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CDS information : Chalc_00230


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Organism
StrainNRRL 2737
Entry nameChalcomycin
Contig
Start / Stop / Direction43,022 / 54,388 / + [in whole cluster]
43,022 / 54,388 / + [in contig]
Location43022..54388 [in whole cluster]
43022..54388 [in contig]
TypeCDS
Length11,367 bp (3,788 aa)
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close this sectionAnnotation

Category1.1 PKS
Productpolyketide synthase
Product (GenBank)polyketide synthase subunit
Gene
Gene (GenBank)chmGIII
EC number
Keyword
Note
Note (GenBank)
  • modules 4-5 KS/AT/KR/ACP/KS/AT/DH/ER/KR/ACP
Reference
ACC
PmId
[15561847] Chalcomycin biosynthesis gene cluster from Streptomyces bikiniensis: novel features of an unusual ketolide produced through expression of the chm polyketide synthase in Streptomyces fradiae. (Antimicrob Agents Chemother. , 2004)

close this sectionPKS/NRPS Module

4 methylmalonyl-CoA
5 methylmalonyl-CoA
KS40..418
AT579..896
kr1160..1330
ACP1445..1515
KS1543..1919
AT2071..2387
DH2436..2635
ER3007..3312
KR3322..3503
ACP3619..3689

close this sectionSequence

selected fasta
>polyketide synthase [polyketide synthase subunit]
MSSTSPATNEEKLRDYLRRAMTDLHEAREQIRRTESARHEPIAIVGMGCRLPGGVSSPEG
LWDLVASGVDAVSPFPTDRGWDVGGLFDPEPGVPGRSYVREGGFLHEAGEFDAGFFGISP
REALAMDPQQRLLLETSWEALERAGIDPHTLRGSRTGVYAGVMYHDYGSTATVSVASDDE
TAGFLGTGTSGSVASGRISYVLGLEGPAVTVDTACSSSLVALHLAVRALRSGECDLALAG
GVTVMAEPGVFVEFSRQRGLAADGRCKAFAAAADGTGWAEGVGVLAVERLSDAVRHGRRV
LAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALADARLGVADVDVVEGHGTGTRLGDPI
EAQALLATYGQRDAGRALRLGSLKSNVGHTQAAAGVAGVIKMVMAMRHGVLPKTLHVDEP
TAEVDWSAGAVSLLREQEAWPEVGRLRRAAVSSFGVSGTNAHVVVEEAPASEAPVAGEPV
EPVEPGAVGLLPVVPVVVSGRSAGAVAELASRLNESVRSDRLVDVGLSSVVSRSVFEHRS
VVLAEDSAELHTGLVAVGTGVPSPGVVSGVASVEGGRSVFVFPGQGTQWAGMALGLWAES
AVFAESMARCEAAFAGLVDWRLADVLGDRSALERVDVVQPASFAVMVSLAELWRSLGVVP
DAVVGHSQGEIAAAVVAGGLSLEDGARVVVLRARLIGRELAGHGGMASVALPVAVVEERL
AAWAGRLGVAVVNAPSATVVAGDVDAVAEFVTACEVEGVRARVLPVDYASHSAHVEELRA
ELEQILAGIDPVAGETPLYSTVEAGVVDTASMDAGYWFRNLRRPVRFQETVERLLADGFR
VFVECGAHPVLTGAVQETAESTGRQVCAVGSLRRDEGGLRRFLTSAAEAFVQGVEVSWPV
LFDGTGARTVDLPTYPFQRRRYWLESRPPAAVVPSGVQDGLSYEVVWKSLPVRESSRLDG
RWLLVVPETLDADGTRIAHDLQHALTTHGATVHTLALDPSAAHFDGLFDGILQEETDVTG
IFSLLGLASGPHPDHGEVELAGAASLTLMRQAQRDGFRAPVWAVTRGAVSVVPGEVPETA
GAQLWALGRVAGLELPDRWGGLIDLPADADARTAGLAVRALAAGIADGEDQLAVRPSGAY
GRRLVRATARRGRKDWRPQGTVLLAGHLDAVGEPLARWLLTGGADHVVLADPALTELPAT
LADLAQTVTTAAAPDLADRAVLAALVTEYVPATVVVVPPAAELAPLASISPADLAAAVTA
KSATAAHFDALLDGPHAPELVLISSVAGIWGGVRQGAYAVGAAHLDALAARRRARGLSAA
SVAWTPWAGSVTADGSAAESLRQYGIAPLEPQAALAELDRALNQQLHGGGGDAAVADIDW
