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Ansam_00510 Ansam_00510   last last

CDS information : Ansam_00520


close this sectionLocation

Organism
StrainATCC 31565
Entry nameAnsamitocin
Contig
Start / Stop / Direction94,650 / 93,097 / - [in whole cluster]
11,904 / 10,351 / - [in contig]
Locationcomplement(93097..94650) [in whole cluster]
complement(10351..11904) [in contig]
TypeCDS
Length1,554 bp (517 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category4.1 transcriptional regulator
Productputative LuxR family transcriptional regulator(fragment)
Product (GenBank)transcription activator
Geneasm48
Gene (GenBank)
EC number
Keyword
Note
Note (GenBank)
  • ORF11; member of LuxR family
Reference
ACC
PmId
[12060743] The biosynthetic gene cluster of the maytansinoid antitumor agent ansamitocin from Actinosynnema pretiosum. (Proc Natl Acad Sci U S A. , 2002)
Related Reference
ACC
Q06BL5
NITE
Gelda_00100
PmId
[18214443] The LuxR family members GdmRI and GdmRII are positive regulators of geldanamycin biosynthesis in Streptomyces hygroscopicus 17997. (Arch Microbiol. , 2008)

close this sectionSequence

selected fasta
>putative LuxR family transcriptional regulator(fragment) [transcription activator]
CSPDRVRRAAVQARLAAAEWLVNPSTSARHHTALLAAFRAGRLSVRDSATLVEHLRWAGS
TADSDAVLAGLRADPRAAEEVPVLEHWLAGAYPGAARPGTAPGRDVDSARTRAEQAPRAN
AVLLDVLVAGDGDHVADRAEAVLREVRLARDPGGSGGAAVPALSALLYSDRADVAASWCE
QLLSARAVPLLPVPRAQVLALAAESALRRGDHPRADELAREALTVLPPTAWGVSVGLPLS
TRILALTRMGRCDEAAAVVARPVPNGVFGHRTSVDYLHARGHFLLARGRPRAALGDFLLC
GEQLTRWGLGGGCAPVPWRTAAAEAWLAQGDPDRARALAHEQLGRPGSDSRRARGQALRL
LAATGPVKRRPRLLREAVAVFEAVDDKYELARTLRDLGGAQRALGEHALARRVVRRGWHV
ARMCGAAPLCEELMPTADGLVPAQQASAACGSDTGRLTSSEHRVAALAASGLTNREIAVK
LYVTHSTVEQHLTRVFRKLGIKQREQLPPALSADRSG
selected fasta
>putative LuxR family transcriptional regulator(fragment) [transcription activator]
TGCAGCCCGGACCGGGTGCGCAGGGCGGCCGTGCAGGCGCGGCTGGCGGCGGCCGAGTGG
CTGGTGAACCCGTCGACCTCGGCCAGGCACCACACCGCGCTGCTGGCGGCGTTCCGCGCG
GGCAGGTTGTCGGTGCGCGACAGCGCGACGCTGGTGGAGCACCTGCGCTGGGCCGGGAGC
ACCGCCGACTCGGACGCGGTGCTCGCCGGGCTGCGGGCCGACCCGCGCGCCGCCGAGGAG
GTGCCGGTGCTGGAGCACTGGCTGGCTGGCGCCTACCCCGGTGCGGCCAGGCCGGGGACC
GCGCCGGGGCGGGACGTGGACTCCGCGCGCACCAGGGCGGAGCAGGCGCCGAGGGCGAAC
