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CDS information : A4793_00080


close this sectionLocation

Organism
StrainNRRL 15009
Entry nameA47934
Contig
Start / Stop / Direction11,417 / 10,263 / - [in whole cluster]
11,417 / 10,263 / - [in contig]
Locationcomplement(10263..11417) [in whole cluster]
complement(10263..11417) [in contig]
TypeCDS
Length1,155 bp (384 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category3.3 modification reduction
Productcytochrome P450
Product (GenBank)StaG
GenestaG
oxyE
ORF27
Gene (GenBank)
EC number
Keyword
  • 2nd cross-linking
  • F-O-G ring
Note
Note (GenBank)
  • P450-related oxidase
Reference
ACC
PmId
[12060705] Assembling the glycopeptide antibiotic scaffold: The biosynthesis of A47934 from Streptomyces toyocaensis NRRL15009. (Proc Natl Acad Sci U S A. , 2002)
[17884639] The biosynthesis of teicoplanin-type glycopeptide antibiotics: assignment of p450 mono-oxygenases to side chain cyclizations of glycopeptide a47934. (Chem Biol. , 2007)

close this sectionSequence

selected fasta
>cytochrome P450 [StaG]
MALPLPHRRHRLDPVPEFHDLQNEGPLHEYDTEPGMDGRKQWLVTGYHEVRDILADPERF
SSMRPVDDEADRALLPGILQAYDPPDHTRLRRTVAPAYSARRMERLRPRIEEIVEECLDD
LEDVGSPVDFVRYAAWPIPALIACEFLDVPRDDRAELSRMIRESRESRLPRQRTSSGMGV
VNYTQKLAARKRLDPGEGMIGVIVREHGAEVSDEELAGLAEGNLIMAAEQMAAQLAVAVL
LLVTHPDQMALLREHPELVDGATEELLRHASIVEAPAPRVALEDVSVAGRDIRAGDVLTC
SMMAVNRPQGEHFDITRENPKHMAFGYGIHHCLGAPLARLQLRVALPAVLRRFPSLRLAV
PEEDLRFKPGRPAPFAVEELPVEW
selected fasta
>cytochrome P450 [StaG]
ATGGCACTTCCCTTGCCGCACCGGCGGCACCGGCTCGATCCTGTGCCGGAGTTCCACGAC
CTGCAGAACGAGGGGCCGCTGCACGAATACGACACCGAGCCCGGGATGGACGGCCGTAAG
CAGTGGCTGGTCACCGGGTACCACGAGGTTCGGGACATCCTCGCCGATCCCGAGCGGTTC
AGCTCCATGCGGCCGGTCGACGACGAGGCCGACCGGGCCCTGCTGCCGGGAATCCTGCAG
GCGTACGACCCGCCGGACCACACCCGGTTGCGCAGGACCGTGGCCCCGGCCTACTCCGCC
CGGCGGATGGAACGGCTGCGGCCCCGCATCGAGGAGATCGTCGAAGAATGCCTGGACGAC
CTGGAGGACGTGGGGTCGCCGGTCGACTTCGTCAGGTACGCGGCCTGGCCCATCCCGGCG
CTGATCGCCTGTGAGTTCCTCGACGTCCCCCGCGACGACCGGGCCGAGCTGTCGCGGATG
ATCCGGGAGAGCAGGGAGAGCAGGCTCCCTCGGCAGCGGACCTCTTCGGGGATGGGAGTC
GTCAACTACACCCAGAAGCTGGCGGCCCGCAAGCGCCTCGATCCCGGCGAGGGGATGATC
GGTGTCATCGTGCGCGAGCACGGGGCGGAGGTCAGTGACGAGGAACTGGCGGGGCTCGCC
GAGGGCAACCTGATCATGGCCGCCGAGCAGATGGCTGCCCAGCTGGCGGTCGCGGTGCTC
CTGCTGGTGACCCATCCCGACCAGATGGCGTTGCTTCGCGAACATCCCGAGCTCGTCGAC
GGCGCGACCGAGGAGCTGCTGCGGCACGCTTCGATCGTCGAGGCCCCGGCCCCCCGGGTC
GCTCTCGAGGACGTGAGTGTCGCCGGACGTGACATCCGGGCCGGAGACGTCCTGACCTGC
TCCATGATGGCGGTCAACCGTCCGCAGGGCGAACACTTCGACATCACCCGTGAGAACCCG
AAGCACATGGCGTTCGGATACGGCATCCACCACTGTCTCGGGGCACCGCTGGCCAGGCTC
CAGCTACGGGTGGCCCTGCCGGCGGTGCTCCGCCGGTTCCCGTCGCTGCGGCTCGCCGTC
CCCGAGGAGGACCTGCGGTTCAAGCCCGGCCGGCCCGCGCCCTTCGCCGTGGAGGAGCTT
CCCGTTGAGTGGTGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09
show BLAST table
InterPro
Database:interpro:38.0
IPR001128 Cytochrome P450 (Family)
 [8-384]  3.19999999999996e-88 G3DSA:1.10.630.10
G3DSA:1.10.630.10   Cyt_P450
 [256-353]  9.50000000000001e-15 PF00067
PF00067   p450
 [11-384]  4.60000044330866e-79 SSF48264
SSF48264   Cytochrome_P450
IPR002397 Cytochrome P450, B-class (Family)
 [82-93]  1.79999754022375e-29 PR00359 [129-145]  1.79999754022375e-29 PR00359 [146-161]  1.79999754022375e-29 PR00359 [182-204]  1.79999754022375e-29 PR00359 [261-272]  1.79999754022375e-29 PR00359 [323-332]  1.79999754022375e-29 PR00359 [332-343]  1.79999754022375e-29 PR00359
PR00359   BP450
IPR017972 Cytochrome P450, conserved site (Conserved_site)
 [325-334]  PS00086
PS00086   CYTOCHROME_P450
SignalP No significant hit
TMHMM No significant hit