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CDS information : Calm_00070


close this sectionLocation

Organism
StrainNRRL 15839
Entry nameCalicheamicin
Contig
Start / Stop / Direction7,595 / 6,006 / - [in whole cluster]
7,595 / 6,006 / - [in contig]
Locationcomplement(6006..7595) [in whole cluster]
complement(6006..7595) [in contig]
TypeCDS
Length1,590 bp (529 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category4.3 transport
Productputative drug resistance transporter
Product (GenBank)CalT1
Gene
Gene (GenBank)calT1
EC number
Keyword
Note
Note (GenBank)
Reference
ACC
PmId
[12183629] The calicheamicin gene cluster and its iterative type I enediyne PKS. (Science. , 2002)
Related Reference
ACC
Q9ZGB6
NITE
Lando_00240
PmId
[18537830] Coordination of export and glycosylation of landomycins in Streptomyces cyanogenus S136. (FEMS Microbiol Lett. , 2008)

close this sectionSequence

selected fasta
>putative drug resistance transporter [CalT1]
MTATMPAETPKVSAGRMSRREVLQALSGLMVGMFVSILASTVVANALPRIIADLDGSQTV
YTWIVTTELLAMTATVPLWGKMADLYSKKLLIQLSLGLFAVGSLIAGLTPNVEVLLISRI
VQGVGAGGMTALATIVMAAMIPPRELGRYAGIFGAVFGVGTIAGPLIGGVLVDTSWLGWR
WCFLIGVPFTLLSIVLLQRTLHLPVTRRKVRIDWLGALLITSGVSTLLIWSSLAGNSFAW
ASGWTALMVVGGLALLGLAVWVESRAEEPIVPLDIFRNRTVSLTTIASVLVGVAMFGGTV
FLSQYFQIALGKSPTVAGLMSLPMIFGLLVSSTVAGQLITKYGRWKRFLVAGAVVMTVGM
LLLSTIDADTGVPLLSVYMAVLGVGVGMLMQNLVLVAQNDVPAHELGAATSVLTFFRSMG
GTIGVSALGAVLANRVATLSAEKLGPLAGGATAGGGHAVPDLSALPEPVLRIIQDVYGTA
TAELFLIGAPFALLAVVVVLFIREKPLHTLSGEERRAREEAAAGMPGAH
selected fasta
>putative drug resistance transporter [CalT1]
ATGACCGCCACCATGCCCGCCGAGACCCCCAAGGTCAGCGCCGGCCGCATGTCCCGCCGA
GAGGTGCTCCAGGCACTCTCCGGCCTGATGGTCGGCATGTTCGTGTCGATCCTCGCCTCC
ACGGTCGTGGCGAACGCGCTGCCGCGCATCATCGCCGACCTGGACGGCTCGCAGACCGTC
TACACGTGGATCGTCACCACCGAGCTGCTGGCCATGACGGCGACCGTGCCGCTGTGGGGC
AAGATGGCCGACCTCTACAGCAAGAAGCTGCTCATCCAGCTCTCCCTCGGGCTCTTCGCG
GTCGGTTCGCTGATCGCCGGGCTGACCCCGAACGTCGAGGTGCTGCTGATCAGCCGCATC
GTGCAGGGTGTCGGCGCGGGCGGCATGACCGCCCTGGCCACCATCGTGATGGCGGCGATG
ATCCCGCCCCGCGAGCTGGGTCGCTACGCCGGCATCTTCGGCGCCGTGTTCGGCGTCGGC
ACCATCGCCGGCCCGCTCATCGGCGGCGTACTGGTGGACACCTCCTGGCTCGGCTGGCGG
TGGTGCTTCCTGATCGGGGTGCCGTTCACCCTGCTCTCGATCGTCCTGCTCCAGCGCACC
CTGCACCTGCCGGTGACCCGCCGCAAGGTGCGCATCGACTGGCTCGGCGCGCTGCTCATC
