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CDS information : Aran_00120


close this sectionLocation

Organism
StrainTü303
Entry nameAranciamycin
Contig
Start / Stop / Direction17,617 / 16,844 / - [in whole cluster]
17,617 / 16,844 / - [in contig]
Locationcomplement(16844..17617) [in whole cluster]
complement(16844..17617) [in contig]
TypeCDS
Length774 bp (257 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category3.4 other modification
Productputative cyclase
Product (GenBank)cyclase
Gene
Gene (GenBank)
EC number
Keyword
  • 2nd and 3rd ring
Note
Note (GenBank)
  • orf12
Reference
ACC
PmId
[17357167] Cloning and heterologous expression of the aranciamycin biosynthetic gene cluster revealed a new flexible glycosyltransferase. (Chembiochem. , 2007)
Related Reference
ACC
Q9L4U2
NITE
Acla_00250
PmId
[12715874] Studies on a second and third ring cyclization in anthracycline biosynthesis. (J Antibiot (Tokyo). , 2003)
ACC
Q9RN54
NITE
Nogl_00250
PmId
[11683270] The entire nogalamycin biosynthetic gene cluster of Streptomyces nogalater: characterization of a 20-kb DNA region and generation of hybrid structures. (Mol Genet Genomics. , 2001)
[12715874] Studies on a second and third ring cyclization in anthracycline biosynthesis. (J Antibiot (Tokyo). , 2003)
ACC
O68500
NITE
Adria_00160
PmId
[9573189] The Streptomyces peucetius dpsY and dnrX genes govern early and late steps of daunorubicin and doxorubicin biosynthesis. (J Bacteriol. , 1998)
[10419974] The Streptomyces peucetius dpsC gene determines the choice of starter unit in biosynthesis of the daunorubicin polyketide. (J Bacteriol. , 1999)

close this sectionSequence

selected fasta
>putative cyclase [cyclase]
MRIIDLSSPIDADGWEPDPVRHDIMTPAEGARHMSEEMKRHFGLDLDPSELPGGELLSLD
TLTLTSHTGTHVDAPSHYGSTASYGVPRHIDRMPLEWFLRPGMLLDVSDVGTGVIDRDRI
QDAIKRVGRQPEPLDIVLLHTGAAQHAGTPRYFTDFAGLDGPATEYLLDFGVRVIGTDAW
SLDAPFPDMIRRYRESGDPSVLWPAHFAGRRTEYCQIERLAHLEDLPASTGFQVCCFPVK
IRNGGAGWARAVALVDG
selected fasta
>putative cyclase [cyclase]
GTGCGCATCATCGACCTGTCCTCACCGATCGACGCCGACGGATGGGAGCCCGACCCCGTC
CGGCACGACATCATGACGCCCGCCGAGGGCGCCCGTCACATGAGCGAGGAGATGAAACGG
CACTTCGGGCTGGACCTGGACCCGTCCGAACTGCCCGGCGGCGAACTGCTGTCGCTGGAC
ACGCTGACCCTGACCAGCCACACCGGCACCCATGTCGACGCGCCCTCGCACTACGGGTCC
ACCGCCTCGTACGGGGTGCCCCGGCACATCGACCGGATGCCGCTGGAGTGGTTCCTGCGG
CCCGGGATGCTGCTCGACGTCTCCGACGTCGGCACGGGCGTGATCGACCGCGACCGGATC
CAGGACGCGATCAAACGCGTCGGACGCCAGCCCGAGCCCCTGGACATCGTGCTGCTGCAC
ACCGGCGCCGCCCAGCACGCCGGAACCCCCCGCTACTTCACGGACTTCGCCGGTCTCGAC
GGGCCGGCCACCGAGTACCTGCTGGACTTCGGCGTCCGGGTCATCGGCACCGACGCCTGG
AGCCTCGACGCGCCCTTCCCCGACATGATCAGGCGCTACCGGGAGAGCGGCGACCCGTCG
GTCCTGTGGCCGGCGCACTTCGCCGGACGCCGTACGGAGTACTGCCAGATCGAGCGGCTG
GCCCACCTGGAGGACCTGCCTGCGTCGACCGGCTTCCAGGTCTGCTGCTTCCCGGTGAAG
ATCAGGAACGGGGGCGCCGGCTGGGCGCGCGCGGTGGCGCTCGTGGACGGGTGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09
show BLAST table
InterPro
Database:interpro:38.0
IPR007325 Putative cyclase (Family)
 [3-185]  1e-39 PF04199
PF04199   Cyclase
SignalP No significant hit
TMHMM No significant hit