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first first   Chro_00020 Chro_00020

CDS information : Chro_00010


close this sectionLocation

Organism
StrainATCC 13273 (=NBRC 3746)
Entry nameChromomycin
Contig
Start / Stop / Direction784 / 8 / - [in whole cluster]
784 / 8 / - [in contig]
Locationcomplement(8..784) [in whole cluster]
complement(8..784) [in contig]
TypeCDS
Length777 bp (258 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category3.4 other modification
Productputative cyclase
Product (GenBank)cyclase
Gene
Gene (GenBank)cmmY
EC number
Keyword
  • 2nd and 3rd ring
Note
Note (GenBank)
Reference
ACC
PmId
[15112992] Biosynthesis of the antitumor chromomycin A3 in Streptomyces griseus: analysis of the gene cluster and rational design of novel chromomycin analogs. (Chem Biol. , 2004)
Related Reference
ACC
Q9L4U2
NITE
Acla_00250
PmId
[12715874] Studies on a second and third ring cyclization in anthracycline biosynthesis. (J Antibiot (Tokyo). , 2003)
ACC
Q9RN54
NITE
Nogl_00250
PmId
[11683270] The entire nogalamycin biosynthetic gene cluster of Streptomyces nogalater: characterization of a 20-kb DNA region and generation of hybrid structures. (Mol Genet Genomics. , 2001)
[12715874] Studies on a second and third ring cyclization in anthracycline biosynthesis. (J Antibiot (Tokyo). , 2003)
ACC
O68500
NITE
Adria_00160
PmId
[9573189] The Streptomyces peucetius dpsY and dnrX genes govern early and late steps of daunorubicin and doxorubicin biosynthesis. (J Bacteriol. , 1998)
[10419974] The Streptomyces peucetius dpsC gene determines the choice of starter unit in biosynthesis of the daunorubicin polyketide. (J Bacteriol. , 1999)

close this sectionSequence

selected fasta
>putative cyclase [cyclase]
MRIIDLSTPIDASAWEPEPVEHHVMSAADGAKHMSEEMRTHFGVEFDPSVLPGGELLSID
TLSLTTHTGTHIDAPSHYGSTATYGDGRPRHIDELPLEWFHGPGVVLDLTGAGTGAVDAA
FVRRQLERIGHVVSAGEIVLLRTGASRLSGTPAYFTDFTGLDGSATHYLLDHGVRVIGTD
AFSLDAPFRHMIEHYQRTGEAGALWPAHFAGRDREYCQIERLANLESLPAPTGFDVSCFP
VKIAGAGAGWARAVALVP
selected fasta
>putative cyclase [cyclase]
ATGCGGATCATCGACCTCTCCACCCCGATCGACGCCTCGGCCTGGGAGCCCGAGCCCGTC
GAGCACCATGTGATGAGCGCCGCCGACGGCGCCAAGCACATGAGCGAGGAGATGCGCACG
CACTTCGGTGTGGAGTTCGACCCCTCGGTACTGCCCGGCGGGGAGTTGCTGTCGATCGAC
ACGCTGAGCCTCACCACCCACACCGGCACGCACATCGACGCGCCCTCGCACTACGGCTCA
ACGGCGACCTACGGCGACGGACGGCCCCGCCACATCGACGAGCTGCCACTGGAGTGGTTC
CACGGCCCCGGGGTGGTCCTGGACCTGACCGGGGCAGGTACCGGTGCGGTGGATGCGGCG
TTCGTCCGCCGTCAGCTGGAACGGATCGGCCACGTCGTGAGCGCGGGCGAGATCGTGCTG
CTCCGCACCGGCGCGTCCAGGCTCTCCGGCACCCCTGCCTACTTCACGGACTTCACCGGC
CTGGACGGGTCGGCCACCCACTACCTCCTGGACCACGGAGTGCGGGTGATCGGCACGGAC
GCGTTCAGCCTGGACGCACCCTTCCGCCACATGATCGAGCACTACCAGCGGACCGGCGAA
GCCGGTGCCCTCTGGCCCGCCCACTTCGCGGGCCGTGACCGGGAGTACTGCCAGATAGAA
CGCCTCGCCAACCTGGAGTCACTCCCGGCTCCCACCGGCTTCGACGTGAGCTGCTTCCCC
GTGAAGATCGCGGGGGCGGGCGCGGGCTGGGCCCGGGCCGTGGCACTGGTGCCCTGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09
show BLAST table
InterPro
Database:interpro:38.0
IPR007325 Putative cyclase (Family)
 [3-187]  1e-38 PF04199
PF04199   Cyclase
SignalP
 [1-14]  0.066 Signal
Bacteria, Gram-negative   
TMHMM No significant hit
first first   Chro_00020 Chro_00020