ACCTCGGGCGTCTCCACCCTGCTGATCTGGTCGTCGCTGGCCGGCAACTCCTTCGCCTGG
GCGTCCGGCTGGACCGCCCTGATGGTCGTCGGCGGGCTCGCCCTGCTCGGGCTGGCGGTC
TGGGTCGAGTCGCGCGCGGAGGAGCCGATCGTGCCGCTGGACATCTTCCGCAACCGGACG
GTCTCGTTGACCACCATCGCCAGCGTGCTGGTCGGCGTGGCGATGTTCGGCGGCACCGTG
TTCCTGTCCCAGTACTTCCAGATCGCGCTGGGCAAGTCGCCGACGGTGGCGGGGCTGATG
AGCCTGCCGATGATCTTCGGCCTGCTGGTCTCGTCGACCGTCGCCGGTCAGCTGATCACG
AAGTACGGCCGCTGGAAGCGGTTCCTGGTGGCCGGCGCCGTCGTGATGACCGTCGGCATG
CTGCTGCTGAGCACCATCGACGCCGACACCGGCGTGCCGCTGCTCAGCGTCTACATGGCG
GTGCTCGGCGTCGGCGTCGGCATGCTGATGCAGAACCTCGTGCTCGTGGCGCAGAACGAC
GTGCCCGCGCACGAGCTGGGCGCGGCCACCTCCGTGCTGACCTTCTTCCGCAGCATGGGC
GGGACGATCGGGGTGAGCGCGCTCGGCGCGGTGCTGGCCAACCGGGTCGCGACGCTGAGC
GCGGAGAAGCTCGGCCCGTTGGCCGGCGGCGCCACCGCCGGGGGCGGGCACGCCGTGCCC
GACCTGTCCGCGCTGCCCGAGCCGGTGCTGCGGATCATCCAGGACGTGTACGGGACCGCC
ACCGCCGAGCTGTTCCTCATCGGCGCCCCGTTCGCGCTGCTCGCCGTGGTGGTCGTGCTG
TTCATCCGGGAGAAGCCGCTGCACACCCTCAGCGGTGAGGAGCGGCGCGCCCGGGAGGAG
GCGGCGGCCGGAATGCCCGGCGCGCACTGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09
show BLAST table
InterPro
Database:interpro:38.0
IPR001411 Tetracycline resistance protein TetB/drug resistance transporter (Family)
 [28-52]  3.70000251046782e-10 PR01036 [119-139]  3.70000251046782e-10 PR01036 [149-173]  3.70000251046782e-10 PR01036 [415-434]  3.70000251046782e-10 PR01036
PR01036   TCRTETB
IPR006311 Twin-arginine translocation pathway, signal sequence (Conserved_site)
 [1-46]  PS51318
PS51318   TAT
IPR011701 Major facilitator superfamily (Family)
 [29-424]  1.09999999999999e-46 PF07690
PF07690   MFS_1
IPR016196 Major facilitator superfamily domain, general substrate transporter (Domain)
 [1-520]  2.1000026783403e-75 SSF103473
SSF103473   MFS_gen_substrate_transporter
IPR020846 Major facilitator superfamily domain (Domain)
 [25-507]  PS50850
PS50850   MFS
SignalP No significant hit
TMHMM
 [22-44]  Transmembrane (i-o) [59-81]  Transmembrane (o-i) [94-116]  Transmembrane (i-o) [120-142]  Transmembrane (o-i) [149-171]  Transmembrane (i-o) [176-198]  Transmembrane (o-i) [211-233]  Transmembrane (i-o) [238-260]  Transmembrane (o-i) [281-303]  Transmembrane (i-o) [318-340]  Transmembrane (o-i) [347-364]  Transmembrane (i-o) [374-396]  Transmembrane (o-i) [409-431]  Transmembrane (i-o) [480-502]  Transmembrane (o-i)
Transmembrane 14