close all open/close all

CDS information : Chalc_00340


close this sectionLocation

Organism
StrainNRRL 2737
Entry nameChalcomycin
Contig
Start / Stop / Direction75,081 / 73,651 / - [in whole cluster]
75,081 / 73,651 / - [in contig]
Locationcomplement(73651..75081) [in whole cluster]
complement(73651..75081) [in contig]
TypeCDS
Length1,431 bp (476 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category5.1 general function
Productputative xanthine permease
Product (GenBank)putative permease
Gene
Gene (GenBank)ORF9
EC number
Keyword
Note
  • It is supposed that this ORF is not involved in chalcomycin biosynthesis.
Note (GenBank)
  • similar to SC6214, SC6212 from Streptomyces coelicolor; SAV2016, SAV1508, Streptomyces avermitilis, xanthine/uracil permease homology family member
Reference
ACC
PmId
[15561847] Chalcomycin biosynthesis gene cluster from Streptomyces bikiniensis: novel features of an unusual ketolide produced through expression of the chm polyketide synthase in Streptomyces fradiae. (Antimicrob Agents Chemother. , 2004)
Related Reference
ACC
P42086
PmId
[9098051] Xanthine metabolism in Bacillus subtilis: characterization of the xpt-pbuX operon and evidence for purine- and nitrogen-controlled expression of genes involved in xanthine salvage and catabolism. (J Bacteriol. , 1997)

close this sectionSequence

selected fasta
>putative xanthine permease [putative permease]
MPESRPAPEPTKTEDGTDARPDTPARPGDTHPVDQMLPPLKLFSAGLQHVAAMYAGVVAP
PLVVGIGVGLSTADIAFLMSASLFTSGIATLLQTLGFWKVGARLPFVNGVSFAGVAPMLA
IAKAEGPDDALPVIYGAVIVAGVFGFLLAPFFCKLIRFFPPVVTGTVITLIGVSLLPVAF
NWAQGGNAQAPDYGSLTYIGLATATLLITVVLRRVLTGFLKQISILLGLVAGTLLSLPLG
VADFSAVGDADVIGLPTPFHFGAPQFAAAAIISMCIVMLVSMTESTADVLALGEIVERPA
DEKTLAAALRADGLGTALSPLFNGFAASAFAQNVGLVAITKVRSRFVVAAAGGILLLLGL
CPLLASVVALIPQPVLGGVGIALFGTVAASGIQTLAGAALERGDNVLIVAISLGAGIIPI
AAPDFYHAFPEGARIVLDSGISTGCVVAVLLNLAFNHLGRRTDPAPETLPAPAAHH
selected fasta
>putative xanthine permease [putative permease]
ATGCCGGAATCCCGCCCCGCCCCGGAACCGACGAAGACCGAGGACGGAACCGACGCTCGT
CCCGACACCCCCGCAAGACCGGGCGACACCCATCCGGTCGACCAGATGCTGCCCCCGCTG
AAGCTCTTCAGCGCCGGTCTGCAGCACGTCGCCGCCATGTACGCCGGCGTCGTCGCGCCG
CCGCTGGTCGTCGGCATCGGCGTCGGCCTGTCCACCGCGGACATCGCGTTCCTCATGAGC
GCCAGCCTGTTCACCTCGGGCATCGCCACGCTCCTGCAGACGCTCGGCTTCTGGAAGGTC
GGAGCACGGCTCCCGTTCGTCAACGGCGTCTCCTTCGCCGGCGTCGCACCGATGCTCGCG
ATAGCGAAGGCCGAAGGCCCCGACGACGCGCTGCCCGTCATCTACGGCGCCGTGATCGTC
GCCGGCGTCTTCGGATTCCTCCTCGCCCCCTTCTTCTGCAAACTGATCCGCTTCTTCCCG
CCCGTGGTCACGGGCACGGTCATCACCCTCATCGGTGTCTCCCTGCTGCCCGTCGCGTTC
AACTGGGCCCAGGGCGGCAACGCGCAGGCACCGGACTACGGCAGCCTCACGTACATCGGC
CTCGCCACCGCCACCCTGCTGATCACCGTGGTCCTGCGCCGCGTCCTGACGGGCTTCCTC
AAGCAGATCTCCATCCTGCTGGGCCTCGTCGCCGGCACGCTCCTCTCGCTGCCGCTGGGC
GTCGCCGACTTCAGCGCCGTAGGCGACGCCGACGTCATCGGACTCCCCACCCCGTTCCAC
TTCGGCGCTCCGCAGTTCGCGGCCGCGGCGATCATCTCCATGTGCATCGTGATGCTCGTG
TCGATGACCGAGTCCACCGCCGACGTCCTCGCCCTCGGTGAGATCGTCGAGCGGCCGGCC
GACGAGAAGACCCTGGCCGCCGCGCTCCGCGCCGACGGCCTCGGCACCGCCCTCAGCCCG
CTCTTCAACGGCTTCGCCGCCAGCGCCTTCGCCCAGAACGTCGGCCTCGTCGCGATCACC
AAGGTCCGCAGCCGCTTCGTCGTAGCCGCGGCCGGCGGCATCCTCCTCCTGCTCGGCCTC
TGCCCGCTGCTCGCCTCCGTCGTCGCGCTCATCCCCCAGCCCGTCCTCGGCGGAGTGGGC
ATCGCCCTCTTCGGCACCGTCGCCGCCAGCGGCATCCAGACCCTCGCCGGAGCCGCCCTC
GAACGCGGCGACAACGTCCTCATCGTCGCCATCTCCCTGGGCGCCGGCATCATCCCCATC
GCCGCCCCGGACTTCTACCACGCCTTCCCCGAAGGCGCCCGCATCGTCCTCGACTCAGGC
ATCAGCACCGGATGTGTGGTCGCCGTCCTCCTCAACCTCGCCTTCAACCACCTCGGCCGC
AGGACCGACCCCGCTCCGGAGACGCTGCCCGCGCCTGCCGCACACCACTGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09
show BLAST table
InterPro
Database:interpro:38.0
IPR006042 Xanthine/uracil permease (Family)
 [38-453]  2.90000000000003e-108 TIGR00801
TIGR00801   Ncs2
 [371-391]  PS01116
PS01116   XANTH_URACIL_PERMASE
IPR006043 Xanthine/uracil/vitamin C permease (Family)
 [41-423]  1.29999999999998e-95 PF00860
PF00860   Xan_ur_permease
IPR017588 Xanthine permease (Family)
 [46-456]  TIGR03173
TIGR03173   PbuX
SignalP No significant hit
TMHMM
 [46-68]  Transmembrane (o-i) [75-97]  Transmembrane (i-o) [131-153]  Transmembrane (o-i) [158-180]  Transmembrane (i-o) [195-217]  Transmembrane (o-i) [224-246]  Transmembrane (i-o) [261-283]  Transmembrane (o-i) [346-368]  Transmembrane (i-o) [378-400]  Transmembrane (o-i) [407-429]  Transmembrane (i-o) [433-455]  Transmembrane (o-i)
Transmembrane 11