ERFLASFTSVRPSVLFDELPEVRRLREAEAAAMADQAAARTGAPGGTELARSLRAKSLNA
QRTALLELVTAHVAAVLGESVPEAIDRSRAFKDIGFTSMTAMELRNRLKEATGLALPASL
VFDHPHPGALADHLREELLGEDGAAGADSAAEEPSATSPTVQDEPIAIIGMACRLPGDVG
TPDELWELLETGRDAMSDLPVNRGWDVAGLYDPDPDAAGRSYVREGGFLHDAGEFDAEFF
GISPREALAMDPQQRIVLELAWESFERAGLDPAGRRGSRTGVFMGTNGQHYMPLLQNGND
SFDGYLGTGNSASVMSGRISYTLGLEGPALTVDTACSSSLVALHLAVRALRNGECDLALA
GGATVMSTPEVLVEFSRQRAVSADGRCKAFSASADGFGPAEGAGVLLVERLSDAVRHGRR
VLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALADARLGVADVDVVEGHGTGTRLGDP
IEAQALLATYGQRDAGRPLRLGSLKSNVGHTQAAAGVAGVIKMVMAMRHGVLPKTLHVDE
VSPHVDWSAGAVSLLTEQEPWPEVGRPRRAAVSSFGLSGTNAHVVVEEAPVGEAGQAAGD
ARLAVVPVVVSGRSAGAVAELASRLNESIRSDRLVDVGLSSVVSRSVFEHRSVLLAGDSG
ELHTGLVAVGTGVPSPGVVSGVASVGGGRSVFVFPGQGTQWAGMALGLWAESSVFAESMA
RCEAAFEGLVDWSLADVLGDGSALERVDVVQPASFAVMVSLAELWRSLGVVPDAVVGHSQ
GEIAAAVVAGGLSLEDGARVVVLRARLIGRELAGRGGMASVALPVAVVEERLAGWAGRLG
VAVVNGPSATVVAGDVDAVAEFVTACEVEGVRARVLPVDYASHSAHVEDLKAELEEVLAG
IGPVTGGIPFYSTSEAAQIDTAGLDAGYWFGNLRRPVRFQETVERLLADGFRVFVECGAH
PVLTGAVQETAESTGRQVCAVGSLRRDEGGLRRFLTSAAEAFVQGVGVFWPALFDGTGAR
IVDLPTYPFQRRHYWYNDPARRTGDATSFGMAQAGHPLLDAGTELPESGEHLYTARLAAD
SHPWLLEHTLLGAPLLPGAAFVDLVLWAGGEVGCDLIEELTLTSPLLLSDSAALQLRLVV
GTADAEGRRTITVHSRPDGDPRTTRTPAASSETSPDAESDTEIRRDTSAWTKHAQATVAP
APDVPPSGVDAEGDAVRPAVEWSVAATESDAFQAEDFYASFAAHGYGYGPLFQGVRSGRQ
DGTDVYAEVALDHDRLPSAEQFGLHPALLDAAFQTMRLGSFFPDDGQARVPYTFRGIRLY
APGAARLRVRVSAVGADAVRVECADERGRLVCEIDALVVSTVSPDQLRPAGQDATQDMLH
RIEWPVLSPPTGSATSPAPPRWIVVGGEDEGLGLGGLRLDGPRLDGPGLAEALSEAGMGT
ERHRNLADALSAVRTPVDTAGSAAAAGTTSLIAVPVPQSPTMDAGAVRHAVHRALELVQG
WVAADEAAEEGGSDGAAADRRLVLVTSGAVSTGDADPLRDPVAAAVWGLIKSAQSEQPGR
IVLVDLDEGAVDGAALAAAISTGEPQLALRDGDVHVPRLAPLSVRDSQTLLPPAGTRAWH
LVGAGTGTLSDLALVPAQTDTVALAPGQVRIAVRAAGLNFRDTLIALGMYPGEGVMGAEG
AGVITEVGPDVVSLAVGDRVLGMWTDGFGPYVVADHRMVAPMPRDWSYAEAASVPAVFLS
AYYGLRHLAGLRAGQSVLVHAAAGGVGMAAVQLARHFGAEVFGTAGTAKWDALRAQGLDD
RHIAGSRTLDFADRFLDATEGRGVDVVLNSLAGDFVDASLRLLPRGGRFVELGKADVRDA
AQVAADRPGTVYRAFELMEAGPELIGRMLNELLELFESGALRLLPVTPYDIRRAPDAFRT
LSQAGHVGKLVLTMPPAFEPHGTVLITGGTGNLGGTLARHLVTEHGVRHLLLAGRRGPEA
EGAAELVRELHDLGASVTVAACDVADRAALRKLLGGIPPERPLTGVVHAAGVLDDGVVTS
LTPDRVDGVLRPKVDAALNLHEAALDPELGLDITAFVLFSSVAALLGGSGQGSYAAANGF
LDGLAQYRRGRSLPALSLGWGLAGSGRMTSHLDSRALLRRMARGGVLPLSPAESMALFDA
AQGFDEALQVPARFHTAALGADGNVPPLFNGLIRGGTAHAEARRRTVGASPAGGPAGGEP
VNLADRLSGLTEDEQRALLLDTVRTHAALVLGHTGTDGIQADRAFKDLGFDSLTAVEMRN
RLTAATGLHLAATLVFDHPAPADLAEHLRSRLVPEGTDVPPLLAELGRLETAFKKLTTAD
LASVVPDDIARDEIAVRLAALGSLWNGLHGNGLSGDAAQKHGDSIVEDIDSADDDEIFAF
LDESFGDS
selected fasta
>polyketide synthase [polyketide synthase subunit]
ATGTCTTCCACATCGCCCGCCACCAACGAAGAGAAGCTCCGCGACTACCTCCGCCGCGCC
ATGACCGACCTGCACGAGGCCCGCGAGCAGATCCGCCGGACCGAGTCGGCCAGGCACGAG
