 [271-282]  5.50001754266469e-53 PR00359 [289-316]  5.50001754266469e-53 PR00359 [317-332]  5.50001754266469e-53 PR00359 [338-347]  5.50001754266469e-53 PR00359 [347-358]  5.50001754266469e-53 PR00359
PR00359   BP450
IPR017972 Cytochrome P450, conserved site (Conserved_site)
 [340-349]  PS00086
PS00086   CYTOCHROME_P450
SignalP No significant hit
TMHMM No significant hit