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CDS information : Balhi_00280


close this sectionLocation

Organism
StrainDSM 5908
Entry nameBalhimycin
Contig
Start / Stop / Direction56,501 / 57,913 / + [in whole cluster]
56,501 / 57,913 / + [in contig]
Location56501..57913 [in whole cluster]
56501..57913 [in contig]
TypeCDS
Length1,413 bp (470 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category2.3 modification addition of sugar moiety
Productputative dTDP-4-keto-6-deoxy-D-glucose 2,3-dehydratase
Product (GenBank)putative NDP-hexose 2,3-dehydratase
Gene
Gene (GenBank)dvaA
EC number
Keyword
  • dehydrovancosamine
Note
Note (GenBank)
Reference
ACC
Related Reference
ACC
O52793
NITE
Chlor_00240
PmId
[11035791] Deoxysugars in glycopeptide antibiotics: enzymatic synthesis of TDP-L-epivancosamine in chloroeremomycin biosynthesis. (Proc Natl Acad Sci U S A. , 2000)
[23473392] Structure of EvaA: a paradigm for sugar 2,3-dehydratases. (Biochemistry. , 2013)

close this sectionSequence

selected fasta
>putative dTDP-4-keto-6-deoxy-D-glucose 2,3-dehydratase [putative NDP-hexose 2,3-dehydratase]
MLPDLVPPVVVRPRDGRDHADRIALSAATTDGVHMRTEDVRAWIAERREANDFHVERVPF
RDLDQWSFEEVTGNLVHHSGRFFTIEGLHVIEHDGPNGDGPYREWQQPVIKQPEVGILGI
LGKEFGGVLHFLMQAKMEPGNPNLVQLSPTVQATRSNYTKAHGGTNVKLIEYFAPPDPEH
VIVDVLQAEQGSWFFRKSNRNMIVETVDDVPLWDDFCWLTLGQIAELMHEDETINMNARS
VLSCLPYHDAAPGARFSDVQLLSWFTNERSRHDVRARRIPLADVCGWKQGDEAIEHEDGR
YFRVLAVAVRGSNRERISWTQPLLESVDLGVVAFLVREIGGVPHVLVHARADGGFLDTVE
LAPTVQCTPQNYAHLPAENRPPFLDVVLNAPESRIRYEAIHSEEGGRFLNVRARYLAIEA
DDTVEPPPGYTWVTPAQLTALTRHGHYVNVEARTLLACLNAATAQPRGGA
selected fasta
>putative dTDP-4-keto-6-deoxy-D-glucose 2,3-dehydratase [putative NDP-hexose 2,3-dehydratase]
ATGCTGCCTGACCTCGTTCCCCCGGTCGTGGTGCGCCCCCGCGACGGCCGCGACCACGCG
GACCGCATCGCGTTGTCGGCGGCGACCACCGACGGGGTGCACATGCGGACCGAGGACGTC
CGCGCCTGGATCGCCGAACGCCGTGAGGCCAACGACTTCCACGTCGAACGCGTCCCGTTC
CGGGACCTCGACCAGTGGTCGTTCGAGGAGGTGACCGGCAACCTCGTGCACCACAGCGGA
CGGTTCTTCACCATCGAGGGCCTGCACGTGATCGAGCACGACGGCCCGAACGGCGACGGC
CCCTACCGCGAGTGGCAGCAACCGGTCATCAAGCAGCCCGAAGTCGGCATCCTCGGCATC
CTGGGCAAGGAGTTCGGCGGCGTCCTGCACTTCCTGATGCAGGCCAAGATGGAGCCGGGG
AACCCCAATCTGGTGCAGCTCTCGCCGACCGTGCAGGCCACCCGCAGCAACTACACCAAG
GCGCACGGCGGCACGAACGTCAAGCTGATCGAGTACTTCGCCCCGCCCGACCCCGAGCAC
GTCATCGTCGACGTTCTCCAGGCCGAGCAAGGCTCGTGGTTCTTCCGCAAGTCCAATCGC
AACATGATCGTCGAGACCGTCGACGACGTGCCGCTGTGGGACGACTTCTGCTGGCTCACC
CTCGGCCAGATCGCGGAGCTGATGCACGAGGACGAGACGATCAACATGAACGCCAGGAGC
GTGTTGTCGTGCCTGCCTTACCACGACGCGGCTCCCGGCGCGCGGTTCTCCGACGTCCAG
CTCCTGTCGTGGTTCACGAACGAGCGTTCGCGGCACGACGTGCGTGCCCGCCGCATCCCG
CTCGCGGACGTGTGCGGCTGGAAGCAGGGCGACGAAGCGATCGAGCACGAGGACGGCCGT
TATTTCCGGGTCCTCGCGGTCGCCGTGCGGGGGAGCAACCGCGAGCGGATCAGCTGGACC
CAGCCGCTGCTCGAATCCGTCGACCTGGGTGTCGTCGCGTTCCTCGTGCGCGAGATCGGC
GGTGTGCCCCACGTTCTGGTGCACGCCCGCGCCGACGGTGGTTTCCTGGACACGGTCGAG
CTGGCACCGACCGTCCAGTGCACTCCCCAAAACTACGCGCACCTGCCCGCGGAGAACCGC
CCGCCCTTCCTCGACGTCGTCCTCAACGCTCCGGAGTCGCGCATTCGTTACGAGGCAATA
CATTCCGAAGAGGGCGGGCGCTTCCTCAACGTCCGGGCGCGCTACCTCGCGATCGAAGCG
GACGACACGGTCGAGCCCCCTCCCGGCTACACCTGGGTCACGCCGGCCCAGCTCACCGCG
CTCACCCGGCACGGGCACTACGTCAACGTCGAGGCCCGCACGCTGCTCGCCTGCCTCAAC
GCCGCGACGGCCCAGCCTCGAGGCGGTGCCTGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09
show BLAST table
InterPro
Database:interpro:38.0
IPR005212 NDP-hexose 2,3-dehydratase (Domain)
 [36-245]  4.40000000000003e-82 PF03559 [258-459]  1.29999999999998e-83 PF03559
PF03559   Hexose_dehydrat
SignalP No significant hit
TMHMM No significant hit