CCGATCGCGATCGTGGGGATGGGGTGCCGTCTGCCGGGTGGGGTGTCGTCGCCGGAGGGG
TTGTGGGATCTGGTGGCGTCGGGGGTGGATGCGGTTTCTCCGTTCCCCACGGATCGGGGT
TGGGATGTGGGGGGTCTGTTCGATCCGGAGCCGGGGGTGCCGGGGCGTTCGTATGTGCGT
GAGGGCGGGTTCCTTCATGAGGCGGGGGAGTTCGACGCGGGGTTCTTCGGTATCTCTCCG
CGTGAGGCGTTGGCGATGGATCCGCAGCAGCGGTTGCTGTTGGAGACGTCGTGGGAGGCG
TTGGAGCGGGCGGGCATCGATCCGCACACGCTCCGCGGCTCACGGACCGGCGTCTACGCC
GGAGTGATGTACCACGACTACGGCAGCACCGCGACCGTCTCCGTCGCCTCCGACGACGAG
ACCGCCGGATTCCTCGGCACGGGGACGTCCGGGAGTGTGGCTTCGGGTCGTATCTCGTAT
GTGCTGGGGCTGGAGGGGCCGGCGGTGACGGTGGACACGGCGTGTTCGTCGTCGTTGGTG
GCGCTGCATCTGGCGGTGCGGGCGCTGCGGAGTGGTGAGTGTGACCTTGCTCTTGCGGGT
GGGGTGACGGTGATGGCGGAGCCGGGTGTGTTCGTGGAGTTCTCGCGGCAGCGGGGGTTG
GCTGCGGACGGGCGGTGCAAGGCGTTCGCGGCTGCTGCCGATGGCACGGGCTGGGCCGAG
GGTGTGGGCGTGCTGGCGGTGGAGCGGTTGTCGGATGCGGTGCGTCACGGGCGCCGGGTC
CTGGCGGTCGTGCGTGGTTCCGCGGTCAACCAGGACGGTGCGAGCAATGGGTTGACGGCT
CCGAACGGTCCGTCGCAGCAGCGGGTGATTCGTCAGGCGTTGGCGGATGCGCGGTTGGGT
GTGGCTGATGTGGATGTGGTGGAGGGGCATGGGACGGGGACGCGTCTGGGTGATCCGATC
GAGGCGCAGGCGTTGTTGGCGACGTATGGGCAGCGGGATGCGGGTCGGGCTTTGCGGCTT
GGTTCGCTGAAGTCGAACGTGGGGCATACGCAGGCGGCTGCCGGTGTGGCGGGCGTGATC
AAGATGGTCATGGCGATGCGGCACGGTGTCCTGCCGAAGACGCTGCACGTGGATGAGCCG
ACGGCGGAGGTGGACTGGTCGGCGGGCGCGGTGTCCCTGCTGAGGGAGCAGGAGGCGTGG
CCTGAGGTGGGGCGTCTGCGTAGGGCTGCGGTGTCTTCGTTCGGTGTGAGTGGGACGAAC
GCGCATGTGGTGGTGGAGGAGGCACCTGCTTCGGAGGCGCCGGTCGCGGGGGAGCCGGTG
GAGCCGGTGGAGCCGGGGGCTGTGGGGCTTCTTCCGGTGGTGCCGGTGGTGGTGTCGGGT
CGTTCTGCGGGTGCGGTGGCGGAGCTGGCCTCCCGCTTGAACGAGTCGGTTCGTTCGGAT
CGGTTGGTGGATGTGGGGTTGTCGTCGGTGGTGTCGCGGTCGGTGTTCGAGCACCGGTCC
GTGGTTCTGGCGGAGGACTCTGCCGAGCTGCATACCGGTCTGGTTGCTGTCGGGACTGGG
GTGCCGTCGCCTGGCGTGGTGTCGGGTGTGGCGTCGGTCGAGGGTGGCCGGTCGGTGTTC
GTGTTCCCTGGTCAGGGGACGCAGTGGGCGGGGATGGCGCTCGGGTTGTGGGCGGAGTCG
GCGGTGTTCGCGGAGTCGATGGCGCGGTGTGAGGCGGCGTTCGCCGGGTTGGTGGACTGG
CGTCTGGCGGATGTGCTGGGTGACAGGTCTGCGTTGGAGCGGGTCGATGTGGTGCAGCCG
GCGTCGTTCGCGGTGATGGTGTCGCTGGCCGAGCTGTGGCGGTCGCTGGGTGTGGTGCCC
GATGCGGTGGTGGGGCATTCGCAGGGGGAGATCGCTGCTGCGGTGGTGGCGGGTGGTCTC
TCGCTGGAGGACGGCGCGCGTGTGGTGGTGTTGCGTGCGCGGTTGATAGGCCGTGAGCTG
GCCGGGCACGGTGGGATGGCGTCGGTGGCGCTGCCGGTCGCGGTGGTGGAGGAGCGTCTG
GCGGCGTGGGCGGGGCGTCTGGGTGTGGCGGTGGTCAACGCACCCTCCGCCACGGTCGTC
GCGGGTGATGTGGACGCGGTGGCGGAGTTTGTGACCGCGTGCGAGGTGGAGGGGGTTCGG
GCGCGTGTTCTGCCGGTGGACTACGCCTCGCACTCGGCGCACGTGGAGGAGCTGAGGGCC
GAGCTTGAACAGATTCTGGCCGGCATCGACCCGGTGGCCGGTGAGACCCCCCTGTACTCC
ACGGTGGAGGCGGGTGTCGTGGATACGGCGTCGATGGATGCGGGGTACTGGTTCAGGAAT
CTGCGTCGGCCGGTTCGTTTCCAGGAGACGGTCGAGCGGTTGCTGGCGGATGGTTTCCGG
GTGTTCGTGGAGTGCGGCGCGCATCCGGTGCTGACGGGGGCGGTGCAGGAGACCGCGGAA
TCCACCGGTCGCCAGGTGTGTGCGGTCGGATCCCTGCGTCGTGACGAGGGTGGTCTGCGA
CGCTTCCTGACCTCTGCGGCGGAGGCGTTCGTCCAGGGGGTGGAGGTGTCCTGGCCGGTG
CTGTTCGATGGCACCGGCGCCCGCACGGTCGACCTGCCCACCTACCCCTTCCAGCGTCGG