GCGGTGCTGCTGGACGTGCTGGTGGCCGGGGACGGCGACCACGTGGCCGACCGGGCGGAG
GCGGTGCTGCGGGAGGTGCGGCTGGCGCGGGACCCCGGCGGCTCCGGCGGTGCGGCCGTG
CCTGCGCTGTCCGCGCTGCTGTACTCGGACCGCGCGGACGTGGCCGCCTCCTGGTGCGAG
CAGCTGCTGTCGGCGCGGGCCGTGCCGCTGCTGCCGGTACCGCGCGCGCAGGTGCTGGCG
CTGGCGGCCGAGTCGGCGCTGCGCCGGGGCGACCACCCGAGGGCGGACGAGCTGGCGCGG
GAGGCGCTGACCGTGCTGCCCCCCACCGCGTGGGGGGTGTCGGTGGGGCTGCCGCTGAGC
ACCCGGATCCTGGCGCTGACCAGGATGGGCCGCTGCGACGAGGCGGCGGCCGTGGTGGCG
CGGCCGGTGCCGAACGGGGTGTTCGGGCACCGCACCAGCGTGGACTACCTGCACGCGCGC
GGGCACTTCCTCCTGGCGCGGGGACGGCCGCGCGCGGCGCTGGGCGACTTCCTGCTGTGC
GGGGAGCAGCTGACCCGGTGGGGTCTGGGCGGCGGGTGCGCGCCGGTGCCGTGGCGGACC
GCGGCGGCGGAGGCGTGGCTGGCGCAGGGCGACCCGGACCGGGCGCGGGCGCTGGCGCAC
GAGCAGCTCGGCAGGCCGGGCTCGGACAGCAGGCGGGCGCGCGGGCAGGCGCTGCGGCTG
CTCGCGGCGACCGGCCCGGTGAAGCGGCGCCCGCGGCTGCTGCGGGAGGCGGTGGCGGTG
TTCGAGGCCGTGGACGACAAGTACGAGCTGGCGCGGACCCTGCGCGACCTGGGAGGGGCG
CAGCGGGCGCTGGGCGAGCACGCGCTGGCGCGCCGGGTGGTCCGGCGCGGGTGGCACGTC
GCCCGGATGTGCGGGGCGGCGCCGCTGTGCGAGGAGCTGATGCCCACCGCCGACGGGCTG
GTGCCCGCGCAGCAGGCGTCGGCGGCCTGCGGGTCGGACACGGGCCGGTTGACCAGCTCG
GAGCACCGGGTGGCCGCGCTCGCGGCGTCGGGGCTGACGAACCGGGAGATCGCGGTGAAG
CTGTACGTCACGCACAGCACGGTGGAGCAGCACCTGACGCGGGTGTTCCGCAAGCTCGGG
ATCAAGCAGCGGGAGCAGCTGCCGCCCGCGCTGAGCGCCGACCGGTCGGGGTGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09
show BLAST table
InterPro
Database:interpro:38.0
IPR000792 Transcription regulator LuxR, C-terminal (Domain)
 [457-471]  1.20000117458134e-09 PR00038 [471-487]  1.20000117458134e-09 PR00038 [487-499]  1.20000117458134e-09 PR00038
PR00038   HTHLUXR
 [471-498]  PS00622
PS00622   HTH_LUXR_1
 [454-511]  1.20000117458134e-20 SM00421
SM00421   HTH_LUXR
 [450-517]  PS50043
PS50043   HTH_LUXR_2
 [456-507]  2.2e-11 PF00196
PF00196   GerE
IPR011990 Tetratricopeptide-like helical (Domain)
 [195-251]  1.1e-16 G3DSA:1.25.40.10 [252-465]  1.1e-16 G3DSA:1.25.40.10
G3DSA:1.25.40.10   TPR-like_helical
IPR011991 Winged helix-turn-helix transcription repressor DNA-binding (Domain)
 [466-507]  1.2e-17 G3DSA:1.10.10.10
G3DSA:1.10.10.10   Wing_hlx_DNA_bd
IPR016032 Signal transduction response regulator, C-terminal effector (Domain)
 [435-507]  2.70000183580794e-14 SSF46894
SSF46894   Bipartite_resp_reg_C-effector
SignalP No significant hit
TMHMM No significant hit
Ansam_00510 Ansam_00510   last last