close all open/close all

CDS information : Chlor_00130


close this sectionLocation

Organism
StrainA82846UV37B
Entry nameChloroeremomycin
Contig
Start / Stop / Direction38,065 / 39,288 / + [in whole cluster]
3,821 / 5,044 / + [in contig]
Location38065..39288 [in whole cluster]
3821..5044 [in contig]
TypeCDS
Length1,224 bp (407 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category2.3 modification addition of sugar moiety
Productglycosyltransferase
Product (GenBank)PCZA361.20
GenegtfB
ORF12
Gene (GenBank)
EC number2.4.1.310
Keyword
  • D-glucose
  • Hpg4
Note
Note (GenBank)
Reference
ACC
PmId
[9545426] Sequencing and analysis of genes involved in the biosynthesis of a vancomycin group antibiotic. (Chem Biol. , 1998)
[9115410] Production of hybrid glycopeptide antibiotics in vitro and in Streptomyces toyocaensis. (Chem Biol. , 1997)
[11294642] Tandem action of glycosyltransferases in the maturation of vancomycin and teicoplanin aglycones: novel glycopeptides. (Biochemistry. , 2001)
[11470430] Structure of the UDP-glucosyltransferase GtfB that modifies the heptapeptide aglycone in the biosynthesis of vancomycin group antibiotics. (Structure. , 2001)
[19549605] Chimeric glycosyltransferases for the generation of hybrid glycopeptides. (Chem Biol. , 2009)

close this sectionSequence

selected fasta
>glycosyltransferase [PCZA361.20]
MRVLLATCGSRGDTEPLVALAVRVRDLGADVRMCAPPDCAERLAEVGVPHVPVGPSARAP
IQRAKPLTAEDVRRFTTEAIATQFDEIPAAAEGCAAVVTTGLLAAAIGVRSVAEKLGIPY
FYAFHCPSYVPSPYYPPPPLGEPSTQDTIDIPAQWERNNQSAYQRYGGLLNSHRDAIGLP
PVEDIFTFGYTDHPWVAADPVLAPLQPTDLDAVQTGAWILPDERPLSPELAAFLDAGPPP
VYLGFGSLGAPADAVRVAIDAIRAHGRRVILSRGWADLVLPDDGADCFAIGEVNHQVLFG
RVAAVIHHGGAGTTHVAARAGAPQILLPQMADQPYYAGRVAELGVGVAHDGPIPTFDSLS
AALATALTPETHARATAVAGTIRTDGAAVAARLLLDAVSREKPTVSA
selected fasta
>glycosyltransferase [PCZA361.20]
ATGCGTGTGCTGTTGGCGACGTGTGGATCGCGCGGAGATACCGAACCGCTGGTGGCACTG
GCGGTTCGGGTGCGGGACCTCGGCGCGGATGTGCGGATGTGCGCACCGCCGGACTGCGCG
GAGCGGCTGGCCGAGGTAGGTGTGCCGCATGTGCCCGTCGGCCCGTCGGCGCGCGCGCCG
ATCCAGCGAGCGAAACCGTTGACGGCCGAGGACGTGCGCCGGTTCACGACCGAGGCGATC
GCTACGCAGTTCGACGAGATCCCGGCGGCGGCCGAGGGGTGTGCCGCGGTGGTGACCACC
GGCCTGCTGGCCGCCGCGATCGGCGTGCGGTCGGTGGCCGAGAAGCTGGGCATCCCCTAC
TTCTATGCCTTCCACTGTCCGAGTTATGTGCCGTCGCCGTACTATCCGCCGCCGCCCCTC
GGCGAACCGTCCACACAGGACACGATCGACATTCCGGCGCAGTGGGAGCGGAACAACCAG
AGCGCCTACCAGCGGTACGGCGGCCTGCTCAACAGCCACCGGGACGCGATCGGCCTGCCA
CCGGTGGAGGACATCTTCACCTTCGGCTACACCGATCACCCCTGGGTGGCGGCGGATCCG
GTGCTGGCCCCGCTGCAGCCGACAGACCTCGACGCCGTGCAGACCGGCGCGTGGATCCTG
CCCGACGAACGGCCGCTTTCCCCGGAGCTGGCGGCGTTTCTGGACGCCGGCCCACCGCCG
GTGTACCTGGGGTTCGGCAGCCTGGGCGCACCTGCTGACGCGGTCCGGGTGGCCATCGAC
GCGATCCGTGCCCATGGCCGCCGGGTGATCCTTTCCCGTGGCTGGGCCGATTTGGTCCTG
CCCGACGACGGTGCCGACTGCTTCGCGATCGGCGAAGTGAACCATCAGGTGCTGTTCGGC
CGAGTCGCCGCCGTCATCCACCACGGCGGCGCGGGCACGACGCACGTGGCCGCGCGGGCA
GGTGCACCCCAGATCCTGTTGCCCCAGATGGCGGACCAGCCGTACTACGCCGGCCGGGTG
GCCGAACTGGGTGTTGGTGTGGCACATGATGGTCCAATTCCGACCTTCGATTCCTTGTCG
GCCGCGCTTGCCACGGCTCTGACCCCCGAAACCCACGCGCGAGCGACGGCCGTGGCAGGC
ACGATCCGCACCGACGGGGCAGCGGTGGCCGCGCGGTTGCTGCTCGACGCGGTCAGTCGG
GAAAAGCCGACTGTTTCCGCGTAA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09
show BLAST table
InterPro
Database:interpro:38.0
IPR004276 Glycosyl transferase, family 28 (Domain)
 [3-134]  2.2e-30 PF03033
PF03033   Glyco_transf_28
SignalP No significant hit
TMHMM No significant hit