CGTTACTGGCTGGAGTCACGTCCTCCTGCGGCGGTTGTTCCGTCGGGGGTCCAGGACGGA
TTGTCGTATGAGGTGGTGTGGAAGAGCCTGCCGGTACGGGAGTCGTCGCGTCTTGACGGC
CGGTGGCTGCTCGTCGTGCCCGAAACCCTGGACGCCGACGGCACGCGGATCGCCCACGAC
CTCCAGCACGCCCTCACCACCCACGGCGCCACCGTGCACACTCTTGCTCTTGACCCCAGC
GCGGCGCACTTCGACGGTCTCTTTGACGGGATACTCCAGGAAGAAACAGATGTCACGGGC
ATCTTCTCTCTCCTCGGACTGGCATCGGGCCCGCACCCGGATCACGGCGAGGTGGAGCTC
GCGGGAGCCGCGTCGCTGACGTTGATGCGCCAAGCCCAGCGAGACGGCTTCCGTGCTCCG
GTGTGGGCGGTGACGCGGGGTGCGGTGTCCGTGGTGCCTGGTGAGGTGCCGGAGACCGCG
GGTGCGCAACTGTGGGCGCTCGGCCGGGTCGCCGGTCTCGAACTCCCCGACCGTTGGGGT
GGTCTGATCGATCTCCCGGCGGATGCCGATGCGCGTACGGCGGGGCTTGCGGTGCGGGCC
CTGGCCGCCGGGATCGCCGATGGTGAGGACCAGCTGGCGGTGCGCCCCTCAGGTGCCTAC
GGCCGGCGCCTCGTACGAGCCACCGCGCGCCGGGGACGGAAGGACTGGCGCCCGCAGGGT
ACGGTGCTGCTCGCCGGGCACCTCGACGCCGTCGGTGAACCACTGGCCCGATGGCTGCTC
ACCGGCGGCGCGGACCACGTCGTCCTTGCGGATCCCGCCCTGACCGAACTCCCGGCCACC
CTCGCGGATCTGGCCCAGACCGTGACGACCGCTGCGGCACCCGACCTTGCCGACCGTGCA
GTCCTCGCCGCCCTGGTCACCGAGTACGTACCCGCCACCGTGGTCGTCGTTCCGCCCGCG
GCGGAGCTCGCTCCGCTGGCGAGTATCAGCCCGGCCGACCTCGCGGCGGCCGTCACCGCC
AAGTCCGCGACCGCGGCGCACTTCGACGCGCTGCTCGACGGACCCCACGCACCGGAGCTG
GTGCTGATCTCCTCGGTCGCGGGGATCTGGGGTGGTGTCCGGCAGGGTGCGTACGCCGTC
GGTGCCGCTCACCTCGATGCCCTGGCCGCCCGCCGCAGGGCCCGCGGTCTGTCGGCGGCC
TCCGTCGCGTGGACGCCCTGGGCGGGTTCCGTCACCGCGGACGGCTCCGCCGCCGAGTCG
CTGCGGCAGTACGGCATCGCTCCGCTGGAGCCGCAGGCGGCGCTCGCGGAGCTGGACCGG
GCGCTGAACCAGCAGCTGCACGGCGGCGGGGGCGACGCGGCGGTGGCCGACATCGACTGG
GAGCGGTTCCTCGCGTCGTTCACCTCCGTACGTCCCAGCGTTCTCTTCGACGAGCTGCCC
GAGGTACGCCGTCTCCGCGAGGCGGAGGCGGCGGCCATGGCGGACCAGGCCGCCGCCCGG
ACGGGAGCGCCCGGCGGAACGGAGCTGGCGCGCTCTCTGCGGGCCAAGTCCCTGAACGCC
CAGCGAACTGCGCTCCTGGAATTGGTCACTGCCCACGTGGCGGCCGTGCTGGGAGAGAGC
GTTCCCGAGGCGATCGACCGGAGCCGGGCGTTCAAGGACATCGGCTTCACCTCCATGACC
GCGATGGAACTGCGCAACCGGCTCAAGGAGGCCACCGGGCTCGCCCTTCCTGCCTCCCTC
GTCTTCGACCACCCCCACCCCGGCGCACTCGCCGACCACCTGCGCGAGGAACTCCTGGGC
GAGGACGGTGCGGCGGGCGCCGACTCCGCGGCGGAGGAACCGAGCGCTACCTCTCCGACG
GTCCAGGACGAGCCGATCGCCATCATCGGCATGGCCTGCCGCCTCCCTGGTGACGTCGGA
ACACCCGACGAACTCTGGGAGCTGCTGGAAACCGGCCGCGACGCGATGTCGGACCTGCCC
GTCAACCGCGGGTGGGACGTGGCGGGGCTCTACGACCCGGATCCAGACGCGGCGGGGCGT
TCCTACGTCCGGGAGGGCGGGTTCCTCCACGACGCGGGGGAGTTCGACGCGGAGTTCTTC
GGCATCTCGCCGCGTGAGGCGCTGGCGATGGACCCGCAGCAGCGCATCGTCCTCGAACTC
GCCTGGGAATCGTTCGAACGTGCGGGCCTGGACCCGGCCGGCCGCCGCGGCAGCCGTACC
GGCGTGTTCATGGGAACCAACGGCCAGCACTACATGCCGCTGCTGCAGAACGGCAACGAC
AGCTTCGACGGCTACCTCGGCACCGGGAACTCGGCCAGTGTCATGTCGGGCCGCATCTCG
TACACCCTCGGCTTGGAGGGGCCGGCGCTGACGGTGGACACGGCGTGTTCGTCGTCGCTG
GTCGCGCTGCATCTGGCGGTGCGGGCGCTGCGCAACGGTGAGTGCGACCTCGCCCTCGCC
GGCGGCGCGACCGTGATGTCGACGCCGGAAGTCCTGGTGGAGTTCTCCCGGCAGCGTGCA
GTCTCCGCAGACGGTCGCTGCAAGGCGTTCTCCGCCTCGGCCGACGGCTTCGGACCGGCC
