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Asco_00090 Asco_00090   Asco_00110 Asco_00110

CDS information : Asco_00100


close this sectionLocation

Organism
StrainATCC 14891 (=NBRC 13981)
Entry nameAscomycin
Contig
Start / Stop / Direction11,248 / 10,988 / - [in whole cluster]
11,248 / 10,988 / - [in contig]
Locationcomplement(10988..11248) [in whole cluster]
complement(10988..11248) [in contig]
TypeCDS
Length261 bp (86 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category2.1 modification addition of extender units
Productputative acyl carrier protein
Product (GenBank)FkbJ
Gene
Gene (GenBank)fkbJ
EC number
Keyword
  • methoxymalonyl-ACP
Note
Note (GenBank)
  • ACP
Reference
ACC
PmId
[10863099] The FK520 gene cluster of Streptomyces hygroscopicus var. ascomyceticus (ATCC 14891) contains genes for biosynthesis of unusual polyketide extender units. (Gene. , 2000)
Related Reference
ACC
Q8KUG2
PmId
[11996558] Functional expression of genes involved in the biosynthesis of the novel polyketide chain extension unit, methoxymalonyl-acyl carrier protein, and engineered biosynthesis of 2-desmethyl-2-methoxy-6-deoxyerythronolide B. (J Am Chem Soc. , 2002)
ACC
Q9XBU6
PmId
[16983083] Hydroxymalonyl-acyl carrier protein (ACP) and aminomalonyl-ACP are two additional type I polyketide synthase extender units. (Proc Natl Acad Sci U S A. , 2006)

close this sectionSequence

selected fasta
>putative acyl carrier protein [FkbJ]
MTAPVKDDPVAHALVAFLKTKTRSDWPVDRDLFAEGGLTSLFAMELVVYLEKTFDVTIAG
PDLQLANFRTVESMVALVHRLRAVDA
selected fasta
>putative acyl carrier protein [FkbJ]
ATGACCGCACCCGTCAAGGACGACCCCGTCGCGCACGCGTTGGTCGCGTTCCTCAAGACG
AAGACCAGGTCGGACTGGCCCGTGGACCGCGACCTGTTCGCGGAGGGCGGCCTCACGTCG
CTGTTCGCGATGGAACTGGTCGTGTACCTGGAGAAGACGTTCGACGTCACGATCGCCGGC
CCGGACCTCCAGCTCGCGAACTTCCGTACCGTCGAGTCCATGGTCGCACTCGTCCACCGG
CTGCGGGCCGTCGATGCCTGA

close this sectionFeature

BLASTP
Database:UniProtKB:2010_04 		show BLAST table
InterPro
Database:interpro:26.0
IPR006163 Phosphopantetheine-binding (Domain)
[19-78] 7.80000000000001e-05 PF00550
PF00550   PP-binding
IPR009081 Acyl carrier protein-like (Domain)
[6-79] PS50075
PS50075   ACP_DOMAIN
[2-82] 3.3e-12 SSF47336
SSF47336   ACP_like
SignalP
[1-24] 0.115 Signal
Eukaryota   
TMHMM No significant hit
Asco_00090 Asco_00090   Asco_00110 Asco_00110
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