GAGGGTGCGGGCGTGTTGCTCGTCGAGCGGTTGTCGGATGCGGTGCGTCATGGGCGTCGG
GTGTTGGCGGTCGTGCGTGGTTCGGCGGTGAATCAGGACGGTGCGAGTAATGGGTTGACG
GCTCCGAACGGTCCGTCGCAGCAGCGGGTGATTCGTCAGGCGTTGGCGGATGCGCGGTTG
GGTGTGGCTGATGTGGATGTGGTGGAGGGGCATGGGACGGGGACGCGTCTGGGTGATCCG
ATCGAGGCGCAGGCGTTGTTGGCGACGTATGGGCAGCGGGATGCGGGTCGGCCGTTGCGG
CTTGGTTCGTTGAAGTCGAACGTGGGGCATACGCAGGCGGCTGCCGGTGTGGCGGGCGTG
ATCAAGATGGTCATGGCGATGCGGCACGGTGTCCTGCCGAAGACGCTGCACGTCGATGAG
GTCTCTCCGCACGTCGACTGGTCGGCGGGTGCGGTGTCCCTGCTGACGGAGCAGGAGCCG
TGGCCGGAGGTGGGGCGCCCTCGCAGGGCTGCGGTCTCTTCGTTCGGGCTCAGCGGGACG
AATGCGCATGTGGTGGTCGAGGAGGCGCCGGTCGGGGAGGCGGGGCAGGCCGCCGGGGAT
GCTCGGTTGGCTGTGGTGCCGGTGGTGGTGTCGGGCCGGTCTGCGGGTGCGGTTGCTGAA
CTGGCCTCCCGCTTGAACGAGTCGATTCGTTCGGATCGGTTGGTGGATGTGGGGTTGTCG
TCGGTGGTGTCGCGGTCGGTGTTCGAGCACCGGTCCGTGCTACTGGCGGGGGACTCTGGC
GAGCTGCATACCGGTCTGGTTGCTGTCGGGACTGGTGTGCCGTCGCCTGGTGTGGTGTCG
GGTGTGGCGTCGGTCGGGGGTGGCCGGTCGGTGTTCGTGTTCCCTGGTCAGGGGACGCAG
TGGGCGGGGATGGCGCTCGGGTTGTGGGCGGAGTCGTCGGTGTTCGCGGAGTCGATGGCG
CGGTGTGAGGCGGCGTTCGAGGGGTTGGTGGACTGGAGTCTGGCGGATGTGCTGGGTGAC
GGGTCCGCGTTGGAGCGGGTCGATGTGGTGCAGCCGGCGTCGTTCGCGGTGATGGTGTCG
CTTGCTGAGCTGTGGCGGTCGTTGGGTGTGGTGCCGGATGCGGTGGTGGGGCATTCGCAG
GGGGAGATCGCTGCTGCGGTGGTGGCGGGTGGTCTGTCGTTGGAAGACGGGGCGCGTGTG
GTGGTGTTGCGTGCGCGGTTGATCGGCCGTGAGCTGGCCGGGCGCGGTGGGATGGCGTCG
GTGGCGCTGCCGGTCGCGGTGGTGGAGGAGCGTCTGGCGGGGTGGGCGGGGCGTCTGGGT
GTGGCGGTGGTCAACGGACCGTCCGCCACGGTCGTCGCGGGTGATGTGGATGCGGTGGCG
GAGTTTGTGACCGCGTGCGAGGTGGAGGGGGTTCGGGCGCGTGTTCTGCCGGTGGACTAC
GCCTCGCACTCGGCGCACGTGGAGGACCTGAAGGCCGAGCTTGAAGAGGTGCTGGCCGGC
ATCGGCCCGGTGACCGGTGGGATCCCGTTCTATTCGACGTCCGAAGCCGCGCAGATCGAC
ACGGCTGGTCTGGACGCGGGGTACTGGTTCGGGAATCTGCGTCGGCCGGTGCGGTTCCAG
GAGACGGTCGAGCGGTTGTTGGCGGATGGTTTCCGGGTGTTCGTGGAGTGTGGTGCGCAT
CCGGTGCTGACGGGGGCGGTGCAGGAGACCGCGGAATCCACCGGTCGCCAGGTGTGTGCG
GTCGGATCCCTGCGTCGTGACGAGGGAGGTCTGCGCCGCTTCCTCACCTCTGCGGCGGAG
GCGTTCGTCCAGGGGGTCGGGGTGTTCTGGCCGGCACTGTTCGACGGCACCGGCGCCCGT
ATCGTCGACCTGCCCACCTACCCCTTCCAACGACGGCACTACTGGTACAACGACCCTGCC
CGCCGCACGGGCGATGCCACCTCCTTCGGTATGGCGCAGGCCGGTCATCCCTTGCTCGAT
GCCGGTACGGAGCTCCCTGAATCAGGCGAGCACCTCTACACCGCTCGGCTCGCCGCCGAC
TCGCATCCTTGGCTGCTGGAACACACCCTGCTGGGTGCGCCGTTGCTGCCCGGTGCGGCG
TTCGTCGACCTCGTCCTGTGGGCCGGCGGGGAGGTCGGATGCGACCTGATCGAAGAGCTG
ACGCTGACCTCGCCGCTGCTGTTGTCCGACAGCGCTGCCCTTCAACTGCGGCTGGTCGTG
GGCACGGCGGACGCCGAGGGACGTCGTACGATCACCGTCCACTCGCGGCCGGACGGAGAC
CCGCGTACGACGCGCACACCTGCGGCATCGTCCGAGACCAGCCCGGACGCGGAGTCGGAC
ACGGAGATCCGTAGGGACACGTCCGCCTGGACGAAGCACGCTCAGGCGACGGTCGCCCCC
GCCCCTGACGTCCCCCCTTCCGGGGTGGACGCGGAAGGGGACGCCGTTCGCCCCGCAGTG
GAATGGAGCGTGGCGGCGACGGAGTCGGATGCCTTCCAGGCCGAGGACTTCTACGCGTCC
TTCGCCGCACACGGCTATGGCTACGGCCCGCTGTTCCAGGGCGTACGGTCAGGCCGTCAG
GACGGGACCGACGTCTACGCCGAAGTCGCCCTGGATCACGACCGCTTGCCGTCTGCCGAG
CAGTTCGGCCTGCACCCCGCGCTGCTCGACGCGGCGTTCCAGACGATGCGTCTGGGATCG
TTCTTCCCCGACGACGGACAGGCACGTGTGCCGTACACCTTCCGGGGGATTCGTCTCTAC
GCCCCGGGAGCCGCGCGCCTGCGGGTCCGTGTCTCGGCGGTCGGGGCCGATGCCGTACGC
GTGGAGTGCGCCGATGAGCGGGGGCGGCTCGTCTGTGAGATCGACGCCCTCGTCGTCAGC
ACGGTCTCCCCGGACCAGTTGCGGCCGGCCGGACAGGACGCGACCCAGGACATGCTGCAC
CGGATCGAGTGGCCCGTCCTCTCCCCGCCGACCGGCAGCGCCACCTCCCCTGCTCCGCCC
CGCTGGATCGTGGTCGGGGGCGAGGACGAGGGCCTCGGGCTCGGGGGCCTTCGACTCGAC
GGTCCGAGGCTTGACGGTCCCGGGCTTGCGGAAGCGCTGTCCGAAGCCGGTATGGGGACC
GAGCGTCACCGGAACCTGGCCGACGCGCTGTCGGCCGTACGGACGCCGGTGGACACGGCA
GGCTCCGCTGCCGCCGCCGGCACGACCTCCCTCATAGCCGTCCCCGTACCGCAGTCGCCC
ACCATGGACGCCGGTGCCGTGCGCCACGCCGTCCACCGAGCCCTGGAGCTGGTGCAGGGC
TGGGTGGCGGCGGACGAGGCGGCGGAAGAGGGCGGGAGCGACGGTGCCGCGGCCGACCGG
CGGCTGGTGCTGGTCACGAGCGGAGCGGTGTCCACGGGTGACGCCGACCCGCTGCGCGAC
CCGGTGGCCGCGGCCGTCTGGGGTCTGATCAAGTCCGCCCAGTCGGAGCAGCCCGGCCGC
ATCGTCCTCGTTGACCTCGACGAGGGAGCCGTGGACGGGGCGGCCTTGGCAGCCGCGATC
TCGACCGGCGAACCACAACTCGCCCTGCGCGACGGCGATGTGCACGTGCCCAGGCTGGCA
CCCCTGTCCGTGCGGGACTCGCAGACGCTGCTGCCGCCCGCCGGTACGCGCGCCTGGCAT
CTGGTCGGCGCCGGCACCGGAACCCTTTCGGACCTCGCGCTCGTACCGGCGCAGACCGAC
ACCGTCGCGCTCGCACCTGGGCAGGTGCGGATCGCGGTGCGAGCCGCCGGACTCAACTTC
CGGGACACGCTCATCGCGCTCGGTATGTATCCGGGCGAGGGCGTGATGGGCGCCGAGGGC
GCCGGAGTGATCACCGAGGTCGGCCCGGACGTGGTGAGCCTCGCCGTCGGGGACCGCGTC
CTGGGCATGTGGACCGACGGGTTCGGGCCGTACGTCGTGGCCGACCACCGCATGGTGGCC
CCGATGCCGCGCGACTGGTCCTACGCGGAGGCCGCTTCGGTACCCGCCGTCTTCCTCAGT
GCCTACTACGGACTCAGGCACCTGGCCGGTCTGCGCGCCGGCCAGTCGGTGCTGGTGCAC
GCGGCGGCGGGCGGTGTGGGCATGGCTGCCGTCCAACTCGCCCGGCACTTCGGGGCCGAG
GTCTTCGGCACGGCCGGCACGGCCAAATGGGACGCACTGCGGGCACAGGGCCTGGACGAC
CGGCACATCGCCGGTTCACGGACGCTGGACTTCGCGGACCGGTTTCTCGACGCGACCGAG
GGGCGCGGCGTGGACGTCGTCCTGAACTCGCTGGCGGGCGACTTCGTCGACGCCTCCCTG
CGACTGCTGCCGCGCGGAGGGCGGTTCGTGGAACTGGGCAAGGCGGACGTACGCGACGCC
GCGCAGGTCGCCGCCGACCGGCCGGGAACCGTCTACCGGGCCTTCGAGCTGATGGAGGCC
GGGCCGGAGCTGATCGGCCGCATGCTGAACGAACTGCTGGAACTGTTCGAGTCCGGGGCG
CTGCGCCTGCTGCCCGTCACCCCGTACGACATCCGGCGGGCACCCGACGCCTTCCGCACG
CTCAGCCAGGCCGGTCACGTCGGCAAACTGGTCCTGACGATGCCACCGGCCTTCGAACCC
CACGGCACGGTCCTGATCACCGGCGGCACCGGGAACCTGGGCGGAACACTCGCCCGCCAT
CTCGTGACCGAACACGGAGTGCGCCACCTGCTCCTGGCCGGACGTAGGGGGCCCGAGGCC
GAAGGCGCCGCCGAACTCGTACGGGAACTGCACGACCTGGGCGCCTCCGTCACGGTCGCC
GCCTGTGACGTGGCCGACCGAGCGGCGCTCCGGAAACTCCTCGGCGGCATACCGCCGGAG
CGCCCGCTCACCGGAGTCGTCCACGCGGCGGGCGTTCTCGACGACGGCGTGGTCACGTCA
TTGACCCCGGACAGGGTCGACGGCGTCCTGCGGCCCAAGGTGGATGCCGCTCTCAACCTC
CACGAAGCGGCCCTCGATCCCGAACTCGGTCTCGACATCACCGCGTTCGTCCTGTTCTCG
TCCGTCGCTGCCCTGCTCGGCGGCTCGGGTCAGGGAAGCTACGCCGCCGCCAACGGCTTC
CTCGACGGACTCGCCCAGTACCGGCGTGGCCGCTCGCTGCCCGCGCTCTCCCTCGGCTGG
GGCCTGGCCGGGAGCGGCCGGATGACATCCCACCTGGACAGCCGGGCCCTGCTCCGGCGC
ATGGCCAGGGGCGGTGTCCTGCCGCTGTCCCCGGCGGAGAGCATGGCACTGTTCGACGCG
GCCCAGGGCTTCGACGAGGCGCTCCAGGTGCCGGCGCGCTTCCACACCGCCGCACTGGGC
GCCGACGGCAACGTCCCGCCGCTCTTCAACGGACTGATCCGGGGCGGGACGGCGCATGCC
GAGGCCCGGCGCAGGACGGTCGGCGCGTCGCCCGCGGGTGGTCCTGCCGGAGGCGAGCCG
GTGAACCTCGCCGACCGGCTGTCCGGACTGACGGAGGACGAACAGCGGGCGCTGCTCCTC
GACACGGTGCGCACGCACGCGGCTCTCGTCCTGGGCCACACGGGCACGGACGGCATCCAG
GCCGACCGGGCGTTCAAGGACCTGGGATTCGACTCGCTGACGGCCGTCGAGATGCGCAAC
CGGCTCACCGCCGCCACGGGGCTGCACCTCGCGGCGACGCTGGTCTTCGACCACCCCGCT
CCGGCGGACCTCGCCGAGCACCTCCGCTCTCGACTCGTCCCCGAGGGGACGGACGTACCG
CCGCTCCTCGCGGAACTCGGTCGGCTCGAAACGGCGTTCAAGAAGCTGACCACCGCGGAC
CTCGCCTCGGTCGTGCCCGACGACATCGCCCGCGACGAGATCGCCGTACGTCTCGCCGCC
CTCGGTTCCCTGTGGAACGGGCTCCATGGCAACGGCCTCAGCGGAGACGCGGCGCAGAAG
CACGGCGACTCGATCGTCGAGGACATCGACTCCGCCGACGACGACGAGATCTTCGCCTTC
CTCGACGAGAGCTTCGGCGACTCCTGA
[4] KS40..418
[4] AT579..896
[4] methylmalonyl-CoA768..772
[4] kr1160..1330
[4] ACP1445..1515
[5] KS1543..1919
[5] AT2071..2387
[5] methylmalonyl-CoA2260..2264
[5] DH2436..2635
[5] ER3007..3312
[5] KR3322..3503
[5] ACP3619..3689
[4] KS118..1254
[4] AT1735..2688
[4] methylmalonyl-CoA2302..2316
[4] kr3478..3990
[4] ACP4333..4545
[5] KS4627..5757
[5] AT6211..7161
[5] methylmalonyl-CoA6778..6792
[5] DH7306..7905
[5] ER9019..9936
[5] KR9964..10509
[5] ACP10855..11067

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09
show BLAST table
InterPro
Database:interpro:38.0
IPR001227 Acyl transferase domain (Domain)
 [573-699]  G3DSA:3.40.366.10 [768-885]  G3DSA:3.40.366.10 [2067-2191]  G3DSA:3.40.366.10 [2260-2377]  G3DSA:3.40.366.10
G3DSA:3.40.366.10   Ac_transferase_reg
IPR002198 Short-chain dehydrogenase/reductase SDR (Family)
 [3322-3490]  2.19999999999997e-59 PF00106
PF00106   adh_short
IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site (Conserved_site)
 [3134-3155]  PS01162
PS01162   QOR_ZETA_CRYSTAL
IPR006162 Phosphopantetheine attachment site (PTM)
 [3647-3662]  PS00012
PS00012   PHOSPHOPANTETHEINE
IPR009081 Acyl carrier protein-like (Domain)
 [1449-1514]  2.8e-10 PF00550 [3622-3688]  3.7e-10 PF00550
PF00550   PP-binding
 [1438-1560]  7.19999557654549e-25 SSF47336 [3610-3696]  5.10001002358244e-22 SSF47336
SSF47336   ACP_like
 [1442-1518]  2.89999999999999e-42 G3DSA:1.10.1200.10 [3619-3692]  2.89999999999999e-42 G3DSA:1.10.1200.10
G3DSA:1.10.1200.10   ACP_like
 [1445-1515]  PS50075 [3619-3689]  PS50075
PS50075   ACP_DOMAIN
IPR011032 GroES-like (Domain)
 [2993-3141]  1.20000117458134e-32 SSF50129
SSF50129   GroES_like
IPR013149 Alcohol dehydrogenase, C-terminal (Domain)
 [3145-3236]  4.2e-17 PF00107
PF00107   ADH_zinc_N
IPR013154 Alcohol dehydrogenase GroES-like (Domain)
 [3026-3084]  4.5e-08 PF08240
PF08240   ADH_N
IPR013968 Polyketide synthase, KR (Domain)
 [1160-1329]  1.9e-27 PF08659
PF08659   KR
IPR014030 Beta-ketoacyl synthase, N-terminal (Domain)
 [40-293]  7.99999999999993e-100 PF00109 [1543-1794]  7.20000000000003e-98 PF00109
PF00109   ketoacyl-synt
IPR014031 Beta-ketoacyl synthase, C-terminal (Domain)
 [301-418]  1.09999999999999e-46 PF02801 [1802-1919]  1.70000000000001e-47 PF02801
PF02801   Ketoacyl-synt_C
IPR014043 Acyl transferase (Domain)
 [579-896]  5.30000000000001e-102 PF00698 [2071-2387]  9.69999999999989e-103 PF00698
PF00698   Acyl_transf_1
IPR015083 Polyketide synthase, docking (Domain)
 [8-32]  2.4e-10 PF08990
PF08990   Docking
IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase (Domain)
 [577-877]  4.89996723796399e-65 SSF52151 [2069-2369]  1.20000117458134e-64 SSF52151
SSF52151   Acyl_Trfase/lysoPlipase
IPR016036 Malonyl-CoA ACP transacylase, ACP-binding (Domain)
 [702-767]  1.60000240695997e-17 SSF55048 [2194-2259]  4.30000170645867e-18 SSF55048
SSF55048   Malonyl_transacylase_ACP-bd
IPR016038 Thiolase-like, subgroup (Domain)
 [42-305]  G3DSA:3.40.47.10 [306-470]  3.30000000000002e-126 G3DSA:3.40.47.10 [1546-1806]  G3DSA:3.40.47.10 [1807-1970]  3.30000000000002e-126 G3DSA:3.40.47.10
G3DSA:3.40.47.10   Thiolase-like_subgr
IPR016039 Thiolase-like (Domain)
 [32-470]  2.19999900980707e-102 SSF53901 [1536-1917]  2.89997807423186e-103 SSF53901
SSF53901   Thiolase-like
IPR016040 NAD(P)-binding domain (Domain)
 [1161-1336]  3.09999999999998e-45 G3DSA:3.40.50.720 [3097-3285]  1.29999999999998e-48 G3DSA:3.40.50.720 [3323-3532]  3.09999999999998e-45 G3DSA:3.40.50.720
G3DSA:3.40.50.720   NAD(P)-bd
IPR018201 Beta-ketoacyl synthase, active site (Active_site)
 [206-222]  PS00606 [1707-1723]  PS00606
PS00606   B_KETOACYL_SYNTHASE
IPR020801 Polyketide synthase, acyl transferase domain (Domain)
 [581-876]  1.3000049540733e-114 SM00827 [2073-2368]  2.1000026783403e-114 SM00827
SM00827   PKS_AT
IPR020806 Polyketide synthase, phosphopantetheine-binding domain (Domain)
 [1446-1518]  2.10000267834031e-31 SM00823 [3620-3692]  1e-30 SM00823
SM00823   PKS_PP
IPR020807 Polyketide synthase, dehydratase domain (Domain)
 [2436-2635]  1.90000694315261e-65 SM00826
SM00826   PKS_DH
IPR020841 Polyketide synthase, beta-ketoacyl synthase domain (Domain)
 [42-470]  SM00825 [1546-1971]  SM00825
SM00825   PKS_KS
IPR020842 Polyketide synthase/Fatty acid synthase, KR (Domain)
 [1160-1330]  4.19999771339581e-12 SM00822 [3322-3503]  1.60000240695997e-54 SM00822
SM00822   PKS_KR
IPR020843 Polyketide synthase, enoylreductase (Domain)
 [3007-3312]  SM00829
SM00829   PKS_ER
SignalP No significant hit
TMHMM No significant hit